Q开关Nd:YAG激光治疗色素增加性皮肤病128例临床疗效分析

目的：观察Q开关Nd：YAG激光治疗色素增加性皮肤病临床疗效与美容效果以及治疗次数。方法：Q开关Nd：YAG激光(1064nm、532nm波长)治疗128例色素增多性皮肤病，观察并分析其疗效和美容效果。结果：Q开关Nd：YAG激光治疗色素增多性皮肤病的治疗有效。其中对文眉、雀斑、脂溢性角化、色素痣等总有效率为96％以上，治疗次数为1-4次。结论：Q开关Nd：YAG激光治疗色素增加性皮肤病特别是错误文眉治疗效果好。     

Q开关Nd:YAG激光治疗面部色素增加性病变疗效分析

目的:观察Q开关Nd:YAG激光治疗面部色素增加性皮肤病的临床疗效及副反应。方法:使用Q开关Nd:YAG激光治疗145例色素增加性皮肤病患者。雀斑、咖啡斑和脂溢性角化病采用波长532nm,太田痣和文身采用波长l 064nm。结果:145例患者经治疗后,色素性病变逐渐消退,其中文身、雀斑、脂溢性角化病疗效较为显著。结论:Q开关Nd:YAG激光治疗色素增加性皮肤病疗效好,安全有效,是一种无创的治疗方法。     

Q开关Nd：YAG激光和CO2激光治疗面部色素痣疗效比较

目的：观察、评价Q开关Nd:YAG激光治疗面部色素痣的治疗效果与美容效果。方法：以Q开关Nd:YAG激光（1064nm,532nm波长）和CO2激光分别对433例面部色素痣患者1458个皮损进行治疗,对照观察其治疗效果,美容效果和平均治愈次数。结果：Q开关激光组Ⅰ、Ⅱ级痊愈率为90．67％,平均治愈次数2．59次,CO2激光组为40．4％,平均治愈次数为1．85次,经统计学处理有显著差异,结论：Q开关Nd:YAG激光治疗面部色素痣,有显著的治疗效果和美容效果,CO2激光治疗面部色素痣治疗效果较好,但美容效果欠佳。     

Q开关Nd：YAG激光治疗色素性皮肤病5000例疗效观察

目的：观察Q开关Nd：YAG激光治疗色素性皮肤病的疗效、影响因素及副反应。方法：使用Q开关Nd：YAG激光治疗色素性皮肤病患者5000例,浅表性色素损害雀斑、咖啡斑和老年斑采用Q532nm波长,太田痣和文身采用Q1064nm波长。结果：本组患者经1～6次治疗,总有效率达96．14％,术后出现暂时性色素沉着269例（5．38％）,无瘢痕发生。结论：Q开关Nd：YAG激光治疗色素性皮肤病疗效较好,安全性高。     

Q开关1064nm激光治疗雀斑的临床疗效观察

目的观察Q开关1064nm激光治疗Ⅳ型皮肤或混合黄褐斑的雀斑患者的临床疗效。方法采用Q-开关Nd：YAG Spectra VRM Ⅲ激光,波长1064nm,光斑尺寸3mm,脉宽5～7ns,能量3．0～3．6J／cm2,对50例雀斑患者进行治疗。每月1次,共治疗3次,末次治疗后评价患者雀斑的疗效。结果50例患者经过3次治疗后,35例（70）基本完全消退,10例（20％）明显消退,5例（10％）好转,总有效率为100％。所有患者面部治疗区域无色素沉着、色素减退等不良反应出现,混合黄褐斑的雀斑患者未见加重。结论采用Q开关1064nm激光治疗Ⅳ型皮肤或混合黄褐斑的雀斑患者疗效显著、安全,不良反应少。     

穴位埋线及面部围刺联合Q开关Nd:YAG激光治疗气滞血瘀型黄褐斑的临床研究

目的：观察穴位埋线及面部围刺联合Q开关Nd:YAG激光治疗气滞血瘀型黄褐斑的临床治疗效果。方法：收集气滞血瘀型黄褐斑患者60例，随机分为治疗组和对照组，每组30例，对照组予以Q开关Nd:YAG激光治疗，治疗组在Q开关激光治疗的基础上配合穴位埋线及面部围刺，Q开关激光治疗每月1次，穴位埋线每2周1次，面部围刺每5天治疗1次，共治疗5个月后观察患者MASI评分、中医症候总积分及细则积分，计算皮损消退率和中医症候改善有效率。结果：两组治疗后的MASI评分均较治疗前有明显下降（P<0.01），治疗组效果优于对照组，差异有统计学意义（P<0.05）；治疗后，治疗组中医症候总积分及细则积分均较治疗前明显下降（P<0.01），而对照组在中医细则积分中仅面部色斑治疗前后差异有统计学意义（P<0.01），其余均无明显改善，差异无统计学意义（P>0.05）；治疗组和对照组皮损消退有效率分别为90.0%和60.0%，差异有统计学意义（P<0.05）；治疗组和对照组中医症候改善有效率分别为93.0%、16.6%，差异有统计学意义（P<0.01）。结论：穴位埋线及面部围...     

低能量Q开关Nd:YAG激光联合胶原贴敷料治疗面部寻常性痤疮疗效观察

目的:观察低能量Q开关Nd:YAG激光联合胶原贴敷料治疗面部寻常性痤疮的临床疗效。方法:98例寻常性痤疮患者,采用半侧面部对照观察,分为两组。治疗组:左侧面部,先用粉刺针清除皮损,再采用低能量Q开关Nd:YAG激光联合使用胶原贴敷料治疗;对照组:右侧面部,采用低能量Q开关Nd:YAG激光联合使用胶原贴敷料治疗。激光治疗两周1次,6次为1个疗程。98例患者均进行1个疗程的Q开关Nd:YAG激光治疗,观察治疗后皮损改善的效果及不良反应。结果:治疗组痤疮皮损改善有效率(90.82%)明显高于对照组(71.43%),两组差异有统计学意义(P0.01),两组患者在激光治疗后均配合使用胶原贴敷料,能明显缓解患者皮肤的灼热感及干燥敏感。结论:低能量Q开关Nd:YAG激光联合胶原贴敷料治疗面部寻常性痤疮,面部先用粉刺针清除皮损,联合治疗效果确切,且不良反应发生率低。     

Q开关Nd:YAG激光联合强脉冲光治疗雀斑临床观察

目的:寻找临床上对雀斑的最佳治疗方法。方法:采用Q开关倍频Nd:YAG激光和强脉冲光联合治疗雀斑,进行疗效观察,并与继往单纯采用Q开关激光治疗的病例进行疗效对比研究。结果:单纯用Q开关激光治疗的224例雀斑患者,痊愈178例(79.5%),采用Q开关激光联合强脉冲光治疗的52例雀斑患者,痊愈50例(96.2%)。两组痊愈率之间差异有显著性。结论:采用激光与强脉冲光联合治疗雀斑疗效好、副作用小,值得临床推广。     

强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗面部雀斑疗效观察

目的:观察强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗面部雀斑的临床效果。方法:选取笔者医院2017年5月-2019年5月收治的126例雀斑患者,随机分为观察组和对照组,每组63例。对照组采用强脉冲光治疗,观察组采用强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗,观察两组治疗后的临床效果。结果:观察组临床总有效率明显高于对照组(χ^2=12.86,P<0.01),观察组治疗总次数明显低于对照组(t=3.928,P<0.05),复发率也明显低于对照组(χ^2=4.189,P<0.05),患者对治疗满意度明显高于对照组(χ^2=13.945,P<0.01),两组不良反应发生率无明显差异(χ^2=0.099,P>0.05)。结论:强脉冲光联合Q开关倍频Nd:YAG 532nm激光治疗雀斑复发率低、治疗次数少、安全性高,临床效果显著,值得在临床上推广使用。     

Q开关Nd:YAG激光治疗雀斑148例

雀斑是染色体显性遗传性疾病，多见于女性。好发于面部特别是鼻梁部及眶下，皮肤损害为浅褐色或暗褐色斑点，呈针尖至米粒大小，圆形或不规则形，深浅不一，边缘不规则，不融合，与日晒关系明显。2002年2月～2005年6月，笔者应用Q开关Nd：YAG激光治疗雀斑患者148例，取得了满意疗效，现报道如下。     

A simple way to take pictures during endoscopic procedures

PURPOSE: We describe a new method of taking pictures from endoscopic images using a digital photo camera coupled to the endoscopic lens without an adapter. MATERIALS AND METHODS: We used a digital camera with 3.3 megapixel resolution and 6 x optical zoom. The camera was coupled to the endoscopic lens with no special adapter. The image was accompanied through the LCD (liquid crystal display) visor, and the picture was taken with the flash button on and with no macro resource. The image was then enlarged by optical and digital zoom before being easily stored in photo files at the personal computer. RESULTS: The quality of the photos obtained by this method was at least similar to that of traditional photos, and the data were promptly stored. CONCLUSIONS: We describe a simple method of taking pictures from endoscopic images with the additional advantage of a facility to edit and store the photographs.     

Efficacy and safety of fractional carbon dioxide laser for treatment of unwanted facial freckles in phototypes II–IV: a pilot study

Facial freckles are a cosmetic concern to Egyptians, particularly young females. Several therapeutic lines exist with variable response rates and limitations. Fractional carbon dioxide (FCO₂) laser provides minimal ablation and therefore less down time and less side effects. The efficacy and safety of this laser technology have still not been studied in freckles. The aim of this study is to assess the efficacy and safety of FCO₂ laser in the treatment of unwanted facial freckles in Egyptians. Twenty patients undergone a single session of FCO₂ laser and then were followed up clinically a month later. Photographs were taken before treatment and at follow-up visit and were assessed by three blinded investigators. Percent of global improvement was measured on a 4-point grading scale. Patient’s satisfaction and adverse events were recorded. Two patients (10 %) showed grade 1 improvement, while eight patients (40 %) showed grade 2 improvement. Nine patients (45 %) showed grade 3 improvement, and only one patient (5 %) showed grade 4 improvement. FCO₂ laser resurfacing is effective and safe in treatment of facial freckles in skin phototypes II–IV. It can offer a more practical alternative to topical treatments, and a cheaper alternative to Q-switched lasers.     

Microcomputer image processing in gastrointestinal endoscopy

A computer-based system was developed to handle information and endoscopic images in a clinical setting. The system is based on an 80286 AT computer whose topology includes a 16-bit color image capture/display graphics adapter and a 256 gray scale 8-bit digital image analysis processor. Using its color capabilities, one may initiate a picture database of patient's endoscopic images, x rays, and relevant clinical data. The computer-based imaging system allows instant access to this information and minimizes subjective evaluation, improving comparison and follow-up of treatments in a more objective manner. The image analysis components permit digital characterization of lesions, which allows online measurements and image enhancement. This is a cost-effective method of handling information and images in the clinical setting, facilitating endoscopic management and follow-up of the patient with gastrointestinal disease, as well as an effective research and teaching tool.     

Medlite激光治疗雀斑及雀斑样痣的临床观察

目的 探讨应用Medlite四波长激光仪治疗雀斑及雀斑样痣的临床疗效。方法 应用Medlite四波长美肤激光治疗仪，采用的波长为532 nm和1 064 nm，治疗雀斑及雀斑样痣490例患者，并根据患者皮肤特点选择适当的治疗参数，将光斑准确地发射到皮损表面，以治疗后的皮肤呈白色为适度。1个月后可重复治疗。结果 490例患者中，457例雀斑患者经1～3次治疗后均痊愈，约15%的患者治疗后出现暂时性色素沉着或色素减退，1～6个月自然消退。33例雀斑样痣患者经1～8次治疗后均显效。结论 Medlite激光治疗雀斑疗效确切无瘢痕，治疗后皮肤反应轻微，效果满意，但对雀斑样痣疗效稍差。     

Image processing and quantitative assessment in computer tomography for non-surgical treatment of brain tumours

Summary Using the EMI computer tomographic (CT) system, EMI-1010, a series of new programmes were developed for the digital analysis of the CT images in order to make a more objective and quantitative assessment possible of two nonsurgical methods of treatment of brain tumours such as irradiation and chemotherapy.Amongst the various therapeutic effects demonstrable from the CT data, a reduction of the mass effect was found to lower the average CT number, with a dilatation of the cisterns and ventricles. In contrast, an improvement in the amount of perifocal oedema increased the average CT number of the region, however the changes in CT number of the tumour itself may be variable. The separate evaluation of these factors, therefore, gives more information about the results of the treatment than a simple analysis of the histogram of the region.Circumscribed tumours are fairly well evaluated with our programme for the statistical analysis of the volume and the CT weight of tumours and the degree of contrast enhancement using histograms and subtraction scans. For the digital analysis of the ventricular system, the subarachnoid space, perifocal oedema, and irregularly shaped infiltrating tumours, our programmes for the character-image print-out and edge correction for the partial-volume effect of skull and air are much more useful than the CRT display for data extraction and geographic-pattern recognition.     

Successful Removal of Freckles in Asian Skin with a Q-Switched Alexandrite Laser

BACKGROUND.: Although freckles are light-brown macules most frequently observed in individuals with red or blond hair and blue or gray eyes, freckles are common to Asian people, including Koreans. Treatment may be requested on cosmetic grounds. OBJECTIVE.: The objective of this study was to determine the effectiveness of the Q-switched alexandrite laser (wavelength 755 nm; pulse width 100 nsec) in treating the 197 cases of Asian skin with freckles and to observe any side effects such as pigmentary changes or scarring. METHODS.: One hundred ninety-seven patients with freckles were treated with the Q-switched alexandrite laser at 8-week intervals and clinically analyzed. RESULTS.: More than 76% removal of freckles required an average of 1.5 treatment sessions with 7.0 J/cm2. No scarring, long-standing pigmentary changes, or textural changes were seen in laser-irradiated skin. CONCLUSION.: The Q-switched alexandrite laser is a safe and highly effective modality for removing freckles without scarring or permanent pigmentary changes in Asian skin.     

Comparison of short-pulsed and long-pulsed 532 nm lasers in the removal of freckles

The purpose of this study was to compare the efficacy and safety of the 532 nm long-pulsed laser (10 ms) with that of the 532 nm short-pulsed laser (10 ns) for freckle removal. Currently, the gold standard for treatment is the short-pulsed laser. Recently, several long-pulsed lasers have been introduced for both hair removal and the treatment of freckles. To our investigative team’s knowledge, no controlled experiments have been performed to compare the safety and efficacy of long-pulsed versus short-pulsed lasers for the treatment of freckles. This was a 4-week trial, and all patients had three freckles that were randomly allocated to be treated with short-pulse laser, long-pulse laser, or to receive no treatment (control). All patients had three freckles that were randomly selected to be treated with short-pulse 532 nm Medlite IV laser (10 n, 1 J/cm²), or long-pulse 532 nm Aura laser (10 ms, 1 J/cm²) or to remain as a control (no treatment). The laser treatment was only performed once, followed by a 1-day and a 1-month follow-up visit. Freckle size was determined by a novel surface area measurement technique that was created by our research staff. The study included 17 sets of freckles (three in each set). All of the lesions which received the short-pulsed laser treatment had immediate whitening of the lesions, which turned into dry scabs the next day. None of the freckles treated in the long-pulsed group or control group developed immediate whitening or scabs. No blisters or ulcers developed. The average pain score in the short-pulsed laser group was 2–3 out of 10, while it was 0 out of 10 in the long-pulsed laser group. All scabs that developed in the short-pulsed laser group fell off between days 6 and 12 (average 8 days). The outcome of this study verified the appropriate treatment of freckles. The study confirmed that when the same energy settings, short-pulsed laser is the more effective laser treatment regimen (when compared with the long-pulsed laser), with high tolerability and minimal side effects for patients with skin types I to IV.     

新型强脉冲光治疗面部雀斑的疗效观察

目的:观察新型强脉冲光治疗面部雀斑的临床疗效及安全性。方法:采用Lovel yerⅡ强脉冲光AFT 570～950nm,AFT 540～950nm,光斑面积16mm×40mm.脉宽10、12、15ms,能量密度14～19J/cm2,患者经3～5次治疗,两次治疗间隔时间3周,随访观察3～12个月。结果:21例雀斑患者经过治疗后10例(48%)基本完全消退,11例(52%)明显消退,总有效率100%。所有患者面部治疗区域皮肤较以前更光滑、细腻,未出现不良反应。结论:新型强脉冲光对雀斑的治疗,安全、有效,可以达到理想的治疗效果。