Characterization of solid breast masses: use of the sonographic breast imaging reporting and data system lexicon.

OBJECTIVE: The purpose of this study was to determine the reliability of sonographic American College of Radiology Breast Imaging Reporting And Data System (BI-RADS) classification in differentiating benign from malignant breast masses. METHODS: One hundred seventy-eight breast masses studied by sonography with a known diagnosis were reviewed. All lesions were classified according to the sonographic BI-RADS lexicon. Pathologic results were compared with sonographic features. Sensitivity, specificity, accuracy, and positive predictive value (PPV) and negative predictive value (NPV) for the sonographic BI-RADS lexicon were calculated. RESULTS: Twenty-six cases were assigned to class 3, 73 to class 4, and 79 to class 5. Pathologic results revealed 105 malignant and 73 benign lesions. The sonographic BI-RADS lexicon showed 71.3% accuracy, 98.1% sensitivity, 32.9% specificity, 67.8% PPV, and 92.3% NPV. The NPV for class 3 was 92.3%. The PPVs for classes 4 and 5 were 46.6% and 87.3%. Typical signs of malignancy were irregular shape, antiparallel orientation, noncircumscribed margin, echogenic halo, and decreased sound transmission. Typical signs of benignity were oval shape and circumscribed margin. CONCLUSIONS: The sonographic BI-RADS lexicon is an important system for describing and classifying breast lesions.     

Ultrasonography by emergency physicians in patients with suspected ureteral colic

We performed a prospective study of patients with suspected ureteral colic to evaluate the test characteristics of bedside renal ultrasonography (US) performed by emergency physicians (EPs) for detecting hydronephrosis, and to evaluate how US can be used to predict the likelihood of nephrolithiasis. Thirteen EPs performed US, recorded the presence of hydronephrosis, and made an assessment of the likelihood of nephrolithiasis. All patients underwent i.v. pyelography (IVP) or unenhanced helical computed tomography (CT). There were 126 patients in the study: 84 underwent IVP; 42 underwent helical CT. Test characteristics of bedside US for detecting hydronephrosis were: sensitivity 72%, specificity 73%, positive predictive value (PPV) 85%, negative predictive value (NPV) 54%, accuracy 72%. The PPV and NPV for the ability of the EP to predict nephrolithiasis after performing US were 86% and 75%, respectively. We conclude that bedside US performed by EPs may be used to detect hydronephrosis and help predict the presence of nephrolithiasis.     

Confirmation of endotracheal intubation by combined ultrasonographic methods in the emergency department

Objectives: The objective of the present study was to investigate whether the combined use of transcricothyroid membrane ultrasonography and ultrasonographic evaluation for pleural sliding is useful for verifying endotracheal intubation in the ED. Methods: We performed a prospective clinical trial in the ED from January to July 2008. All patients enrolled in the present study had been admitted to the ED owing to severe airway problems. A linear probe was placed horizontally over the cricothyroid membrane (dynamic phase) during the intubation process. Endotracheal intubation was confirmed by ultrasonographic lung sliding. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated. Results: Thirty patients (17 men, 13 women; mean age 59.6 ± 16.7 [SD] years) were enrolled in the study. Of the 30, 7 had a history of trauma. Four trauma patients were diagnosed with haemopneumothorax. The ratio of initial oesophageal‐to‐endotracheal intubation was 3:27. Sensitivity, specificity, PPV and NPV for endotracheal intubation were 96.3%, 100%, 100% and 75%, respectively. After verification by ultrasonographic lung sliding, sensitivity, specificity, PPV and NPV were each 100%. Conclusions: The combination of transcricothyroid membrane ultrasonography and ultrasonographic lung‐sliding evaluation could be useful in confirming endotracheal intubation in the ED.     

Sonohysterography of the uterine cavity: Preliminary investigations

Objective: To compare sonohysterography (SH), in the exploration of the uterine cavity, with classical transvaginal sonography (TVS), hysterography (HSG), and hysteroscopy. Study design: 104 consecutive patients evaluated for uterine disorders underwent both TVS and SH. SH was obtained by distension of the uterine cavity with the instillation of an isotonic saline solution; 36 patients also underwent HSG; 82 women underwent surgery. Histologic findings were considered as gold standard. The criteria used to compare these methods were sensitivity, specificity, and negative and positive predictive values (NPV, PPV) for identifying pathology. Results: 3 instillation failures occurred. SH was found to be more effective (sensitivity 94%, specificity 98%) than HSG (sensitivity 67%, specificity 94%). The difference between TVS and SH was less marked, SH showing some superiority (sensitivity 88%, specificity 98%) to TVS (sensitivity 77%, specificity 93%). Conclusion: SH represents an improvement over conventional TVS and is fully capable of replacing HSG for the study of the uterine cavity. © 1995 John Wiley & Sons, Inc.     

Short- and long-term effects of emergency medicine sonography on formal sonography use: a decade of experience.

OBJECTIVES: It has been reported that use of formal sonographic studies by departments of radiology initially increases after inception of an emergency medicine (EM) sonography training program, but there are no data on whether this trend continues as the training program matures. The purpose of this study was to evaluate the effect of an ongoing EM sonography program on formal sonography use after more than a decade of experience. METHODS: This retrospective, computer-assisted review compared emergency department (ED) abdominal sonographic studies ordered in the 3 years before inception of an EM sonography program (1992-1994) with those ordered in the 8 years after its inception (1995-2002). To determine the relative change, all abdominal sonograms ordered by ED physicians were compared with equivalent outpatient formal sonograms by all other physicians in the hospital. The study site is a community teaching hospital with a current ED census of 50,000. RESULTS: In the initial 4 years (1995-1998), the number of formal studies increased significantly in both absolute numbers (annual mean, 95 versus 162; P < .002) and as a percentage of all outpatient sonograms ordered at the institution (5.1% versus 8.5%; P < .0001). However, in the following 4 years (1999-2002), the absolute number of formal studies remained constant but decreased when adjusted for an increased ED census. Emergency department-ordered formal studies also decreased as a percentage of all sonograms ordered (5.1% versus 4.1%; P = .002). CONCLUSIONS: Emergency department use of formal sonography services increases with the introduction of ED sonography but decreases markedly as the program matures.     

Sonography in the Evaluation of Acute Appendicitis

Objective. The purpose of this study was to evaluate the negative predictive value (NPV) of sonography in the diagnosis of acute appendicitis. Methods. Right lower quadrant sonograms of 193 patients (158 female and 35 male; age range, 3–20 years) with suspected acute appendicitis over a 1‐year period were retrospectively reviewed. Sonographic findings were graded on a 5‐point scale, ranging from a normal appendix identified (grade 1) to frankly acute appendicitis (grade 5). Sonographic findings were compared with subsequent computed tomographic (CT), surgical, and pathologic findings. The diagnostic accuracy of sonography was assessed considering surgical findings and clinical follow‐up as reference standards. Results. Forty‐nine patients (25.4%) had appendicitis on sonography, and 144 (74.6%) had negative sonographic findings. Computed tomographic scans were obtained in 51 patients (26.4%) within 4 days after sonography. These included 39 patients with negative and 12 with positive sonographic findings. Computed tomography changed the sonographic diagnosis in 10 patients: from negative to positive in 3 cases and positive to negative in 7. Forty‐three patients (22.2%) underwent surgery. The surgical findings were positive for appendicitis in 37 (86%) of the 43 patients who had surgery. Patients with negative sonographic findings who, to our knowledge, did not have subsequent CT scans or surgery were considered to have negative findings for appendicitis. Seven patients with negative sonographic findings underwent surgery and had appendicitis; therefore, 137 of 144 patients with negative sonographic findings did not have appendicitis. On the basis of these numbers, the NPV was 95.1%. Conclusions. Sonography has a high NPV and should be considered as a reasonable screening tool in the evaluation of acute appendicitis. Further imaging could be performed if clinical signs and symptoms worsen.     

Confirmation of Endotracheal Tube Placement after Intubation Using the Ultrasound Sliding Lung Sign

Objectives: To evaluate the performance of the ultrasound (US) sliding lung sign as a predictor of endotracheal tube (ETT) placement. Many other tools and examination findings have been used to confirm ETT placement; erroneous placement of the ETT has even been confirmed by US. Methods: This was a laboratory study using fresh, recently dead cadavers. Cadavers were obtained at a medical school anatomy laboratory on the basis of availability during a four‐month period. Subjects who died from significant trauma or after thoracic surgery were excluded. A numerical randomization tool was used to direct where the tube would be placed on intubation. Laryngoscopy was performed, and the ETT was placed in the esophagus, in the trachea, or in the right main stem (RMS) bronchus. Placement was confirmed by direct laryngoscopic visualization of ETT passage through vocal cords or with fiber optic visualization, as needed. US images of the sliding lung sign, sliding of visceral and parietal pleura past each other, were taken on both sides of the chest at the mid axillary line during ventilation with an ambu bag. Two board‐certified emergency physicians with hospital credentialing in emergency US used a 4‐2 MHz micro‐convex transducer on a Sonosite 180 Plus for imaging. The sonologists were blinded to the location of the endotracheal tube and imaged and recorded their results individually. A positive sliding lung sign was taken to signify lung expansion with ventilation in a hemithorax. Endotracheal versus esophageal ETT placement, as well as tracheal versus RMS, was determined on the basis of sliding lung findings on both sides of the chest. Interpreter agreement, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratios (LHR) were calculated for tracheal (including RMS) versus esophageal, as well as main trachea versus RMS intubation. Results: Nine cadavers yielded 68 intubations. For esophageal versus tracheal (including RMS) intubation, sonologist 1 (S1) had a sensitivity of 95.4% (95% CI = 84.2% to 99.4%), a specificity of 100% (95% CI = 86.3% to 100%), an NPV of 92.6% (95% CI = 75.7% to 99.1%), and a PPV of 100% (95% CI = 91.4% to 100%) with an LHR of 0.05 (95% CI = 0.01 to 0.2) for a negative test. Sonologist 2 (S2) had a sensitivity of 100% (95% CI = 91.8% to 100%), a specificity of 100% (95% CI = 86.3% to 100%), an NPV of 100% (95% CI = 86.3% to 100%), and a PPV of 100% (95% CI = 91.8% to 100%); agreement was 97% (κ= 0.94; 95% CI = 0.7 to 1.2). In RMS versus tracheal, S1 had a sensitivity of 69.2% (95% CI = 48.2% to 85.7%), a specificity of 93.3% (95% CI = 68.1% to 99.8%), a PPV of 94.7% (95% CI = 73.9% to 99.9%), and an NPV of 63.6% (95% CI = 40.7% to 82.8%) with an LHR for a positive test of 10.4 (95% CI = 2.2 to 59.1) and of 0.4 (95% CI = 0.2 to 0.6) for negative test. S2 had a sensitivity of 78.6% (95% CI = 59.1% to 91.7%), a specificity of 100% (95% CI = 78.2% to 100%), a PPV of 100% (95% CI = 84.6% to 100%), NPV of 71.4% (95% CI = 47.8% to 88.7%), with an LHR for a negative test of 0.2 (95% CI = 0.1 to 0.4); agreement was 85.9% (κ= 0.6; 95% CI = 0.4 to 0.9). Conclusions: These results show that US imaging of the sliding lung sign in a cadaver model is an accurate method for confirmation of ETT placement. Further, the technique may have some utility in differentiating RMS bronchus from main tracheal intubations.     

Comparison of the Medical Priority Dispatch System to an Out-of-hospital Patient Acuity Score

Background: Although the Medical Priority Dispatch System (MPDS) is widely used by emergency medical services (EMS) dispatchers to determine dispatch priority, there is little evidence that it reflects patient acuity. The Canadian Triage and Acuity Scale (CTAS) is a standard patient acuity scale widely used by Canadian emergency departments and EMS systems to prioritize patient care requirements. Objectives: To determine the relationship between MPDS dispatch priority and out‐of‐hospital CTAS. Methods: All emergency calls on a large urban EMS communications database for a one‐year period were obtained. Duplicate calls, nonemergency transfers, and canceled calls were excluded. Sensitivity and specificity to detect high‐acuity illness, as well as positive predictive value (PPV) and negative predictive value (NPV), were calculated for all protocols. Results: Of 197,882 calls, 102,582 met inclusion criteria. The overall sensitivity of MPDS was 68.2% (95% confidence interval [CI] = 67.8% to 68.5%), with a specificity of 66.2% (95% CI = 65.7% to 66.7%). The most sensitive protocol for detecting high acuity of illness was the breathing‐problem protocol, with a sensitivity of 100.0% (95% CI = 99.9% to 100.0%), whereas the most specific protocol was the one for psychiatric problems, with a specificity of 98.1% (95% CI = 97.5% to 98.7%). The cardiac‐arrest protocol had the highest PPV (92.6%, 95% CI = 90.3% to 94.3%), whereas the convulsions protocol had the highest NPV (85.9%, 95% CI = 84.5% to 87.2%). The best‐performing protocol overall was the cardiac‐arrest protocol, and the protocol with the overall poorest performance was the one for unknown problems. Sixteen of the 32 protocols performed no better than chance alone at identifying high‐acuity patients. Conclusions: The Medical Priority Dispatch System exhibits at least moderate sensitivity and specificity for detecting high acuity of illness or injury. This performance analysis may be used to identify target protocols for future improvements.     

Detection of soft tissue foreign bodies in the presence of soft tissue gas.

OBJECTIVE: To determine the effect of soft tissue gas on the accuracy of foreign body detection by realtime sonography. METHODS: This was a prospective randomized study using glass, metal, and bone inserted into turkey breasts to simulate human soft tissue foreign bodies. Air was subsequently injected around a random selection of the foreign bodies to simulate soft tissue gas that can accompany a blast or high-force injury. Using a linear transducer, physicians credentialed in the use of sonography were each asked to scan the breasts, identify the location of any foreign body, and describe whether the object located was bone, metal, or glass. They were also asked to describe the characteristics of the foreign body, including surface echogenicity, visibility, and artifacts, if any. RESULTS: The sensitivity for localization of each foreign body by each sonographer was 100% (48 of 48) and was unaffected by the presence of soft tissue gas. The accuracy of classifying the foreign body was poor except with bone. Glass and metal were often confused with each other. With the addition of soft tissue gas over the foreign bodies, the sensitivity of classifying the foreign body was decreased further from a combined 58% to 28%. The presence of soft tissue gas decreased the amount of reflection of the foreign body and obscured the subtle differences in the brightness of each foreign body, leading to a decrease in the accuracy of identification but not localization of the foreign body. CONCLUSIONS: In an experimental model, soft tissue gas does not affect the localization of soft tissue foreign bodies. However, correct identification of the type of foreign body is limited by soft tissue gas because of loss of the typical sonographic characteristics.     

Comparative study of transvaginal ultrasonography and CA 125 in the preoperative evaluation of myometrial invasion in endometrial carcinoma.

OBJECTIVE: To compare the ability of transvaginal sonography and serum CA 125 levels to predict myometrial invasion in patients with endometrial carcinoma. DESIGN AND METHODS: Prospective study in 50 consecutive patients (mean age 60 years, SD 10.5, range 29-77 years) diagnosed as having endometrial cancer and scheduled for surgical staging. All patients were evaluated by transvaginal ultrasonography. Endometrial thickness was measured in all cases and myometrial invasion was estimated as < 50% or > or = 50%. Serum CA 125 level was determined in each patient. A cut-off level of > or = 35 IU/ml was considered to predict myometrial invasion of > or = 50%. All patients underwent surgical staging, and definitive histopathological findings regarding myometrial invasion were used as the 'gold standard'. Sensitivity, specificity and positive predictive value (PPV) and negative predictive value (NPV) were calculated for transvaginal ultrasonography and CA 125 and compared. RESULTS: On histopathological analysis, myometrial invasion was found to be < 50% in 35 (70%) cases and > or = 50% in 15 cases (30%). Mean endometrial thickness in patients with superficial invasion was significantly lower than in those with deep invasion (13.4 mm (95% CI 11.2-15.7) vs. 18.7 mm (95% CI 15.0-22.3), respectively; p = 0.014). Median CA 125 was significantly higher in patients with deep invasion than in those with superficial invasion (30 IU/ml, interquartile range (IQR) 46.0 vs. 16.9 IU/ml, IQR 13.9, respectively; p = 0.002). The sensitivity, specificity, PPV and NPV for transvaginal ultrasonography were 86.7% (95% CI 59.5-98.3), 94.3% (95% CI 80.8-99.3), 86.7% (95% CI 59.5-98.3) and 94.3% (95% CI 80.8-99.3), respectively. The sensitivity, specificity, PPV and NPV for CA 125 were 40% (95% CI 16.3-67.7), 91.4% (95% CI 76.9-98.2), 66.7% (95% CI 29.9-92.5) and 78% (95% CI 63.4-89.5), respectively. The sensitivity of transvaginal ultrasonography was significantly higher than that of CA 125 (p = 0.008). No differences were found in terms of specificity, PPV or NPV. CONCLUSION: Our results indicate that transvaginal ultrasonography is more sensitive than CA 125 in predicting myometrial invasion in endometrial cancer.     

超声联合BRAFV600E检测对BSRTC Ⅲ类甲状腺结节的诊断价值

目的探讨超声甲状腺影像报告与数据系统（TIRADS）联合BRAF^V600E检测对甲状腺细胞病理学Bethesda报告系统（BSRTC）Ⅲ类结节的诊断价值。 方法选取2016年1月至2019年6月在南京医科大学第一附属医院行超声引导下甲状腺FNA的患者125例,共125个BSRTC Ⅲ类结节。所有结节同时行TIRADS分类和BRAF^V600E检测,并经手术病理证实。以手术病理结果为金标准,比较TIRADS、BRAF^V600E检测及两者联合对BSRTC Ⅲ类甲状腺结节的诊断价值。 结果125例患者共计纳入125个甲状腺结节,术后病理结果提示：良性结节76个;恶性结节49个。TIRADS 4c~5鉴别诊断BSRTC Ⅲ类结节良恶性的敏感度、特异度、阳性预测值、阴性预测值及准确性分别为73.5%、89.5%、81.8%、84.0%、83.2%。BRAF^V600E突变检测鉴别BSRTC Ⅲ类结节良恶性的敏感度、特异度、阳性预测值、阴性预测值及准确性分别为75.5%、100.0%、100.0%、86.4%、90.4%。以TIRADS 4c~5类或BRAF^V600E突变型为BSRTC Ⅲ类结节恶性的联合诊断标准,其敏感度、特异度、阳性预测值、阴性预测值及准确性分别为93.9%、89.5%、85.2%、95.8%、91.2%,联合诊断较TIRADS、联合诊断较BRAF^V600E具有较高的敏感度（P=0.002,P=0.004）、阴性预测值（P=0.018,P=0.044）。 结论TIRADS和BRAF^V600E检测联合对于BSRTC Ⅲ类结节具有良好的诊断效能,尤其诊断敏感度和阴性预测值高于单独应用TIRADS或BRAF^V600E检测。     

Ultrasonography by emergency physicians in patients with suspected ureteral colic

We performed a prospective study of patients with suspected ureteral colic to evaluate the test characteristics of bedside renal ultrasonography (US) performed by emergency physicians (EPs) for detecting hydronephrosis, and to evaluate how US can be used to predict the likelihood of nephrolithiasis. Thirteen EPs performed US, recorded the presence of hydronephrosis, and made an assessment of the likelihood of nephrolithiasis. All patients underwent i.v. pyelography (IVP) or unenhanced helical computed tomography (CT). There were 126 patients in the study: 84 underwent IVP; 42 underwent helical CT. Test characteristics of bedside US for detecting hydronephrosis were: sensitivity 72%, specificity 73%, positive predictive value (PPV) 85%, negative predictive value (NPV) 54%, accuracy 72%. The PPV and NPV for the ability of the EP to predict nephrolithiasis after performing US were 86% and 75%, respectively. We conclude that bedside US performed by EPs may be used to detect hydronephrosis and help predict the presence of nephrolithiasis.     

Three-dimensional sonographic morphologic assessment of adnexal masses: a reproducibility study.

OBJECTIVE: The purpose of this study was to assess the reproducibility of 3-dimensional (3D) sonography for classifying adnexal masses. METHODS: Eighty-two consecutive women with the diagnosis of an adnexal mass on 2-dimensional transvaginal sonography were reevaluated by 3D sonography, and 3D volume data from each mass were stored. Two different examiners (6 years and 1 year of experience in 3D sonography, respectively) reviewed 3D sonograms 1 month after the last patient was recruited and then 1 week later again. Masses had to be classified as benign or malignant. Criteria suggestive of malignancy were the presence of a thick wall, gross papillary projections, solid areas, and solid echogenicity. A definitive histologic diagnosis was obtained in every case. Intraobserver and interobserver agreement was estimated by calculating the Cohen kappa index. RESULTS: Twenty-seven (33%) tumors were malignant, and 55 (67%) were benign. Intraobserver agreement for both examiners was good (kappa = 0.78 and 0.72, respectively). Interobserver agreement was also good (kappa = 0.70). CONCLUSIONS: Three-dimensional sonography is a reproducible technique for morphologic assessment of adnexal masses.     

Performance of the RACE Score for the Prehospital Identification of Large Vessel Occlusion Stroke in a Suburban/Rural EMS Service

Introduction: Emergency Medical Services (EMS) providers may identify and preferentially transport patients experiencing large vessel occlusion (LVO) stroke to appropriate treatment centers. The Rapid Arterial oCclusion Evaluation (RACE) scale was created for prehospital LVO detection, yet few studies have evaluated its function in real-world EMS settings. Our objective was to assess the prehospital performance of the RACE scale for detecting LVO stroke following implementation at a large suburban/rural agency in the United States. Methods: In this retrospective analysis, all 9-1-1 patients with an EMS provider primary or secondary impression of stroke treated by the agency between June 1, 2016 and November 1, 2017 were eligible for inclusion. Patient data were abstracted using a standardized form completed by receiving hospitals. Performance for LVO detection at each RACE cutoff value was evaluated using sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). A receiver operating characteristic (ROC) curve was used to evaluate the discrimination of the RACE scale overall. A secondary analysis of RACE for patients experiencing strokes best treated at comprehensive stroke centers (LVO and intracerebral hemorrhage [ICH]) was conducted. Results: There were 440 patients with a documented RACE score and hospital outcome data included in the analysis. About half (51%, n?=?220) were female and the median age was 70 years (IQR: 59–81). Last known well time was under 4.5?hours for 76% of patients (n?=?261). Over half (61%, n = 269) had a hospital discharge diagnosis of stroke and 64/440 (15%) were classified as LVO. The ROC curve demonstrated adequate discrimination with a c-statistic of 0.72. Performance for identifying LVO in the prehospital setting was greatest for RACE scores ≥5 with a sensitivity of 66% and specificity of 72%, PPV of 29%, and NPV of 93%. A RACE score ≥5 for both LVO and ICH demonstrated sensitivity: 63%, specificity: 77%, PPV: 47% and NPV: 86%. Conclusion: The RACE scale demonstrated acceptable discrimination, yet the sensitivity and positive predictive value were lower in this cohort of EMS professionals in the United States than in the original validation study conducted in Spain. Further work is needed to determine the optimal prehospital screening tool for identification of LVO.     

经阴道彩色多普勒超声术前判断子宫内膜癌肌层浸润程度

目的探讨经阴道彩色多普勒超声(TVCDS)术前判断子宫内膜癌肌层浸润程度的准确性及其临床应用价值。方法对58冽子宫内膜癌患者术前行TVCDS检查，根据二：维图像特点和病灶内部及周围肌层的彩色血流情况，判断其肌层浸润程度，与手术病理结果作对比研究。结果TVCDS术前判断子宫内膜癌肌层浸润总的准确率为87．9％；无肌层浸润和浅肌层浸润的准确率分别为92.3％和85．2％；深肌层浸润的准确率为88．9％，其敏感性为84．2％，特异性：勾94．9％。结论TVCDS能较准确地判断子宫内膜癌肌层浸润程度，可作为术前判断子宫内膜癌肌层浸润程度的首选影像学检查方法，具有广泛的临床应用价值。     

Role of sonographic examination in traumatic knee internal derangement

OBJECTIVES: To define the accuracy (compared with magnetic resonance imaging [MRI]) of sonographic examination in detecting knee effusion and to determine whether the presence of knee effusions in patients with traumatic knee injury can predict knee internal derangement as assessed by MRI. DESIGN: Prospective study. SETTING: Hospital rehabilitation department. PARTICIPANTS: Thirty patients (19 men, 11 women) with traumatic knee injury were recruited. Subjects received sonographic examination and MRI on the same day. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: The presence or absence of knee effusion was assessed by sonographic examination. MRI was used as criterion standard to evaluate whether the presence of knee effusion and internal derangement, which included tear of anterior and posterior cruciate ligaments, as well as meniscus tear. RESULTS: The sensitivity of sonographic examination for detecting knee effusion was 79.1%, and specificity was 50%. The positive-predictive value (PPV) was 86.3% and negative-predictive value (NPV) was 37.5%. The PPV of sonographic effusion to internal derangement was 90.9%, and the NPV was 37.5%. CONCLUSIONS: Sonographic examination can accurately detect effusion of the knee. The detection of knee effusion in patients with traumatic knee injury by sonographic examination is highly indicative of internal knee derangement.     

Detection and characterization of perianal inflammatory disease: accuracy of transperineal combined gray scale and color Doppler sonography.

OBJECTIVE: To evaluate the accuracy of transperineal gray scale and color Doppler sonography for the detection and characterization of perianal inflammatory disease with surgical correlation. METHODS: Eighty-seven patients with suspected perianal inflammatory disorders underwent transperineal gray scale and color Doppler sonography with a linear 4- to 7-MHz transducer that was used to scan the entire perianal region for the detection of suspected inflammatory disorders. Each detected inflammatory disorder was evaluated to determine its morphologic characteristics and extent. Color Doppler sonography was applied to assess the presence of increased vascularity in the perianal region. In comparison with surgical findings, the diagnostic performance of transperineal sonography was assessed by means of receiver operating characteristic analysis for lesion detection and the Spearman rho test for lesion characterization. Logistic regression analysis was used to assess whether increased perineal vascularity was a predictive factor of perianal inflammatory disease. RESULTS: Seventy-seven perianal inflammatory disorders were confirmed in 62 patients. Gray scale sonography achieved a significantly good performance in the detection (area under the curve = 0.86; P < .001) and characterization (r = 0.65; P < .001) of perianal inflammatory disease. For the detection of perianal fistulas and abscesses, sensitivity was 100% for both, and specificity was 100% and 94%, respectively. With the use of color Doppler sonography, the diagnostic confidence increased slightly (area under the curve = 0.89) but significantly (P = .002). Logistic regression analysis identified hypervascularity at the periphery of a perianal lesion as a significant independent predictor of an inflammatory disease. CONCLUSIONS: Combined gray scale and color Doppler sonography enables a high detectability rate and comprehensive characterization of perianal abscesses and fistulas.     

Effects of altitude on spleen volume: sonographic assessment

PURPOSE: To use sonography to determine changes that may arise in splenic volume in humans from regions of lower altitude who begin to live in regions of higher altitude. MATERIALS AND METHODS: The study was conducted in the Turkish province of A?ri, at an altitude of 1750 m and included 108 healthy, nonsmoking, disease-free volunteers who had moved from regions at an altitude lower than 500 m. Length, width, and thickness of the spleen were measured using sonography. Splenic volume was calculated using the following standard ellipsoid formula: length x width x thickness x 0.523. Sonographic assessments were repeated at 3 and 6 months along with other blood tests, including hemoglobin, hematocrit, and platelet levels. RESULTS: The mean +/- SD splenic volume was 299 +/- 97 cm(3) (range, 116-574 cm(3)). At 3 and 6 months, the splenic volumes decreased significantly compared to their initial values (p < 0.05). An increase in hemoglobin, hematocrit, and platelet count was observed in all subjects. CONCLUSION: Our data show that splenic volume in healthy individuals who begins to live at high altitudes decreases gradually.     

Evaluation of extremity trauma with sonography.

OBJECTIVE: To report on the use of bedside sonography in the diagnosis and treatment of penetrating extremity trauma. METHODS: Sonography was performed in the emergency department of a level 1 trauma center with both curved and linear array transducers. RESULTS: In both cases, foreign bodies and fractures resulting from gunshot wounds to the extremities were found. In addition, intra-abdominal and thoracic injuries were evaluated for using sonography. CONCLUSIONS: The increasing mobility and portability of sonography has led to its increasing use at the patient' bedside to diagnose a variety of conditions. It provides potential immediate diagnosis and has the flexibility for evaluating a multitude of injuries normally requiring several different imaging technologies. In circumstances in which conventional radiography is unavailable, such as at trauma scenes, mass casualty situations, or at the bedside with unstable patients, sonography can provide unique and essential information about these patients.