共查询到20条相似文献,搜索用时 0 毫秒
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Se A. Lee Eek-Sung Lee Bo Gyung Kim Tae-Kyeong Lee Ki-Bum Sung Kyurin Hwang 《Acta oto-laryngologica》2019,139(6):511-516
Background: Acute vestibular syndrome (AVS) is characterized by the rapid onset of vertigo, nausea, vomiting and gait unsteadiness, which lasts for days.Aims/objectives: We report cases as acute vestibular asymmetry disorder (AVAD), with presentations that mimic vestibular neuritis (VN) but without central lesions.Materials and methods: We retrospectively reviewed records of patients presenting with acute spontaneous vertigo lasting more than 24?h from January 2011 to June 2016. Among 341 patients, five showed different findings that did not indicate either VN or stroke. We analyzed the clinical features and vestibular assessments of these patients.Results: All five patients showed spontaneous nystagmus continuing for several days. However, head impulse tests (HITs) did not reveal a corrective saccade. Brain magnetic resonance imaging showed no abnormal lesions. The bithermal caloric test revealed directional preponderance without canal paresis. Finally, the slow harmonic test of the rotatory chair revealed unilateral high gain and phase within the normal range, but a significantly asymmetric response was observed. No patients showed recurrence during follow-up.Conclusions and significance: Our study suggests that a normal HIT in AVS is not always a dangerous sign indicating an acute stroke. From our observations, we propose that AVAD would be a new disease entity within AVS. 相似文献
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Periodic alternating nystagmus (PAN) is a spontaneous horizontal nystagmus that reverses direction periodically. PAN has been reported in acquired and congenital forms. The lesion site of the acquired form of PAN has been attributed to the caudal brainstem or cerebellum. We report an extremely rare case (a 59-year-old woman) with bilateral Meniere's disease, who presented PAN. PAN in this patient was suppressed in the light. This patient had smooth pursuit and normal optokinetic nystagmus, although patients with PAN usually show saccadic pursuit and impaired optokinetic nystagmus. These findings were different features from those of the central or congenital form of PAN. It should be kept in mind that peripheral vestibular disorders such as Meniere's disease could produce PAN. 相似文献
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Objective
Vestibular neurectomy is considered the reference treatment of incapacitating vertigo accompanying Meniere disease, with an efficiency rate of 85–95% in most literature reports.The aim of this study is to evaluate if vestibular neurectomy can provide a complete vestibular deafferentation by investigating complete vestibular function after surgery.Methods
Prospective study. Twenty-four patients suffering from incapacitated Meniere vertigo crisis beneficiated from a vestibular neurectomy by retrosigmoid approach. The average time between surgery and vestibular evaluation was 1 year. We performed (i) kinetic test, (ii) caloric test and (iii) vibration-induced nystagmus (VIN) at 30, 60 and 100 Hz under videonystagmography recording, (iv) vestibular evoked myogenic potentials (VEMP), (v) video head impulsed test (VHIT) for each semicircular canals and (vi) an evaluation of visual vertical and horizontal subjective (VVS and HVS).Results
On clinical evaluation, all the patients except one had never experienced any recurrence of vertigo crisis after surgery. The 24 patients would definitely undergo the surgery again. On vestibular evaluation, on the operated side, all patients showed a total areflexia at caloric test; 23 patients had no VEMP response; 23 patients had abolished canals response to VHIT. All the patients had VVS and HVS deviated towards the operated side; 23 patients had a high velocity VIN from 30 to 60 Hz.Conclusion
This study proves that vestibular neurectomy can provide a complete vestibular deafferentation. We discuss this vestibular evaluation protocol and the main difficulties encounter during surgery, which could lead to partial nerve section and partial relief, and explain residual vestibular function after vestibular neurectomy. 相似文献7.
《Acta oto-laryngologica》2012,132(7):824-827
Periodic alternating nystagmus (PAN) is a spontaneous horizontal nystagmus that reverses direction periodically. PAN has been reported in acquired and congenital forms. The lesion site of the acquired form of PAN has been attributed to the caudal brainstem or cerebellum. We report an extremely rare case (a 59-year-old woman) with bilateral Meniere's disease, who presented PAN. PAN in this patient was suppressed in the light. This patient had smooth pursuit and normal optokinetic nystagmus, although patients with PAN usually show saccadic pursuit and impaired optokinetic nystagmus. These findings were different features from those of the central or congenital form of PAN. It should be kept in mind that peripheral vestibular disorders such as Meniere's disease could produce PAN. 相似文献
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Mohyuddin A Vokurka EA Evans DG Ramsden RT Jackson A 《Clinical otolaryngology and allied sciences》2003,28(2):85-90
We have assessed the clinical growth index as an indicator of tumour growth rate in 50 patients with a vestibular schwannoma. Clinical growth index was calculated by measuring the length of history and dividing it by the maximum tumour diameter. Total tumour volumes were also measured from all MRI examinations and an effective tumour volume doubling time was calculated. Radiological growth measurements demonstrated involution in 10/50 patients. The median volume doubling time was 1.65 years (range 20.9-46.3 months, skewness 1.72 years). The median clinical growth index was 0.030 cm per month (range 0-0.270 cm per month, skewness 2.398). There was no significant correlation between volume doubling time and clinical growth index. Identification of rapidly growing tumours with clinical growth index >0.025 cm/month had a positive predictive value of 61%, negative predictive value of 48%, false-positive rate of 30% and false-negative rate of 52%. In conclusion, we have shown that the growth rate of vestibular schwannoma is not related to the clinical growth index and we recommend that this measure should be abandoned in the clinical management of patients where conservative management regimes are being considered. 相似文献
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A. Mohyuddin E.A. Vokurka D.G.R. Evans R.T. Ramsden A. Jackson 《Clinical otolaryngology》2003,28(2):85-90
Is clinical growth index a reliable predictor of tumour growth in vestibular schwannomas? We have assessed the clinical growth index as an indicator of tumour growth rate in 50 patients with a vestibular schwannoma. Clinical growth index was calculated by measuring the length of history and dividing it by the maximum tumour diameter. Total tumour volumes were also measured from all MRI examinations and an effective tumour volume doubling time was calculated. Radiological growth measurements demonstrated involution in 10/50 patients. The median volume doubling time was 1.65 years (range 20.9‐46.3 months, skewness 1.72 years). The median clinical growth index was 0.030 cm per month (range 0‐0.270 cm per month, skewness 2.398). There was no significant correlation between volume doubling time and clinical growth index. Identification of rapidly growing tumours with clinical growth index >0.025 cm/month had a positive predictive value of 61%, negative predictive value of 48%, false‐positive rate of 30% and false‐negative rate of 52%. In conclusion, we have shown that the growth rate of vestibular schwannoma is not related to the clinical growth index and we recommend that this measure should be abandoned in the clinical management of patients where conservative management regimes are being considered. 相似文献
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ObjectiveThe goal of this study is to analyze the clinical view of patients with direction-fixed positional nystagmus (DFPN) following head-roll maneuver.MethodsSixty patients with DFPN were reviewed retrospectively. Patients were categorized into 3 groups according to the direction of nystagmus based on rotation side. Associated problems were documented, and cumulative data were compared between groups. One-way analysis of variance (ANOVA test) was used for statistical analysis (P < 0.05).ResultsThirty-three patients (55%) had stronger nystagmus beating towards the direction of head-roll (Group-A). Three patients developed geotropic LC-BPPV. Fourteen patients had inner ear disease. Sixteen patients (27%) had stronger nystagmus beating against the direction of head roll (Group-B). Nine patients had inner ear disease. None of the patients tested with head-shaking had change of direction of nystagmus. Eleven patients (18%) had DFPN with equal velocity during right or left head-roll maneuver (Group-C). Of those, nine patients had inner ear disease. None of the patients had change of direction of nystagmus. Comparison of the incidence of associated problems (migraine, vestibular neuronitis, Meniere’s disease etc.) in each group was not statistically significant (P˃0.05).ConclusionPatients with DFPN should be followed for a possibility of vestibular pathology since vestibular problem was documented for more than half of the patients in the follow-up. On the other hand, DFPN could be related with a temporary reason (thermal, physical or drug effect etc.) in some patients who do not exhibit any associated disease. Head-shaking testing is recommended to expose the lateral canal BPPV. But the incidence is low. 相似文献
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Ertugrul Ozlem Mutlu Ahmet Zindanci ilkin Cam Osman Halit Ozluoglu Levent 《European archives of oto-rhino-laryngology》2019,276(6):1625-1632
European Archives of Oto-Rhino-Laryngology - Behçet’s disease (BD) is a vasculitis that involves all small vessels and influences the multiple systems of the human body. This study aimed... 相似文献
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Gupta AK Bansal S Gupta A Mathur N 《International journal of pediatric otorhinolaryngology》2006,70(4):603-608
OBJECTIVE: Comparison of characteristic features, radiology, management and recurrence pattern of fungal sinusitis between children and adults. METHODS: A prospective study conducted in the department of Otorhinolaryngology, Head and Neck Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh in which all the cases presenting with the features of allergic fungal sinusitis (AFS) between January 2000 and January 2005 were enrolled. These cases were divided into two groups, group 1 comprised of cases with age less than 15 years and group 2 with age more than 15 years. Detailed history, physical examination and nasal endoscopic examination and computed tomography (CT) scan of the paranasal sinuses was done in all the cases. The cases with prior history of sinonasal surgery were excluded from the study. All patients refractory to medical management were subjected to endoscopic sinus surgery. All the cases were followed up for a period ranging from 6 to 39 months to see for the recurrence. The data of both the groups was analysed statistically using chi square test. RESULTS: The study population comprised of 200 cases, with 68 cases in group 1 and 132 cases in group 2. The most common symptom in both the groups was presence of nasal obstruction. The children had higher incidence of having unilateral disease (46 out of 68) compared with adults, where it was 38 out of 132. The bony erosion was seen more often in group 1. Surgery was done endoscopically in all the cases. The intra orbital or intra cranial extension was seen in 58 cases of group 1 and 47 cases of group 2 (p<0.001). Recurrence was seen in 18 (15 with intraorbital and 3 with intracranial extension) cases in group 1 and 13 cases (11 with intraorbital and 2 with intracranial extension) in group 2 (p<0.005). CONCLUSION: In our study, we found a higher incidence of facial deformities, proptosis, intraorbital/intracranial extension and a higher rate of recurrence in group 1, therefore, suggesting a more aggressive nature of AFS in children than adults mandating an early diagnosis, proper management and regular follow up in these cases. 相似文献
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Delaroche M Gavilan-Cellié I Maurice-Tison S Kpozehouen A Dauman R 《International journal of pediatric otorhinolaryngology》2011,75(12):1502-1509
Background and goal
When carried out in addition to objective tests, behavioral audiometry performed in children with the so-called “Delaroche protocol” [IJORL 68 (2004) 1233-1243] enables to determine hearing thresholds by air and bone conduction over the whole auditory frequency range. In the present report, seventy-three hearing-impaired infants with different levels of motor and cognitive development were tested behaviorally before 6 months of age. Reliability of these early determined behavioral thresholds was then after analyzed using: (a) cross-sectional study, and (b) longitudinal study.Methods
Cross-sectional study compared click-evoked ABR thresholds in the better ear with binaural high-frequency hearing thresholds. In longitudinal study, early measured binaural hearing thresholds from 500 through 4000 Hz were reassessed at 18 months.Results
In 13% of babies behavioral testing was not fully completed by 6 months of age. Nevertheless, both cross-sectional and longitudinal studies yielded intraclass correlation coefficients above 0.80, suggesting that behavioral testing is applicable to this very young population.Conclusions
Assessment of hearing after newborn screening should not be restricted to objective tests before 5½ months. It should also include bone- and air-conduction behavioral tests adjusted to developmental stage and performed in presence of parents. 相似文献18.
Does vestibular damage cause cognitive dysfunction in humans? 总被引:2,自引:0,他引:2
Smith PF Zheng Y Horii A Darlington CL 《Journal of vestibular research : equilibrium & orientation》2005,15(1):1-9
For more than a decade, evidence from animal studies has suggested that damage to the vestibular system leads to deficits in spatial navigation which are indicative of impaired spatial learning and memory. More recently, direct evidence has emerged to demonstrate that humans with vestibular disorders exhibit a range of cognitive deficits that are not just spatial in nature, but also include non-spatial functions such as object recognition memory. Vestibular dysfunction has been shown to adversely affect attentional processes and increased attentional demands can worsen the postural sway associated with vestibular disorders. Recent MRI studies also show that humans with bilateral vestibular damage undergo atrophy of the hippocampus which correlates with their degree of impairment on spatial memory tasks. These results are consistent with those from animal studies and, together, suggest that humans with vestibular disorders are likely to experience cognitive dysfunction which is not necessarily related to any particular episode of vertigo or dizziness, and therefore may occur even in patients who are otherwise well compensated. These findings may be related to the observation that patients with vestibular deficits experience a high incidence of depression and anxiety disorders. 相似文献
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OBJECTIVE: To determine changes in vestibular function following intratympanic gentamicin (ITG) treatment for Meniere's disease and to correlate changes with the need for further treatment. STUDY DESIGN: Prospective case series. PATIENTS: One hundred and three patients with disabling unilateral Meniere's disease who had failed a minimum of 6 months medical treatment. MAIN OUTCOME MEASURES: Vestibular function was measured by electronystagmography (ENG) caloric testing before and serially following treatment. Caloric responses were classified as normal (excitability difference [ED] < 25%), bithermal response (ED > or = 25%), positive response to ice water only, and absent ice water response. RESULTS: Twenty-one percent of patients had a bithermal caloric response, 62% had an absent ice water response, and 17% had an ice water response only 1 month following treatment. Mean follow-up was 27.3 months (range = 1-106 months). Eighty-four patients had one treatment course only. Fourteen patients required a further course of treatment due to recurrence of vertigo; 38% of these had recovery of caloric function. Significantly more patients with normal caloric function prior to initial treatment required further treatment compared to those with initial reduced caloric function (p < .05). Patients rendered absent ice water responsive were significantly less likely to require further treatment than those with a persistent caloric response (p < .0001). CONCLUSION: An absent ice water response is highly predictive of adequate vertigo control. Regimens of ITG that aim to completely ablate vestibular function are recommended. 相似文献