3477例耻骨后前列腺癌根治术患者性功能、控尿及并发症分析

前列腺癌根治术是治疗早期前列腺癌最有效的方法，但由于惧怕术后并发症，许多患者放弃了手术机会。本文对1983年5月至2003年2月3477例连续进行的保留神经的前列腺癌根治术患者的勃起功能、控尿情况和术后并发症进行了分析。所有手术均由同一位外科医生完成，术中视情况保留单侧或双侧神经。     

腹腔镜前列腺癌根治术中膀胱颈完整保留对术后尿控及性功能的影响

目目的的::探讨腹腔镜前列腺癌根治术中膀胱颈完整保留对术后尿控功能及性功能的影响.方法:选取西安交通大学第二附属医院2015年3月-2019年3月期间收治的148例腹腔镜前列腺癌根治术患者作为研究对象,按照随机数字表法将其分为对照组(74例)与观察组(74例).对照组不保留膀胱颈,观察组完整保留膀胱颈.比较两组手术指标...     

保留尿道括约肌功能对腹腔镜前列腺癌根治术后尿控的影响

目的:探讨保留尿道括约肌功能对腹腔镜前列腺癌根治术后尿控的影响。方法:选取2013年5月至2015年8月收治的行腹腔镜前列腺癌根治术的80例前列腺癌患者作为研究对象,依据是否保留尿道括约肌功能分为对照组(未保留)及研究组(保留),每组40例,对比两组患者术后3个月的尿控情况。结果:两组患者尿控分级差异有统计学意义(P0.05);术后两组患者前列腺体积、前列腺特异性抗原、ICI-Q-SF评分、总并发症发生率差异有统计学意义(P0.05)。结论:保留尿道括约肌功能可显著提高腹腔镜前列腺癌根治术后的尿控效果,改善前列腺体积、前列腺特异性抗原、ICI-Q-SF评分等指标,降低术后并发症发生率,有助于尿控目标的实现,提高了患者的生活质量,具有重要的应用价值。     

前列腺癌根治术后早期尿控功能恢复相关影响因素分析

目的 探讨前列腺癌(PCa)根治术后尿控功能恢复的相关因素.方法 回顾性分析2016-10—2019-10在郑州大学第一附属医院行PCa根治术的390例PCa患者的临床资料.根据术后第1、3个月的尿控功能恢复情况分为尿控组和尿失禁组.比较2组患者的年龄、体质量指数(BMI)、吸烟、饮酒、手术方式;是否保留膀胱颈、神经血...     

提高前列腺癌根治术后尿控能力的临床研究

目的：探讨提高前列腺癌根治术后尿控能力的方法。方法：对15例前列腺癌采用保留尿道膜部括约肌及前列腺侧旁神经血管束的方法进行前列腺癌根治术。结果：经6—45个月随访，15例患者排尿通畅，无肿瘤复发，除1例有轻度尿失禁外，余14例6个月内均恢复尿控能力。结论：保留尿道膜部括约肌及前列腺侧旁神经血管束的方法能减低前列腺癌根治术后尿失禁。     

系统评价机器人辅助腹腔镜与单纯腹腔镜前列腺癌根治术后的控尿功能

目的:评价机器人辅助前列腺癌根治术(robot-assisted laparoscopic prostatectomy,RALP)与单纯腹腔镜前列腺癌根治术(pure laparoscopic radical prostatecomy,LRP)的术后控尿功能。方法:检索PubMed、Web of Science、Cochrane图书馆、CNKI、维普数据库及万方数据库关于RALP和LRP治疗局限性前列腺癌的比较性研究文献,按Cochrane操作员手册筛选文献、提取资料并评价质量后,采用RevMan5.2版本软件进行数据处理分析。结果:系统评价纳入2篇随机对照试验,7篇非随机对照试验,共1 950例患者,其中RALP治疗1 098例,LRP治疗852例。RALP相比LRP术后控尿率,1个月比值比(odds ratio,OR)=2.28,95%可信区间(confidence interval,CI)为(1.68,3.08),3个月OR=1.51,95%CI为(1.21,1.88),6个月OR=1.97,95%CI为(1.44,2.70),12个月OR=1.53,95%CI为(1.11,2.11),两者术后控尿功能差异有统计学意义(P0.05)。结论:在治疗局限性前列腺癌方面,RALP可能术后控尿功能更优。     

负压勃起装置治疗前列腺癌根治术后的勃起功能障碍

目的:探讨负压勃起装置(VED)治疗前列腺癌根治术(RP)后勃起功能障碍(ED)的有效性和安全性。方法:开放性RP术后ED患者6例,3例于术后3个月内(A组),3例于术后12个月以上(B组)分别进行VED康复治疗,比较两组在VED治疗前,治疗后3个月和6个月的IIEF-5评分的差异,治疗6个月后的阴茎长度和周径变化的差异。评价VED应用的安全性,以及患者和性伴侣的满意度。结果:6例患者VED治疗后3个月和6个月的IIEF-5平均评分均较治疗前提高(P<0.05)。A组患者VED治疗后3个月IIEF-5评分(8.7±0.6)分,治疗后6个月IIEF-5评分(13.0±1.0)分,均高于B组患者[(6.7±0.6)分;(8.3±1.5)分](P<0.05)。VED治疗后6个月,A组患者阴茎长度缩短(0.4±0.1)cm,周径缩短(0.2±0.1)cm,B组患者阴茎长度缩短(1.7±0.4)cm,周径缩短(0.9±0.3)cm,两组相比均有显著差异(P<0.05)。VED治疗后6个月的患者及性伴侣性生活满意率分别为83.3%和50.0%。VED治疗期间,1例患者诉阴茎皮肤发暗,2例诉性交僵硬麻木感,其余无明显不良反应。结论:RP术后ED患者早期进行VED康复治疗,能显著改善勃起功能,减少阴茎萎缩。     

盆筋膜腱弓重建对腹腔镜前列腺癌根治术后尿控的影响

目的:评估盆筋膜腱弓重建对腹腔镜前列腺癌根治术后尿控的影响。方法:回顾分析2012年1月至2014年12月42例局限性前列腺癌患者的临床资料,其中20例行盆筋膜腱弓重建腹腔镜前列腺癌根治术(重建组),22例行常规腹腔镜前列腺癌根治术(常规组),对比分析两组患者术后拔除尿管后第1天及术后1个月、3个月、6个月、12个月的尿控情况,以不使用尿垫作为完全尿控标准。结果:两组患者术前年龄、体重指数、前列腺体积、前列腺特异性抗原、Gleason评分差异均无统计学意义(P0.05)。常规组拔除尿管后第1天及术后1个月、3个月、6个月、12个月尿控率分别为4.55%(1/22)、18.18%(4/22)、36.36%(8/22)、68.18%(15/22)、81.82%(18/22);重建组分别为5.00%(1/20)、25.00%(5/20)、70.00%(14/20)、85.00%(17/20)、90.00%(18/20);重建组术后3个月尿控率高于常规组(P0.05),其余时间两组差异无统计学意义(P0.05)。结论:盆筋膜腱弓重建技术对于腹腔镜前列腺癌术后早期(3个月内)的尿控恢复可能有帮助,对远期尿控效果改善不明显。     

Pelvic floor muscle training improves sexual function of women with stress urinary incontinence

The aim of this study was to assess the effect of a program of supervised pelvic floor muscle training (PFMT) on sexual function, in a group of women with urodynamically diagnosed stress urinary incontinence (SUI), using a validated questionnaire. Incontinence episodes frequency and continence pads used per week were measured before and after treatment using a 7-day bladder diary. Improvements in sexual function were assessed using the Female Sexual Function Index (FSFI). Seventy women completed the 12-month program of supervised PFMT successfully. At the end of the study, incontinence episode frequency decreased by 38.1%, and patients required 39% less pads per week. All domains of the FSFI were also significantly improved with median total FSFI scores increasing from 20.3 to 26.8. This is one of the few studies to quantify, using a validated questionnaire, the improvement in sexual function of women with SUI, undergoing successfully a 12-month supervised PFMT program.     

The effect of pelvic floor training on sexual function of treated patients

The aim of this study was to determine the effects of improvements in urinary incontinence resulting from pelvic floor rehabilitation on the sexual function of patients. The study involved 42 clinic patients who received pelvic floor rehabilitation treatment. Their sexual histories were obtained through face-to-face interviews. Pelvic muscle strength was measured with a perineometer. Improvement in incontinence was measured with the pad test. Seventeen women reported decreased sexual desire before the treatment; 5 of these indicated improvement after treatment. Nine of 17 women who experienced dyspareunia prior to treatment reported an improvement afterwards, and four women reported complete relief from pain. Five of 15 women who complained of difficulty in reaching climax before the treatment experienced improvement in this area. In conclusion, an improvement in sexual desire, performance during coitus and achievement of orgasm were observed in women who received pelvic floor muscle rehabilitation. No change was seen in the arousal and resolution stages of sexual activity.Abbreviation FES Functional electrical stimulationEditorial Comment: Previous studies suggest that the prevalence of sexual dysfunction is high amongst women with urinary incontinence. Some data exist about the effect of surgical treatment of urinary incontinence and its effect on sexual function. Data also exist that women with sexual dysfunction due to painful conditions improve with pelvic floor therapy. It could be expected that women with urinary incontinence and sexual dysfunction show better overall improvement of both conditions when treated with pelvic floor therapy rather than with surgery. Patients in this study showed improvement in urinary incontinence with pelvic floor therapy. They also had a marked decrease in dyspareunia. Overall, there was improvement in sexual function, particularly an increase in desire. Unfortunately, the study does not address whether this improvement appears to be related to a decrease in incontinence, a decrease in pain with intercourse or an additive effect.     

Evaluation of early pelvic floor physiotherapy on the duration and degree of urinary incontinence after radical retropubic prostatectomy in a non-teaching hospital

The objective of this study was to study the effect of early pelvic floor re-education on the degree and duration of incontinence and to evaluate the results of radical retropubic prostatectomy (RRP) performed in a non-teaching hospital. This is a non-randomised study. From March 2000 to November 2003, 57 consecutive men, who underwent RRP for localized prostate cancer, participated in a pelvic floor re-educating program. Continence was defined as a loss of no more than 2-g urine on the 24-h pad test and no use of pads. The 24-h pad test was performed once in every 4 weeks until the patient indicated that he was continent. Diurnal and nocturnal continence was achieved after 1, 2, 3, 6 and 12 months post catheter removal in 40, 49, 70, 86 and 88% of all men, respectively. Comparison of our results with current literature suggest that the time period towards continence after a RRP can be shortened relevantly if pelvic floor re-education is started directly after catheter removal.     

加速康复外科理念下针刺治疗腹腔镜下前列腺癌根治术后尿失禁的疗效观察

目的基于加速康复外科理念下观察针刺治疗腹腔镜下前列腺癌根治术后尿失禁的临床疗效。方法将2018年1月至2019年11月青岛市市立医院收治的48例腹腔镜下前列腺癌根治术后尿失禁患者,分为试验组和对照组(每组24例),试验组采用针刺联合盆底肌训练疗法,对照组采用盆底肌训练法。观察两组患者在治疗前后控尿的变化。结果两组组内治疗前后相比1 h尿垫试验漏尿量(g)、ICIQ-SF评分、24 h尿失禁次数均有改善;试验组治疗后各项观察指标均显著低于对照组,总有效率、治愈率均显著高于对照组;两组未见明显不良反应。结论针刺能够有效改善腹腔镜下前列腺癌根治术后患者尿失禁症状,促进尿控功能的恢复,符合加速外科康复理念,值得推广。     

Medium-term efficacy of pelvic floor muscle training for female urinary incontinence in daily practice

The purpose of this paper is to assess the efficacy of physiotherapy and quality of life in women treated for urinary incontinence by specialized physiotherapists in daily community-based practices. Three hundred and fifty-five women were treated in five physiotherapy practices between January 2000 and December 2004. After a minimum follow-up of 12 months, these women received a questionnaire at home. With the questionnaire, we collected demographic data, data on the efficacy of treatment, satisfaction with the result, and the Urogenital Distress Inventory, and Incontinence Impact Questionnaire. Additional information was derived from the medical files. One hundred and eighty-seven women responded. Fifty percent of women were satisfied with the result of physiotherapy. After a mean follow-up of 32 months, 123 out of 130 women (94.6%), who only had physiotherapy, recorded to experience incontinence episodes daily to several times a week. Women who underwent additional incontinence surgery after insufficient physiotherapy recorded significantly less urinary incontinence symptoms and a better quality of life. Pelvic floor muscle training for urinary incontinence is effective in half of the women. If not successful, women seem to benefit significantly from incontinence surgery.     

Assessment of sexual function in women with pelvic floor dysfunction

Forty-seven women participated in a pilot study for a multi-centre randomized controlled trial of the effectiveness of pelvic floor muscle training (PFMT) for women with prolapse. Women with symptomatic stage I or II prolapse [measured by Pelvic Organ Prolapse Quantification (POP-Q)] were randomized to a 16-week physiotherapy intervention (PFMT and lifestyle advice; n = 23) or a control group receiving a lifestyle advice sheet (n = 24). Symptom severity and quality of life were measured via postal questionnaires. Blinded POP-Q was performed at baseline and follow-up. Intervention women had significantly greater improvement than controls in prolapse symptoms (mean score decrease 3.5 versus 0.1, p = 0.021), were significantly more likely to have an improved prolapse stage (45% versus 0%, p = 0.038) and were significantly more likely to say their prolapse was better (63% versus 24%, p = 0.012). The data support the feasibility of a substantive trial of PFMT for prolapse. A multi-centre trial is underway.     

电刺激联合盆底肌训练治疗女性压力性尿失禁合并特发性逼尿肌过度活动的疗效观察

目的 探讨电刺激联合全程指导盆底肌训练治疗女性压力性尿失禁(SUI)合并特发性逼尿肌过度活动(IDO)的疗效.方法选取经尿动力学检查证实为SUI合并IDO女性患者70例.平均年龄(40±7)岁.采用神经肌肉电刺激治疗仪电刺激,每次60 min,每周3次.联合盆底肌训练,每次30 min,每天2次,疗程12周.记录治疗前后患者排尿日记,填写国际尿失禁咨询委员会尿失禁问卷简表(ICI-Q-SF)和尿动力学测定,并随访3个月疗效.结果 50例(71%)完成全程治疗.其中尿失禁症状完全消失8例(16%),IDO消失10例(20%),漏尿点压测定无漏尿发生6例(12%).治疗后总排尿次数、总漏尿事件次数、ICI-Q-SF评分、最大逼尿肌不随意收缩压和持续时间分别为(28±5)次/72 h、(10±5)次/72 h、(10±3)、(18±8)cm H2O和(8±3)s,显著低于治疗前的(43±8)次/72 h、(20±6)次/72 h、(17±3),(27±9)cm H2O和(13±6)s(P<0.01);最大排尿量、正常尿意膀胱压测定容量、最大膀胱压测定容量、漏尿点压和最大尿道闭合压分别为(225±48)、(210±48)、(247±48)ml、(94±11)和(59±8)cm H2O,显著高于治疗前的(159±37)、(141±39)、(178±36)ml、(81±15)和(55±8)cm H2O,差异有统计学意义(P<0.01).治疗结束时和3个月后有效率为66%和60%,差异无统计学意义(P>0.05).结论 电刺激联合盆底肌训练是一种治疗女性SUI合并IDO的有效方法.     

The impact of pelvic organ prolapse on sexual function in women with urinary incontinence

The aim of the study is to evaluate the impact of pelvic organ prolapse (POP) on sexual function in women with urinary incontinence (UI). In this retrospective, case-cohort study, we reviewed the medical records of all women evaluated for UI between March and November 2003. All patients completed the short forms of the Urogenital Distress Inventory, Incontinence Impact Questionnaire, and Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire. Women with stage two or greater POP, as determined by the pelvic organ prolapse quantification (POPQ) system, were compared to women with stage 0 or 1 POP. Sixty-nine women with POP and 47 women without POP were included. Patient demographics did not differ between the two groups. Women with POP were significantly more likely to report absence of libido (53% versus 30%, P=0.02), lack of sexual excitement during intercourse (46% versus 27%, P=0.05), and that they rarely experienced orgasm during intercourse (49% versus 30%, P=0.05). In conclusion, women with POP in addition to UI are more likely to report decreased libido, decreased sexual excitement, and difficulty achieving orgasm during intercourse when compared to women with UI alone.     

阴道锥体训练联合生物反馈盆底肌治疗尿失禁老年人盆底肌康复研究现状

目的研究阴道锥体训练联合生物反馈盆底肌治疗尿失禁老年人的临床疗效及对盆底肌的影响。方法选取84例从2016年9月至2018年3月本院收治的尿失禁老年患者进行研究,以随机抽签法将其均分为联合组及对照组,每组42例。对照组予以常规盆底肌训练治疗,联合组则予以阴道锥体训练联合生物反馈盆底肌治疗。对比两组在临床疗效、治疗前后盆底肌力情况、治疗前后尿动力学参数指标水平以及生活质量变化情况等方面的差异。结果联合组与对照组在总有效率方面比较,前者高于后者(P<0.05)。治疗后联合组盆底肌力分级为Ⅳ级、Ⅴ级的人数占比相比对照组较高(P<0.05)。治疗后联合组与对照组在VLPP、PMUC水平方面比较,前者高于后者(P<0.05)。治疗后联合组与对照组I-QOL评分相比治疗前较高,且联合组相比对照组较高(P<0.05)。结论阴道锥体训练联合生物反馈盆底肌治疗老年尿失禁患者的疗效显著,有利于促进盆底肌力的恢复,且有效改善患者尿动力学参数,提高生活质量,具有较高的临床推广应用价值。     

盆底障碍性疾病盆底自主收缩肌肉力量研究

目的比较正常人和盆底障碍性疾病(PFD)患者的盆底肌肉功能。方法对2007年11月至2008年4月在本院就诊的压力性尿失禁(SUI)、盆腔器官脱垂(POP)、POP合并SUI患者以及健康对照组各10例,行阴道指诊、阴道挤压力检测盆底肌肉收缩力量进行评估。结果肛提肌肌肉指诊力量和阴道挤压力呈正相关(r=0.549,P<0.05)。对照组阴道指诊肌力等级为(4.1±0.8),阴道挤压压力为(38.4±21.1)mmH2O,15 s内可自主收缩肛提肌(6.0±1.2)次,收缩持续时间为(4.78±1.78)s。SUI组、POP组、SUI+POP组阴道指诊肌力等级分别为(2.6±0.7)(、3.2±1.2)和(3.0±1.4),均显著低于对照组(P<0.05);阴道内挤压压力分别为(20.2±11.1)、(13.8±10.3)、(20.0±10.4)mmH2O,均显著低于对照组(P<0.05)。SUI组15 s内可自主收缩肛提肌(3.6±1.0)次,显著少于对照组(P<0.05),收缩持续时间为(2.40±1.35)s,与对照组比较显著缩短(P<0.05)。结论肛提肌的阴道指诊的肌力测定,简单易行,可在临床广泛应用。PFD患者普遍存在肛提肌肉收缩力量减弱。SUI患者收缩速率慢、收缩持续时间短,不能对抗连续的腹压增高可能是SUI的发病机制。