逆行性A型主动脉夹层腔内隔绝治疗效果观察

目的 观察逆行性A型主动脉夹层的腔内隔绝治疗效果，探讨逆行性A型主动脉夹层腔内隔绝治疗的策略。方法 选取湖南中医药大学第一附属医院2016年10月至2020年11月近端内膜破口位于降主动脉的逆行性A型主动脉夹层患者19例，行主动脉覆膜支架植入术，并于术后1周、3个月、半年、1年随访观察治疗效果。结果 全组随访无一例患者死亡，2例患者支架近端主动脉弓部出现局限性溃疡，2例出现升主动脉夹层，1例支架远端出现夹层，其余14例患者均恢复良好，无相关并发症。结论 近端内膜破口位于降主动脉的逆行性A型主动脉夹层患者，经保守治疗后择期行腔内隔绝手术的治疗策略近中期效果理想。     

胸主动脉腔内修复术治疗急性复杂性Stanford B型主动脉夹层

【摘要】急性Stanford B型主动脉夹层（ATBAD）是严重威胁患者生命的急危重症。近年来,腔内修复治疗(EVAR)急性B型主动脉夹层已得到广泛应用。然而,由于胸腹主动脉特殊的解剖结构、疾病本身的复杂性、术后支架相关并发症的发生及修复技术的多样性,对于急性复杂性Stanford B型主动脉夹层（cATBAD）,选择外科手术还是腔内修复治疗、如何更科学地选择支架及应用相关技术进行腔内修复治疗,仍是困扰许多介入医生的问题。本文就cATBAD的腔内修复治疗作一综述,以期提高对腔内修复治疗本病的认识。     

急性期Stanford B型主动脉夹层腔内治疗研究进展

随着胸主动脉腔内修复术（TEVAR）的广泛应用及迅速发展,腔内治疗已成为了Stanford B型主动脉夹层的一线治疗方法。腔内治疗主动脉夹层的预后除了依赖于术前个体化方案的制定和术中操作者的经验,更依赖于手术指征及时机的掌握。对于急性期复杂性B型夹层,提倡在药物治疗的基础上早期行TEVAR手术;对于急性期非复杂性B型夹层是否可行TEVAR手术仍存在争议。文章主要就急性期B型主动脉夹层行腔内治疗的研究进展进行综述。     

Stanford B型主动脉夹层腔内治疗围术期护理规范专家共识北大核心CSCD

形成《Stanford B型主动脉夹层腔内治疗围术期护理规范专家共识》(以下简称《共识》),规范Stanford B型主动脉夹层患者腔内治疗围术期的护理。通过检索国内外主动脉夹层诊治护理相关证据,形成《共识》初稿。邀请50位血管外科及相关领域医护专家进行函询,根据专家建议进行分析、修改及完善,形成《共识》终稿。《共识》内容包括:Stanford B型主动脉夹层最新解剖定位、腔内治疗方式及适应证、术前及术后护理四方面。本《共识》实用性强,可为Stanford B型主动脉夹层腔内治疗围术期护理提供指导依据。     

血管腔内治疗B型胸主动脉夹层伴A型壁内血肿3例北大核心CSCD

目的探讨胸主动脉腔内修复术(TEVAR)治疗Standford B型夹层伴A型壁内血肿(MH)的安全性及有效性。方法 2015年10月至2017年1月共收治3例B型夹层伴A型MH患者,入院后稳定血压、心率,对症保守治疗14 d后行TEVAR术。结果 3例患者均顺利完成TEVAR术,无逆撕等并发症。术后1个月全主动脉CTA复查显示夹层破口完全封闭,无内漏发生,真腔血流明显改善,壁内血肿明显吸收消退,升主动脉管壁厚度恢复至正常水平;患者临床症状明显好转,无截瘫、死亡等严重并发症发生。结论对伴发升主动脉MH的Standford B型胸主动脉夹层,如果升主动脉内膜完整,降压、降心率处理后症状缓解,在发病14 d后行TEVAR术是安全有效的。     

StanfordB型主动脉夹层动脉瘤的微创腔内治疗

为探讨腔内隔绝术治疗StanfordB型主动脉夹层动脉瘤适应证的选择及并发症的防治原则,回顾了1998年至2000年对32例StanfordB型主动脉夹层动脉瘤实施的微创腔内隔绝术（即经股动脉将支架－人造血管复合移植导入主动脉封闭夹层裂口）。移植物均为直型,长度95－130mm,口径28－40mm。手术操作成功率100％。术后死亡1例,其余无心、肺、肾及截瘫等严重并发症,说明腔内隔绝术治疗StanfordB型主动脉夹层动脉瘤安全、有效,为治疗为病的首选方法。     

Stanford B型主动脉夹层腔内修复术后血管重塑分析

目的 探讨Stanford B型主动脉夹层患者经胸主动脉腔内修复术(TEVAR)治疗后血管形态学转归.方法 回顾性分析51例接受TEVAR术治疗的Stanford B型主动脉夹层患者术前及术后临床及影像学资料,分析术后1个月内、1～6个月、6个月后主动脉各段真假腔内径及假腔血栓化情况.结果 TEVAR术后胸主动脉真腔扩大、假腔缩小,与术前比较差异有统计学意义(P＜0.05),腹主动脉管径真腔和假腔变化较术前无统计学差异(P＞0.05),腹部重要分支动脉血供情况较术前有所改善.结论 TEVAR术治疗Stanford B型主动脉夹层患者的近中期效果确切,但仍需要远期随访观察.     

B型主动脉夹层腔内修复治疗的荟萃分析

目的 分析B型主动脉夹层腔内修复治疗的技术成功率、轻微并发症、严重并发症、脑卒中、截瘫等的发生率.方法 系统收集1999年至2009年Medline收录的有关B型主动脉夹层腔内修复治疗文献,通过制定纳入和排除标准,对所得数据进行汇总分析.结果 在收录的12篇文献中,共有病例数761例,B型主动脉夹层腔内修复治疗的技术成...     

Standford B型主动脉夹层腔内修复术后主动脉重塑效果

目的 系统性回顾Standford B型主动脉夹层腔内修复术(TEVAR)后主动脉重塑结果.方法 检索已发表的评估TEVAR术后主动脉重塑文献,系统性回顾Standford B型主动脉夹层形态学测量方法及结果.共纳入19篇文献,其中仅3篇文献采用三维重建软件进行测量.各文献测量变量多为夹层真腔、假腔直径或面积,仅有少数文献计算了真假腔体积.结果 各文献测量的主动脉平面、术后随访时间及测量方法不同,无法进行数据整合.但总体趋势为急性B型夹层患者术后主动脉重塑效果(胸主动脉假腔血栓化比率为80％～90％)优于慢性患者(38％～91.3％),且更具有一致性;降主动脉术后假腔完全血栓化比率高于腹主动脉,降主动脉近端的主动脉重塑效果良好,膈肌角平面以下重塑效果较差.结论 尽管TEVAR术后主动脉重塑的描述方式各异,但多数文献显示夹层累及主动脉范围广者术后重塑效果差,与夹层远端裂口旷置有关.覆膜支架长度、治疗时间等因素对术后重塑均有影响.统一的评估标准有利于评估主动脉重塑效果,并为临床决策提供更有力的科学支持.     

动脉覆膜支架腔内隔绝治疗Stanford A型主动脉夹层临床效果

【摘要】 目的 探讨应用主动脉覆膜支架腔内隔绝术治疗Stanford A型主动脉夹层的临床效果。方法 回顾性分析2016年6月至2018年10月在湖南中医药大学第一附属医院接受主动脉弓部开窗支架技术全腔内隔绝升主动脉、主动脉弓及降主动脉近段治疗的14例Stanford A型主动脉夹层患者临床资料。观察术后随访1年临床疗效。结果 14例患者均顺利完成手术。术后1年5例治疗效果理想。术后早期死亡1例,支架近端再发夹层4例,发生Ⅰ型、Ⅱ型内漏各1例,Ⅲ型2例。 结论 对于不能外科修复的A型主动脉夹层,可谨慎选择主动脉弓部开窗支架技术行全腔内修复治疗,但须根据患者自身情况和血管病变特点严格把握适应证。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.     

Bronchial stump fistula :treatment with covered retrievable hinged metallic stents-preliminary clinical experience

Objective To evaluate the preliminaily clinical efficacy and retrievability of a retrievable hinged covered metallic stent in the treatment of the bronchial stump fistula （BSF）. Methods Between April 2003 and March 2005, 8 patients with bronchial stump fistula after pneumonectomy or lobectomy were treated with two types （A and B） of retrievable hinged covered metallic stents. Type A stent was placed in 6 patients and type B in 2 under fluoroscopic guidance. The stent was removed with a retrieval set when BSF was healed or complications occurred. Results Stent placement in the bronchial tree was technically successful in all patients, without procedure-related complications. Immediate closure of the BSF was achieved in all patients after the procedure. Stents were removed from all patients but one. Removal of the stents was difficult in two patients due to tissue hyperplasia. Patients were followed up for 6 - 21 months. Placement of the stents remained stable in all patients except one due to severe cough. Permanent closure of BSF was achieved in 7 （87.5%） of 8 patients. Conclusion Use of a retrievable hinged covered expandable metallic stent is a simple, safe, and effective procedure for closure of the BSF. Retrieval of the stent seems to be feasible. （J Intervent Radiol, 2007, 16： 253-257）     

Prevalence and severity of hip and groin pain in sub‐elite male football: a cross‐sectional cohort study of 695 players

The purpose of this study was twofold: (a) to investigate the prevalence of hip and groin pain in sub‐elite male adult football in Denmark and (b) to explore the association between prevalence and duration of hip and groin pain in the previous season with the Copenhagen Hip and Groin Outcome Score (HAGOS) in the beginning of the new season. In total 695 respondents from 40 teams (Division 1–4) were included. Players completed in the beginning of the new season (July–Sept 2011) a self‐reported paper questionnaire on hip and/or groin pain during the previous season and HAGOS. In total 49% (95% CI: 45–52%) reported hip and/or groin pain during the previous season. Of these, 31% (95% CI: 26–36%) reported pain for >6 weeks. Players with the longest duration of pain during the previous season had the lowest HAGOS scores, when assessed at the beginning of the new season, P < 0.001. This study documents that half of sub‐elite male adult football players report pain in the hip and/or groin during a football season. The football players with the longest duration of pain in previous season displayed the lowest HAGOS scores in the beginning of the new season.