Medicinal plants used by the Bapedi traditional healers to treat diarrhoea in the Limpopo Province,South Africa

Ethnopharmacological relevance

This paper provides ethnobotanical information on medicinal plants used to treat diarrhoea in the Limpopo Province, South Africa. Documentation of this nature usually provides the basis for selecting medicinal plants for future phytochemical and pharmaceutical studies aimed at developing new, effective and affordable plant-derived diarrhoea remedies.

Aim of the study

To record and document medicinal plants used by the Bapedi traditional healers to treat diarrhoea in the Limpopo Province, South Africa.

Materials and methods

In order to record and document medicinal plants used by the Bapedi traditional healers to treat diarrhoea, 51 healers from 17 municipalities covering Capricorn, Sekhukhune and Waterberg districts in the Limpopo Province, South Africa were interviewed between January and July 2011. Data collected included the names of plants, plant part(s) used, methods of herbal preparation, administration, dosage and duration of treatments. Voucher specimens of the plants used by the Bapedi traditional healers to treat diarrhoea were collected, identified and deposited as future reference material at the Larry-Leach Herbarium (UNIN), University of Limpopo.

Results

A total of 20 plant species representing 16 families and 20 genera were found to be commonly used by the Bapedi traditional healers to treat and manage diarrhoea in the Limpopo Province, South Africa. The largest proportion of the medicinal plants belonged to the families Anacardiaceae, Asteraceae, Fabaceae and Malvaceae (10% each). The most frequently used species were Punica granatum (39.2%), Grewia bicolor (33.3%), Dombeya rotundifolia (21.6%), Commiphora marlothii (19.6%) and Acacia senegal (13.7%). The roots were the most commonly used plant part (50%), followed by leaves (20%), bark (15%), fruits (10%), pericarp, seed, tuber and whole plants (5% each). Mono therapies based on preparations made from a single plant species were the most dominant (90%). All medicinal preparations were taken orally for 1 week or until diarrhoea subsided. The therapeutic claims of the medicinal plants documented in this study are well supported by literature, with 70% of the species having anti-diarrhoeal properties or are used as diarrhoea remedies both in South Africa and also in other countries.

Conclusion

This study reveals that local communities in the Limpopo Province, South Africa still depend on traditional medicines for basic healthcare; and the use of traditional medicines is still an integral part of their socio-cultural life.     

Medicinal utilization of exotic plants by Bapedi traditional healers to treat human ailments in Limpopo province,South Africa

Ethnopharmacological relevance

Most exotic plants are usually labelled as alien invasives and targeted for eradication. However, some of these exotic plants play an important role in the traditional primary healthcare sector of the Bapedi culture in the Limpopo Province of South Africa. The medicinal uses of most of these species have neither been documented nor their biological activity evaluated.

Aim of the study

To make an inventory of exotic species employed by Bapedi traditional healers to treat different human ailments in the Limpopo Province, South Africa.

Materials and methods

Semi-structured interviews, observation and guided field walks with 52 traditional healers were employed to obtain ethnobotanical data during first half of 2011 on the use of exotic plant species by Bapedi healers to treat human ailments. Based on ethnobotanical information provided by these healers, specimens were collected, numbered, pressed, and dried for identification.

Results

A total of 35 exotics species belonging to 21 families and 34 genera, mostly from the Fabaceae and Solanaceae (11.4% for each), Apocynaceae and Asteraceae (8.5% for each) were used by Bapedi healers to treat 20 human ailments. Trees (45.7%) and herbs (37.1%) are the primary source of medicinal plants. Species most frequently reported were used for the treatment of hypertension (35%), diabetes mellitus, erectile dysfunction and gonorrhoea (25% for each). The highest consensus from individual accounts of the traditional healers on the use of exotic plant remedies in this study was noted for the three ailments. These were for Catharanthus roseus (gonorrhoea, 60%), Punica granatum (diarrhoea, 38.4%) and Ricinus communis (sores, 21.5%). Of the 35 exotic plant species recorded, 34.2% are regulated by the Conservation of Agricultural Resources Act (1983) (CARA) No. 43 of 1983 either as worst weeds or invaders.

Conclusion

The present study demonstrated that exotic plant species play an important part as medicinal remedies employed by Bapedi healers to treat different human diseases in the Limpopo Province. The use of these species as alternative sources of medicinal remedies could alleviate harvesting pressure of wild indigenous plants, thereby enhance biodiversity's region. However, there is a need to formulate an appropriate policy to retain some of the useful medicinal exotics (listed under CARA No. 43 of 1983) within the environment before their medicinal value vanishes as they are eradicated through management strategies adopted by the South African government.     

Traditional plant-based remedies to control gastrointestinal disorders in livestock in the regions of Kamina and Kaniama (Katanga province,Democratic Republic of Congo)

Ethnopharmacological relevance

Gastrointestinal parasitic diseases present one of the main constraints hindering the productivity of the livestock sector (goat and cattle). Due to the limited availability and affordability of deworming drugs, traditional herbal remedies are still frequently used. The study aims at collecting traditional knowledge on local plants and remedies used to treat gastrointestinal parasitoses in livestock in two adjacent territories (Haut-Lomami district).

Material and methods

A field survey was carried out in a part of the Haut-Lomami district (province of Katanga). A semi-structured questionnaire was used to interview 44 people including farmers, traditional healers and livestock specialists (veterinarians and agronomist), identified as using or practicing traditional medicine. To prepare botanically identified herbarium specimens, cited plants were collected with the participation of interviewed people.

Results

Although interviewed people cannot precisely identify the etiology of gastrointestinal disorders/parasitoses in domestic animals, they treat the condition with herbals collected in their near environment. Nineteen different traditional remedies were collected and described; 9 plant species were identified as commonly used to treat gastrointestinal parasitic infections. From these, Vitex thomasii De Wild (Verbenaceae) appears as the plant most often used.

Conclusion

This survey contributed to the establishment of an inventory of plants used in livestock parasitic treatment in this region of the Democratic Republic of Congo. Future studies are needed to confirm the efficacy and safety of these traditional remedies.     

Ethnobotanical survey of malaria prophylactic remedies in Odisha,India

Aim of the study

To investigate the plants traditionally used for prevention of malaria in Cuttack, Gajapati and Koraput districts of Odisha state, eastern India.

Materials and methods

An ethnobotanical survey was carried out among 20 traditional healers who were sampled based on recommendations of local elders and local non-government organizations. Data were collected through semi-structured interview.

Results

The study revealed the use of 16 traditional plant species belonging to 12 families for prevention of malaria. Andrographis paniculata, Azadirachta indica, Nyctanthes arbor-tristis, Ocimum sanctum, Piper nigrum, Zingiber officinale were the most commonly reported plants for their malaria prophylactic use by the healers of three districts of Odisha. Most of the remedies were used in decoction form.

Conclusions

Findings of this study provide a lead to explore traditional plants for malaria preventive potential through further pre-clinical and clinical studies.     

Ethnobotanical survey of medicinal plants used by Bapedi healers to treat diabetes mellitus in the Limpopo Province, South Africa

Ethnopharmacological relevance

Bapedi phytomedicine employ a range of plant species to treat diabetes mellitus (DM). Existing literature partially support the use of certain species for this purpose.

Aim of the study

To report on Bapedi medicinal plants employed to treat DM.

Materials and methods

A semi-structured questionnaire was employed to conduct a survey on medicinal plants used by Bapedi traditional healers in their DM management protocol. Fifty-two traditional healers from 16 municipalities, covering three districts, were interviewed during the first half of 2011.

Results

A total of 24 plant species belonging to 20 families, mostly from the Asteraceae (13%), Cucurbitaceae and Sapotaceae (8%), were used to treat diabetes mellitus. Plant parts mostly preferred were roots and leaves. A decoction of these is most commonly used to make extracts, which are then taken orally for a period of one week. Mimusops zeyheri (29%), Helichrysum caespititium (25%), Plumeria obtusa (21%), Aloe marlothii subsp. marlothii, Hypoxis iridifolia and Moringa oleifera (17% each), were repeatedly mentioned by the traditional healers as most used for the management of diabetes mellitus in the study area. Plumeria obtusa and Momordica balsamina are exclusively used to treat diabetes mellitus, and only in the Sekhukhune District.

Conclusion

It is concluded that Bapedi traditional healers do have a basic understanding of the causes and remedial action required in the treatment of diabetes mellitus.     

The importance of botellas and other plant mixtures in Dominican traditional medicine

Ethnopharmacological relevance

Plant mixtures are understudied in ethnobotanical research.

Aim of the study

To investigate the importance of plant mixtures (remedies consisting of at least two plants) in Dominican traditional medicine.

Materials and methods

A Spanish language questionnaire was administered to 174 Dominicans living in New York City (NYC) and 145 Dominicans living in the Dominican Republic (DR), including lay persons (who self-medicate with plants) and specialists (traditional healers). Plants were identified through specimens purchased in NYC botánica shops and Latino grocery shops, and from voucher collections.

Results

The percentage of mixtures as compared to single plants in plant use reports varied between 32 and 41%, depending on the geographic location (NYC or DR) and participant status (lay person or specialist). Respiratory conditions, reproductive health and genitourinary conditions were the main categories for which Dominicans use plant mixtures. Lay persons reported significantly more mixtures prepared as teas, mainly used in NYC to treat respiratory conditions. Specialists mentioned significantly more botellas (bottled herbal mixtures), used most frequently in the DR to treat reproductive health and genitourinary conditions. Cluster analysis demonstrated that different plant species are used to treat respiratory conditions as compared to reproductive health and genitourinary conditions. Interview participants believed that combining plants in mixtures increases their potency and versatility as medicines.

Conclusions

The present study demonstrates the importance and complexity of plant mixtures in Dominican traditional medicine and the variation in its practices influenced by migration from the DR to NYC, shedding new light on the foundations of a particular ethnomedical system.     

Ethnobotanical survey on medicinal plants used by Guinean traditional healers in the treatment of malaria

Ethnopharmacological relevance

The objective of the present study was to collect and document information on herbal remedies traditionally used for the treatment of malaria in Guinea.

Materials and methods

The survey was carried out from May 2008 to September 2010 and targeted traditional medical practitioners and herbalists. The questionnaire and oral interviews were based on the standardized model which was prepared by the “Centre de Recherche et de Valorisation des Plantes Médicinales (CRVPM) – Dubréka”.

Results and discussion

A total of 258 people (141 males and 117 females) from which 150 traditional healers and 108 herbalists were interviewed. The age of informants ranged from 28 to 82 years old. 57% (149/258) of the interviewees were more than 50 years old. The respondents had good knowledge of the symptoms of malaria, and a fairly good understanding of the causes. One hundred thirteen plant species were recorded, out of which 109 were identified. They belonged to 84 genera and 46 families. The most frequently cited plants were Vismia guineensis, Parkia biglobosa, Nauclea latifolia, Harungana madagascariensis, Terminalia macroptera, Crossopteryx febrifuga, Terminalia albida, Annona senegalensis, and Nauclea pobeguinii. The leaves were most frequently used (80/113 species), followed by stem bark (38/113 species) and roots (4/113 species). The remedies were mostly prepared by decoction (111 species), followed by maceration (seven species). Only one species was prepared by infusion.

Conclusion

The present study showed that traditional healers in Guinea have a consistent knowledge of antimalarial plants. Further research should be carried out to compare the anti-malarial activity of the different species, and to check if their use against malaria can be scienti?cally validated.     

Ethnobotanical study of medicinal plants used for the treatment of malaria in plateau of Allada,Benin (West Africa)

Background

Malaria remains one of the most important illnesses in sub-Saharan Africa. In Benin, it constitutes a major public health preoccupation particularly for children and pregnant women. Until now, population still mostly relies on herbal medicine for malaria healing. Hence this study was carried out to document the medicinal plants used in the plateau of Allada in Benin and to assess local knowledge on traditional medicine in the management of malaria and related symptoms.

Materials and methods

Data were collected from 53 informants composed of 23 traditional healers and 30 medicinal plants sellers using a structured questionnaire.

Results

A total of 82 plants species belonging to 78 genera in 43 plant families were recorded as antimalarial in the study area. The families of Rubiaceae and Caesalpiniaceae were the most represented with seven species each. High informant consensus factor (ICF) was recorded in the treatment of malaria (ICF=0.90). High fidelity level (FL=100%) was also recorded for 45.67% of the species used as antimalarial. Dichapetalum madagascariense was the species of high relative frequency of citation (RFC=0.81). The dominant plant parts used in the preparation of remedies were leaves (68%). The decoction (79%) was the main mode of preparation, while oral route (92%) was the principal route of remedies administration.

Conclusion

This study provides plant species used in the plateau of Allada for malaria and related symptoms treatment. We hope that this study could be important for the conservation of traditional knowledge on the antimalarial plants and the improvement of malaria management. However, several plant species used as antimalarial by the traditional medicine practitioners in the study area need to be screened in order to identify the species having antiplasmodial activity.     

Management of diabetes in Guinean traditional medicine: An ethnobotanical investigation in the coastal lowlands

Ethnopharmacological relevance

This survey was carried out in the coastal lowlands of Guinea–Conakry in order to make an inventory of plants used by traditional healers, herbalists and diabetic patients for the management of diabetes mellitus.

Materials and methods

Frequent ethnomedical and ethnobotanical investigations were conducted from June 2008 to December 2009 in Conakry, Kindia, Forécariah, Dubréka, Boke, Fria and Boffa. It is a cross-sectional survey and data collection is based on the interactive method. During this period a total of 112 people aged from 39 to 76 years old were interviewed.

Results

During this investigation 146 plant species belonging to 55 families were collected. The most cited plants were Anacardium occidentale L. and Ficus spp., while the Fabaceae family was the most represented, followed by the Euphorbiaceae and Rubiaceae. The most frequently plant parts used by the traditional healers and the herbalists were the stem-bark and decoctions the most common preparation mode.

Conclusions

It is clear that a variety of plants is used in the management and treatment of diabetes. Due to the increasing prevalence of type 2 diabetes, there is an urgent need for scientific investigations to rationalise the use of these traditional remedies, which could represent accessible alternative medicines for the Guinean populations.     

Ethnobotanical survey of antidiarrhoeal plants of Parinche valley,Pune district,Maharashtra, India

Ethnopharmacological relevance

Maharashtra is the third largest state in India with a large tribal population. Documentation of traditional knowledge through ethnobotanical studies is important for conservation and utilization of indigenous knowledge. Diarrhoeal diseases are the second largest cause of morbidity in rural India. Medicinal plants given by the traditional healers of Parinche in Pune district, Maharashtra are known to be efficacious for many common ailments, including diarrhoeal diseases.

Aim of the study

Ethnobotanical survey of antidiarrhoeal plants from Parinche valley towards the documentation and conservation of traditional knowledge.

Materials and methods

Interviews and inquiries were conducted amongst traditional healers, indigenous communities and village elders.

Results

One hundred and eighty two plants used by tribes and natives for different ailments were documented of which 28 flowering plants were for diarrhoea. Leaf was the most preferred plant part. Amongst the 28 plants, antidiarrhoeal activity of five plants viz., Caesalpinia sepiaria, Dioscorea pentaphylla, Launaea pinnatifida, Syzygium rubicundum and Ziziphus jujuba has not been reported previously. Two species viz., Ziziphus xylopyra and Syzygium rubicundum are endemic to India.

Conclusion

Parinche valley is an ethnobotanically rich area with abundant availability and knowledge of medicinal plants that can serve as a model for low cost health care.     

Herbal medicines used in the treatment of diabetes mellitus in Arunachal Himalaya, northeast, India

Ethnopharmacological relevance

Medicinal plants have played an important role in treating and preventing a variety of diseases throughout the world. Khampti tribal people living in the far-flung Lohit district of the Eastern Arunachal Himalaya, India still depend on medicinal plants and most of them have a general knowledge of medicinal plants which are used for treating a variety of ailments. This survey was undertaken in Lohit district in order to inventory the medicinal plants used in folk medicine to treat diabetes mellitus.

Materials and methods

Field investigations were conducted in seventeen remote villages of Lohit district starting from April 2002 to May 2004 through interviews among 251 key informants who were selected randomly during our household survey. To elucidate community domains and determine differences in indigenous traditional knowledge of medicinal plants with anti-diabetic efficacy, we repeated our field survey starting from April 2008 to May 2010 with one hundred traditional healers locally called as “Chau ya” in Khampti of Lohit district. “Chau ya” traditional healers who know and use medicinal plants for treating diabetes mellitus were interviewed using a semi-structured questionnaire.

Results

This study reports an ethnobotanical survey of medicinal plants in Lohit district of Arunachal Pradesh reputed for the treatment of diabetes mellitus. Forty-six plant species were identified in the study area to treat diabetes mellitus by the Khamptis “Chau ya” traditional healers. Comparative published literature survey analysis of this study with other ethnobotanical surveys of plants used traditionally in treating diabetes mellitus suggests that eleven plant species make claims of new reports on antidiabetic efficacy. These plant species are Begonia roxburghii, Calamus tenuis, Callicarpa arborea, Cuscuta reflexa, Dillenia indica, Diplazium esculentum, Lectuca gracilis, Millingtonia hortensis, Oxalis griffithii, Saccharum spontaneum, and Solanum viarum. Some of the plants reported in this study have an antidiabetic effect on rodent models but none have sufficient clinical evidence of effectiveness.

Conclusions

The wide variety of medicinal plants that are used to treat diabetes mellitus in this area supports the importance of plants in the primary healthcare system of the rural people of Lohit district of Arunachal Pradesh. The finding of new plant uses in the current study reveals the importance of the documentation of such ethnobotanical knowledge.     

An ethnobotanical survey of medicinal plants used in Rwanda for voluntary depigmentation

Ethnopharmacological relevance

Voluntary depigmentation, a very common practice in sub-Saharan Africa, often performed with pharmaceutical products diverted from their pharmacological use, may cause severe dermatological and systemic side effects. The present work aims at investigating whether and which herbs were used in Rwanda for similar purposes before the advent of the current depigmentation craze; this may give clues at herbal treatments possibly advantageous compared to current products.

Material and methods

Sixty-one traditional healers, mostly representatives of their associations, were surveyed by questionnaires for knowledge and practice of voluntary depigmentation. Recipes or plants used, plant parts, harvest area, preparation methods, dosage and route of administration were recorded. Most of the cited herbs were harvested with the help of traditional healers and identified by comparison with voucher specimens; herbal vouchers of the five most cited herbs were deposited in official herbaria.

Results

All surveyed traditional healers have knowledge of voluntary depigmentation; the population currently practicing do not recourse to their services but obtain bleaching products directly from the market. Traditional healers disclosed recipes prescribed or self-used (often by women) in their youth; others cited recipes are used to treat skin diseases with properties of “clarification”, “black skin stain removal”, in cases of hyperpigmentation, and/or “skin softening”. Curiously, from the 28 recipes cited by traditional healers, all are mono-herbal preparations; most of the plants are mixed with butter for application to the skin.

Conclusion

Compared to other pathophysiological conditions, there is currently a very limited use of herbal preparations for depigmentation. Five herbs had a citation percentage equal or above to 50%, Brillantaisia cicatricosa Lindau (Acanthaceae), Chenopodium ugandae (Aellen) Aellen (Chenopodiaceae), Dolichopentas longiflora Oliv. (Rubiaceae), Protea madiensis Oliv. (Proteaceae) and Sesamum angolense Welw. (Pedaliaceae); in vitro experiments indicated a modulation of melanogenesis by these plant extracts, confirming the information obtained from traditional healers.     

Inhibitory properties of selected South African medicinal plants against Mycobacterium tuberculosis

Ethnopharmacological relevance

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB) is the most commonly notified disease and the fifth largest cause of mortality. One in 10 cases is resistant to treatment in some areas. Several plants are used locally to treat TB-related disease.

Aims of the study

The aim was to screen selected South African medicinal plants used to treat TB and related symptoms by traditional healers for antimycobacterial activity.

Materials and methods

Ethnobotanical information on these plants was obtained. Crude acetone, methanol, hexane and ethanol extracts of 21 selected medicinal plants obtained in Venda, South Africa were screened for their ability to inhibit MTB H₃₇Ra and a clinical strain resistant to first-line drugs and one second-line drug using tetrazolium microplate assay to determine the minimum inhibitory concentration (MIC). Results were analyzed using Microsoft Excel 2007 and One way ANOVA; p < 0.05 was considered for statistical significance.

Results

Few acetone extracts were active against MTB with MIC under 100 μg/mL. Four plants showed lower MIC values; Berchemia discolor Klotzsch Hemsl 12, 5 μg/mL on H₃₇Ra and 10.5 μg/mL on the clinical isolate, Bridelia micrantha Hochst. Baill (25 μg/mL), Warbugia salutaris Bertol. F Chiov (25 μg/mL), and Terminalia sericea Burch ex D. F (25 μg/mL) on both H₃₇Ra and clinical isolate. However, the roots of Ximenia caffra Sond. Var. caffra, barks of Sclerocarya birrea (A Rich) Hochst, Asclepias fruticosa L, tubers of Allium sativum L, leaves of Carica papaya L, Solanum panduriforme E. Mey C, and roots of Securidaca longepedunculata Fresen gave MIC greater than 100 μg/mL.

Conclusion

The acetone extracts of Berchemiadiscolor, Bridelia micrantha, Terminalia sericea and Warbugia salutaris could be important sources of mycobactericidal compounds against multidrug-resistant MTB.     

Epilepsy in the Renaissance: A survey of remedies from 16th and 17th century German herbals

Ethnopharmacological relevance

Before modern anticonvulsive drugs were developed people in central Europe used herbal remedies to treat epilepsy. Hundreds of different plants for this indication can be found in German herbals of the 16th and 17th centuries. Here we compile these plants and discuss their use from a pharmacological perspective.

Materials and methods

Nine of the most important European herbals of the 16th and 17th century including Bock (1577), Fuchs (1543), Mattioli (1590), 103 and 104, Brunfels (1532), Zwinger (1696), and Tabernaemontanus (1591, 1678) were searched for terms related to epilepsy, and plants and recipes described for its treatment were documented. We then searched scientific literature for pharmacological evidence of their effectiveness. Additionally the overlapping of these remedies with those in De Materia Medica by the Greek physician Dioscorides was studied.

Results

Two hundred twenty one plants were identified in the herbals to be used in the context of epilepsy. In vitro and/or in vivo pharmacological data somehow related to the indication epilepsy was found for less than 5% of these plants. Less than 7% of epilepsy remedies are in common with De Materia Medica.

Conclusions

Numerous plants were used to treat epilepsy in the 16th and 17th centuries. However, few of these plants have been investigated with respect to pharmacological activity on epilepsy related targets.     

Medicinal plants used by traditional medicine practitioners in the treatment of tuberculosis and related ailments in Uganda

Aim of the study

Tuberculosis (TB) remains one of the most difficult ailments to control in the world today. The emergence of drug resistant strains has made previously effective and affordable remedies less effective. This has made the search for new medicines from local traditional medicines urgent. The specific objectives of this study were to (1) identify plant species used in the treatment of TB, their methods of preparation and administration, (2) document TB recognition, and (3) document medicine processing and packaging practices by traditional medicine practitioners (TMPs).

Methods

We interviewed 32 TMPs from the districts of Kamuli, Kisoro and Nakapiripirit using a guided questionnaire.

Results

We documented 88 plant species used to treat TB. Seven of these, Eucalyptus spp., Warburgia salutaris (G. Bertol.) Chiov., Ocimum suave Willd., Zanthoxylum chalybeum Engl., Momordica foetida Schum., Persea americana Mill. and Acacia hockii De Wild. were mentioned by three or more TMPs. Medicines were prepared mostly as mixtures or infrequently as mono-preparations in dosage forms of decoctions and infusions. They were administered orally in variable doses over varying periods of time. The TMPs did not know how to preserve the medicines and packaged them in used water bottles. Almost all TMPs mentioned the most important signs by which TB is recognised. They also knew that TB was a contagious disease spread through poor hygiene and crowding.

Conclusions

Local knowledge and practices of treating TB exist in the districts surveyed. This knowledge may be imperfect and TMPs appear to be still experimenting with which species to use to treat TB. There is need to screen among the species mentioned to determine those which are efficacious and safe. The technology of processing, packaging and preserving traditional medicines for the treatment of TB is very basic and needs improving. The TMPs appear to be playing a significant role in primary health care delivery and this lends further justification for the ongoing Uganda government efforts to integrate the allopathic and traditional medicine systems.     

Ethnoveterinary use of southern African plants and scientific evaluation of their medicinal properties

Aim of the study

Livestock keepers in many developing countries with restricted access to orthodox veterinary healthcare services commonly use traditional remedies to treat their animals when disease is encountered. This review collates the documented use of plants in South Africa for healing various ailments in domestic animals, and records bioactivity testing that has been carried out on these plants.

Materials and methods

A literature survey was conducted on the use of plants in South African ethnoveterinary medicine (EVM), as well as on biological activity investigations relating to their ethnoveterinary use where available.

Results

The ethnoveterinary application of plants, and results of screening studies of EVM plant extracts in various bioassays is presented. For diseases such as coughs, wounds, skin diseases, mild diarrhoea and reproductive disorders, EVM may be a cheap and easily accessible alternative to expensive pharmaceuticals. Studies on biological activity of EVM plants can provide indications of promising leads for extracts that can be developed into standardized medications to be used on a commercial basis. Isolation studies on active plants may yield pure active compounds that could be chemically modified to optimize medicinal value and reduce possible toxic effects.

Conclusion

In South Africa, a large proportion of the population relies on traditional remedies to treat themselves and their animals for common diseases. Only a small percentage of EVM plants have been analysed for biological activity or toxic effects, and hence research in this field offers fertile possibilities for future investigation.     

Medicinal plants used in malaria treatment by Prometra herbalists in Uganda

Ethnopharmacological relevance

The aim of the survey was to document medicinal plants used in malaria treatment by Prometra (Promocion de la medicina tradicional amazonica) Traditional Medical Practitioners (TMPs) of Uganda and for search of new antiplasmodial herbal medicines (HMs) for further phytochemical analysis.

Materials and methods

In this study, semi structured guided open and close ended questionnaires were used. Focus group discussions were conducted and key informants were chosen within the TMPs who helped in further discussions of how the herbal remedies where collected, prepared and administered.

Results

A sample size of 51 respondents was randomly selected among the TMPs with the help of their leader. 86 species distributed over 81 genera and 39 families were reportedly being used as herbal remedies in malaria treatment. The TMPs use symptoms like high temperature, shivering, among others in malaria diagnosis an indication that they understand malaria. They emphasized the use of leaves and bark in treatment because they can regenerate and therefore ensure sustainable use of plants rather than the use of roots which would be destructive. These TMPS treat and also advise their patients on preventive measures against malaria attacks like sleeping under mosquito nets, clearing bushes near homesteads, among others which is an indication that they help in the prevention and mitigation of malaria incidences and prevalence in the areas where they live. The Informant Consensus Factor (FIC) value of 0.8 demonstrated that the TMPs of Prometra-Uganda tend to agree with each other in terms of the plant species they use in malaria treatment an indication of quality control in as far as administration of the herbal remedies. Vernonia amygdalina Delile, Bidens pilosa L., Justicia betonica L. were highly cited as being used in malaria treatment with frequencies of mention of 38, 28 and 25, respectively.

Conclusion

TMPs of Prometra-Uganda understand and treat malaria using the available plant diversity from their huge forest and the herbal gardens within Buyija forest. The healers are very keen at plant conservation which is a good practice. Species like Justica betonica may be investigated further for antiplasmodial assays to justify its efficacy.     

Traditional uses of herbal vapour therapy in Manipur,North East India: An ethnobotanical survey

Ethnopharmacological relevance

Vapour-based medicines are an aspect of traditional medicine in North East India. However, no collective studies on this therapy in the region have been attempted. With the changing perception of traditional knowledge, documenting these herbal preparations and the subsequent development of baseline data for applications in further ethnopharmacological research are needed.

Aims of the study

To survey and document the plant species associated with vapour therapy in Manipur, North East India, and to evaluate these traditional practices.

Materials and methods

Semi-structured questionnaires were used to collect information from the Meitei community in the Imphal valley and the Jiribam area in Manipur. Traditional disease concepts were studied along with their corresponding medical terminologies. Plant samples collected from fields, healers' private collections and home gardens were identified. Evaluation of the ethnobotanical data was performed with a modified fidelity level index.

Results

In the study, 41 traditional disease complexes were treated by 13 different routes of administration using 48 mono-ingredient and 17 multi-ingredient compositions. Preparation methods included boiling in water (28%), burning the materials (48%), crushing the materials to release the aroma (21%) and slight heating of the materials (3%). Some of the mono-ingredient recipes reported in the study were observed to have similar uses in other parts of the world, whereas polyherbal remedies were found to be unique without any similar report.

Conclusion

Many compositions mentioned in the paper are still used by the Meitei community. Traditional healers follow their own criteria for selecting medicinal plants. Plants recorded in this ethnobotanical study can suggest methods for selecting and identifying potentially effective plants for future drug candidates. Scientific characterisation of the herbal remedies can contribute to the endorsement of traditional vapour-based therapies in the modern health care systems. Findings from these “new usage” reports of plants and unique combinations of polyherbal compositions indicate the importance of such documentation efforts.     

Nepalese traditional medicine and symptoms related to Parkinson׳s disease and other disorders: Patterns of the usage of plant resources along the Himalayan altitudinal range

Ethnopharmacological relevance

Nepal is a hotspot for cultural and biological diversities. The tremendous diversity of ecosystems and climates and the blend of medicinal practices inherited from Ayurvedic and Traditional Tibetan Medicine are well suited to a study aimed at discovering information about medicinal plants to treat Parkinson’s disease (PD). In addition, this study across Nepal’s altitudinal range is relevant to understanding how cultural and ecological environments influence local traditional medicines. The aim of the study is to document the uses of medicinal plants in three different eco-geographical areas of Nepal (Chitwan–Panchase–Mustang) to treat symptoms related to PD. A second goal is to analyze the impact of culture and environment on the evolution of traditional medicine.

Materials and methods

The study was conducted in five communities located in three different eco-geographical environments and at altitudes ranging from 300 m to 3700 m. We interviewed a total of 56 participants (local people, folk, Ayurvedic and Amchi healers) across the three research areas. We conducted open-ended interviews to document the uses of medicinal plants to treat PD-related symptoms. Information provided by the interviewees suggested that the medicinal plants are also used to treat symptoms related to other disorders. We determined the informant consensus factor as well as the importance of specific plant species to (i) identify plants that are the best candidates to be analyzed experimentally for their potential to treat PD and (ii) perform a cross-cultural comparison of the three areas of study.

Results

This study reports the local uses of 35 different plant species along the Chitwan–Panchase–Mustang altitudinal range. We identify a total of eight plant species that were used in all three research areas, and more specifically one species used to treat PD-like symptoms. We identify a potential dual protective activity of medicinal plants used to treat PD-related symptoms as recent literature suggests that these plants also have anti-cancer properties. In addition, we document that the presence of Ayurvedic healers could influence local practices and that local practices could influence local Ayurvedic practices.

Conclusions

This study documents the uses of medicinal plants to treat symptoms related to PD and other disorders across the Chitwan–Panchase–Mustang altitudinal range. PD is a neurodegenerative disease affecting a growing number of people worldwide. No cures are available to slow the death of the neurons, and there is a critical need to work towards innovative therapeutic strategies. We identify medicinal plants based on traditional practices to help develop a cure for PD. The three areas of study were chosen for their ecological and cultural diversities, and two of these are included in conservation programs (Panchase Protected Forest and Annapurna Conservation Area). The documentation of community–natural resource relationships is another step in the preservation of traditional practices and local biodiversity and a reflection of communities’ rights in the design of conservation programs.