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S Emelianova P Mazzotta A Einarson G Koren 《Clinical and investigative medicine. Médecine clinique et experimentale》1999,22(3):106-110
OBJECTIVE: Although nausea and vomiting of pregnancy is the most common medical condition during pregnancy, there are many unanswered questions regarding its cause, epidemiologic features and optimal management. The objectives of this study were to ascertain the prevalence of nausea and vomiting in a sample of Canadian women, to characterize the distribution of their severity and to investigate the role of vitamin B6 deficiency in their etiology. DESIGN: Prospective study. SETTING: Antenatal counselling service for pregnant women. PATIENTS: Three cohorts of women: a prospective, population-based cohort of 193 women, to estimate the rate and severity of nausea and vomiting (cohort A); a cohort of 555 women who sought advice for nausea with or without vomiting, to study the correlation between the maximal daily number of episodes of vomiting and maximal weight loss (cohort B); and a prospective cohort of 301 women who reported vomiting, to correlate vitamin supplementation with vomiting (cohort C). INTERVENTIONS: All 3 cohorts were interviewed during the counselling session, and cohort B was followed up prospectively. OUTCOME MEASURES: Frequency of nausea and vomiting, weight loss, maximal number of daily episodes of vomiting, rate of multivitamin supplementation. RESULTS: Overall, 67% of the women in cohort A reported experiencing nausea or vomiting, or both; 22% reported vomiting, and 9% experienced weight loss. In cohort B there was a significant correlation between the maximal number of daily episodes of vomiting and maximal weight loss, although there was wide variation (r2 = 0.25, p < 0.001). There was a highly significant correlation between the number of daily vomiting episodes and mean weight loss (r2 = 0.99). In cohort C, vomiting was significantly associated with lack of supplementation with multivitamins before 6 weeks' gestation (p = 0.002). CONCLUSIONS: The relation between number of daily vomiting episodes and mean weight loss may serve as a clinical tool to assess the severity of nausea and vomiting in pregnancy and the success of anti-emetics and rehydration regimens. Further study is needed to elucidate the biologic basis of the observed association between vomiting and lack of multivitamin supplementation in early pregnancy. 相似文献
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心血管疾病是我国的多发病和人群的主要死亡原因之一,而高血压已成为中老年人的常见病,是冠心病、脑卒中最主要的危险因素,已成为世界性公共卫生问题。随着我国经济的发展及人们生活水平的日益提高,我国在1958年、1979年、1991年分别进行了全国性的高血压普查,结果表明,我国高血压患病率在持续上升,且上升速度逐年加快。由于文化程度、生活习惯以及信息来源不足的差异也是导致城居民高血压患病率持续上升的重要原因,因此指导城乡居民进行合理的饮食,对预防高血压的发生、发展有着重要的意义。 相似文献
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Harold S. Zamansky Roger F. Brightbill 《The International journal of clinical and experimental hypnosis》2013,61(4):279-290
A form of the Semantic Differential, containing 9 concepts related to hypnosis and research, was administered to 96 hypnotically inexperienced male Ss. The Ss were later asked to volunteer for a hypnotic experiment, and the hypnotic susceptibility of all volunteers (N = 51) was then determined. Semantic Differential responses of volunteers and nonvolunteers and of highly susceptible and unhyp-notizable Ss were compared. Differences between groups, in both comparisons, were generally not statistically significant, a finding which suggests that there is no simple relationship between paper-and-pencil measures of attitudes and volunteering for hypnotic experiments or hypnotizability. 相似文献
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In 1980, the World Health Organization declared smallpox eradicated from the world; the last known natural case had occurred in Somalia in 1977, and the United States had stopped routinely vaccinating its citizens in 1972. However, with increasing concerns regarding domestic and international terrorism, smallpox has resurfaced as a potential threat to global health. We review the direct and indirect modes of smallpox transmission and how patterns of transmission vary substantially, depending on the severity of circulating disease, vaccination status, environmental and socioeconomic factors, and the setting of an outbreak. We examine mechanisms for controlling outbreaks of disease and preventing further transmission in the event of an outbreak, with an emphasis on smallpox vaccination. 相似文献
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目的 为了解麻疹和风疹的临床症状特征,并评价不同麻疹疑似病例定义的监测效果。 方法 2010年在北京市昌平区开展发热出疹性病例的流行病学调查,收集病例的一般情况、临床症状和体征、免疫史等信息。 结果 麻疹和风疹在发热程度、皮疹持续时间、发热至出疹时间间隔以及卡他症状、结膜炎、淋巴结肿大和关节疼痛等临床症状和体征有明显差异。北京市和卫生部麻疹疑似病例诊断标准的敏感度和特异度分别为94%、50%和45%、94%。如以"发热≥38℃,发热后第3天或以后出疹,并伴有卡他症状或结膜炎之一者"作为麻疹疑似病例诊断标准,敏感度和特异度分别为81%和92%。 结论 北京市麻疹发病率较低,北京市麻疹疑似病例诊断标准的敏感度较高,对于消除麻疹,及时发现病例有效。在消除麻疹进程中,要视不同发病率选择适宜的监测病例定义,以提高监测效力。 相似文献
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目的了解和分析国内唇腭裂专科护理工作发展的现状。方法检索并分析万方医学网、中国知网、Springer Link及PubMed英文数据库近6年有关唇腭裂手术的围术期护理、患儿的喂养、手术安全管理、围术期疼痛研究以及心理护理的相关文献。结果共检索出国内文献89篇(核心期刊20篇)、国外文献22篇,其中围术期护理38篇、患儿的喂养16篇、手术安全管理10篇、围术期疼痛研究10篇、心理护理15篇。结论与国外文献相比,国内论文总结和回顾性居多,应增加研究探讨性论文,从而促进唇腭裂临床护理工作专科化的发展。 相似文献
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现代残疾康复理念、政策与社区康复体系研究 总被引:1,自引:0,他引:1
本研究分析了当代残疾康复的理念和理论架构,构建了以国际公约、决议和政策、国内法律和政策以及操作性工具3个层次的康复理论体系;运用包容性发展,分析探讨了当代社区康复的体系和特点;就发展康复事业、为残疾人提供全面系统的康复服务提出相关的政策建议。 相似文献
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目的探讨农村与城市儿童的个性行为特征。方法将97名农村学龄儿童设为农村组,97名城市学龄儿童设为城市组,采用艾森克个性问卷一儿童版和Achenbach’s 行为量表一儿童版进行评定分析。结果两组学龄儿童艾森克个性问卷各维度评分均无显著性差异(P均〉0.05),且与全国常模相一致(P均〉0.05);农村组男学童Achenbach’s行为量表违纪行为、攻击行为及外向型因子分均显著高于城市组,女学童退缩、社交问题因子分均显著高于城市组(P〈0.05或0.01),其他因子分均无显著性差异(P均〉0.05)。结论农村与城市儿童个性无显著差异,而农村儿童存在较多的行为问题,可能与其所受教养和生活方式有关。 相似文献
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Biomaterials have drawn considerable attention in recent years because of environmental concerns. In this paper, several different poly(lactide)-b-poly(butadiene)-b-poly(lactide) (PLA-b-PB-b-PLA) triblock copolymers were synthesized by the bulk ring-opening polymerization of lactide initiated by flexible macro-initiator hydroxyl-terminated polybutadiene (HTPB) by adjusting the ratio of HTPB to lactide and the optical isomer of lactide. Afterwards, a chain-extension reaction with hexamethylene diisocyanate (HDI) was carried out to prepare (PLA-b-PB-b-PLA)n multi-block copolymers with enhanced molecular weight. The structures and properties of these block copolymers were then characterized by gel permeation chromatography (GPC), nuclear magnetic resonance (NMR), differential scanning calorimetry (DSC), atomic force microscope (AFM) and Fourier-transform infrared (FTIR). Toughening effect of the (PLA-b-PB-b-PLA)n multiblock copolymers on biodegradable poly(l-lactide) (PLLA) film was investigated and the blended film with higher (poly(d-lactide)-b-poly(butadiene)-b-poly(d-lactide))n (PDLA-b-PB-b-PDLA)n loading (15 wt%) exhibited better toughness nearly without loss of the tensile strength. The mechanical properties of the (PLA-b-PB-b-PLA)n/PLLA blended film were proved to be influenced by the different isomers of PLA and rubbery PB chains.Toughen effect of the multiblock copolymers (PLA-b-PB-b-PLA)n on PLLA was investigated and the mechanical properties of the blended films were proved to be influenced by the optical isomers of PLA, stereocomplexation and the rubbery PB chains. 相似文献
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脑卒中偏瘫的躯干与骨盆控制及站立与步行训练 总被引:4,自引:0,他引:4
脑卒中偏瘫患者的躯干屈伸功能严重障碍 ,经康复治疗后 ,躯干的屈伸功能可显著提高[1] 。因此 ,在脑卒中偏瘫患者的康复训练中 ,应重视躯干、骨盆控制能力的训练 ,以提高行走能力。1直立躯干的训练在偏瘫早期 ,由于长期卧床及肌张力低下等原因 ,很多患者在坐位时都采取了骨盆后倾、脊柱弯曲的姿势 (图 1a)。对此 ,应及早通过训练来矫正 ,使患者躯干直立 ,为以后的行走打下良好的基础 (图 1b)。2躯干控制训练患者取椅坐位 ,双足着地 ,用健手握住患侧手腕 ,双手一齐向下伸 ,然后直立起身体 ,抬头后仰 (图2a ,b)。3躯干旋转训练患者取坐位 … 相似文献
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Basiye FL Schoone GJ Beld M Minnaar R Ngeranwa JN Wasunna MK Schallig HD 《Diagnostic microbiology and infectious disease》2011,69(1):66-73
Molecular tools continue to be important in the prevention and control of parasitic diseases. However, using these techniques directly in the field remains a major challenge. Therefore, the preservation of clinical samples collected from endemic field areas for later analysis remains an important preanalytical process. This study aimed at identifying a suitable protocol for stabilization and preservation of RNA and DNA in bioclinical specimens for Trypanosoma, Leishmania, and Plasmodium research. Both spiked and unspiked blood samples were preserved in 7 protocols (different media; storage temperatures). Samples were evaluated for possible degradation of DNA and RNA along the storage duration up to the 10th week. Nucleic acid targets were assessed as follows: (i) Trypanosoma and Plasmodium RNA analysis was done using real-time nucleic acid sequence-based amplification (RT-NASBA) for 18S rRNA and for stage-specific Pfs25 mRNA, respectively; (ii) Trypanosoma DNA assessment analysis was conducted by using a conventional PCR for 18S rDNA; (iii) Leishmania RNA analysis was performed with a quantitative NASBA for 18S rRNA and Leishmania DNA assessment with an RT-PCR for 18S rDNA. Findings suggested that a newly developed L3™ buffer proved to be reliable and suitable for both short- and long-term preservation of parasite nucleic acid material. This buffer is envisaged to be suitable for utilization in field situations where resources are limited. 相似文献