学龄期注意缺陷多动障碍男生执行功能异质性与父母压力相关性的病例对照研究

目的：探讨注意缺陷多动障碍（ADHD）儿童的执行功能异质性与父母压力的关系。 方法：本研究为病例对照研究，病例组为学龄期ADHD男生（执行功能缺陷亚组和完好亚组），对照组为正常发育学龄期男生。分别以STROOP色-词测验、威斯康辛卡片分类测验 (WCST)、剑桥神经心理成套测验 (CANTAB)和韦氏儿童智力量表第4版（WISC-Ⅳ）的相应指标评价执行功能，Swanson Nolan and Pelham, Version Ⅳ(SNAP-Ⅳ)量表父母版注意缺陷、多动/冲动分量表评估儿童的ADHD临床症状，SNAP-Ⅳ对立违抗得分和Conners父母症状问卷（PSQ）评估儿童的共病情况，以父母压力指数量表（PSI）评估父母压力。 结果：ADHD组104例、对照组47例进入本文分析。两组年龄差异有统计学意义，两组SNAP-Ⅳ和PSQ各因子差异均有统计学意义。执行功能：执行功能缺陷亚组（51例）和完好亚组（53例）差异有统计学意义，执行功能完好亚组和对照组差异无统计学意义。ADHD组及其亚组较对照组比较，不论在儿童维度及总分、家长维度及总分、父母压力总分均显著升高，执行功能完好亚组较缺陷亚组除在注意缺陷多动因子中存在差异，在儿童维度及总分、家长维度及总分、父母压力总分差异均无统计学意义。 结论：ADHD儿童会带来父母压力增加，执行功能完好也不能改善父母压力的状况。     

学龄前儿童注意缺陷多动障碍决策树预测模型的前瞻性研究北大核心CSCD

目的探讨注意力时间联合行为量表在学龄前儿童注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)筛检中的应用价值。方法ADHD组来自2019年2月至2020年3月福建省妇幼保健院确诊的学龄前ADHD儿童200例,对照组来自同期同医院或幼儿园体检的儿童200例,记录注意力时间,并使用中文版SNAP-Ⅳ评定量表父母版(Chinese Version of Swanson Nolan and Pelham,VersionⅣScale-Parent Form)评估症状。以临床诊断为金标准,应用决策树分析法,评估注意力时间联合行为量表筛查ADHD的临床应用价值。结果ADHD组SNAP-Ⅳ条目1、4、7、8、10、11、14、15、16、18、20、21、22的得分高于对照组(P<0.05),注意力时间短于对照组(P<0.05)。将单因素分析2组间差异有统计学意义的变量作为自变量制定决策树模型,该模型预测ADHD的准确率为81%,预测非ADHD的准确率为69%,总体准确率为75%,受试者工作特征曲线下面积为0.816(95%CI:0.774~0.857,P<0.001)。结论基于注意力时间和行为量表建立的学龄前儿童ADHD筛查的决策树模型准确性较高,可用于临床快速进行儿童ADHD初筛,促进开展全人口ADHD筛查与管理。     

注意缺陷多动障碍伴孤独症特征儿童社交相关行为问题及执行功能研究

目的比较注意缺陷多动障碍(ADHD)伴孤独症特征(ATs)儿童和一般ADHD儿童临床特征及执行功能的差异。方法 2015年12月至2017年1月收集ADHD患儿临床资料,根据其社交反应量表(SRS)得分,选择ADHD伴ATs(ADHD-ATs组)80例和一般ADHD(ADHD组)95例;比较两组患儿SNAP-Ⅳ评定量表、Conners父母用症状问卷及执行功能行为评定量表(BRIEF)的评估结果。结果两组患儿的年龄、性别及智商差异无统计学意义(P0.05)。与ADHD组比较,ADHD-ATs组SNAP-Ⅳ量表中多动核心症状、Conners问卷中的行为问题更明显,差异均有统计学意义(P0.05)。"冷"、"热"执行功能比较中,相较ADHD组,ADHD-ATs组的BRIEF得分均更高,心理理论(口语)得分和总分更低,差异均有统计学意义(P0.05)。回归分析显示,"冷"、"热"执行功能与患儿社交行为问题有显著相关性[BRIEF行为管理指数:β=-1.17,P0.01,95%CI:-2.00~-0.34;心理理论(口语):β=0.72,P0.001,95%CI:0.51~0.93]。结论 ADHD-ATs患儿较一般ADHD患儿的多动核心症状更为明显,执行功能上受损也更为严重。     

注意缺陷多动障碍伴孤独症特征儿童社交相关行为问题及 执行功能研究#br#

目的比较注意缺陷多动障碍(ADHD)伴孤独症特征(ATs)儿童和一般ADHD儿童临床特征及执行功能的差异。方法 2015年12月至2017年1月收集ADHD患儿临床资料,根据其社交反应量表(SRS)得分,选择ADHD伴ATs(ADHD-ATs组)80例和一般ADHD(ADHD组)95例;比较两组患儿SNAP-Ⅳ评定量表、Conners父母用症状问卷及执行功能行为评定量表(BRIEF)的评估结果。结果两组患儿的年龄、性别及智商差异无统计学意义(P0.05)。与ADHD组比较,ADHD-ATs组SNAP-Ⅳ量表中多动核心症状、Conners问卷中的行为问题更明显,差异均有统计学意义(P0.05)。"冷"、"热"执行功能比较中,相较ADHD组,ADHD-ATs组的BRIEF得分均更高,心理理论(口语)得分和总分更低,差异均有统计学意义(P0.05)。回归分析显示,"冷"、"热"执行功能与患儿社交行为问题有显著相关性[BRIEF行为管理指数:β=-1.17,P0.01,95%CI:-2.00~-0.34;心理理论(口语):β=0.72,P0.001,95%CI:0.51~0.93]。结论 ADHD-ATs患儿较一般ADHD患儿的多动核心症状更为明显,执行功能上受损也更为严重。     

SNAP-Ⅳ评定量表与视听整合连续测试在评估注意缺陷多动障碍中的价值

目的:分析斯诺佩评估量表第四版(SNAP-Ⅳ)和视听整合连续测试(IVA-CPT)在注意缺陷多动障碍(ADHD)评估中的一致性和相关性,为诊断ADHD提供可靠的依据,降低ADHD诊断的误诊率和漏诊率。方法:收集2019年10月至2020年7月于温州医科大学附属第二医院育英儿童医院儿童康复科就诊的ADHD待确诊患儿的评估...     

听处理与学龄前儿童问题行为的关系：执行功能的中介作用

目的 探讨学龄前儿童听处理与问题行为的关系,并探究执行功能在其中的中介作用。方法 于2021年6—8月抽取南京2 342名7所幼儿园学龄前儿童,用《学龄前儿童听处理评估量表》《Conners父母问卷》《学龄前儿童执行功能行为评定问卷》对学龄前儿童进行评估,分析不同人口学特征儿童听处理、问题行为、执行功能的得分以及异常检出率的差异,同时采用多元线性回归分析影响儿童听处理总分、问题行为总分、执行功能总分的影响因素,并探究执行功能是否是听处理和执行功能的中介因素。结果 性别、年级是听处理总分的影响因素(P<0.05);性别、年级、父母受教育程度及家庭经济状况是问题行为总分、执行功能总分的影响因素(P<0.05)。听处理总分(rs=0.458,P<0.05)、问题行为总分(rs=0.185,P<0.05)与执行功能总分呈显著正相关,听处理总分与问题行为总分呈显著正相关(rs=0.423,P<0.05)。执行功能在听处理与问题行为间起部分中介作用,中介效应占总效应的33.44%。结论 学龄前儿童听处理可能直接影响其问题行为,也可能通过间接影响执行功能影响问题行为。[...     

睡眠质量对注意缺陷多动障碍儿童症状的影响:工作记忆的中介作用北大核心CSCD

目的探讨注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)儿童工作记忆在睡眠质量与症状之间的中介作用。方法采用随机整群抽样法从新疆维吾尔自治区喀什市2所小学3~5年级学生中筛选出符合条件的ADHD儿童(110例)及正常对照儿童(124例)为研究对象,采用SNAP-Ⅳ评估量表、匹兹堡睡眠质量指数量表(Pittsburgh Sleep Quality Index,PSQI)、工作记忆任务测试进行调查并比较。结果ADHD组儿童主观睡眠质量、入睡时间、睡眠效率、睡眠障碍评分及PSQI总分高于正常对照组(P<0.001),睡眠质量问题的发生率也高于正常对照组(P<0.001);ADHD儿童工作记忆得分低于正常对照组(P<0.001)。ADHD组工作记忆得分与PSQI总分呈负相关(r_(s)=-0.271,P<0.001),与症状得分呈负相关(r_(s)=-0.439,P<0.001);ADHD组PSQI总分与症状得分呈正相关(r_(s)=0.540,P<0.001)。工作记忆在睡眠质量对ADHD儿童症状影响中起部分中介效应,占总效应的18.10%。结论部分ADHD儿童存在睡眠质量问题,且工作记忆在ADHD儿童睡眠质量与症状之间起中介作用。     

情绪调节策略在注意缺陷多动障碍儿童症状与焦虑问题之间的中介作用

目的 探讨注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)儿童情绪调节策略在症状与其焦虑问题之间的中介作用。方法 采用便利整群抽样法从新疆维吾尔自治区喀什市10所小学10 211名在校生中筛选出符合条件的ADHD共435例为研究对象,采用SNAP-Ⅳ评估量表、儿童青少年情绪调节问卷、Conners父母症状问卷进行调查,采用Spearman秩相关分析、有调节的中介法分析数据。结果 ADHD儿童认知重评策略得分与症状得分、焦虑问题得分呈负相关(分别rs=-0.254、-0.270,P<0.001),症状得分与焦虑问题得分呈正相关(rs=0.329,P<0.001)。中介效应分析结果显示,认知重评策略在症状与焦虑问题中起部分中介效应,95%置信区间为0.008～0.027,中介效应占总效应的16.10%;同时性别在该中介模型中起调节作用(P<0.001)。结论 ADHD儿童认知重评策略在ADHD儿童症状与焦虑问题之间起中介作用,同时性别调节了ADHD患儿症状与认知重评策略、焦虑问题的关系。     

学龄期轻度孤独症谱系障碍儿童注意力特征分析

目的 探讨学龄期轻度孤独症谱系障碍 （ASD）儿童的注意力特征,为临床治疗提供依据。方法 收集学龄期轻度ASD儿童20例,使用整合视听持续性操作测试 （IVA-CPT）进行注意力评估。选取20名注意缺陷多动障碍 （ADHD）儿童和40名正常儿童作为对照。结果 与正常对照组比较,ASD组的综合注意、综合控制、视/ 听觉综合控制力、视/听觉谨慎、听觉毅力、视觉一致性、视/听觉警醒、视觉注意力、视觉速度商数,视/听觉正确反应数和视觉二、三阶段平均反应时得分低 （P <0.05）。与ADHD组比,ASD 组的综合控制力、听觉一致性、商数得分高 （P <0.05）,而视觉警醒、视觉速度商数得分低 （P <0.05）。结论 学龄期轻度ASD儿童存在注意缺陷,以注意集中能力缺陷为主且与ADHD 儿童受损相当,而注意控制能力受损相对较轻且优于ADHD儿童;视觉注意集中能力缺陷重于听觉,而视/听觉注意控制能力缺陷无明显差别。     

注意缺陷多动障碍儿童焦虑抑郁情绪研究

目的探讨注意缺陷多动障碍(ADHD)儿童情绪问题。方法ADHD儿童70例与对照组儿童45例分别自行完成儿童焦虑性情绪障碍筛查表、儿童抑郁障碍自评量表。结果ADHD组儿童躯体化/惊恐、广泛性焦虑、分离性焦虑、学校恐怖及焦虑、抑郁总分均高于对照组(P均<0.05)。结论ADHD组儿童存在明显焦虑、抑郁情绪。     

Parent SNAP-IV rating of attention-deficit/hyperactivity disorder: accuracy in a clinical sample of ADHD,validity, and reliability in a Brazilian sample

ObjectiveTo investigate the psychometric properties of the short or multimodal treatment study version of the Swanson, Nolan, and Pelham, Version IV (SNAP-IV) scale, which measures attention-deficit/hyperactivity disorder and oppositional defiant disorder symptoms.MethodsParticipants were 765 parents of children from 4 to 16 years old (641 non-attention-deficit/hyperactivity disorder and 124 attention-deficit/hyperactivity disorder children) from Belo Horizonte, Brazil, who reported sociodemographic characteristics and answered the SNAP-IV. Parents of the clinical sample also underwent the K-SADS-PL interview.ResultsAge was significantly associated with SNAP-IV hyperactivity-impulsivity problems (r = ?0.14), but not with inattention or oppositional defiant disorder. Sex was a significant influence on attention-deficit/hyperactivity disorder and oppositional defiant disorder severity (all p < 0.001), with boys showing higher scores in the full sample, but not within the attention-deficit/hyperactivity disorder group. Exploratory and confirmatory factor analysis supports a three-factor structure of the SNAP-IV scale. Moderate-to-strong correlations were found between SNAP-IV and K-SADS-PL measures. All SNAP-IV scales showed very high internal consistency coefficients (all above 0.91). SNAP-IV inattention scores were the most predictive of attention-deficit/hyperactivity disorder diagnosis (AUC: 0.877 for the averaging rating method and the raw sum method, and 0.874 for the symptom presence/absence method).ConclusionThe parent SNAP-IV showed good psychometric properties in a Brazilian school and clinical sample.
     

Game‐based peripheral biofeedback for stress assessment in children

Background: Peripheral biofeedback is considered to be an efficient method for assessment and stress mitigation in children. The aim of the present study was to assess the levels of stress and stress mitigation in healthy school children (HSC), in children with cystic fibrosis (CF), general anxiety (GA) and attention‐deficit–hyperactivity disorder (ADHD). Methods: Each investigated group (HSC, CF, GA, ADHD) consisted of 30 school‐aged children from both sexes. Psychological characteristics were evaluated on Eysenck Personality Questionnaire (EPQ). The lie scale was used to determine participant honesty. Four biofeedback games using a pulls detector were applied for assessment of the stress levels as well as to evaluate ability to relax. Results: EPQ found more psychopathological traits (P < 0.001) and less extroversion (P < 0.001) in children with GA and ADHD. In addition, high neurotic tendencies were found in children with CF (P < 0.01) and GA (P < 0.01). Unexpectedly, the lie scale was lower in ADHD children (P < 0.01) than in all other groups (HSC, CF, GA). The Magic blocks score was significantly different in relaxation levels between control and CF children (P < 0.05). Speed in the game Canal was significantly different in relaxation levels between healthy controls and all other groups, but no changes in pulls, as a relaxation measure, were found during the game. The CF group had much more commissions stemming from impulsivity (t= 5.71, P < 0.01), while the GA and ADHD children had more inattention omissions (P < 0.05). Strong negative correlation between age and pulls (r= 0.49, P= 0.003) and strong negative correlation between age and omissions (r=?0.86, P= 0.029) were found among all groups analyzed. Conclusions: The ability to learn stress mediation is correlated with age. All three groups of children had significantly lower relaxation levels when compared to healthy controls. Relaxation was more difficult for children with GA or ADHD, and easier for children with CF.     

胰石蛋白对脓毒症患儿病情评估的价值

目的 探讨胰石蛋白(PSP/reg)判断脓毒症患儿病情及预后的价值。方法 采用前瞻性病例对照研究,收集159例脓毒症患儿(脓毒症组106例;严重脓毒症组53例,其中脓毒性休克12例)及同期20例非脓毒症患儿(对照组)的临床资料,采用ELISA检测患儿入住PICU后第1、3、7天血浆PSP/reg浓度。血浆PSP/reg水平与血清降钙素原(PCT)、CRP、WBC计数、小儿危重病例评分(PCIS)的相关性进行Spearman相关分析,并采用受试者工作特征曲线下面积(AUC)评估各指标判断脓毒症患儿病情严重程度及预后的价值。结果 脓毒症组、严重脓毒症组入住PICU后第1天血浆PSP/reg水平高于对照组(PPn=27)入住PICU后第1天血浆PSP/reg水平高于存活患儿(n=132)(Prs=0.212、0.548;Prs=-0.373,PP结论 PSP/reg与感染密切相关,对脓毒症危险分层及预后评估有一定的临床价值。     

La escala pediátrica de evaluación del fallo multiorgánico secuencial (pSOFA): una nueva escala de predicción de la mortalidad en la unidad de cuidados intensivos pediátricos

ObjectivesTo assess performance of the age-adapted SOFA score in children admitted into Paediatric Intensive Care Units (PICUs) and whether the SOFA score can compete with the systemic inflammatory response syndrome (SIRS) in diagnosing sepsis, as recommended in the Sepsis-3 consensus definitions.MethodsTwo-centre prospective observational study in 281 children admitted to the PICU. We calculated the SOFA, Pediatric Risk of Mortality (PRISM), and Pediatric Index of Mortality-2 (PIM2) scores and assessed for the presence of SIRS at admission. The primary outcome was 30-day mortality.ResultsThe SOFA score was higher in nonsurvivors (P<.001) and mortality increased progressively across patient subgroups from lower to higher SOFA scores. The receiver operating characteristic (ROC) curve analysis revealed that the area under the curve (AUC) of the SOFA score for predicting 30-day mortality was 0.89, compared to AUCs of 0.84 and 0.79 for the PRISM and PIM2 scores, respectively. The AUC of the SOFA score for predicting a prolonged stay in the PICU was 0.67. The SOFA score was correlated to the PRISM score (r_s=0.59) and the PIM2 score (r_s=0.51). In children with infection, the AUC of the SOFA score for predicting mortality was 0.87 compared to an AUC of 0.60 using SIRS. The diagnosis of sepsis applying a SOFA cutoff of 3 points predicted mortality better than both the SIRS and the SOFA cutoff of 2 points recommended by the Sepsis-3 consensus.ConclusionsThe SOFA score at admission is useful for predicting outcomes in the general PICU population and is more accurate than SIRS for definition of paediatric sepsis.     

Pediatric Caregiver Version of the Shared Decision Making Process Scale: Validity and Reliability for ADHD Treatment Decisions

ObjectiveShared decision making (SDM) is recommended for common pediatric conditions; however, there are limited data on measures of SDM in pediatrics. This study adapted the SDM Process scale and examined validity and reliability of the scale for attention-deficit/hyperactivity disorder (ADHD) treatment decisions.MethodsCross-sectional survey of caregivers (n = 498) of children (aged 5–13) diagnosed with ADHD, who had made a decision about ADHD medication in the last 2 years. Surveys included the adapted SDM Process scale (scores range 0–4, higher scores indicate more SDM), decisional conflict, decision regret, and decision involvement. Validity was assessed by testing hypothesized relationships between these constructs. A subset of participants was surveyed a week later to assess retest reliability.ResultsPediatric Caregiver version of the SDM Process scale (M = 2.8, SD = 1.05) showed no evidence of floor or ceiling effects. The scale was found to be acceptable (<1% missing data) and reliable (intraclass correlation coefficient = 0.74). Scores demonstrated convergent validity, as they were higher for those without decisional conflict than those with decisional conflict (2.93 vs 2.46, P < .001, d = 0.46), and higher for caregivers who stated they made the decision with the provider than those who made the decision themselves (3.0 vs 2.7; P = .003). Higher scores were related to less regret (r = ?0.15, P < .001), though the magnitude of the relationship was small.ConclusionsThe adapted Pediatric Caregiver version of the SDM Process scale demonstrated acceptability, validity and reliability in the context of ADHD medication decisions made by caregivers of children 5–13. Scores indicate pediatricians generally involve caregivers in decision making about ADHD medication.     

Serum vascular endothelial growth factor: a new predictive indicator for the occurrence of coronary artery lesions in Kawasaki disease

We investigated serum vascular endothelial growth factor (SVEGF) levels in Kawasaki disease and determined whether these levels had any association with the development of coronary artery lesions. We measured SVEGF levels in 66 patients with Kawasaki disease, 18 patients with active infections and 18 afebrile controls. SVEGF levels of patients in the acute phase of Kawasaki disease (0.0–2003.6 pg/ml, median 59.87 pg/ml) were significantly higher than those of patients with active infections (0.0–45.2 pg/ml, median 8.10 pg/ml; P < 0.05) or afebrile controls (0.0–49.8 pg/ml, median 7.75 pg/ml; P < 0.05) and decreased to undetectable or low levels in the recovery phase (n=31, acute phase: 0.0–2003.6 pg/ml, median 62.50 pg/ml versus recovery phase: 0.0–146.5 pg/ml, median 26.90 pg/ml; P=0.0007) of the disease. There existed a positive correlation between SVEGF levels and serum C-reactive protein concentrations in the acute phase of Kawasaki disease (r _s =0.347, P=0.0051). In addition, SVEGF level and duration of fever were found to be major risk factors for the occurrence of coronary artery lesions by univariate (P=0.012 and P=0.003, respectively) and multivariate (P=0.037, OR 6.16 and P=0.0059, OR 7.59, respectively) analyses. Conclusion Serum vascular endothelial growth factor level, in combination with persistence of fever, could be a powerful predictor for the development of coronary aneurysms. Received: 16 March 1999 / Accepted: 30 November 1999     

Effects of a low-calorie diet on resting metabolic rate and serum tri-iodothyronine levels in obese children

The purpose of the study was to examine the effects of weight loss on resting metabolic rate (RMR) and on serum T3 levels in obese children and to investigate whether RMR changes are related to T3 changes. Sixty-four healthy, overweight, children (age: 12.1 ± 1.1 years, body mass index 29.3 ± 4.3 kg/m²) were studied during a 6-week weight reduction programme. RMR (by indirect calorimetry) total T3, total T4, TSH and fat-free mass (FFM) (by anthropometry) were measured at baseline and after 6 weeks of dietary treatment. Weight loss resulted in a 10.1% decline in RMR (P < 0.01) and a 23.4% decrease in serum T3 levels (P < 0.001). RMR was correlated with FFM before (r = 0.78, P < 0.001) and after weight loss (r = 0.76, P < 0.001). The changes in RMR were positively correlated with the changes in FFM (r = 0.48, P < 0.05) but also with the changes in serum T3 levels (r = 0.47, P < 0.05). The initial T3 levels predicted the subsequent fall in T3 that occurred after 6 weeks of dietary treatment (r = −0.60, P < 0.001). Conclusions A significant decrease in serum T3 concentrations and resting metabolic rate occurred as a result of a 6-week weight reduction programme in an obese child population. The decline in T3 levels combined with fat-free mass loss could be responsible for the reduction in resting metabolic rate. Received: 30 June 1998 / Accepted in revised form: 22 October 1998     

肺炎患儿支气管肺泡灌洗液中肺表面活性蛋白A和D表达及其与肺炎临床特征的相关性

目的 观察肺表面活性蛋白A、D(SP-A、SP-D)在肺炎患儿支气管肺泡灌洗液(BALF)中的表达,探讨SP-A、SP-D与肺炎患儿临床特征的相关性。方法 35例肺炎患儿纳入研究,对其肺泡灌洗液细胞进行分类计数,采用酶联免疫吸附试验(ELISA)检测患儿BALF中SP-A和SP-D水平。结果 患儿BALF中SP-D水平显著高于SP-A水平(Prs=-0.5255,P8mg/L)的患儿BALF中SP-D水平明显低于C反应蛋白正常的患儿(PPP>0.05)。结论 肺炎患儿BALF中SP-D的表达显著高于SP-A,与肺炎患儿的临床特征有一定相关性,作为一种保护性因子在调节免疫及炎症反应中发挥着比SP-A更重要的作用。     

Craniofacial differences according to AHI scores of children with obstructive sleep apnoea syndrome: cephalometric study in 39 patients

Background Cephalometry is useful as a screening test for anatomical abnormalities in patients with obstructive sleep apnoea syndrome (OSAS).Objective To evaluate comprehensively the cephalo metric features of children with OSAS, with or without adenotonsillar hypertrophy, and to elucidate the relationship between cephalometric variables and apnoea-hypopnoea index (AHI) severity.Materials and methods The study population consisted of 39 children, aged 4–12 years, with OSAS. Cephalometry was analysed using 11 measurements of the bony structures, their relationships and the size of the airways. Additionally, adenoid and tonsillar hypertrophy were graded.Results Cranial base angles (BaSN and BaSPNS) were found to correlate with increasing levels of AHI scores (P<0.001). Protrusion of the maxilla (SNA) and mandible (SNB) did not correlate with AHI scores (P>0.05). The length of the mandibular plane (GnGo) and the minimal posterior airway space (MPAS) were inversely correlated with AHI scores (P<0.001). There was positive correlation between MPAS and GnGo (r=0.740, P<0.001), and negative correlation between MPAS and gonial angle (ArGoGn) (r=–0.541, P<0.001). There was significant correlation between cephalometric data and adenotonsillar hypertrophy concerning BaSN, BaSPNS, ArGoGn, GnGoH, BaN-GnGo, MPAS, GnGO and MPH (P<0.001).Conclusions There is significant correlation between cephalometric data and AHI score severity in children with OSAS. Adenotonsillar hypertrophy affects the cephalometric measurements adversely. The study clearly mandates the institution of early and effective therapy of adenotonsillar hypertrophy in children with OSAS.