Analysis of Clincal Effects on 211 Cases with Middle and Late Stage Lung Cancer

ＡｎａｌｙｓｉｓｏｆＣｌｉｎｃａｌＥｆｆｅｃｔｓｏｎ２１１ＣａｓｅｓｗｉｔｈＭｉｄｄｌｅａｎｄＬａｔｅＳｔａｇｅＬｕｎｇＣａｎｃｅｒＡｎａｌｙｓｉｓｏｆＣｌｉｎｃａｌＥｆｆｅｃｔｓｏｎ２１１ＣａｓｅｓｗｉｔｈＭｉｄｄｌｅａｎｄＬａｔｅＳｔａｇｅＬｕｎ...     

Effect of Semen Persicae Extract Combined with Cultured Cordyceps on Reversing Capillarization of Sinusidsin patients with Hepato-Cirrhosis

Ｅｆｆｅｃｔ　ｏｆ　Ｓｅｍｅｎ　Ｐｅｒｓｉｃａｅ　Ｅｘｔｒａｃｔ　Ｃｏｍｂｉｎｅｄ　ｗｉｔｈ　Ｃｕｌｔｕｒｅｄ　Ｃｏｒｄｙｃｅｐｓ　ｏｎ　Ｒｅｖｅｒｓｉｎｇ　Ｃａｐｉｌｌａｒｉｚａｔｉｏｎ　ｏｆ　Ｓｉｎｕｓｏｉｄｓ　Ｉｎ　Ｐａｔｉｅｎｔｓ　ｗｉｔｈ　...     

Objectified Study of Abdomen Diagnosis on Blood Stasis Syndrome

ＯｂｊｅｃｔｉｆｉｅｄＳｔｕｄｙｏｆＡｂｄｏｍｅｎＤｉｓｇｎｏｓｉｓｏｎＢｌｏｏｄＳｔａｓｉｓＳｙｎｄｒｏｍｅ￥ＷＡＮＧＪｉｅ；ＣＨＥＮＫｅ－ｊｉ；ＳＯＮＧＸｉａｏ－ｈｕａ（ＸｉｙｕａｎＨｏｓｐｉｔａｌ，ＣｈｉｎａＡｃａｄｅｍｙｏｆＴＣＭ，Ｂｅｉｊｉ...     

Analysis of Therapeutic Effects on 72 Cases of Acute High Altitude Cerebral Edema Treated on the Spot In High Altitude Region

ＡｎａｌｙｓｉｓｏｆＴｈｅｒａｐｅｕｔｉｃＥｆｆｅｃｔｓｏｎ７２ＣａｓｅｓｏｆＡｃｕｔｅＨｉｇｈＡｌｔｉｔｕｄｅＣｅｒｅｂｒａｌＥｄｅｍａＴｒｅａｔｅｄｏｎｔｈｅＳｐｏｔＩｎＨｉｇｈＡｌｔｉｔｕｄｅＲｅｇｉｏｎｓＹａｎｇＪｉｎｇｙｉ（杨景义）ａｎｄＺ...     

Experimental Study on Effect of Cordyceps Sinensis in Ameliorating Aminoglycoside Induced Nephrotoxicity

Ｅｘｐｅｒｉｍｅｎｔａｌ　Ｓｔｕｄｙ　ｏｎ　Ｅｆｆｅｃｔ　ｏｆ　Ｃｏｒｄｙｃｅｐｓ　Ｓｉｎｅｎｓｉｓ　ｉｎ　Ａｍｅｌｉｏｒａｔｉｎｇ　Ａｍｉｎｏｇｌｙｃｏｓｉｄｅ　Ｉｎｄｕｃｅｄ　ＮｅｐｈｒｏｔｏｘｉｃｉｔｙＬＩＬｅｉ－ｓｈｉ；ＺＨＥＮＧＦｅｎｇ；Ｌ...     

Studies on the Anti-atherosclerosis Effects of Rhubarb and Salvia Miltiorrhiza

Ｓｔｕｄｉｅｓ　ｏｎ　ｔｈｅ　Ａｎｔｉ－ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ　Ｅｆｆｅｃｔｓ　ｏｆ　Ｒｈｕｂａｒｂ　ａｎｄ　Ｓａｌｖｉａ　ＭｉｌｔｉｏｒｒｈｉｚａＦａｎＬｅｍｉｎｇ（范乐明）ＪｉａｎｇＣｈｕａｎｇｃｈａｎｇ（姜传昌）ＣｈｅｎＹｕｈｕａ（陈毓...     

Effect of Salvia Miltiorrhizae Composita on Erythrocyte Membrane Phospholipid in Patients with Coronary heart Disease

Ｅｆｆｅｃｔ　ｏｆ　Ｓａｌｖｉａ　Ｍｉｌｔｉｏｒｒｈｉｚａｅ　Ｃｏｍｐｏｓｉｔａ　ｏｎ　Ｅｒｙｔｈｒｏｃｙｔｅ　Ｍｅｍｂｒａｎｅ　Ｐｈｏｓｐｈｏｌｉｐｉｄ　ｉｎ　Ｐａｔｉｅｎｔｓ　ｗｉｔｈ　Ｃｏｒｏｎａｒｙ　Ｈｅａｒｔ　ＤｉｓｅａｓｅＷＥＩＸｉａｏ－...     

Effects of Angelicae Sinensis on Oxygen Free Radicals and Proslaglandinsin Patiente of Chronic Pulmonary Heart Disease

ＥｆｆｅｃｔｓｏｆＡｎｇｅｌｉｃａｅＳｉｎｅｎｓｉｓｏｎＯｘｙｇｅｎＦｒｅｅＲａｄｉｃａｌｓａｎｄＰｒｏｓｌａｇｌａｎｄｉｎｓｉｎＰａｔｉｅｎｔｅｏｆＣｈｒｏｎｉｃＰｕｌｍｏｎａｒｙＨｅａｒｔＤｉｓｅａｓｅＸｕＪｕｎ－ｙａｎｇ（许军阳）；ＺｈｏｕＺｈ...     

Therapeutic Effects of Herbs Activating Blood Circulation and Dispersing Stasis on Acute Lung Injury after Abdominal Operations

Ｔｈｅｒａｐｅｕｔｉｃ　Ｅｆｆｅｃｔｓ　ｏｆ　Ｈｅｒｂｓ　Ａｃｔｉｖａｔｉｎｇ　Ｂｌｏｏｄ　Ｃｉｒｃｕｌａｔｉｏｎ　ａｎｄ　Ｄｉｓｐｅｒｓｉｎｇ　Ｓｔａｓｉｓ　ｏｎ　Ａｃｕｔｅ　Ｌｕｎｇ　Ｉｎｊｕｒｙ　ａｆｔｅｒ　Ａｂｄｏｍｉｎａｌ　Ｏｐｅｒａｔｉｏ...     

Effects and Interactions of Prostaglandins and Interferon－γ on Steroidogenesis ofHuman Luteal Cells

ＥｆｆｅｃｔｓａｎｄＩｎｔｅｒａｃｔｉｏｎｓｏｆＰｒｏｓｔａｇｌａｎｄｉｎｓａｎｄＩｎｔｅｒｆｅｒｏｎ－γｏｎＳｔｅｒｏｉｄｏｇｅｎｅｓｉｓｏｆＨｕｍａｎＬｕｔｅａｌＣｅｌｌｓＷａｎｇＨａｎ－ｚｈｅｎｇ（王寒正），ＳｈｅｎｇＷｅｉ－ｘｉｏｎｇ（沈维雄...     

Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients

Objective: To explore the protective effect of Baoyuan Qiangshen Capsule No. II (BYQS) and its mechanism in treating chronic renal failure (CRF).Methods: Sixty CRF patients were divided into 2 groups randomly, the treated group used BYQS combined with Lotensin and the control group administered with essential amino acid combined with Lotensin. Changes of renal functions and tubular labelled proteins were observed.Results: The markedly effective rate and total effective rate of the treated group were 63.3% and 93.3% respectively, and those of the control group were 30.0% and 56.7% respectively, the effect of the treated group was obviously better than that of the control group (P < 0.01). In the treated group after medication, blood urea nitrogen, serum creatinine and clearance rate of creatinine were improved significantly (P < 0.01), while Tamm-Horfau protein increased significantly (P < 0.01).Conclusion: BYQS could alleviate tubular interstitial injury significantly so as to improve the renal function and enhance the effective rate in treating CRF.     

Bailong tablet and chemotherapy in the treatment of moderate and advanced cancersand chemotherapy in the treatment of moderate and advanced cancers

Objective: To determine the effectiveness of Bailong Tablet and chemotherapy on treatment of moderate and advanced cancers.Methods: The patients were divided randomly into two groups. The treated group (n= 41) was treated with chemotherapy plus Bailong Tablet; and the control group (n= 22) treated with chemotherapy alone. Treatment effectiveness was measured with Karnofsky scores.Results: Karnofsky performance status in the treated group before and after treatment was 66.0 ± 8.7 and 68.0 ± 5.9 respectively, that in the control group was 67. 0 ± 6.8 and 53. 0 ± 7.3 respectively. The completion rate of chemotherapy in the treated group (92.6%, 38/41) was higher than that in control (77.2%, 17/22,P < 0.05). The side-effects caused by chemotherapy in the treated group were lower than that in the control group (P < 0.05). CD₃ ⁺, CD₄ ⁺ and CD₄ ⁺ /CD₈ ⁺ ratio were higher in the treated group.Conclusion: Bailong Tablet can enhance the therapeutic effect and reduce the side-effects of chemotherapy. One possible mechanism is the modulation of cellular immune function.     

Effect of Zhuchun Pill on immunity and endocrine function of senile Kidney-Yang Deficiency) on immunity and endocrine function of senile Kidney-Yang Deficiency

Objective: To evaluate the effect of Zhuchun pill (ZCP) on senile Kidney-Yang Deficiency (KYD).Methods: By single blind method, 45 elderly males with KYD were divided randomly into the ZCP group (treated by ZCP) and the control group (treated by placebo, starch capsule) and treated for 3 months.Results: ZCP could greatly improve the main symptoms of KYD,P < 0. 01 in comparison with the control group. After treatment, in the ZCP group, the³H-TdR lymphocyte transformation rate, levels of serum C₃, IgA, IgD, IgG and IgM, superoxide dismutase, plasma adrenocortical hormone, testosterone and cyclic adenosine monophosphate all increased,P < 0.01, and plasma lipid peroxide decreased,P < 0.01. While in the control group, no remarkable change was found in these parameters.Conclusion: ZCP could improve the KYD through regulating the immunity, endocrine function and scavenging the free radicals in organism.     

Protective effect of Shengmai Injection on rats with contrast medium-associated acute renal failure) on rats with contrast medium-associated acute renal failure

Objective: Radiographic contrast media can induce renal failure and it may serve as an experimental model of acute renal failure (ARF). The study was aimed to determine the protective effect of Shengmai Injection (SMI) on contrast medium-associated ARF in Sprague-Dawley (SD) rats.Methods: Twenty healthy SD rats of both sex were randomly divided into two groups, Group A (control group) treated with glycerin+0. 9% saline+meglucamine diatrizoate, and group B (preventive group) with glycerin+SMI+meglucamine diatrizoate.Results: In Group B, the levels of blood urea nitrogen, serum creatinine, renal phospholipase A₂ (PLA₂) and calcium were all significantly lower than those in Group A,P < 0.01. The results indicated the renal injury induced by meglucamine diatrizoate was alleviated by SMI.Conclusion: SMI could prevent renal tissue from contrast media induced nephropathy in SD rats. The effect may partially owe to its preventing intracellular calcium accumulation, inhibiting PLA₂ activity and dilating renal vessels.     

Studies on Nutritional Effects of Traditional Chinese Tonics with Nutrients Fortification on Pregnantrats

Ｓｔｕｄｉｅｓ　ｏｎ　Ｎｕｔｒｉｔｉｏｎａｌ　Ｅｆｆｅｃｔｓ　ｏｆ　Ｔｒａｄｉｔｉｏｎａｌ　Ｃｈｉｎｅｓｅ　Ｔｏｎｉｃｓ　ｗｉｔｈ　Ｎｕｔｒｉｅｎｔｓ　Ｆｏｒｔｉｆｉｃａｔｉｏｎ　ｏｎ　Ｐｒｅｇｎａｎｔ　Ｗｏｍｅｎ　ａｎｄ　Ｐｒｅｇｎａｎｔ　Ｒａｔｓ...     

Effect of Reduqing on plasma lnterleukin-8 and nitric oxide in rabbits with endotoxin induced disseminated intravascular coagulation

Objective: To investigate the effects of Reduqing (RDQ, ) on plasma interleukin-8 (IL-8), NO₂ ^- /NO₃ ^-, complement 5a (C_5a) and polymorphonuclear neutrophilic leukocyte (PMN) chemotaxis Index (CI) in rabbits with endotoxin-induced disseminated intravascular coagulation (DIC).Methods: Endotoxin-in-duced DIC model made by injection of Lipopolysacchrides (LPS) was used in the experiment. Above-mentioned indexes were determined before and after RDQ treatment and compared with blank and dexamethasone treated group.Results: Plasma IL-8, NO₂ ^- /NO₃ ^-, C_5a and CI level of PMN increased markedly in the model group, which were confirmed pathologically with obvious damage of tissues or organs. In the RDQ group, the abovem entiond parameters and damage of tissues or organs were reduced significantly (P < 0.01).Conclusion: IL-8 and NO might be involved in pathogenesis of endotoxin-induced DIC, and RDQ could be used in preventing or treating DIC through the mechanism of regulation of cytokines network.     

The MEDIGATE Graphical User Interface for Entry of Physical Findings: Design Principles and Implementation

The solution to many of the problems of the computer-based recording of the medical record has been elusive, largely due to difficulties in the capture of those data elements that comprise the records of the Present Illness and of the Physical Findings. Reliable input of data has proven to be more complex than originally envisioned by early work in the field. This has led to more research and development into better data collection protocols and easy to use human-computer interfaces as support tools. The M edical E xamination D irect I conic and G raphic A ugmented T ext E ntry S ystem (MEDIGATE System) is a computer enhanced interactive graphic and textual record of the findings from physical examinations designed to provide ease of user input and to support organization and processing of the data characterizing these findings. ^(27,30) The primary design objective of the MEDIGATE System is to develop and evaluate different interface designs for recording observations from the physical examination in an attempt to overcome some of the deficiencies in this major component of the individual record of health and illness.     

Clinical observation on patients with endometriosis treated by tonifying Kidney and removing blood stasis

Endometriosisisacommonlyandfrequentlyencounteredgynecologicaldisease.FollowingthetheoryoftraditionalChinesemedicine(TCM),'theKidneyisinchargeofreproduction",andi'theafterbirthandfetusareconnectedwiththeKidneyi',togetherwiththefollowingmanifestationsofendometriosis:dysmenorrhea,infertility,irregularmenstruation,dyspareunia,tinnitus,lassitudeintheloinandknees,hyposexuality,havingnodesandmasses,etc.,weholdthattheSyndromeDifferentiationforendometriosisshouldbe)'Kidneydeficiencyandbloodstasis"(l…     

Effect of Xueguantong on plasma endothelin and calcitonin gene-related peptide in quail atherosis modelon plasma endothelin and calcitonin gene-related peptide in quail atherosis model

Objective: To explore the antiatherogenic mechanism of the action of Xueguantong at molecular level.Methods: After being established by feeding with high fat diet for 12 weeks, the quail atherosis models were given Xueguantong for 30 days. Then, their plasma endothelin and calcitonin gene-related peptide (CGRP) were determined with radioimmunoassay (RIA) and the effects of Xueguantong on plasma endothelin and CGRP in the models were observed.Results: The plasma endothelin increased and CGRP decreased during quail atherosis formation. The plasma endothelin was decreased (P < 0.05) and CGRP increased (P < 0.05) by Xueguantong.Conclusion: One of antiatherogenic mechanisms of Xueguantong was decreasing endothelin and increasing CGRP.     

Clinical study on influence of Buyang Huanwu Decoction on the metabolic imbalance of endothelin and calcitonin gene related peptide in patients with early cerebral infarctionon the metabolic imbalance of endothelin and calcitonin gene related peptide in patients with early cerebral infarction

Objective: To explore the mechanism of Buyang Huanwu Decoction (BHD) in treating early cerebral infarction.Methods: Seventy cases with early cerebral infarction were randomly divided into two groups. Chinese medicine group (CMG, n = 35) was treated with BHD; western medicine group (WMG, n = 35) was treated with hydroxyethyl starch injection and enteric coated aspirin tablets. The levels of endothelin (ET) and calcitonin gene related peptide (CGRP) in plasma before and after treatment and the results of clinical treatment were observed. Also healthy subjects were used as the normal control.Results: The levels of ET before treatment in the two treated groups were significantly higher than that of the healthy subjects (P<0. 001), and the levels of CGRP were significantly lower (P < 0.001). After treatment the metabolic imbalance of ET and CGRP improved significantly in the two treated groups (P<0. 001), but the ET and CGRP in CMG improved more obviously than those in WMG (P<0.01, P<0.05). The markedly effective and curative rate of CMG was higher than that of WMG (68. 6 % vs 31.4 %; ?² = 9. 65, P < 0. 01).Conclusion: BHD could improve the metabolic imbalance of ET and CGRP in patients with early cerebral infarction and on the virtue of this mechanism it could be used to treat cerebral infarction.