经皮球囊扩张椎体后凸成形术治疗老年骨质疏松性椎体压缩性骨折

目的分析经皮球囊扩张椎体后凸成形术(PKP)治疗老年骨质疏松性椎体压缩性骨折的临床效果及安全性。方法对34例老年骨质疏松性椎体压缩性骨折患者实施PKP。观察患者术后疼痛、椎体恢复及并发症发生情况。结果本组34例患者术后发生骨水泥渗漏1例(2.94%)。未发生坠积性肺炎、肺栓塞、大小便失禁等其他并发症。术后随访6~10个月,术后7 d、6个月随访,患者椎体前缘高度、伤椎后凸角度、视觉模拟评分法(VAS)评分及Barthel指数等均优于术前,差异有统计学意义(P0.05)。结论 PKP治疗骨质疏松性椎体压缩性骨折,并发症少、疼痛缓解及伤椎恢复效果好,患者生活质量可得到明显提高。     

球囊后凸成形术治疗骨质疏松椎体压缩性骨折

[目的]探讨椎体球囊后凸成形术对骨质疏松椎体压缩性骨折的治疗效果。[方法]对2018年3月～2018年11月因椎体压缩性骨折至本院就诊、行"椎体球囊后凸成形术"的患者进行随访,记录其术前、术后的疼痛评分和功能评分并进行对比,评估其手术疗效。[结果]所有患者均顺利完成手术,手术时间平均(40.91±4.63) ml,术中出血量平均(31.83±6.04) ml,平均住院(2.41±0.62) d,未出现神经根损伤、大出血等术中并发症。术后患者VAS评分及ODI评分均明显降低,差异有统计学意义(P0.05)。随访3个月期间,所有患者均未出现骨水泥移位、骨水泥栓塞等并发症。1例患者术后1个月出现伤椎邻椎骨折,再次行椎体成形手术治疗。[结论]椎体球囊后凸成形术能够有效缓解椎体压缩性骨折患者的疼痛,提高生活质量。     

经皮球囊扩张椎体后凸成形术治疗 老年骨质疏松性椎体压缩性骨折

目的探讨经皮球囊扩张椎体后凸成形术（PKP)治疗老年骨质疏松性椎体压缩性骨折的临床 效果。方法对69例共叨个老年骨质疏松性椎体压缩性骨折的患者,均行经皮球囊扩张椎体后凸 成形术。观察指标为术前术后的疼痛视觉模拟评分（vasal analogue scale,VAS )、椎体高度的恢复及 并发症发生情况。结果 W个椎体均经皮行双侧椎弓根穿刺成功完成手术。所有患者疼痛缓解, VAS术前平均为（7. 52 10. 49)分,术后第3天平均为（2. 38 1 0. 22)分;术后1个月VAS平均为（1. 88 ±0. 12)分。术前骨折椎体前缘高度平均为（15.65 1 0. 68 ) mm,术后椎体前缘高度平均为（23.68 1 0.83) mm,术前术后差异有显著性（P < 0. 05 )。骨水泥注射量每个椎体3.5-7.5@1,平均5.5 ml。骨 水泥少量渗漏到椎间隙1个椎体,沿手术通道反流至椎弓根2个椎体,均无临床症状,渗漏率为 3.23%。结论经皮球囊扩张椎体后凸成形术（PKP)治疗老年骨质疏松性椎体压缩性骨折,能迅速 缓解疼痛,一定程度的恢复椎体高度,临床疗效确切。     

球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩性骨折

目的观察球囊扩张椎体后凸成形术(PKP)治疗骨质疏松性椎体压缩性骨折的临床疗效。方法采用PKP治疗60例骨质疏松性椎体压缩性骨折患者(共77椎),比较手术前后VAS评分、椎体前缘高度、Cobb角变化情况,分析疗效。结果 VAS评分术后低于术前,椎体前缘高度术后高于术前,Cobb角术后小于术前,差异均有统计学意义(P<0.05)。患者均获随访,时间6～12(8.2±1.7)个月。随访期间均未发生疼痛加重情况。结论 PKP治疗骨质疏松性椎体压缩性骨折临床疗效良好,有效恢复并保持脊柱功能,并发症少,患者接受程度较高。     

经皮椎体后凸成形术治疗老年骨质疏松性椎体压缩性骨折

目的 探讨经皮椎体后凸成形术(PKP)治疗老年骨质疏松性椎体压缩性骨折的临床疗效.方法 30例老年骨质疏松性椎体压缩骨折患者在C臂机引导下行PKP治疗,通过疼痛视觉模拟评分法(VAS),测量Cobb角及术前、术后和末次随访椎体高度等评价疗效.结果 所有手术均顺利完成,疼痛明显缓解,椎体高度无明显丢失,未出现严重骨水泥渗漏,无严重并发症发生;VAS由术前的7.7±1.0下降至术后的2.3±0.7,末次随访的2.4±0.6;Cobb角由术前的(29±5.4)°矫正到术后的(21±3.5)°,末次随访时的(22±3.6)°;椎体高度由术前的(12.9±2.6)mm到术后的(21.5±1.8)mm,末次随访时的(21.3±1.7)mm.术后与术前、末次随访与术前差异均有统计学意义(P<0.05),术后与末次随访差异无统计学意义(P＞0.05).结论 经皮椎体后凸成形术创伤小,安全性高,能有效缓解疼痛,矫正后凸畸形,是一种治疗老年骨质疏松性椎体压缩骨折安全有效的方法.     

经皮椎体成形术和经皮椎体后凸成形术治疗重度骨质疏松性椎体压缩性骨折疗效分析

目的 观察经皮椎体成形术( Percutaneous vertebroplasty,PVP)和经皮椎体后凸成形术(Percutanous kyphoplasty,PKP)治疗重度骨质疏松性椎体压缩骨折的临床疗效、可行性、安全性.方法回顾性分析2006年1月至2010年12月收治重度骨质疏松性椎体压缩骨折患者并获得随访34例,PVP治疗19例25个椎体,PKP治疗15例20个椎体.观察两组患者间SF-36评分、伤椎高度恢复、骨水泥渗漏及随访期间伤椎高度丢失情况、临近椎体骨折情况.结果 PVP组和PKP组患者在术中骨水泥渗漏率、末次随访时SF-36评分、末次随访时临近椎体骨折发生率间差异无统计学意义(P＞0.05).在椎体复位效果的观察指标上,PKP组术后椎体前缘间、椎体上下终板中心间高度恢复量、术后后凸角度恢复值、末次随访后凸角度恢复值上与PVP组间差异有统计学意义(P＜0.05),同时在末次随访时PKP组伤椎高度丢失量与PVP组差异也有统计学意义(P＜0.05).结论 PVP和PKP治疗重度骨质疏松性椎体压缩性骨折均可显著改善患者症状,PKP具有较好的复位效果,但术后椎体高度丢失明显,在骨水泥渗漏率、相邻椎体骨折发生率指标上相对于PVP未表现出明显优越性.     

经皮椎体后凸成形术治疗老年骨质疏松性椎体压缩性骨折

目的探讨经皮椎体后凸成形术(PKP)治疗老年骨质疏松性椎体压缩性骨折(OVCF)的临床疗效。方法对60例老年OVCF患者采用PKP治疗,手术在C臂机透视下进行。记录并比较术前、术后3 d、术后1年的视觉模拟疼痛评分(VAS)及病椎最大塌陷处的高度、Cobb角的变化。结果 60例均获得随访,时间1~3年,术后病椎疼痛症状均显著缓解。术后3 d和术后1年的VAS评分、病椎最大塌陷处的高度、Cobb角与术前比较差异均有统计学意义(P0.01)。结论 PKP治疗老年OVCF可以有效恢复椎体高度和矫正后凸畸形,迅速缓解疼痛,提高患者的生活质量。     

经皮球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩骨折

骨质疏松性胸腰椎压缩性骨折是老年人常见病,严重影响了生活质量。以往治疗方法为单纯采用俯卧背伸复位、佩戴矫形支具、理疗、止痛等姑息疗法。经皮球囊扩张椎体后凸成形术（percutaneous kyphoplasty,PKP）是近年来治疗胸腰椎骨质疏松性压缩骨折、椎体转移瘤等疾病引起疼痛的一项新型微创脊柱外科技术,被认为是理想的较为安全的选择。从2003年10月至2007年4月,应用球囊经皮椎体成形手术系统治疗椎体压缩骨折17例30椎,取得了良好效果,现总结如下。     

经皮椎体后凸成形术治疗胸腰段骨质疏松性椎体压缩性骨折

目的探讨经皮椎体后凸成形术治疗胸腰段骨质疏松性椎体压缩性骨折的临床疗效。方法对78例胸腰段骨质疏松性椎体压缩性骨折患者采用双侧椎弓根穿刺技术行经皮椎体后凸成形术,术后按序功能锻炼,系统抗骨质疏松治疗。结果 78例患者均获随访,术中无神经根和脊髓受压损伤,术后腰背部疼痛明显减轻或消失,术后视觉模拟评分法(VAS评分)、Cobb氏角、伤椎高度与术前比较差异有统计学意义(P0.05)。术后X片显示,骨水泥在椎体内呈点状和片状分布,椎体复张良好。按JOA评分:优56例,良14例,可4例,差4例。优良率为89.7%。结论经皮椎体后凸成形术治疗胸腰段骨质疏松性椎体压缩性骨折,可使伤椎骨质强化,增加稳定性,减轻疼痛。便于患者早期下床活动,提高生活质量,减少长期卧床并发症。     

经皮椎体后凸成形术治疗骨质疏松性胸腰椎骨折

目的探讨经皮椎体后凸成形术（PKP）治疗骨质疏松性胸腰椎体压缩性骨折的临床疗效。方法对59例患者的80个骨折椎体施行PKP,比较手术前后VAS评分、椎体高度、后凸Cobb角的变化,评估疗效。结果患者手术均成功,未发生脊髓、神经损伤。59例均获24个月的随访。术前、术后即刻、术后12个月、术后24个月的VAS值分别为6．06分±1．02分、2．45分±1．04分、2．80分±1．13分和2．90分±1．90分;后凸Cobb角度分别为24．62°±4．71°、21．71°±3．92°、22．20°±3．60°和22．90°±3．28°;椎体高度值分别为19．0mm±1．80him、26．3mm±2．10mm、25．9mm±2．00mm和24．2mm±2．03mE;术后各时段与术前比较3项差异均有统计学意义（P〈0．05）。术后即刻、12个月、24个月的治疗有效率分别为93．00％、81．72％、72．09％。结论PKP治疗骨质疏松性胸腰椎体压缩性骨折微创、安全,能迅速缓解疼痛,临床效果满意。     

球囊扩张椎体后凸成形术对骨质疏松压缩骨折止痛和椎体高度恢复的影响

目的 评价应用经皮球囊扩张椎体后凸成形术治疗对疼痛性胸腰椎骨质疏松压缩骨折止痛效果和对椎体高度恢复的影响.方法 应用球囊扩张椎体后凸成形术治疗胸腰椎骨质疏松压缩骨折患者45例85椎(T4-L4),年龄53～86岁(平均71岁),有症状的节段均做MRI证实.手术后当天和术后随访分别进行疼痛得分VAS(visual ana...     

Percutaneous balloon kyphoplasty of osteoporotic vertebral compression fractures with intravertebral cleft

Background:

Intravertebral cleft is a structural change in osteoporotic vertebral compression fractures (OVCF), which is the manifestation of ischemic vertebral osteonecrosis complicated with fracture nonunion and pseudoarthrosis and appears in the late stage of OVCF. Despite numerous studies on OVCF, few aim to evaluate the clinicoradiological characteristics and clinical significance of intravertebral cleft in OVCF. This study investigates clinicoradiological characteristics of intravertebral cleft in OVCF and the effect on the efficacy of percutaneous balloon kyphoplasty (PKP).

Materials and Methods:

PKP was performed on 139 OVCF patients without intravertebral cleft (group A) and 44 OVCF patients with intravertebral cleft (group B). The frequency distribution of the affected vertebral body, bone cement infusion volume, imaging manifestation, leakage rate and type, preoperative and postoperative height of the affected vertebral body, visual analog scale (VAS) and Oswestry disability index (ODI) score were evaluated.

Results:

Significant differences were found in the frequency distribution of the affected vertebral body and bone cement leakage type between the two groups (P < 0.05). However, differences in bone cement infusion volume and leakage rate (P > 0.05) were not detected. In both groups, the postoperative height of the affected vertebral body was significantly improved (P < 0.05). The restoration of vertebral body height in group B was more evident than that in group A (P < 0.05). The preoperative VAS and ODI scores in group B were significantly higher than those in group A (P < 0.05). After surgical treatment, pain relief and daily activity function in both groups were significantly improved (P < 0.05), and no significant difference in postoperative scores was detected between the two groups (P > 0.05).

Conclusion:

Intravertebral cleft exhibits specific clinical and imaging as well as bone cement formation characteristics. PKP can effectively restore the affected vertebral body height, alleviate pain, and improve daily activity function of patients.     

经皮球囊扩张后凸成形术治疗老年椎体压缩骨折的随访研究

[目的]探讨经皮球囊扩张后凸成形术治疗老年骨质疏松性椎体压缩骨折的手术效果和患者术后的生活质量.[方法]采用经皮球囊扩张后凸成形术治疗老年椎体压缩骨折病例105例.测量术前、术后3d、术后3个月和随访结束时的椎体高度;术前、术后3d、术后3个月和随访结束时对患者腰痛行VAS评分,术前、术后3个月和随访结束时对患者进行ODI评分.[结果]91例患者获随访,随访时间13 ～ 50个月,平均33.2个月.患者术前椎体平均高度为(1.45 ±0.28) cm,术后3d复查X线片测量的椎体平均高度为(1.75 ±0.23) cm,术后3个月时椎体平均高度(1.75±0.23) cm,随访结束时患者椎体平均高度为(1.74±0.24) cm.术前VAS评分为(7.53±0.68),术后3d为(2.69 ±0.49),术后3个月为(1.02±0.33),随访结束时为(1.01±0.39).术前ODI评分为(77.85 ±3.53),术后3个月为(28.67 ±5.85),随访结束时为(21.33±3.47).术前、术后的椎体高度,VAS评分,ODI评分差别有统计学意义(P＜0.01).[结论]经皮球囊扩张后凸成形术治疗老年骨质疏松性椎体压缩骨折能部分恢复椎体高度,针对压缩骨折带来的腰痛有良好的治疗效果,明显改善了患者的生活质量.     

椎体后凸成形术治疗580例老年性骨质疏松性椎体压缩性骨折疗效的影响因素分析

目的分析椎体后凸成形术(percutaneous kyphoplasty,PKP)治疗老年性骨质疏松性椎体压缩性骨折的疗效并探讨其影响疗效的因素。方法选择我院老年性骨质疏松性椎体压缩性骨折的580例患者行椎体后凸成形术,调取资料并记录与疗效相关的因素:年龄、性别、椎体压缩程度、楔形变角度、骨折椎体数量、骨折部位、单/双侧穿刺、骨水泥注入量、骨水泥椎间盘渗漏、规范抗骨质疏松治疗,并使用二分类Logistic回归探讨这些因素与疗效之间存在的关系。结果单变量因素分析椎体压缩程度[OR=2.68(2.03～3.24),P0.01]、骨折椎体数量[OR=3.54(2.87～4.12),P0.01]、骨折部位[OR=4.02(3.34～4.67),P0.01]、骨水泥注入量[OR=2.52(2.01～2.92),P0.05]、骨水泥椎间盘渗漏[OR=1.98(1.67～2.42),P0.01]、规范抗骨质疏松治疗[OR=2.70(2.31～3.22),P0.01]认为与术后疗效相关,进行多变量回归分析,经多变量Logistic回归分析(LR法),骨折椎体数量[OR=4.70(3.28～5.61),P=0.000]、骨水泥椎间盘渗漏[OR=5.12(2.07～8.26),P=0.000]、规范抗骨质疏松治疗[OR=4.40(2.93～6.71),P=0.000]与椎体后凸成形术后疗效显著相关。结论影响椎体后凸成形术疗效中,骨折椎体数量、骨水泥椎间盘渗漏、规范抗骨质疏松治疗较其他因素与疗效关系更密切。     

经皮椎体成形术治疗老年多节段椎体压缩性骨折疗效分析

目的观察分析经皮椎体成形术治疗老年多节段椎体压缩性骨折的疗效。方法 2010年2月～2011年2月在本科对14例2个节段、6例3个节段椎体压缩性骨折行经皮穿刺椎体成形术。所有的患者术前通过完善体格检查及辅助检查明确诊断。观察手术前及术后1 d视觉疼痛评分(VAS)评分、巴塞尔指数(BI)、病椎前中柱高度的变化,并随访6个月～1年。结果 VAS评分从术前(8.7±1.2)分降低至术后1 d(2.0±1.1)分(P<0.01);巴塞尔指数从术前(3.2±1.0)分降低至(1.5±0.9)分(P<0.05);病椎椎体前、中柱的平均高度分别由原来的(20.8±2.4)mm和(19.6±2.2)mm,恢复到(24.0±2.1)mm和(23.7±1.4)mm(P<0.05)。结论经皮椎体成形术治疗老年多节段椎体压缩性骨折安全、有效。     

经皮椎体后凸成形术治疗老年新鲜骨质疏松性椎体压缩骨折

目的探讨经皮椎体后凸成形术(PKP)治疗老年新鲜骨质疏松性椎体压缩骨折(OVCF)的临床疗效。方法采用PKP治疗86例老年新鲜OVCF患者,观察手术一般情况、术后并发症情况及疗效。结果患者均获得随访,时间1~3年。VAS评分、ODI、椎体后凸Cobb角、椎体前缘及中部高度变化等5项指标术后2 d及末次随访均较术前显著改善,差异均有统计学意义(P0.01,P0.05)。未出现骨水泥椎管内渗漏、神经或神经根损伤、肺栓塞等严重并发症。结论 PKP治疗老年新鲜OVCF疗效确切,手术出血量少,并发症少,术后患者症状和体征改善显著。     

Outcome of percutaneous balloon kyphoplasty in vertebral compression fractures

Background:Incidence of vertebral compression fractures (VCFs) is increasing due to increase in human life expectancy and prevalence of osteoporosis. Vertebroplasty had been traditional treatment for pain, but it neither attempts to restore vertebral body height nor eliminates spinal deformity and is associated with a high rate of cement leakage. Balloon kyphoplasty involves introduction of inflatable balloon into the fractured body of vertebra for elevation of the end-plates prior to fixation of the fracture with bone cement. This study evaluates short term functional and radiological outcomes of balloon kyphoplasty. The secondary aim is to explore short-term complications of the procedure.Results:Statistically significant improvements in SF-36 (from 34.29 to 48.53, an improvement of 14.24, standard deviation (SD) - 20.08 P < 0.0001), VAS (drop of 4.49, from 6.74 to 2.24, SD - 1.44, P < 0.0001), percentage restoration of lost vertebral height (from 30.62% to 16.19%, improvement of 14.43%, SD - 15.37, P < 0.0001) and kyphotic angle correction (from 17.41° to 10.59°, improvement of 6.82, SD - 7.26°, P < 0.0001) were noted postoperatively. Six patients had cement embolism, 65 had cement leak and three had adjacent level fracture which required repeat kyphoplasty later. One patient with history of ischemic heart disease had cardiac arrest during the procedure. No patients had neurological deterioration in the followup period.Conclusions:Kyphoplasty is a safe and effective treatment for VCFs. It improves physical function, reduces pain and corrects kyphotic deformity.     

Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for osteoporotic vertebral compression fracture: A metaanalysis

Background:Osteoporotic vertebral compression fracture (OVCF) is the most common complication of osteoporosis, however, debate persists over which procedure of percutaneous vertebroplasty (PVP) or balloon kyphoplasty (BKP) is a better treatment. We performed a metaanalysis of prospective, randomized controlled and clinical controlled trials of PVP and BKP to determine the efficacy and safety for the treatment of OVCFs to reach a relatively conclusive answer.Results:As of March 15, 2013, a PubMed search resulted in 761 articles, of which eleven studies encompassing 789 patients, met the inclusion criteria. The average length of followup is 17 months and 4.6% patients were lost to followup. Results of metaanalysis indicated that BKP is more effective for short term pain relief. In addition, BKP is more effective to restore the AVBH (anterior vertebral body height), ODI and kyphotic angle of OVCFs. Moreover, BKP need more polymethylmethacrylate amount.Conclusions:In terms of better effectiveness of BKP procedure, we believe BKP to be superior over PVP for the treatment of osteoporotic VCFs.