应变率成像定量分析心肌梗死患者PTCA术前后左心室局部舒缩功能

目的:采用应变率成像技术(SRI)定量观察心肌梗死患者PTCA术前后左室壁运动,探讨SRI技术在评价冠心病介入治疗疗效中的临床应用价值。方法:心梗组25例,正常对照组14例分别行常规超声心动图与彩色组织速度成像(TVI)检查。SRI测量参数:①收缩期峰值应变率(SRs);②舒张早期峰值应变率(SRe);③舒张晚期峰值应变率(SRa);④计算SRe/SRa。结果:PTCA术前,与对照组正常节段比较,心梗组运动异常节段SRs、SRe、SRe/SRa显著降低,运动正常节段SRs、SRe、SRe/SRa无显著变化;与运动正常节段比较,心梗组运动异常节段SRs、SRe、SRe/SRa显著降低。与PTCA术前比较,心梗组室壁运动改善节段SRs、SRe、SRe/SRa显著增加,室壁运动无改善节段SRs、SRe、SRe/SRa无显著改变。心梗组患者PTCA术前后二尖瓣口△E和所有室壁运动异常节段S△SRe呈显著正相关(r=0.63)。结论:SRI能准确检测出局部心肌功能异常及血运重建后心肌功能的恢复情况,可为临床评价冠脉血运重建术疗效提供准确敏感的量化指标。     

Echocardiography in the diagnosis of right ventricular endomyocardial fibrosis

Twenty-one patients with endomyocardial fibrosis (EMF) and right ventricular involvement were studied by M-mode echocardiography. All 21 patients showed echocardiographic findings consisting of (i) increased right ventricular dimension, (ii) paradoxical septal motion, (iii) increased right ventricular outflow dimension (iv) thickening of the right ventricular anterior wall with increased right ventricular anterior wall motion, and (v) easily recordable tricuspid valve. In addition, some of the patients had posterior pericardial effusion, and fine fluttering of the tricuspid valve. EMF was diagnosed clinically in all the patients, haemodynamically and angiographically in 15 and confirmed at autopsy in one.     

三维斑点追踪技术在评价急性心肌梗死经皮冠状动脉治疗术后近期左室壁运动和收缩功能中的应用及其价值

目的：利用实时三维斑点追踪技术（3D-STI）评价中老年急性心肌梗死患者经皮冠状动脉介入治疗术（PCI）后心肌各节段应变、左室整体应变及左心室整体收缩功能,阐明其PCI术后早期心肌应变改变特点及其临床价值。方法：选取因左前降支病变行PCI术患者30例作为病例组,同期选取健康中老年人30名作为对照组,常规获取二维超声资料后,运用3D-STI对2组受试者进行心肌运动及收缩功能检测,收集左心室各节段及整体纵向应变（GLS）、径向应变（GRS）、圆周应变（GCS）和面积应变（GAS）值以及左室射血分数（LVEF）值。结果：与对照组比较,病例组患者整体应变值低于对照组对应节段,各节段应变值中,病例组左心室9/16节段的纵向应变（LS）值减低,8/16节段的圆周应变（CS）值减低,5/16节段的径向应变（RS）值减低,11/16节段的面积应变（AS）值减低（P<0.05）;应变值减低节段主要集中于前壁基底段、前壁中间段、前壁心尖段、前间隔基底段、前间隔中间段、后间隔基底段、后间隔中间段、后间隔心尖段。病例组GLS、GAS和GCS与LVEF呈负相关关系（r=-0.819,r=-0.897,r=-0.807,P<0.0001）,GRS与LVEF呈正相关关系（r=0.862,P<0.0001）。结论：3D-STI能够定量分析AMI患者PCI术后早期左心室心肌应变及心功能的变化,可作为PCI术后疗效评估的客观指标。     

Cardiac disease in dialysis patients in a Jamaican hospital: echocardiographic findings that predict mortality

The aim of the study was to assess, by echocardiography, the cardiac abnormalities in a group of patients with chronic renal failure and to determine the cardiovascular predictors of mortality. The study comprised forty-five patients from the Renal Unit, University Hospital of the West Indies, Kingston, Jamaica, and was undertaken between October 1, 1998 and July 31, 2000. All echocardiography was done by a single operator. The parameters assessed were systolic dysfunction, diastolic dysfunction, ejection fraction, regional wall motion abnormalities and valvular disease. Left ventricular cavity size, septal and posterior wall thickness were measured and left ventricular mass calculated. Demographic data were obtained directly from each patient by interview. The patients were mainly of African/mixed-African origin. Their mean age was 43.2 +/- 16.0 years. The average body mass index was 23.7 +/- 6.9. Twenty-eight (60.9%) patients were male and seventeen (39.1%) female. Hypertension, chronic glomerulonephritis and diabetes mellitus were the leading causes of chronic renal failure. Blood pressure was controlled at a mean value of 145/90 mm Hg pre-dialysis and 140/90 mm Hg postdialysis. The mean duration of renal failure was 2.8 years. Echocardiographic M-mode and two dimensional apical, four chamber view measurements indicated that mean left ventricular internal diameter (LVID) diastole was 55.7 +/- 7.9 mm (normal 38-56 mm) and LVID systole was 38.9 +/- 9.8 mm (normal 24-45 mm); the mean thickness of the chamber walls was 10.3 +/- 2.8 mm and 10.6 +/- 2.4 mm for the interventricular septum (normal 6-11 mm) and left ventricular posterior wall (normal 6-11 mm) respectively. Diastolic dysfunction was seen in 15 (34%) patients and systolic dysfunction in 12 (23%) patients who had ejection fractions less than 50%. The mean left ventricular ejection fraction was 56.3% +/- 16% (normal 65-85%), mean stroke volume was 82.9 +/- 27.2 mls (normal 51-96 ml). After 21 months enrolment in the study, Kaplan Meier analysis revealed a two-year mortality of 28.3%. Cox regression analysis indicated that a history of smoking current or past, low haemoglobin level, high aorta flow velocities, severity of mitral regurgitation and a negative association with serum creatinine were independent predictors of mortality. The correction of anaemia and control of other factors that impact negatively on cardiac function in dialysis patients is vital to enhance survival.     

双脉冲波多普勒组织速度超声成像评价正常成年人心室不同水平面心肌机械运动时空特征

目的应用双脉冲波多普勒组织速度超声成像评价正常人心室短轴不同水平面心肌机械运动特征及表达时间差异,探讨其临床应用价值。方法应用双脉冲波多普勒组织速度超声成像同步采集100例健康成年人3个连续心动周期内二尖瓣、乳头肌及心尖3个水平左心室标准短轴切面,两两同步获取右心室游离壁、前间隔及左心室后壁心肌的双脉冲波多普勒组织速度超声图像。观察同一水平面左右心室心肌及同一室壁不同节段心肌机械运动特征。测量左心室短轴二尖瓣、乳头肌及心尖3个水平右心室游离壁、前间隔及左心室后壁共6个节段心肌在收缩期、快速充盈期及心房收缩期机械运动达峰时间(Ts、Te、Ta),分析同一水平面不同室壁心肌以及同一室壁不同节段心肌的机械同步顺序状态。结果双脉冲波多普勒组织速度图像显示:左心室短轴切面,同一水平的右心室游离壁与前间隔心肌运动方向一致,左心室后壁心肌与前两个室壁心肌运动方向相反。左心室短轴3个标准水平面,同一水平不同室壁心肌达峰时间:①前间隔心肌Ts最短;基底段和中间段,左心室后壁心肌较前间隔分别延迟约14和19ms,较右心室游离壁分别延迟约11和12ms(P均<0.001);心尖段,右心室游离壁心肌Ts最大,3个室壁心肌间差异无统计学意义(P>0.05)。②左心室后壁心肌Te最短,前间隔心肌Te最长,并且3个室壁心肌两两间的Te值差均有统计学意义(P均<0.001)。③左心室后壁心肌Ta最短,前间隔心肌Ta最长。前间隔和右心室游离壁心肌Ta值较左心室后壁延迟均约10ms(P均<0.001)。同一室壁心肌在左室不同水平面机械运动表达时间差异性:左心室后壁心肌从基底段至心尖段Ts值逐渐延长,中间段心肌较基底段延迟14ms,心尖段心肌较基底段延迟17ms(P<均0.001);心尖段心肌较中间段延迟仅3ms(P>0.05)。结论正常成年人心脏收缩及舒张期机械运动空间及时间上均具有不对称性;同一室壁不同节段心肌从心尖至基底收缩时间逐渐延长,舒张时间保持高度一致。双脉冲波多普勒组织速度超声成像能更客观的评价心脏收缩期及舒张早、晚期表达时间差异性。     

正常人心肌等容收缩期多普勒组织成像特点及其临床价值

目的探讨正常人心肌等容收缩期多普勒组织成像特点及其临床价值。方法应用多普勒组织成像（DTI）对30例正常人心肌进行检测。于标准胸骨旁左室长轴观、心尖左室长轴观、两腔观和四腔观,将取样容积分别置于左室前间隔、后壁、前壁、下壁、后间隔和侧壁的基底段和中段处内膜下心肌层,获取6个壁共16个取样点的组织多普勒图像,在每一个取样点的DTI图像上测量等容收缩期正向波、负向波的峰值速度（VIVC1,VIVC2）,持续时间（TIVCI,TIVC2）,速度时间积分（VTIIVC1,VTIIVC2）,并计算等容收缩期正、负向波峰值速度的差值DIVC（DIVC：VIVC1-VIVC2）。结果正常人左心室六个壁等容收缩期心肌各位点DTI频谱通常呈正向为主的正负双向型坡。除后壁外（包括纵向和横向）每个壁基底段、中段的VIVC1〉VIVC2,TIVC1〉TIVC2,VTIIVC1〉VTIIVC2（P〈0．05）,同一节段不同壁之间及同一壁不同节段间的VIVC1比较以及VIVC2比较差异多无统计学意义（P〉0．05）。结论正常心肌等容收缩期多普勒组织成像具有明显特点,应用其可对多种心脏疾病予以评价,因而具有重要临床意义。     

The Value of Conventional Echocardiographic and Tissue Doppler Imaging in the Diagnosis of Cardiac Amyloidosis

Transthoracic echocardiographic characteristics of 17 cases of cardiac amyloidosis （CA）, a rare disease in China, were analyzed in order to improve the understanding of the disease. Seventeen cases of biopsy-proven CA, admitted to Wuhan Union Hospital from June 1994 to September 2008 were retrospectively reviewed. Twenty normal volunteers served as control group. Left atrial and ventricular functions and mitral inflow velocity were measured by two-dimensional, and Doppler echocardiography, and tissue Doppler imaging （TDI）-derived peak systolic wall motion velocities （Sv）, peak early diastolic wall motion velocities （Ev）, and peak late diastolic wall motion （Av） were measured at the septum, lateral, inferior and anterior corners of mitral annulus from the apical 4-and 2 chamber views. Compared with the control group, the interventricular septal thickness （IVSd）, the left ventricular posterior wall （LVPWd）, right ventricular transverse diameter （RVTDd） near the end of diastole and the interauricular septum thickness （IASs）, left atrial anteroposterior diameter （LAADs）, right atrial transverse diameter （RATDs） near the end of systole were increased significantly （all P〈0.05） and left ventricular ejection fraction （LVEF） decreased （P〈0.05） in the CA group. Compared with the control group, Sv, Ev at each wall and Av at almost all walls were significantly decreased in the CA group. In the CA group, Myocardial echoes of interventricular septum and free wall of left ventricle were enhanced evidently and distributed unevenly. The echoes presented as ground glass-like images, with some spotty hyper echoes. Both atria were enlarged, and LVEF decreased, with diastolic function impaired, and mild-moderate hydropericardium found in the CA group. It was concluded that echocardiography was a relatively sensitive and highly specific non-invasive method for the diagnosis of CA.     

正常人利声显心肌声学造影显像效果观察

目的 静脉注射利声显心肌声学造影,比较不同超声切面心肌造影效果,探讨心肌灌注超声显像的最佳切面。方法 采用谐波一能量多普勒和间歇性显像方法,分别采集１５例正常人心尖四腔心、二腔心和胸骨旁四腔心切面的超声图像,观察心肌显像的效果。结果 在标准的心尖四腔、三腔和二腔心切面上在室后间隔、后壁和下壁显影良好,而侧壁、前间壁、前壁和心尖部出现假性充盈减弱或充盈缺损现象;胸骨旁四腔心切面基本可以弥补心尖四腔心     

速度向量成像技术评价正常人左心室节段心肌收缩功能的初步研究

目的应用速度向量成像技术(VVI)比较静息状态下左心室相同节段的正常心肌纵向和径向的运动特点,评价VVI技术对正常人左心室节段心肌收缩功能的临床应用价值。方法选取健康志愿者30例,采用西门子公司Sequoia 512超声诊断仪,在VVI模式下选取心尖四腔、心尖二腔、心尖左室长轴;二尖瓣水平、乳头肌水平及近心尖水平左室短轴切面,定量分析左室前间隔、前壁、侧壁、下壁、后壁及后间隔的径向运动,以及纵向的基底段、中间段及心尖段等3个分段中正常心肌节段的心肌运动速度(Vs)、应变(S)、应变率(SR)。结果正常人左心室各室壁基底段、中间段和心尖段速度依次递减:基底段>中间段>心尖段,差异有统计学意义(P<0.05);应变、应变率差异无统计学意义(P>0.05)。左心室各室壁二尖瓣水平、乳头肌水平、近心尖部水平径向速度、应变、应变率差异无统计学意义(P>0.05)。结论速度向量成像技术能够定量评价左心室节段收缩功能,为临床评价心脏运动及功能提供新方法。     

定量组织速度成像技术在心功能评价及左心衰竭诊断中的价值

目的 探讨定量组织速度成像（QTVI）技术对心功能的评价作用及其在诊断左心衰竭中的价值。方法 对30例左心衰竭患者及32例正常人行常规超声心动图检查,以简化双平面Simpson法计算出左室射血分数（LVEF）;使用QTVI技术,测量左室壁二尖瓣环6个位点的收缩期峰值速度（Vs）、收缩期最大位移（Ds）。比较心衰组与正常对照组、心衰组治疗前与治疗后的二尖瓣环6个位点平均Vs、平均Ds,并将平均Vs、平均Ds与LVEF做相关性分析,探讨QTVI技术对心功能的评价作用及其对左室收缩性心力衰竭的诊断价值。结果 二尖瓣环6个位点平均Vs,心衰组明显低于正常对照组[（2．8±0．6）cm／s vs（6．4±0．9）cm／s,P〈0．01],心衰组治疗后比治疗前显著升高[（3．5±1．1）cm／s vs （2．8±0．6）cm／s,P〈0．01];二尖瓣环6个位点平均Ds,心衰组显著低于正常对照组[（5．2±1．5）mm vs（11．6±1．5）mm,P〈0．01],心衰组治疗后比治疗前显著升高[（6．5±2．0）mm vs（5．2±1．5）mm,P〈0．01]。二尖瓣环6个位点平均Vs、平均Ds与LVEF呈显著正相关（r分别为0．87,0．89,均P〈0．01）。左室壁二尖瓣环6个位点平均Vs在诊断左心衰竭的受试者工作特征曲线下面积为0．95。以4．42cm／s为界值,二尖瓣环6个位点平均Vs诊断左心衰竭的敏感性为97．5％,特异性为90．2％,准确度为95．1％。左室壁二尖瓣环6个位点平均收缩期最大位移Ds在诊断左心衰竭的受试者工作特征曲线下面积为0．96。以8．49mm为界值,二尖瓣环6个位点平均Ds诊断左心衰竭的敏感性为97．5％,特异性为87．8％,准确度为95．1％。结论 QTVI技术测定的二尖瓣环6个位点的平均Vs、平均Ds可以评价左心室收缩功能,对左心衰竭有重要的诊断价值。     

超声心动图评价缬沙坦治疗原发性高血压的疗效

目的利用超声心动图评价缬沙坦治疗原发性高血压的疗效。方法将63例轻、中度高血压病患者入选为高血压组，服用缬沙坦80mg／d共12周。用药4周后对舒张压≥90mmHg者，以上剂量加倍，观察患者用药前后血压、超声心动图左心长轴切面舒张未期左室内径、室间隔、左室后壁厚度及室间隔背向散射积分（IBS）变化，并以30例健康志愿者为阴性对照。结果12周末缬沙坦能有效降压，可降低室间隔及左室后壁厚度（P〈0．01）及室间隔心肌背向散射积分，而左室内径治疗前后无统计学差异。结论缬沙坦治疗轻、中度高血压病疗效确切，可逆转患者心肌重塑。     

超声与冠状动脉造影、左室造影的对照研究

目的 :通过超声与冠状动脉 (简称冠脉 )造影、左室造影的对照研究 ,探讨超声检测冠心病的临床价值。　方法 :正常人 2 0例 ,拟行冠脉旁路移植术组 18例 ,观察 :①应用彩色多普勒冠脉血流显像技术 (CAFI)显示并测定冠脉血流脉冲多普勒频谱值。②经超声心动图显示和测定室壁运动和左室射血分数。拟行冠脉旁路移植术组需行冠脉造影和左室造影。　结果 :应用CAFI左前降支 (LAD)的显像率最高。拟行冠脉旁路移植术组 12例与正常人 2 0例应用CAFI测LAD血流脉冲多普勒频谱值间差异非常显著 (P <0 .0 0 1或P <0 .0 1) ,两组间左回旋支的钝圆支、冠脉后降支血流脉冲多普勒频谱值无显著差异 (均P >0 .0 5 )。超声与左室造影对照研究中室壁运动异常的检出无显著差异 (P >0 .0 5 )。 2例单支LAD狭窄 >90 %且无侧支循环建立者 ,超声均发现室壁瘤 ,这 2例超声与左室造影等所测左室射血分数最低。　结论 :本研究显示 ,CAFI能直接观察冠脉血流 ,超声观察室壁节段性运动异常可推测相关冠脉病变 ,左室重构对左心功能影响最为明显     

超声斑点追踪技术对免梗死心肌收缩运动的研究

目的探讨超声斑点追踪技术对诊断局部心肌室壁运动异常的临床应用价值。方法应用超声二维斑点追踪技术测量经外科手术结扎左冠状动脉前降支的10只新西兰雄性大白兔梗死节段室壁以及10只健康新西兰大白兔相对应心肌节段的二维应变值,记录其左室乳头肌短轴图像切面,测量各个节段的收缩期二维应变值,并应用SPSS13．0软件进行统计分析。结果通过超声二维斑点追踪技术,获得梗死组和对照组兔子相对应心肌节段收缩期的二维径向应变值。梗死组兔子的前间隔及左室前壁心肌节段收缩期径向应变值与正常对照组比较明显减低,有显著性差异（P〈0．05）。结论超声二维斑点追踪技术可准确评价节段性室壁运动异常,可为临床评价心肌梗死患者左心收缩功能提供一种准确率高且无创的新方法。     

Echocardiographic findings in patients with acute coronary syndrome and normal angiogram

Coronary angiograms performed at the time of an acute coronary syndrome typically present vessel occlusions, ruptured plaques or thrombotic lesions that require reperfusion therapy. However, occasionally, no coronary artery stenoses are detected. Myocardial ischemia frequently causes left ventricular wall motion abnormalities that can be seen easily by echocardiography. In our study we aimed to analyze echocardiographic findings in patients with acute coronary syndrome and normal angiogram. After standardized risk stratification, a total of 897 patients were classified as an acute coronary syndrome and underwent a coronary angiography immediately. In 76/897 patients angiography excluded coronary macroangiopathy. Routine echocardiographic assessment in patients with normal angiogram showed in 21.1% a reduced left ventricular systolic function and 32.9% presented with segmental wall motion abnormalities. In summary, by detection of segmental wall motion abnormalities in 1/3 of patients with suspected acute coronary syndrome and normal angiogram, obviously, an echocardiographic evaluation in this patient population is of clinical relevance. Recommendations for performing echocardiography in patients with suspected acute coronary syndromes independent of angiographic findings are strongly supported. Further analyses should implement echocardiographic techniques as contrast and tissue doppler imaging.     

实时三维超声心动图评价心肌梗死患者左室整体节段心功能及室壁运动的同步性

目的 应用实时三维超声心动图(RT-3DE)评价急性和陈旧性前壁心肌梗死患者左室整体节段舒缩功能及室壁运动同步性,并探讨左室整体及局部舒缩功能对左心室室壁运动同步性的影响.方法 急性前壁心肌梗死组20 例,陈旧性前壁心肌梗死组25 例,正常对照组22 例,均行常规二维及RT-3DE检查,通过Qlab 6.0定量分析软件...     

保留瓣下结构对二尖瓣置换术后室壁运动的影响

目的　探讨保留瓣下结构对二尖瓣置换术后室壁运动的影响。方法　对 73例二尖瓣狭窄为主的患者施行二尖瓣置换术 ,根据术中对自体瓣膜处理的方式分为全保组 ( 11例 )、全切组 ( 2 5例 )、保前组 ( 14例 )、保后组 ( 2 3例 ) ,另选 2 0名健康志愿者为正常组。采用超声心动图彩色室壁动态分析技术 (colorkinesisimages ,CK)对上述各病例组术后患者进行随访 ,以正常人作为对照 ,测量左室壁节段性位移幅度 ,比较各病例组间的差异。结果　各病例组间所有节段的室壁位移幅度的差异均无显著性 (P >0 .0 5 ) ;在心尖四腔切面 ,各病例组室间隔壁的基底段、中间段、尖段的位移幅度均较正常组差 (P <0 .0 5 ) ;在心尖二腔切面 ,各病例组下壁中间段、尖段的位移幅度均较正常组差 (P <0 .0 5 ) ;在瓣口水平切面 ,各病例组后壁、隔前壁和下壁的位移幅度均较正常组差 (P <0 .0 5 ) ;在乳头肌水平切面 ,各病例组的隔前壁和隔后壁的位移幅度均较正常组差 (P <0 .0 5 )。结论　本研究涉及的各种二尖瓣置换术后中期的室壁运动变化与正常人相比有明显差别 ,效果均不理想。探讨腱索合理牵拉方向和保留腱索的最佳长度可能是设计最佳手术方式的研究方向。     

斑点追踪超声心动图评价冠心病病人左心室收缩功能的研究

目的:应用超声二维斑点追踪技术（STI）评价冠心病病人左心室整体收缩期纵向应变（GLS）及18节段收缩期峰值纵向应变（LS）的变化。方法:选择经冠状动脉造影证实的冠状动脉狭窄≥50%的病例组35例和无冠状动脉狭窄的对照组25例,测量2组左心室GLS、左心室心尖两腔、四腔和三腔切面（AP2,AP4,AP3）的LS和18节段的LS。结果:2组GLS比较差异有统计学意义（P<0.01）,病例组基底段、前间隔和下壁中间段、前壁和后间隔的心尖段与对照组比较,其LS绝对值降低（P<0.05）;左心室的AP2、AP4、AP3的LS与对照组比较差异无统计学意义（P>0.05）。结论:STI超声心动图能够定量评价冠心病病人左心室心肌收缩运动的早期变化。     

缺血性心脏病左室收缩功能测定——左室数字减影、核素心室造影和超声心动图对比研究

本文利用左室数字减影(DSA)、核素心室造影(RNA)和超声心动图(UCG)对53名冠心病者和16名正常人进行左室收缩功能测定。结果示DSA与UCG改良Simpson氏和半球圆柱法相关性最好(r分别为0.84、0.70),与RNA法次之(r0.72),按有无节段性室壁运动障碍分组,则前壁运动障碍组DSA与UCG改良Sirepson和半球圆柱法相关性仍较好(r分别为0.84和0.82);下壁运动障碍组DSA与RNA和UCG相关性均较差。     

Spontaneous alterations in left ventricular regional wall motion after acute myocardial infarction.

For assessing the relationship between the left ventricular (LV) wall motion abnormalities and the status of residual flow to the infarcted region, the extent of coronary artery disease and one-year outcome, 60 patients with a first transmural, Q-wave myocardial infarction (MI) underwent serial echocardiographic examinations. The abnormal wall motion (AWM) score was calculated, and the cardiac events (death, reinfarction, severe ventricular arrhythmia or congestive heart failure) after discharge were recorded. The AWM score of the infarcted area was higher in patients with total occlusion than in those with subtotal occlusion (anterior MI: 14.6 +/- 2.4 vs 7.2 +/- 2.1; inferior MI: 9.7 +/- 2.1 vs 5.1 +/-1.2, all P less than 0.01). Regional wall motion of the noninfarcted area was preserved in patients with single vessel disease but decreased in those with multivessel disease. In patients who developed cardiac events in follow-up period a higher AWM (16.4 +/- 3.7) was found than in those who did not (8.9 +/- 3.1, P less than 0.05). A score of greater than 13 had a strong prediction of cardiac events after acute MI, with a sensitivity of 81%, specificity of 94% and positive predictive accuracy of 88%.

     

40例正常人心肌应变及应变率定量分析研究

目的应用超声应变及应变率技术研究正常人左心室心肌应变及应变率变化规律．方法应用定量组织多普勒技术对40例正常人左室各节段心肌进行应变和应变率定量分析．结果应变在前壁、前间隔、后间隔、侧壁、后壁表现为自基底段到心尖段逐渐递减,在下壁各节段间无显著性差异,后间隔应变最高;同一室壁不同节段显著性差异明显大于不同室壁的同等节段;应变率在不同室壁的同等节段显著性差异存在于中间段和心尖段．结论应变和应变率曲线中,无论在同一室壁不同节段还是在不同室壁同一节段上可能并无规律一致的分布模式。