Temperament characteristics of mentally retarded children

In a comparative study of temperament and intelligence in groups of mentally retarded and normal children, it was found that mentally retarded children who also had excess of psychopathology in them, showed greater signs of ‘difficult’ child temperament. Relationship between intelligence and emotionality variable of temperament was linear and positive in the mentally retarded children. This study generates the hypothesis that negative mood may be temperamental correlated with mental retardation.     

Comparison of three probiotics in the treatment of acute diarrhea in mentally retarded children

BACKGROUND: This article aims to compare the use of VIS-01 (Yovis) with two other probiotics (lactic acid bacteria), such as Lactogèrmine and Codex in the treatment of acute diarrhea in children with mental retardation. A recent paper highlights the superiority of the first drug, claiming new perspectives in probiotic therapy. METHODS: The authors perform a prospective study on 33 mentally retarded children (mean age 10.3 years), divided in three groups, each treated with a different probiotic (VIS-01, Lactogèrmine and Codex) at the beginning of an acute diarrhea. These children were admitted at the Pediatric Unit of the Oasi Maria SS. Institute in Troina. The dosage was suited to the technical record of the drug. During the clinical course the following items have been recorded: number of evacuations; time of alvine normalization; presence, quality, and length of fever; other associated features or side effects. RESULTS: The time of alvine normalization did not show statistically significant differences between the three groups. CONCLUSIONS: In conclusion, the use of Yovis does not modify in a statistically significant way with respect to the remaining drugs the clinical course of acute diarrhea in the mentally retarded children of the present study.     

The evaluation of reaction time on mentally retarded children

This study was designed to compare the parameters of reaction time on mentally retarded and healthy children and also to find out the effect of sport on reaction time. The study consisted of 20 non-retarded (group I), 20 non-sporting trainable mentally retarded (group II), and 20 sporting trainable mentally retarded (group III). The avarage age of subjects were determined as 15.35 +/- 0.21 years in group I, 15.00 +/- 0.22 years in group II, and 15.15 +/- 0.21 years in group III. The audiovisual reaction time of both non-retarded and retarded children were measured. It was found that reaction time is lower in trainable mentally retarded children (p < 0.05). It can be concluded that sport is a valid and effective means of training which affects the reaction time positively.     

Genetic analysis of a group of mentally retarded children

Genetic analysis of 169 mentally retarded (MR) children from Madras, revealed chromosomal abnormalities in 17%. Down syndrome was the major chromosomal anomaly (24/169=14.2%). These included three cases of trisomy-21 mosaics, and one case ofde novo Robertsonian translocation. MR children with chromosomal abnormalities were either mildly or moderately retarded. Syndromes with known etiology occurred in 3% of the MR cases. Microcephaly, neonatal anoxia, perinatal stress and pharmacological attempt for abortion were found to be important pathogenic factors associated with MR. Most of the microcephalies (11/ 169=6.5%) were severely retarded, whereas those associated with neonatal anoxia and perinatal stress were either mildly or moderately retarded. Birthorder effects were found only among Down syndrome patients. Segregation analysis of the three groups of proband families (viz. mild, moderate and severe MR) indicated that autosomal recessive mode of inheritance is compatible in moderate and severe MR proband families. The proportion of X-linked instances of MR is estimated to be about 22% of the cases.