人体瘦组织对骨密度的影响

目的探讨人体瘦组织对骨密度的影响。方法将160例进行DXA(Dual-energy x-ray absorptiometry双能X线骨密度吸收仪)骨密度和身体成分分析的患者作为研究对象,根据瘦组织指数将女性和男性患者平分为高瘦组织指数组和低瘦组织指数组,比较二组的股骨颈、全髋和腰椎骨密度。结果 54例高瘦组织指数组女性瘦组织指数为16.9942±1.2634 kg/m~2,54例低瘦组织指数组女性瘦组织指数为14.2981±0.7956 kg/m~2;26例高瘦组织指数组男性瘦组织指数为19.5200±1.0863 kg/m~2,26例低瘦组织指数组男性瘦组织指数为16.0654±1.4077 kg/m~2。男女高瘦组织指数组的股骨颈、全髋和腰椎骨密度均显著高于低瘦组织指数组(P0.05)。结论高瘦组织指数女性和男性患者均具有较高的股骨颈、全髋和腰椎骨密度。     

健康中年男性人体成分对骨密度的影响

目的探讨健康中年男性人体成分对骨密度影响,为男性骨质疏松早期防治提供理论依据。方法以上海市奉贤区128名年龄为40~60岁(平均49.10±6.40岁)的健康中年男性为研究对象,测定其身高、体重、腰围、臀围,并计算体重指数(BMI);利用问卷调查调查其文化程度、饮酒吸烟、豆制品及奶制品摄入情况、静坐时间、睡眠时间等一般情况;利用全自动生化分析仪测定血钙(Ca)、血磷(P)、肝肾功能(ALT、AST、BUN、Cr、UA)、血脂(TC、TG、HDL、LDL)、血糖(FPG、2h-PG),高压液相法测定糖化血红蛋白(HbA1c)等生化指标;采用双能X线骨密度仪测定腰椎、股骨颈、股骨干、股骨大粗隆和全身骨密度(BMD),并根据T值或Z值评分结果将所有研究对象分为骨量正常组和骨量低下组;采用人体成分分析仪测定体脂肪含量、蛋白质含量、无机盐含量、骨骼肌含量和各部位肌肉含量。结果 128名年龄为40~60岁健康中年男性中,骨质疏松患者3人,骨量减少患者44人。骨量正常组体重、BMI、腰围、臀围、睡眠时间、蛋白质含量、无机质含量、骨骼肌含量、各部位肌肉含量皆高于骨量低下组,血清尿素及吸烟人数比率低于骨量低下组,且差异具有统计学意义;两组年龄、身高、饮酒情况、文化程度、工作性质、豆制品摄入情况及奶制品摄入情况、Ca、P、Cr、UA、ALT、AST、TC、TG、HDL、LDL、FPG、2h-PG、HbA1c、体脂肪及体脂百分比皆无统计学差异。结论适当延长每天睡眠时间有利于预防骨质疏松的发生;体重、BMI、腰围、臀围是骨质疏松的保护因素,但需通过加强体育锻炼及合理饮食,增加骨骼肌、无机质及蛋白质等非脂肪含量来增加骨密度预防骨质疏松。     

身体成分对绝经后女性骨密度和骨骼肌量的影响

目的 基于双能X线骨密度仪测量的身体成分分析,探讨影响绝经后女性骨密度和骨骼肌量的共同因素,为绝经后骨质疏松和肌少症的协同防治提供思路。方法 纳入2015年1月至2020年10月在中山大学附属第一医院进行身体成分分析的171例绝经后女性,根据全身骨密度和相对骨骼肌肉指数(relative skeletal muscle index,RSMI)分为正常组(T值≥-1且RSMI＞5.45 kg/m2)、肌少组(T值≥-1且RSMI≤5.45 kg/m2)、骨量异常组(T值＜-1且RSMI＞5.45 kg/m2)和肌少/骨量异常组(T值＜-1且RSMI≤5.45 kg/m2)。采用单因素方差分析比较4组一般资料和身体成分差异,Pearson相关分析研究身体成分与骨密度和RSMI的相关性,多元线性回归分析探索影响骨密度和RSMI的共同因素。结果 4组在体脂率(percent body fat,PBF)、脂肪量(fat mass,FM)、脂肪指数(fat mass index,FMI)、瘦组织(lean mass,LM)、瘦组织指数(lean mass index,LMI)、骨矿盐含量(bone mineral content,BMC)、Android/Gynoid区域脂肪比率和休止代谢率(resting metabolic rate,RMR)的整体比较中差异均有统计学意义(P＜0.05)。调整混杂因素后,PBF、FM、FMI与骨密度和RSMI呈不同程度负相关,LM、LMI、BMC、RMR与骨密度和RSMI呈正相关。多元线性回归显示高PBF、低LM和低BMC是骨密度和RSMI的共同危险因素。结论 绝经后女性骨密度与骨骼肌量变化密切相关,针对影响二者的共同危险因素采取干预措施可能有利于绝经后骨质疏松和肌少症的协同防治。     

肌肉组织和脂肪组织对绝经后女性骨密度及骨强度的影响及作用机制

目的 探讨肌肉组织和脂肪组织对绝经后女性骨密度及骨强度的影响及作用机制。方法 检索近10年来研究绝经后女性肌肉和（或）脂肪对骨密度和（或）骨强度的影响的专业文献以及研究肌肉、脂肪和骨骼相互影响的具体机制的实验报告, 综合分析肌肉组织和脂肪组织对绝经后女性骨密度及骨强度的影响及作用机制。结果 多数研究表明肌肉组织含量及肌力可能是骨密度和骨强度的重要决定因素,骨髓脂肪会对骨骼产生不利影响,而髓外脂肪对骨密度及骨强度的影响则尚未达成一致认识;无论是肌肉组织还是脂肪组织,均可通过力学作用和化学调节两方面影响骨代谢,从而影响骨密度和骨强度,但其具体机制尚未完全阐明。结论 ①肌肉组织是骨密度及骨强度的重要影响因素,其在力学因素和化学调节等多方面对骨骼 起到正向保护作用,但具体机制尚需进一步研究。②骨髓脂肪增多与骨质疏松症负性相关已被认可,而髓外脂肪组织对骨密度及骨强度影响较为复杂,有待进一步研究探讨。③对于绝经后女性而言,通过合理锻炼和饮食等方式维持肌肉含量和肌力以及一定范围的体脂,对防治骨质疏松有重耍的积极意义。     

宁波男性骨密度和骨质疏松影响因素的研究

目的评价宁波市男性健康人群的骨量和骨质疏松(OP)的发病情况。方法794名健康男性采用Sunlight的超声骨密度测定胫骨的超声速度值(SOS)。并按年龄、民族、生活习惯进行分组,以10岁为1个年龄组,生活习惯包括吸烟、酗酒、户外活动(大于1h/d)和喝咖啡者。结果宁波市男性骨SOS峰值年龄在30～39岁,60岁以后OP患病率23.4%,过量吸烟、饮酒和喝咖啡者骨SOS值低于同年龄组,户外活动者(如爬山、慢跑)平均日照不少于1h/d,骨质情况优于同年龄组其他人,骨质疏松患病率也较低,本市的不同民族男性各年龄段的骨质差异无显著性。结论宁波市健康男性骨质状况良好,但生活不良嗜好是本地区影响骨密度的重要因子,应当提倡良好的生活习惯。     

吸烟对男性骨密度的影响

为探讨吸烟对男性骨密度的影响，我们用单光子骨矿分析仪测量了１４５例３０～５０岁吸烟男性的骨密度和１１２例同年龄不吸烟男性的骨密度，报告如下。资料和方法１．病例选择：本组２５７例３０～５０岁男性患者。均无糖尿病、甲状旁腺机能亢进、肿瘤、肾病等病史。其中有吸烟嗜好１４５例。吸烟标准为个人史中有吸烟嗜好，每天吸烟１包以上。另设对照组１１２例，为无吸烟嗜好的同年龄男性患者。２．方法：骨密度测量用中国原子能科学研究所和北京广播技术研究所联合研制的ＢＭＤ—４型骨矿分析仪，测量部位为前臂，右力者测左臂，左力者…     

补钙对骨密度的影响

随着我国人口老龄化趋势的日益明显 ,骨质疏松已成为中老年人的一种常见病和多发病。而在骨质疏松的传统治疗上 ,不但治疗成本高 ,并且治疗效果不是十分理想。尤其在一些基层医疗单位 ,普通病人在经济上难以承受。目前在评价骨质疏松的诊断和治疗上 ,一个指标是骨矿密度 ,另一个指标是骨强度。而据美国最新的资料表明 ,由于目前没有测定整体骨强度的检测仪器 ,通常用骨矿密度 (BMD)指标来代替 ,它大约反映 70 %的骨强度[1] 。因此 ,我们通过观察补充钙剂对骨质疏松患者骨密度的影响 ,旨在寻找一种通过增加人体骨密度而达到防治骨质疏松的…     

脂蛋白a对2型糖尿病男性骨密度的影响

目的探讨正常范围内的脂蛋白a对男性2型糖尿病患者骨密度的影响,为防治2型糖尿病 患者的骨质疏松提供一定依据。方法选取66例血清脂蛋白a正常（0 -300 mg/L)的男性2型糖尿 病患者（糖尿病病程5年以内）,测定血脂系列、骨代谢等指标;采用双能X线吸收骨密度仪（DXA)测 定腰椎（L1-L4 )、股骨（Neck、Troch、Inter、Total、Wards )骨密度。按照脂蛋白a水平,将研究对象分为 年龄、BMI相匹配的低脂蛋白a组（0-130 mg/L)和高脂蛋白a组（131 ~ 300 mg/L),分析骨密度及骨 代谢的差异。结果1、高脂蛋白a组的股骨（Troch)及腰椎（L1、L2、L3、L4、Total Lumbar)骨密度明显 高于低脂蛋白 a 组（Troch:P = 0. 020 ; L1 ：P = 0. 022 ; L2 ： P = 0. 035 ; L3 ：P = 0. 030 ; L4 ：P = 0. 007 ; Total Lumbar :P=0. 016 ),高脂蛋白a组Neck、Inter及Ward’ s骨密度高于低脂蛋白a组,但差异不具有统 计学意义（P=0. 068、P = 0. 249、P = 0. 107 )。2、高脂蛋白a组的骨转换指标（I型胶原、骨钙素）较低 脂蛋白a组降低,但差异不具有统计学意义（P = 0.682、P = 0. 322)。3、股骨颈（Neck)、腰椎（L3、L4、 Total Lumbar〉骨密度与血浆脂蛋白 a 水平正相关(Neck ： r = 0. 270,P = 0. 028 ;L3 :r = 0. 250,P = 0. 043 ; L4 = r = 0.302,P = 0. 015 ;Total Lumbar: r = 0. 262,P = 0. 033 )。结论在 2 型糖尿病男性中,脂蛋白 a 可能通过调节骨转换而影响全身的骨代谢及骨密度。     

运动对骨密度的影响

运动疗法是骨质疏松治疗的一项基本方法。通过运动治疗可以提高患者的运动能力，减少跌倒和骨折发生的危险。此外，运动对于骨密度还有直接的作用。人们从运动对于骨密度的影响机制、作用特点等方面作了许多广泛深入的研究，为临床运用提供了良好的指导。     

韶关地区中年男性骨密度调查分析

目的 调查韶关地区部分中年男性人群骨密度。方法 应用双能X线骨密度仪对韶关地区236名中年男性进行骨密度检测、分析。结果 37．71％的中年男性出现不同程度的骨量减少，3．81％患有骨质疏松症。结论 中年男性骨质疏松的防治问题不容忽视。     

Contribution of lean tissue mass to the urban-rural difference in bone mineral density

While the urban-rural difference in bone mineral density (BMD) has been shown in some, but not all, Western populations, such a difference and the reason for the difference is largely unknown, particularly in developing countries. This cross-sectional, epidemiologic study was designed to examine the hypothesis that differences in measures of body composition such as lean mass (LM) and fat mass (FM) contribute to the urban-rural difference in BMD. Lean mass, fat mass, lumbar spine and femoral neck BMD were measured by DXA (GE Lunar Corp, Wis.) in 411 urban (Bangkok city) and 436 rural (Khon Kaen province) Thai subjects, aged 20–84 years. Rural men and women had significantly higher LM and lower FM than their urban counterparts. In multiple linear regression analysis, age, LM, menopausal status (in women) and residence were independent determinants of BMD. After adjusting for age, menopause and LM, rural subjects were found to have significantly higher femoral neck BMD, but not lumbar spine BMD, than urban subjects. Furthermore, to alleviate the potential effect of multicolinearity of LM and FM, each rural subject was matched with each urban subject for FM and age, which resulted in 46 pairs of men and 91 pairs of women. In this matched-pair analysis, the femoral necks in rural men and women were, respectively, 7.3±2.1% (mean±SE; P <0.01) and 6.3±2.8% ( P <0.02) higher than in urban men and women. The urban-rural difference in LM accounted for approximately 23 and 5% of the urban-rural difference in femoral neck BMD in men and women, respectively. These data are thus consistent with the hypothesis that the urban-rural difference in BMD at a weight-bearing site is in part associated with the urban-rural difference in lean mass.     

The influence of early steroid withdrawal on body composition and bone mineral density in renal transplantation patients

Corticosteroid treatment may have an important effect on body composition and bone mineral density (BMD) in renal transplantation (RTx) patients. We investigated the effect of early steroid withdrawal on body composition and BMD of RTx patients in a prospective design. Post-transplant immunosuppression consisted of tacrolimus, mycophenolate mofetil, and prednisolone. Three months after RTx, 27 patients participating in a multi-center trial were randomized either to continue steroids (at a dose of 10 mg/day, n=17; steroid+) or be withdrawn from steroids within 2 weeks (n=10; steroid-). Body composition and BMD (lumbar spine (L2-L4) and femoral neck) were measured by dual-energy X-ray absorptiometry (DEXA) just before and 3 months after randomization. With regard to body composition, fat mass tended to increase in the steroid+ group (1.1+/-2.3 kg; P=0.084), but did not change in the steroid- group. Increase in body fat percentage tended to be higher (P=0.08) in the steroid+ group (0.6+/-2.7%) than in the steroid- group (-0.7+/-2.1%). The change in lean body mass was not significantly different between the two groups. BMD of the lumbar spine and femoral neck decreased significantly in the steroid+ group (-1.4+/-3.2% and -2.3+/-2.9%, respectively, P<0.05) while no changes were observed in the steroid- group. The change in BMD of the lumbar spine was significantly different between the steroid+ and the steroid- group, whereas the change in BMD of the femoral neck was not significantly different. Thus, the increase in fat mass tended to be higher in the group continuing on steroids, though not significant, due to large inter-individual variation. In general, the effect of early steroid withdrawal on body composition after RTx appears to be modest. In addition, early steroid withdrawal seems to have beneficial effects on BMD in RTx patients, especially in the lumbar region.     

仫佬族绝经前与绝经后女性体成分和骨密度的相关性研究

目的研究仫佬族绝经前与绝经后女性体成分和骨密度的相关关系,探讨体成分的变化对骨密度的影响。方法随机选取广西仫佬族成年女性200名,追溯其三代均为仫佬族,应用TANITA-MC180人体成分分析仪测定其肌肉量、脂肪量等体成分指标,采用SONOT3000超声骨密度仪测定其右侧跟骨的骨硬度指数。结果 (1)绝经前女性的体重、去脂体重、肌肉量、皮下脂肪量、躯干脂肪量、四肢肌肉量、推定骨量、骨硬度指数和T值等均显著高于绝经后女性(P0.01);而绝经前女性的内脏脂肪面积、腰臀比显著低于绝经后女性(P0.01)。(2)绝经前女性和绝经后女性的骨质疏松检出率分别为6%和45%,差异具有统计学意义(P0.01)。(3)相关分析发现肌肉量、四肢肌肉量和躯干肌肉量与骨密度之间存在显著的正相关关系(P0.01或P0.05),而当控制年龄和绝经状态后体成分和骨密度之间没有相关性;根据年龄分组后发现,≥50岁组的肌肉量各指标与骨密度存在较显著的关联(P0.05),而50岁组的体成分与骨密度不存在关联性(P0.05)。(4)多重逐步回归分析发现只有绝经状态、躯干肌肉量和内脏脂肪量与骨密度相关,而躯干肌肉量对骨密度影响最大。结论仫佬族绝经后女性的骨质疏松症发生率显著高于绝经前女性;控制年龄和绝经因素后,只有躯干肌肉量与骨密度较显著相关,结果可为骨质疏松症的预防和诊断提供理论依据。     

探讨体重指数对绝经后老年妇女不同部位骨密度的影响

目的分析不同体重指数患者的腰椎和股骨近端、股骨颈、Ward’s三角区的骨密度及T值评分,探讨体重指数对绝经老年妇女不同部位骨密度的影响。方法以我院225例年龄均为60以上的绝经老年妇女为研究对象,计算体重指数将患者分为体瘦组、正常组和肥胖组,检测患者腰椎和股骨近端、股骨颈、Ward’s三角区的骨密度,分析各部位骨密度变化与体重指数的关系。结果体瘦组的患者各部位骨密度明显低于正常和肥胖组的患者,体瘦组与正常组或肥胖组比较,腰椎(L1～L4)、股骨颈、股骨近端、Ward’s三角区的骨密度均有显著的差异(P<0.01);正常组与肥胖组比较,仅L3和L4的骨密度有显著的差异(P<0.05),其余部位的骨密度无显著的差异(P>0.05)。结论体重和体重指数是影响骨密度的一个重要因素,体重和体重指数与绝经老年妇女不同部位的骨密度存在一定的相关性,低体重指数的绝经老年妇女,骨丢失而引起的骨量减少明显,易发生骨质疏松。     

体重体成分与骨密度的关系

为了研究体成分与骨密度（ＢＭＤ）之间的关系，因体重与ＢＭＤ显著相关，体成分各个组成相加等于体重，而体成分与ＢＭＤ的关系仍不清楚。方法随机选取２０６名１６～５２岁健康的男女性汉族人，用双能Ｘ射线吸收法（ＤＸＡ）测量ＢＭＤ与体成分，进行ＢＭＤ与体重，体成分的多元线性回归分析。结果体重，瘦组织（ＬＴＭ）与男女性的ＢＭＤ显著正相关，脂肪组织（ＦＴＭ）仅对女性全身，腰椎ＢＭＤ起显著性作用。结论影响男女性ＢＭＤ的体成分中，ＬＴＭ是主要因素，ＦＴＭ仅对女性ＢＭＤ有影响。本文较全面地研究了体成分与ＢＭＤ的关系。     

老年女性腰椎骨密度与年龄及椎旁体质成分相关性分析

目的探讨不同腰椎椎体骨密度(bone mineral density,BMD)与年龄及同层面椎旁腰大肌、竖脊肌、腹部脂肪、血管钙化情况的关系。方法收集体检中心行腰椎检查的老年女性90名,采用定量CT(quantitative CT,QCT)及后处理软件测量L2-L4椎体骨密度及三椎体同层面椎旁体质成分。统计学处理应用配对t检验、Pearson相关分析和多元逐步回归分析等。结果①3组椎体BMD均与年龄均呈负相关(P0.05),L2BMD、L3BMD均与双侧腰大肌、竖脊肌密度成正相关(r=0.233~0.301,P均0.05)。而L4BMD显示与双侧竖脊肌密度及腹部脂肪面积有良好的相关性,均呈正相关。②多元逐步回归分析显示除年龄外,肌肉是影响BMD的重要因素。年龄是唯一全部进入3组腰椎BMD回归方程,并呈负相关,是影响腰椎BMD的重要因素。结论老年女性的腰椎骨密度与椎旁腰大肌、竖脊肌密度,腹部脂肪面积及年龄密切相关,除年龄外椎旁肌肉密度对骨密度影响最大。QCT扫描更加直观、精确显示椎骨与椎旁体质成分情况,可作为测量诊断骨质疏松、体质成分的新手段。     

A meta-analysis of the effects of cigarette smoking on bone mineral density

To determine the magnitude and mediators of the association between cigarette smoking and bone mass in the epidemiologic literature we reviewed articles, published abstracts and conference proceedings, identified through MEDLINE, psychological abstracts, conference proceedings, and article bibliographies. We studied cross-sectional and prospective human studies that provided a quantitative measure of bone mass (X-ray, absorptiometry, or computed tomography) as a function of cigarette smoking exposure. Effects were expressed as pooled standardized mean differences for categorical comparisons (e.g. bone mass in current versus nonsmokers), and as pooled correlation coefficients for continuous comparisons (e.g., correlation of bone mass and pack-years of smoking). Effects were derived for combined bone sites (all bone sites pooled within each study) and four specific sites (hip, lumbar spine, forearm, and os calcis), and were examined overall and as a function of subject and methodologic characteristics (gender, age, body weight, menopausal status, health status). Data were pooled across 86 studies, enrolling 40, 753 subjects. Smokers had significantly reduced bone mass compared with nonsmokers (never and former smokers) at all bone sites, averaging a one-tenth standard deviation (SD) deficit for combined sites. Deficits were especially pronounced at the hip, where the bone mass of current smokers was one-third of a SD less than that of never smokers. Overall, effects were greatest in men and in the elderly, and were dosedependent. In prospective studies, smokers had greater rates of bone loss over time compared with nonsmokers. Bone mass differences remained significant after controlling for age and body weight differences between the two groups. Absolute effect sizes at most bone sites were greatest for current smokers compared with never smokers, intermediate for current smokers compared with former smokers, and lowest for former smokers compared with never smokers, suggesting that smoking cessation may have a positive influence on bone mass. Based on these data, it is estimated that smoking increases the lifetime risk of developing a vertebral fracture by 13% in women and 32% in men. At the hip, smoking is estimated to increase lifetime fracture risk by 31% in women and 40% in men. It appears that smoking has an independent, dose-dependent effect on bone loss, which increases fracture risk, and may be partially reversed by smoking cessation. Given the public health implications of smoking on bone health, it is important that this information be incorporated into smoking prevention and cessation efforts     

Analysis of factors affecting increase in bone mineral density at lumbar spine by bisphosphonate treatment in postmenopausal osteoporosis

Bisphosphonate is an effective drug to reduce fracture risk in osteoporotic patients; however, factors affecting the efficacy of bisphosphonate treatment are not fully known, especially in Japanese patients. In the present study, we examined the relationships between an increase in lumbar spine bone mineral density (BMD) by bisphosphonates and several pretreatment parameters, including biochemical, bone/mineral, and body composition indices, in 85 postmenopausal osteoporotic patients treated with alendronate or risedronate. BMD increase was measured by dual-energy X-ray absorptiometry at the lumbar spine before and 2 years after treatment. BMD increase at the lumbar spine was observed as independent of age, height, weight, body mass index, and fat mass, although lean body mass seemed slightly related. On the other hand, fasting plasma glucose (FPG) levels were significantly and positively related to BMD increase at the lumbar spine. In multiple regression analysis, FPG levels were not significantly related to BMD increase at the lumbar spine when lean body mass was considered. As for bone/mineral parameters, BMD increase at the lumbar spine was not significantly related to serum levels of calcium, parathyroid hormone (PTH), and alkaline phosphatase or urinary levels of deoxypiridinoline and calcium excretion. As for BMD parameters, Z-scores of BMD at any site and bone geometry parameters obtained by forearm peripheral quantitative computed tomography were not significantly related to BMD increase at the lumbar spine. BMD increases at the lumbar spine were similar between groups with or without vertebral fractures. In conclusion, BMD increase at the lumbar spine by bisphosphonate treatment was not related to any pretreatment parameters, including body size, body composition, and bone/mineral metabolism in postmenopausal Japanese women with primary osteoporosis, although FPG correlated partly to BMD through lean body mass.     

广州地区1 403例成年女性骨密度测定分析

目的了解本地区成年女性人群腰椎、股骨近端各部位骨密度(Bone mineral density BMD)随年龄、绝经年限、体重、身高的变化规律、各部位骨密度的偏相关分析和多元线性回归分析及骨质疏松患病率情况,为骨质疏松的诊断及预防提供科学依据.方法采用美国NORLAND公司的XR-46系列双能X线骨密度仪测量1 403例成年女性人群腰椎(L2-L4前后位及L3侧位)、非优势(左)股骨近端各部位(股骨颈、大粗隆及Ward's三角)BMD值,按10岁一个年龄组分7组对数据进行统计分析.结果广州地区成年女性腰椎骨峰含量出现在30～39岁组,而股骨近端骨峰含量出现在20～29岁组,腰椎及股骨近端各部位BMD值均随年龄增长而下降,腰椎和Ward's三角部位在50～59岁和60～69岁两年龄组骨量呈快速丢失现象.各部位骨密度的偏相关分析显示各部位的骨密度均呈相关性(P＜0.01).多元线性回归分析显示年龄和体重对绝经前女性股骨颈的骨密度有影响(P＜0.01),而绝经后女性腰3侧位骨密度除了年龄和体重的影响外,身高和绝经年限均对其有影响(P＜0.01).成年女性在达到峰值骨量后随着年龄的增加,各部位骨质疏松的患病率都呈上升趋势.结论女性机体BMD随年龄而变化,年龄、体重、绝经年限及身高等对机体BMD均有一定的影响,保持合适的体重和体型,有利于BMD的增加与维持.对不同年龄段的成年女性人群,预防骨质疏松的发生应以测量不同部位的BMD作为评价手段.