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1.
James H. Rimmer Amy E. Rauworth Edward C. Wang Terry L. Nicola Bernadette Hill 《Archives of physical medicine and rehabilitation》2009,90(3):407-412
Rimmer JH, Rauworth AE, Wang EC, Nicola TL, Hill B. A preliminary study to examine the effects of aerobic and therapeutic (nonaerobic) exercise on cardiorespiratory fitness and coronary risk reduction in stroke survivors.
Objectives
To compare the effects of 3 different exercise training regimens on cardiorespiratory fitness and coronary risk factor reduction in subjects with unilateral stroke.Design
A cluster assignment by residential location repeated-measures design.Setting
University-based medical center.Participants
Fifty-five subjects with unilateral ischemic stroke were assigned to the following groups: intensity (n=18), duration (n=19), and therapeutic exercise (n=18).Intervention
A 14-week intervention with subjects randomized to 1 of 3 interventions: (1) moderate intensity, shorter duration (MISD) exercise (gradually increasing exercise intensity while keeping exercise duration constant at 30 min), (2) low-intensity, longer duration (LILD) exercise (gradually increasing duration to 60 min while keeping exercise intensity constant), or (3) conventional therapeutic exercise (TE) consisting mainly of strength, balance, and range of motion activities. All groups exercised 3 days per week.Main Outcome Measures
Peak oxygen consumption (Vo2peak), submaximal oxygen consumption (V?o2), lipid panel, and resting blood pressure.Results
The MISD group attained more favorable effects on systolic (P<.04) and diastolic blood pressure (P<.002) and total cholesterol (TC) (P<.036) compared with LILD and TE groups. Both MISD (P<.029) and LILD (P<.045) showed significant reductions in triglycerides compared with TE (P<.029). There was no significant change in Vo2peak and submaximal V?o2 in any of the groups.Conclusions
Overall, both MISD and LILD conditions achieved greater clinical and significant gains in coronary risk reduction compared with TE. 相似文献2.
Objective
To systematically review the psychometric evidence on the 2-minute walk test (2MWT).Data Sources
Electronic searches of databases including MEDLINE, CINAHL, Academic Search Premier, SPORTDiscus, PsycINFO, EMBASE, the Cochrane Library, and DARE were done until February 2014 using a combination of subject headings and free texts.Study Selection
Studies were included if psychometric properties of the 2MWT were (1) evaluated; (2) written as full reports; and (3) published in English language peer-reviewed journals.Data Extraction
A modified consensus-based standard for the selection of health measurement instruments checklist was used to rate the methodological quality of the included studies. A quality assessment for statistical outcomes was used to assess the measurement properties of the 2MWT.Data Synthesis
Best-evidence synthesis was collated from 25 studies of 14 patient groups. Only 1 study was found that examined the 2MWT in the pediatric population. The testing procedures of the 2MWT varied across the included studies. Reliability, validity (construct and criterion), and responsiveness of the 2MWT also varied across different patient groups. Moderate to strong evidence was found for reliability, convergent validity, discriminative validity, and responsiveness of the 2MWT in frail elderly patients. Moderate to strong evidence for reliability, convergent validity, and responsiveness was found in adults with lower limb amputations. Moderate to strong evidence for validity (convergent and discriminative) was found in adults who received rehabilitation after hip fractures or cardiac surgery. Limited evidence for the psychometric properties of the 2MWT was found in other population groups because of methodological flaws.Conclusions
There is inadequate breadth and depth of psychometric evidence of the 2MWT for clinical and research purposes—specifically, minimal clinically important changes and responsiveness. More good-quality studies are needed, especially in the pediatric population. Consensus on standardized testing procedures of the 2MWT is also required. 相似文献3.
Chia-Hsin Chen Shih-Feng Lin Wan-Hui Yu Jau-Hong Lin Hao-Ling Chen Ching-Lin Hsieh 《Archives of physical medicine and rehabilitation》2014
Objective
To compare the test-retest reliabilities of the scores of the Balance Computerized Adaptive Test (CAT) and the Biodex Balance System in patients with stroke.Design
A repeated-measures design (at a 1-wk interval) was used to examine the test-retest reliabilities of the scores of the Balance CAT and the Biodex Balance System.Setting
One rehabilitation unit in a local hospital.Participants
Patients (N=50) with stroke for more than 6 months and undergoing outpatient rehabilitation completed the Balance CAT and the eyes open (EO)/closed (EC) tests, but only 17 patients finished the Limit of Stability (LOS) test because they were unable to reach all the targets.Interventions
Not applicable.Main Outcome Measures
The Balance CAT and 2 computerized tests of the Biodex Balance System, namely the EO/EC test and the LOS, were used to evaluate balance function.Results
The test-retest reliabilities of the scores of the Balance CAT (Pearson r=.92, minimal detectable change [MDC] percent=12.8%) was excellent. Those of the EO/EC and LOS tests were poor to good (Pearson r=.56–.85, MDC%=50.8%–126.9%).Conclusions
The test-retest reliabilities of the scores of the Balance CAT were sufficient for assessing balance function in patients with stroke. Moreover, the test-retest reliabilities of the scores of the Balance CAT, one of the functional balance measures, were superior to those of the Biodex Balance System, 1 type of computerized posturography instrument. Therefore, the Balance CAT may be a more reliable measure for clinicians and researchers to use in assessing the balance function of patients with stroke for more than 6 months. 相似文献4.
Lynnette G. Kay Anita C. Bundy ScD Lindy M. Clemson PhD 《Archives of physical medicine and rehabilitation》2009,90(9):1514-1522
Kay LG, Bundy AC, Clemson LM. Predicting fitness to drive in people with cognitive impairments by using DriveSafe and DriveAware.
Objectives
To examine the psychometric properties of DriveSafe and DriveAware and their predictive validity.Design
Prospective study compared screening tests with criterion standard.Setting
Two driving rehabilitation centers affiliated with a university and a geriatric rehabilitation facility.Participants
Consecutive sample of drivers with functional impairments (n=115) and subgroup of drivers with cognitive impairments (n=96) referred for a driving assessment.Interventions
Not applicable.Main Outcome Measure
Driving performance was measured by a standardized assessment in real traffic.Results
Rasch analysis provided evidence for construct validity and internal reliability of both tests. Tests trichotomized drivers into unsafe, safe, and further testing categories. The optimal lower cutoff identified unsafe drivers with a specificity of 97% (95% confidence interval [CI], 83-100) in the test sample and 96% (95% CI, 80-100) in the validation sample. The optimal upper cutoff identified safe drivers with a sensitivity of 93% (95% CI, 77-99) and 95% (95% CI, 76-100), respectively.Conclusions
By using DriveSafe and DriveAware, drivers with cognitive impairments referred for a driving assessment can be categorized as unsafe, safe, or requiring further testing, with only 50% needing an on-road assessment. Before clinical practice is changed, these findings should be replicated. 相似文献5.
Ya-Chen Lee Wan-Hui Yu Yu-Fen Lin I-Ping Hsueh Hung-Chia Wu Ching-Lin Hsieh 《Archives of physical medicine and rehabilitation》2014
Objective
To examine the intrarater reliability, interrater reliability, and responsiveness of the Activities of Daily Living Computerized Adaptive Testing system (ADL CAT) in patients with stroke.Design
One repeated-measures design (at an interval of 7d) was used to examine the intrarater reliability and interrater reliability of the ADL CAT. For the responsiveness study, participants were assessed with the ADL CAT at admission to the rehabilitation ward and at discharge from the hospital.Setting
Eight rehabilitation units.Participants
Three different (nonoverlapping) groups of patients (N=157) were recruited. Fifty-five and 42 outpatients with chronic stroke participated in the intrarater and interrater reliability studies, respectively; 60 inpatients who had recently had a stroke participated in the responsiveness study.Interventions
Not applicable.Main Outcome Measure
ADL CAT.Results
The intraclass correlation coefficient values were .94 and .80 for the ADL CAT in the intrarater reliability and interrater reliability studies, respectively. The classical test theory–based minimal detectable change values were 6.5 and 9.5 for the ADL CAT in the intrarater reliability and interrater reliability studies, respectively. The Kazis' effect size and standardized response mean of the ADL CAT were moderate (.62–.73).Conclusions
The ADL CAT has good intrarater reliability and interrater reliability in outpatients with chronic stroke, and sufficient responsiveness in inpatients with stroke undergoing inpatient rehabilitation. Further investigations on the responsiveness of the ADL CAT in outpatients are needed to obtain more evidence on the utility of the ADL CAT. 相似文献6.
Rafael Mesquita Daisy J.A. Janssen Emiel F.M. Wouters Jos M.G.A. Schols Fabio Pitta Martijn A. Spruit 《Archives of physical medicine and rehabilitation》2013
Objective
To investigate the within-day test-retest reliability of the Timed Up & Go (TUG) test in patients with advanced chronic obstructive pulmonary disease (COPD), chronic heart failure (CHF), and chronic renal failure (CRF).Design
Cross-sectional.Setting
Patients' home environment.Participants
Subjects (N=235, 64% men; median age, 70y [interquartile range, 61–77y]; median body mass index, 25.6kg/m2 [interquartile range, 22.8–29.4kg/m2]) with advanced COPD (n=95), CHF (n=68), or CRF (n=72).Interventions
Not applicable.Main Outcome Measure
Time to complete the TUG test. Three trials were performed on the same day and by the same assessors. The intraclass correlation coefficient (ICC), kappa coefficient, standard error of measurement, and absolute and relative minimal detectable change (MDC) values were calculated.Results
Good agreement was observed, in general, for both the total sample and subgroups (COPD, CHF, CRF), with ICC values ranging from .85 to .98, and kappa coefficients from .49 to 1.00. However, statistical improvement occurred in the total sample from the first to the second trial with large limits of agreement (mean difference, −.97s; 95% confidence interval, 3.00 to −4.94s; P<.01). The third trial added little or no information to the first 2 trials. For the total sample, a standard error of measurement value of approximately 1.6 seconds, an absolute value of MDC at the 95% confidence level (MDC95%) of approximately 4.5 seconds, and a relative value of MDC at the 95% confidence level (MDC95%%) of approximately 35% were found between the first 2 trials, with similar values found for the subgroups.Conclusions
The TUG test is reliable in patients with advanced COPD, CHF, or CRF after 2 trials. Values of standard error of measurement and MDC may be used in daily clinical practice with these populations to define what is expected and what represents true change in repeated measures. 相似文献7.
No neuropsychologic studies have been reported that assess cognitive functioning in survivors of locked-in syndrome (LIS) due to purely pontine lesions and then document the process of recovery by serial testing over a lengthy period. A previously well man in his early thirties was admitted to the hospital with progressive stroke symptoms and signs. Investigations showed occlusion of the basilar artery and acute infarction of the pons, including basis and tegmentum. Despite thrombolysis, he had persisting clinical features of the LIS. He had minimal change during the first month but then slowly improved. Recovery continued gradually, and he was discharged home 7 months after stroke; at this time he was ambulating with a cane, was mildly dysarthric, was able to swallow foods of modified consistency, and was independent in all self-care activities. Neuropsychologic testing, done 6 months after stroke, showed noteable cognitive impairments. These included mild difficulties with attention and concentration, significant reduction in speed of processing, moderate impairment of perceptual organization skills, mild inefficiencies in new learning of verbal information, and a moderate reduction in executive skills. Pathologic laughing and crying were also noted. There was progressive improvement in most areas of physical and cognitive functioning until at least 2 years after stroke. Neuropsychologic testing in this patient suggests that the LIS may be associated with impairments of higher-level cognitive functioning. 相似文献
8.
Yiqin Mong Tilda W. Teo Shamay S. Ng 《Archives of physical medicine and rehabilitation》2010,91(3):407-307
Mong Y, Teo TW, Ng SS. 5-repetition sit-to-stand test in subjects with chronic stroke: reliability and validity.
Objectives
To examine the (1) intrarater, interrater, and test-retest reliability of the 5-repetition sit-to-stand test (5-repetition STS test) scores, (2) correlation of 5-repetition STS test scores with lower-limb muscle strength and balance performance, and (3) cut-off scores among the 3 groups of subjects: the young, the healthy elderly, and subjects with stroke.Design
Cross-sectional study.Setting
University-based rehabilitation center.Participants
A convenience sample of 36 subjects: 12 subjects with chronic stroke, 12 healthy elderly subjects, and 12 young subjects.Interventions
Not applicable.Main Outcome Measures
5-Repetition STS test time scores; hand-held dynamometer measurements of hip flexors, and knee flexors and extensors; ankle dorsiflexors and plantarflexors muscle strength; Berg Balance Scale (BBS); and limits of stability (LOS) test using dynamic posturography.Results
Excellent intrarater reliability of intraclass correlation coefficient (ICC) (range, .970-.976), interrater reliability (ICC=.999), and test-retest reliability (ICC range, .989-.999) were found. Five-repetition STS test scores were also found to be significantly associated with the muscle strength of affected and unaffected knee flexors (ρ=-.753 to -.830; P<.00556) of the subjects with stroke. No significant associations were found between 5-repetition STS test and BBS and LOS tests in subjects with stroke. Cut-off scores of 12 seconds were found to be discriminatory between healthy elderly and subjects with stroke at a sensitivity of 83% and specificity of 75%.Conclusions
The 5-repetition STS test is a reliable measurement tool that correlates with knee flexors muscle strength but not balance ability in subjects with stroke. 相似文献9.
10.
Submaximal exercise in persons with stroke: test-retest reliability and concurrent validity with maximal oxygen consumption 总被引:2,自引:0,他引:2
OBJECTIVE: To establish the test-retest reliability and concurrent validity with maximum oxygen consumption (VO2max) for 3 submaximal exercise tests in persons with chronic stroke: (1) submaximal treadmill test, (2) submaximal cycle ergometer test, and (3) 6-minute walk test (6MWT). DESIGN: Prospective study using a convenience sample. SETTING: Free-standing tertiary rehabilitation center. PARTICIPANTS: A volunteer sample of 12 community-dwelling individuals who had a stroke with moderate motor deficits. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Heart rate, blood pressure, and oxygen consumption (VO2) were assessed during the exercise tests. RESULTS: Test-retest reliability was good to excellent for the exercise tests (maximal and submaximal tests). VO2 for all submaximal measures related to VO2max (r range, .66-.80). Neither the 6MWT distance, self-selected gait speed, nor hemodynamic measures related to VO2max. CONCLUSION: The VO2 measures of the submaximal exercise tests had excellent reliability and good concurrent validity with VO2max. Submaximal exercise tests may be a method by which to monitor the effects of interventions after a screening test (eg, symptom-limited graded exercise test, dobutamine stress echocardiograph). 相似文献
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13.
Jeroen C. Vis MD Hanneke Thoonsen MD Marielle G. Duffels MD Rianne A. de Bruin-Bon Sylvia A. Huisman MD Arie P. van Dijk MD PhD Elke S. Hoendermis MD PhD Rolf M. Berger MD PhD Berto J. Bouma MD PhD Barbara J. Mulder MD PhD 《Archives of physical medicine and rehabilitation》2009,90(8):1423-1427
Vis JC, Thoonsen H, Duffels MG, de Bruin-Bon RA, Huisman SA, van Dijk AP, Hoendermis ES, Berger RM, Bouma BJ, Mulder BJ. Six-minute walk test in patients with Down syndrome: validity and reproducibility.
Objectives
To examine the validity of the six-minute walk test (6MWT) as a tool to evaluate functional exercise performance in patients with Down syndrome (DS).Design
Comparison of the six-minute walk distance (6MWD) in 2 distinct groups of DS patients: with and without severe cardiac disease. To test reproducibility, a group of patients with DS performed the 6MWT twice.Setting
Tertiary referral centers for patients with congenital heart defects and outpatient clinics for people with intellectual disabilities.Participants
Adult patients with DS with (n=29) and without (n=52) severe cardiac disease categorized by cardiac echocardiography.Interventions
Not applicable.Main Outcome Measure
Distance walked on the 6MWT.Results
The mean 6MWD in the group with severe cardiac disease was 289±104m and in the group without severe cardiac disease 280±104m (P=.70). Older age, female sex, and severe level of intellectual disability were all found to be independently and significantly correlated with a lower 6MWD (r=.67, P<.001). The paired 6MWD was not significantly different (310±88m vs 317±85m; P=.40) in patients who performed the 6MWT twice. The coefficient of variation was 11%.Conclusions
The 6MWD between the 2 groups was not significantly different. However, the walking distance inversely correlated with the level of intellectual disability. Therefore, the 6MWT is not a valid test to examine cardiac restriction in adult patients with DS. 相似文献14.
15.
Ekaterina Tankisheva An Bogaerts Steven Boonen Hilde Feys Sabine Verschueren 《Archives of physical medicine and rehabilitation》2014
Objectives
To investigate the effects of a 6-week whole body vibration (WBV) training program in patients with chronic stroke.Design
Randomized controlled pilot trial with 6 weeks' follow-up.Setting
University hospital.Participants
Adults with chronic stroke (N=15) were randomly assigned to an intervention (n=7) or a control group (n=8).Interventions
Supervised, intensive WBV training. The vibration group performed a variety of static and dynamic squat exercises on a vibration platform with vibration amplitudes of 1.7 and 2.5mm and frequencies of 35 and 40Hz. The vibration lasted 30 to 60 seconds, with 5 to 17 repetitions per exercise 3 times weekly for 6 weeks. Participants in the control group continued their usual activities and were not involved in any additional training program.Main Outcome Measures
The primary outcome variable was the isometric and isokinetic muscle strength of the quadriceps (isokinetic dynamometer). Additionally, hamstrings muscle strength, static and dynamic postural control (dynamic posturography), and muscle spasticity (Ashworth Scale) were assessed.Results
Compliance with the vibration intervention was excellent, and the participants completed all 18 training sessions. Vibration frequencies of both 35 and 40Hz were well tolerated by the patients, and no adverse effects resulting from the vibration were noted. Overall, the effect of intensive WBV intervention resulted in significant between-group differences in favor of the vibration group only in isometric knee extension strength (knee angle, 60°) (P=.022) after 6 weeks of intervention and in isokinetic knee extension strength (velocity, 240°/s) after a 6-week follow-up period (P=.005), both for the paretic leg. Postural control improved after 6 weeks of vibration in the intervention group when the patients had normal vision and a sway-referenced support surface (P<.05). Muscle spasticity was not affected by vibration (P>.05).Conclusions
These preliminary results suggest that intensive WBV might potentially be a safe and feasible way to increase some aspect of lower limb muscle strength and postural control in adults with chronic stroke. Further studies should focus on evaluating how the training protocol should be administered to achieve the best possible outcome, as well as comparing this training protocol to other interventions. 相似文献16.
Hsin-Yu Chiang Wen-Shian Lu Wan-Hui Yu I-Ping Hsueh Ching-Lin Hsieh 《Archives of physical medicine and rehabilitation》2018,99(8):1499-1506
Objective
To examine the interrater and intrarater reliability of the Balance Computerized Adaptive Test (Balance CAT) in patients with chronic stroke having a wide range of balance functions.Design
Repeated assessments design (1wk apart).Setting
Seven teaching hospitals.Participants
A pooled sample (N=102) including 2 independent groups of outpatients (n=50 for the interrater reliability study; n=52 for the intrarater reliability study) with chronic stroke.Interventions
Not applicable.Main Outcome Measures
Balance CAT.Results
For the interrater reliability study, the values of intraclass correlation coefficient, minimal detectable change (MDC), and percentage of MDC (MDC%) for the Balance CAT were .84, 1.90, and 31.0%, respectively. For the intrarater reliability study, the values of intraclass correlation coefficient, MDC, and MDC% ranged from .89 to .91, from 1.14 to 1.26, and from 17.1% to 18.6%, respectively.Conclusions
The Balance CAT showed sufficient intrarater reliability in patients with chronic stroke having balance functions ranging from sitting with support to independent walking. Although the Balance CAT may have good interrater reliability, we found substantial random measurement error between different raters. Accordingly, if the Balance CAT is used as an outcome measure in clinical or research settings, same raters are suggested over different time points to ensure reliable assessments. 相似文献17.
Amy J. Litterini Vickie K. Fieler James T. Cavanaugh Jeannette Q. Lee 《Archives of physical medicine and rehabilitation》2013
Objective
To compare the effects of resistance and cardiovascular exercise on functional mobility in individuals with advanced cancer.Design
Prospective, 2-group pretest-posttest pilot study with randomization to either resistance or cardiovascular exercise mode.Setting
Comprehensive community cancer center and a hospital-based fitness facility.Participants
Volunteer sample of individuals (N=66; 30 men; 36 women; mean age, 62y) with advanced cancer recruited through the cancer center, palliative care service, rehabilitation department, and a local hospice.Interventions
Ten weeks of individualized resistance or cardiovascular exercise, prescribed and monitored by oncology-trained exercise personnel.Main Outcome Measures
Functional mobility was assessed using the Short Physical Performance Battery (SPPB); self-reported pain and fatigue were assessed secondarily using visual analog scales. Data were analyzed using a split plot 2×2 analysis of variance (α=.05).Results
Fifty-two patients (78.8%) completed the study: 23 (67.7%) of 34 patients in the resistance arm and 29 (90.6%) of 32 patients in the cardiovascular arm. No participant withdrew because of study adverse events. Ten-week outcomes (n=52) included a significant increase in SPPB total score (P<.001), increase in gait speed (P=.001), and reduction in fatigue (P=.05). Although cardiovascular exercise participants had a modestly greater improvement in SPPB total score than resistance training participants (F1,49=4.21, P=.045), the difference was not confirmed in a subsequent intention-to-treat analysis (N=66).Conclusions
Individuals with advanced cancer appear to benefit from exercise for improving functional mobility. Neither resistance nor cardiovascular exercise appeared to have a strong differential effect on outcome. 相似文献18.
《Archives of physical medicine and rehabilitation》2023,104(6):965-981
ObjectivesTo review the evidence regarding the most common practices adopted with cardiopulmonary exercise testing (CPET) in individuals with spinal cord injury (SCI), with the following specific aims to (1) determine the most common averaging strategies of peak oxygen uptake (V̇o2peak), (2) review the endpoint criteria adopted to determine a valid V̇o2peak, and (3) investigate the effect of averaging strategies on V̇o2peak values in a convenience sample of individuals with SCI (between the fourth cervical and sixth thoracic spinal segments).Data SourcesSearches for this scoping review were conducted in MEDLINE (PubMed), EMBASE, and Web Science.Study SelectionStudies were included if (1) were original research on humans published in English, (2) recruited adults with traumatic and non-traumatic SCI, and (3) V̇o2peak reported and measured directly during CPET to volitional exhaustion. Full-text review identified studies published before April 2021 for inclusion.Data ExtractionExtracted data included authors name, journal name, publication year, participant characteristics, and comprehensive information relevant to CPET.Data SynthesisWe extracted data from a total of 197 studies involving 4860 participants. We found that more than 50% of studies adopted a 30-s averaging strategy. A wide range of endpoint criteria were used to confirm the attainment of maximal effort. In the convenience sample of individuals with SCI (n=30), the mean V̇o2peak decreased as epoch (ie, time) lengths increased. Reported V̇o2peak values differed significantly (P<.001) between averaging strategies, with epoch length explaining 56% of the variability.ConclusionsThe adoption of accepted and standardized methods for processing and analyzing CPET data are needed to ensure high-quality, reproducible research, and inform population-specific normative values for individuals with SCI. 相似文献
19.
Leonard A. Kaminsky Mary T. Imboden Ross Arena Jonathan Myers 《Mayo Clinic proceedings. Mayo Clinic》2017,92(2):228-233
The importance of cardiorespiratory fitness (CRF) is well established. This report provides newly developed standards for CRF reference values derived from cardiopulmonary exercise testing (CPX) using cycle ergometry in the United States. Ten laboratories in the United States experienced in CPX administration with established quality control procedures contributed to the “Fitness Registry and the Importance of Exercise: A National Database” (FRIEND) Registry from April 2014 through May 2016. Data from 4494 maximal (respiratory exchange ratio, ≥1.1) cycle ergometer tests from men and women (20-79 years) from 27 states, without cardiovascular disease, were used to develop these references values. Percentiles of maximum oxygen consumption (VO2max) for men and women were determined for each decade from age 20 years through age 79 years. Comparisons of VO2max were made to reference data established with CPX data from treadmill data in the FRIEND Registry and previously published reports. As expected, there were significant differences between sex and age groups for VO2max (P<.01). For cycle tests within the FRIEND Registry, the 50th percentile VO2max of men and women aged 20 to 29 years declined from 41.9 and 31.0 mLO2/kg/min to 19.5 and 14.8 mLO2/kg/min for ages 70 to 79 years, respectively. The rate of decline in this cohort was approximately 10% per decade. The FRIEND Registry reference data will be useful in providing more accurate interpretations for the US population of CPX-measured VO2max from exercise tests using cycle ergometry compared with previous approaches based on estimations of standard differences from treadmill testing reference values. 相似文献