高血压患者血清铜锌铁镁含量测定与分析

采用原子吸收分光光度法,检测了３０例高血压患者血清铜、锌、铁、镁４种元素。结果表明,高血压病组血清锌显著低于正常组（Ｐ＜０．０５）,血清铁、镁显著高于正常组（Ｐ＜０．０５）,铜锌比值显著高于正常组（Ｐ＜０．０５）,血清铜略低于正常组,无显著差异     

急性脑血管病全血微量元素含量的研究

用火焰原子吸收法及原子荧光法测定９５例急性脑血管病患者全血中锌、铜、硒、铬、镁的含量。结果表明全血中锌、硒、铬、镁含量均降低，锌／铜比值降低，铜增高，与正常对照组比较，有统计学意义（Ｐ＜０．０１）；并且缺血性脑血管病与出血性脑血管病相比较，锌、铜、铬、硒有显著性差异（Ｐ＜０．０１）。     

急性脑血管病患者头发微量元素测定分析

对１２１例急性脑出血和１４０例急性脑梗塞患者头发进行微量元素铬、硒、铜、锌、镁、锰、铁检测其含量。结果显示急性脑出血与急性脑梗塞组发铬、硒、铜、锌、镁均降低，铬、硒含量脑梗塞组比脑出血组降低更为明显，而脑梗塞组发铁明显低于正常，锰明显高于正常，而脑出血组锰、铁均正常。     

小儿肾小球疾病血清微量元素测定与分析

采用原子吸收分光光度法,测定了７８ 例肾小球疾病患儿血清铜、锌、铁、镁４ 种元素。结果显示,单纯性肾病组、肾炎性肾病组、紫癜性肾病组及肾炎组血清锌均显著低于正常组（ Ｐ＜ ００５）,血清铁、镁与正常组比较无显著差异。单纯性肾病组,肾炎性肾病组血清铜显著低于正常组（ Ｐ＜ ００５）。提示血清铜、锌、铁、镁含量的变化与疾病发生和疾病状态有关。     

广州铁路地区分娩半年内不同喂养方式产妇头发微量元素检测85例

对广州铁路地区分娩半年内８５例产妇的头发，测定锌、铜、铁、钙、镁５种必需微量元素，以纯母乳喂养、混合喂养、人工喂养分组，将测定值各组间对比，各组值又分别与广州地区正常妇女相应正常值对比，得出结果：广州铁路地区分娩半年内不同喂养方式产妇头发锌、铜、铁、钙、镁正常值对比，临床无差异（Ｐ＞０．５）；与广州地区正常妇女头发锌、铜、铁、钙、镁正常值对比，临床无差异（Ｐ＞０．２～０．５）。     

微量元素铜锌钙镁铁检测及临床营养学意义分析

目的：通过对微量元素铜锌钙镁铁的检测并分析临床营养学意义，旨在为改善微量元素平衡降低疾病发生提供理论依据。方法：选择2013年1月-2014年1月在我院接受治疗的因微量元素铜锌钙镁铁导致营养不良的患者260例作为研究组，在选择同期接受检查的正常患者260例作为对照组，应用原子吸收光谱仪对各微量元素进行检测，分析铜锌钙镁铁等微量元素对临床营养学的意义。结果：研究组患者铜锌钙镁铁含量分别为8．44Ug／L、85．10Ug／L、301．92Ug／L、8．03Ug／L、26．11Ug／L，显著低于对照组，且P〈O．05差异有统计学意义。结论：缺乏微量元素铜锌钙镁铁导致患者出现贫血、生长发育迟缓、智力障碍等，因此对于微量元素的早期检测时有效预防疾病提高患者生活质量的重要依据。     

老年胃脘痛患者10种元素测定分析与中西辨证施治

老年胃脘痛（胃溃疡慢性萎缩性胃炎）患者检测血液中１０种元素钙，镁，铜，锌，铁，铬，镍，锶，锰，铅结果与健康老人结果对照，患病组锌，铁降低，铬增高，有显著差异（Ｐ〈０．０５）。老年胃溃疡慢性萎缩性胃炎祖国医学辨证属胃脘痛脾胃气虚。脾胃气虚者锌，铁降低，铬增高，治疗是补充所需元素。     

575例儿童指血5种元素检测结果分析

目的:了解儿保门诊0～7岁儿童指血5种元素含量,并对其结果进行分析,探讨其综合防治措施。方法:采用BH 5 100型五通道原子吸收光谱仪对儿保门诊575例0～7岁儿童指血铜、锌、钙、镁、铁含量进行检测,并进行统计分析。结果:不同年龄组儿童锌、铁含量随年龄增长而升高(3～7岁组除外),钙含量0～岁组正常,且随年龄增长而降低。镁含量在正常范围,仅1例儿童铜缺乏。男童、女童间铜、锌、钙、镁含量差异无统计学意义,铁含量差异有统计学意义。结论:不同年龄组儿童5种元素含量不同,婴儿期锌、铁缺乏明显,应定期为儿童做微量元素检测,并在医生指导下合理补充微量元素,尤其在婴幼儿期应注意补充锌、铁,合理补钙。     

老年胃脘痛患者10种元素测定分析与中医辨证施治

老年胃脘痛（胃溃疡慢性萎缩性胃炎）患者检测血液中１０种元素钙、镁、铜、锌、铁、铬、镍、锶、锰、铅结果与健康老人结果对照，患病组锌、铁降低，铬增高，有显著差异（Ｐ＜０．０５）。老年胃溃疡慢性萎缩性胃炎祖国医学辨证属胃脘痛脾胃气虚。脾胃气虚者锌、铁降低，铬增高，治疗是补充所需元素。     

肾病患儿血清微量元素的测定及意义

目的观察肾病患儿血清铜、锌、铁、镁含量。方法采用原子吸收分光光度法测定肾病患儿血清铜、锌、铁、镁与正常对照组进行比较。结果单纯性肾病组、肾炎性肾病组、紫癜性肾病组及肾炎组血清锌均显著低于正常对照组P〈0．05，血清铁、镁与正常对照组比较无显著差异P〉0．05。单纯性肾病组，肾炎性肾病组血清铜显著低于正常对照组P〈0．05。结论血清铜、锌、铁、镁含量的变化与疾病发生和疾病状态有关。     

哺乳期农村乳母乳汁无机元素含量的变化

目的了解哺乳期人乳无机元素含量的变化及其与乳母膳食的关联。方法采用横断面调查方法,收集55名陕西省澄城县农村健康乳母清晨乳样,利用原子吸收分光光度法测定乳汁钙、镁、铁、锰、锌和铜的浓度。采用24小时回顾法进行连续3天膳食调查,计算膳食营养素的摄入量。结果农村乳母乳汁中镁、锌、铜浓度随哺乳期延长明显降低,铁浓度随哺乳期延长而上升。乳母膳食钙摄入量约为钙膳食参考摄入量(DRI)1/3,膳食无机元素的摄入量与人乳相应元素之间无明显相关性。多因素分析表明,乳汁中钙与镁、铁与铜、锰与锌均呈正相关,钙分别与乳脂、铁、锌呈负相关。结论随哺乳期时间延长,成熟乳中镁、锌、铜浓度降低而铁浓度增加,乳母膳食钙的摄入严重不足,乳汁各元素与膳食相应元素之间无关联。     

1800名婴幼儿头发中铜锌铁钙镁含量探讨

目的 :通过对武汉市某区 180 0名 3岁以下婴幼儿发样分析 ,探讨该区婴幼儿发中铜、锌、铁、钙、镁含量的正常水平和婴幼儿部分微量元素营养状况。方法 :采集婴幼儿发样进行预处理后用火焰原子光谱法测定其铜、锌、铁、钙、镁含量 ,并对测定结果进行卫生统计学处理。结果 :发铜在性别间有显著性差异 (P <0 .0 5 ) ,年龄间差异无显著性 (P >0 0 5 ) ;发锌、钙、镁、铁性别间差异不显著 (P >0 .0 5 ) ,0～ 3月组与其它组别差异显著(P <0 0 5 ) ,0～ 3月婴儿发中铜、锌、铁、钙、镁含量均处于一个较高水平。锌、铜随着年龄的增长至 3～ 12月其含量均呈下降趋势 ,随着年龄进一步增长至 12～ 2 4月 ,其含量略呈回升趋势。铁、钙、镁的含量随年龄的增加呈下降趋势 ,但均处于正常水平 ,且钙与镁呈伴随趋势。结论 :婴幼儿应加强微量元素的营养补充。     

肾病综合征、肾小球肾炎患儿血清铜、锌、铁、镁与血清蛋白质的测定与分析

采用原子吸收分光光度法,测定50 例肾病综合征患儿、28 例肾小球肾炎患儿血清铜、锌、铁、镁元素,并探讨这些元素与上述疾病的相互关系。结果显示,肾病综合征组和肾小球肾炎组血清锌均极显著低于正常组( P< 0-01) ,血清铁、镁与正常组比较无显著性差异,血清锌浓度与血清白蛋白、球蛋白含量呈显著正相关。肾病综合征组血清铜极显著低于正常组(P< 0-01) ,肾小球肾炎组血清铜与正常组比较无显著差异,血清铜浓度与血清白蛋白、球蛋白含量呈显著正相关。提示这些变化与疾病的发生和疾病状态有关     

Determination of Trace Metals Abnormalities in Patients with Vivax Malaria

Background

In the present study, blood serum level of metals were determined in malarial patients and compared with those in the normal subjects without complication using Atomic Absorption Spectrometer.

Methods

For the determination of these metals twelve intravenous blood samples each from referred malarial patients and a group of normal subjects were collected and immediately centrifuged to obtain the supernatant liquid, serum of both the groups for analysis.

Results

The blood serum levels of copper in malarial patients determined to be 2.6917 ppm, which is higher as compared to that found 2.045 in normal subjects. Whereas the blood serum levels of iron, magnesium, and zinc found 2.0708 ppm, 12.2467 ppm and 4.9017 ppm respectively in malarial patients, who are lower than those, are determined in the blood serum of normal subjects. Blood serum levels of iron, magnesium, and zinc in normal subjects found 3.950 ppm, 19.4892 ppm, and 5.242 ppm respectively.

Conclusion

In this study the metal content of copper, iron, magnesium and zinc in vary in malarial patients as compared those in the normal subjects. It may suggest that the decreased levels of iron, magnesium, and zinc can be maintained by giving as supplement of these metals in therapy.     

Effect of glucocorticoids and calcium intake on bone density and bone, liver and plasma minerals in guinea pigs.

The purpose of this study was to see what effect glucocorticoids would have on bone density and mineral distribution in guinea pigs. Adult female guinea pigs were given prednisolone, a synthetic analogue of cortisol, for up to 24 weeks. Bone density and bone, liver and plasma levels of zinc, copper, iron, manganese, chromium, magnesium and calcium were studied in these animals. In one study, the effect of menopause was simulated by using ovariectomy. In another study, dietary calcium was varied to investigate its effect with glucocorticoids. Animals treated with 1 mg prednisolone/kg body weight showed increased femur density compared with controls, but no changes in tissue mineral concentrations. Animals fed 100 mg prednisolone/kg body weight experienced decreased femur density. Differences in effects were not observed between ovariectomized and intact animals. Bone loss was greatest in animals fed the cereal-based closed-formula diet and least in animals fed the low-calcium diet. Changes in mineral content of femurs observed in animals which lost bone mass were increased iron concentration and decreased magnesium concentration. Total liver stores of zinc and magnesium increased. Liver copper increased in concentration per gram as well as in total content. Liver concentration of manganese decreased. Plasma changes in animals fed the high level of drug were decreased iron and calcium, and increased copper. Hemoglobin and hematocrit increased with increasing drug levels. It is suggested that glucocorticoids have marked effects on mineral metabolism which may be related to the bone loss and that these effects may be modified by dietary changes.     

早孕妇女微量元素含量监测105例对照分析及饮食指导

目的:探讨深圳市早孕妇女微量元素含量,指导孕妇合理补充。方法:应用元素分析仪,监测105例早孕妇女血清微量元素铜、锌、铁、钙、镁、铅、镉等含量作为研究组,选择同期正常妇女105例作为对照组,对照分析两组微量元素缺乏的种类及发生率。结果:研究组铜、锌平均含量高于对照组,钙、镁、铁则低于对照组;研究组和对照组缺锌发生率均较高,达21.90%和23.81%;研究组缺铁发生率明显高于对照组、缺铜的发生率低于对照组。结论:深圳市早孕妇女以缺铁、缺锌、缺铜为主,缺钙者不多,通过饮食补充微量元素是最安全的有效途径。     

Influence of mineral intake and use of oral contraceptives before pregnancy on the mineral content of human colostrum and of more mature milk

The effects of mineral intake and long-term oral contraceptive use before pregnancy on the mineral content of milk of healthy lactating women were evaluated in a study of 52 volunteers ages 18-31. Subjects reporting previous oral contraceptive use had significantly lower levels of copper in serum, perhaps reflecting reduced copper stores resulting from prolonged estrogen exposure, but concomitant changes in copper levels in their milk were not noted. Serum calcium and magnesium levels were not significantly affected by prior pill use. Pill use had no significant effect on concentrations of calcium, magnesium, zinc, copper, or iron in colostrum at day 3 or more mature milk at day 14 of lactation, while mean manganese levels were significantly lower at both times for previous oral contraceptive users (but still exceeded manganese levels recommended for infants). Mineral and vitamin supplementation significantly improved the levels of zinc and iron intake, but did not appreciably alter the mineral content of milk. Higher levels of zinc were found in colostrum compared to day 14 milk, while manganese concentrations increased significantly during the 1st 2 weeks of lactation. Calcium, magnesium, iron and copper levels did not change significantly as lactation progressed. Levels of calcium, magnesium, zinc, copper, and manganese in colostrum were significantly positively correlated with the mineral concentration on day 14. No significant diurnal or daily variation was observed in the levels of calcium, magnesium, or zinc content in milk during 2 24-hour periods.     

临产孕妇血清与新生儿脐血血清微量元素的研究

目的:探讨临产孕妇血清与新生儿脐血血清中微量元素钙、镁、锌、铁、铜的含量及其临床意义。方法:采用日立7 600型自动生化分析仪及罗氏自动生化分析仪测定210例孕妇血清及新生儿脐血血清的钙、镁、锌、铁、铜含量,并进行对照研究。结果:新生儿脐血血清中铁、钙、锌含量高于孕妇血清(P0.05);临产孕妇血清铜含量高于新生儿脐血血清(P0.05);新生儿脐血血清与临产孕妇血清中镁的含量比较无统计学差异(P0.05);维吾尔族孕妇血清及新生儿脐血血清与汉族孕妇血清及新生儿脐血血清钙、镁、铜、锌、铁含量无统计学差异(P0.05)。结论:①血清微量元素铁、钙、锌、镁的减少,铜的升高可能导致妊娠期疾病的发生。②无论孕妇机体在正常状态下还是在病理状态下,均需首先保证胎儿对锌、铜、铁、钙、镁的需要。③孕期应定期监测微量元素,合理补充微量元素钙、锌、铁,从而减少妊娠期疾病的患病率,保证孕妇身体健康和胎儿的正常生长发育。