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1.
Tumorigenesisproceedsthroughanaccumulationofspecificgeneticalterations Recentstudieshavefocusednotonlyonthederegulationofcellproductionbutalsoontheinhabitationofcellloss Thisstudyassessedtherelationshipbetweenapoptoticstatusandbiologicalbehaviorduring…  相似文献   

2.
Chroniccutaneousulcersrepresentamajorhealth careproblemwithconsiderablesocioeconomicimpact 1,2Traditionally,localtreatmentofchroniccutaneousulcersconsistsofconstantlocalwoundcare ,surgery ,skingrafting,debridementandvascularreconstruction Chroniculcersmayi…  相似文献   

3.
Molecular genetic analysis of a Chinese patient with Fabry disease   总被引:4,自引:0,他引:4  
FabrydiseaseisanX linkedlysosomalstoragediseasecharacterizedbyaccumulationofglycosphingolipidsinendothelialcells,fibroblasts,smoothmusclecells,andepithelialcellsofthekidney Thereisacharacteristicskinlesion,angiokeratomacorporisdiffusumuniversalis,whichc…  相似文献   

4.
Itisdifficulttoblockthetransmissionofschistosomiasisbychemotherapy ,thereforemanyresearchershavebeeninterestedinthestudyofvaccineofschistosomiasis Thestudyofvaccineofschistosomiasiswasmostlyfocusedonanti infectionimmunity ,butthemosthopefulcandidatemole…  相似文献   

5.
Ithasbeenreportedthattheclassicalmodelofthedominanceofthelefthemisphereofhumanbrainisincorrectbecauseitisinaccuratetosaythatwhichhemisphereisdominant Thehemispheresareasymmetricalintheirfunction Inthisstudywetriedtofindouttheactivatedareasandtoconfirm…  相似文献   

6.
CelladhesionmoleculesmaymediatethechemotacticmigrationbetweencellsorcellsandinterstitiumRecentstudies1,2havefoundthatdialysiswithcellulosemembranescouldleadtochangesintheexpressionofleukocyteadhesionmolecules,suchasCD11bandLselectin,ongranulocytesandmon…  相似文献   

7.
Woundhealingistheprocessbywhichcellproliferationisstringentlycontrolled ProgressionthroughtheG1phaseandinitiationofthecellcycleinmammaliancellsdependsonthebalanceofinteractionbetweencellcyclepositiveregulatorssuchascyclinD1,cyclinE ,cyclin dependentkina…  相似文献   

8.
Lymphangiomyomatosis   总被引:1,自引:0,他引:1  
Lymphangiomyomatosis (LAM )isaprogressivediseaseaffectingwomenofchildbearingage Itismicroscopicallycharacterizedbyabnormalsmoothmuscleproliferationthatcausesgradualobstructionofsmallairways ,lymphaticsandvasculature Theproliferationeventuallyresultsinach…  相似文献   

9.
Chronicperiodontitisisaverycommonoraldisease Sinceitisadifficultdiseasetocure ,itattractstheattentionofmanyresearchers Recentstudiessuggestthatimmunocompetencesubstancespresentinthehumanbodyareimportantfactorsinphysiologicalfunctionanddemonstratethatel…  相似文献   

10.
TGF-β1基因转染修饰人退变腰椎间盘髓核细胞   总被引:1,自引:0,他引:1  
Degenerationofthelumbardiscaffectsthemechanicalpropertiesofthespineandisrelatedtoclinicallowbackdisorders Thelimitedavailabletechnologygenerallyishighlyinvasiveandusuallydiscectomyisinvolved ,whichoftencompromisesthestructuralintegrityofthespine Longte…  相似文献   

11.
Transplantationofpancreaticisletoflangerhansisarapidlygrowingareainmedicalresearchwithapromiseofclinicalapplication1 Themajorprogressesareasfollows:1microencapsulationdonorisletforimmunoisolationavoidtheacuterejection,butthechronicrejectionandinnutriti…  相似文献   

12.
Expertspredictthatlifescienceswillbedevelopedbyleapsandboundsinthe21stcenturyWiththeextensiveapplicationofhighandnewtechniquesandcontinuouspenetrationofmolecularbiology,manyprojectssuchaswoundhealingandtissuerepairinthefieldofsurgeryarefacinggreatchal…  相似文献   

13.
Carcinoidtumorshavebeenfoundinvariousorgansofthebody,especiallyinthegastrointestinalandrespiratorytracts Carcinoidtumoroftheepididymisisespeciallyrare Wedescribehereacaseofprimarycarcinoidtumoroftheepididymisthatwasdetectedbyaccidentinapatientwhounder…  相似文献   

14.
TheresearchgroupledbyProfessorWuYiminghasbeenengagedintheresearchofprofessionaltumorformanyyears ,especiallyengagedintheresearchofcharacteristicsoflungtumorcausedbypolyaromaticcompounds ,carcinogen esismechanismandtheresearchofearlydiagnosisofprofessio…  相似文献   

15.
HYPERTENSION PREVALENCE   总被引:1,自引:0,他引:1  
Hypertensionisthemaincauseofstrokeandanimportantriskfactorofcoronaryheartdisease-Itisalsothemostcommonunderlyingcauseforcongestiveheartfailure-InChinacardiovasculardiseasesaccountforthelargestnumberofdeathsandstrokealonerankssecond,thatisonlynexttoca…  相似文献   

16.
Objective Toinvestigatethediagnosticsignificanceoftotalrespiratoryimpedanceforchronicobstructivelungdisease-Methods Theimpedanceofrespiratorysystemwasmeasuredbyimpulseoscillometrymethodandcomparedwithparametervaluesofroutinepulmonaryfunctionin57patie…  相似文献   

17.
Theuterinecavitycommunicateswiththeexternalenvironmentandisthereforeexposedtoforeignantigens Itdoesnothaveacomplexstructureoflymphnodesandretainsthecharacteristicsofaprimitivesurfaceepithelia 1Previousstudieshavedemonstratedthepresenceoflymphocytesint…  相似文献   

18.
Hemostasis and thrombosis research in China   总被引:1,自引:1,他引:0  
Hemostasisandthrombosisisadisciplinecombiningvariousaspectsofbasicbiologyandmedicine-Itdealswithmainlyfundamentalandclinicalresearchfortheoriginofbleedingdisordersandthromboticdiseaseswhicharesoharmfultohumanhealth-Hemostaticabnormalitiesandthrombosi…  相似文献   

19.
IntraditionalChinesemedicine,thetermorganpicturereferstovisceraloutwardmanifestationsandcarrieswithittheimplicationsofphysiologyandpathology,theclinicalpathologicalchangesofwhichiscalled“syndrome”-Thesyndromeisnotmerelyacollectionofsymptomsandsigns;i…  相似文献   

20.
Objective Toestablishadiagnosticcriteriaofparasystolewithhighsensitivityandhighspecificity-Methods Afterexcludedfromnonparasystoleandeachvariantparasystoles,basedontheelectrocardiographicdataobtainedfrom61patientswithclassicparasystole,weselectedtheq…  相似文献   

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