鼻内镜手术治疗鼻腔及鼻窦内翻性乳头状瘤36例分析

目的 探讨鼻腔及鼻窦内翻性乳头状瘤的临床特征、鼻内镜手术方法 及临床疗效.方法 对2005年5月2010年7月36例鼻腔及鼻窦内翻性乳头状瘤的临床资料进行回顾性分析.结果 全部病例随访1～3年,无一例并发症,32例一次性治愈,复发4例,经再次手术后治愈.结论 鼻内镜手术清除病灶是治疗鼻腔及鼻窦内翻性乳头状瘤的最有效方法,手术中应尽量扩大鼻窦的自然开口,手术后定期冲洗窦腔及定期复查可防治疾病的复发.     

鼻内镜下泪前隐窝入路治疗上颌窦内翻性乳头状瘤的疗效分析

目的 探讨鼻内镜下经泪前隐窝入路(即鼻腔外侧壁入路)手术治疗上颌窦内翻性乳头状瘤的疗效及并发症。 方法 回顾性分析2014年9月至2016年3月收治的21例内翻性乳头状瘤的临床资料。 结果 21例患者通过鼻内镜经泪前隐窝入路手术治疗上颌窦病变,术中均完全清除窦内病变,且术中、术后病理证实为内翻性乳头状瘤。术后愈合良好,无严重并发症。1例患者术后6个月局部复发,再次手术切除,现随访12个月无复发。 结论 经泪前隐窝入路进入上颌窦切除病变是一种微创、安全、有效的处理内翻性乳头状瘤的手术方式。     

Surgery of inverted papillomas under endoscopic control

Six centers cooperated in a retrospective study on endoscopic surgical resection of Papillomas of the nose and paranasal sinuses in order to assess both the efficiency and the safety of this kind of surgical approach. From 1991 till march 2000, 87 cases of Papillomas resections under--at least partially--endoscopic control were gathered, among which 85 were Inverted Papillomas (IP), 2 were Exophytic Papilloma (EP) and one was IP coexisting with Collumnar Cell Papilloma (CCP). Malignant transformation was found out in 3 cases of IP. Regarding the 85 patients with IP demographics are as follows: 61 males, 24 females, with a mean age of 58.4 years (STDV: 13.96) in a range from 27 to 92 years. The mean follow-up was of 41.9 months with range of 1-120 months. Fifteen recurrences occurred that were treated by revision surgery either under endoscopic control or by limited external approach. The mean time for recurrences to occur was 8.07 months with range of 1-24 months. The three patients with malignant transformation underwent postoperative radiation therapy. All of the patients are free of recurrence, however for some of them the follow-up is too short to definitely assess their free of disease status. The role of modern diagnostic tools in medical imaging--CAT and MRI--in order to assess clearly the limits of the tumors and to enhance the efficiency and the safety in the choice of a surgical approach is pointed out. The stress is put on the need for radical excision under endoscopic control which can be combined with the Caldwell-Luc transantral approach or with frontal trepanation for the cure of tumors impossible to be reached under endoscopic control only. Irrespective of the tumor extent and of the approaches that was used for excision a close endoscopic follow-up still remain mandatory, by trained surgeons, in the long term management of IP. Biopsies, CAT and/or MRI must be performed in any case with recurrence suspicion.     

The endoscopic management of sinonasal inverted papillomas

Sinonasal inverted papillomas are well known for high recurrence rates after surgery and the risk of malignant change. Recurrent disease occurs because of inadequate excision as a result of poor exposure and visualization. For these reasons, aggressive surgery has been advocated-classically a lateral rhinotomy and en bloc medial maxillectomy. Endoscopic techniques have provided excellent visualization and a less invasive approach to these tumours. We describe 18 patients with inverted papillomas treated endoscopically at the Singapore General Hospital since 1993. The presentation, sites of involvement and diagnostic imaging are presented. All the patients had a minimum follow-up of 18 months with a mean of 32.8 months. One case of recurrence at the frontal recess is reported. Endoscopic management is appropriate for the diagnosis, follow-up and treatment of circumscribed primary and recurrent inverted papillomas.     

鼻内翻性乳头状瘤内镜手术分析

目的　探讨内镜鼻内翻性乳头状瘤手术疗效及安全性。方法　回顾性分析2004年10月～2011年12月27例鼻内翻性乳头状瘤内镜手术患者临床病例资料。结果　术后乳头状瘤病灶残留1例,1个月后行二次手术。术后随访24～116个月,复发4例均再次手术,其中恶变1例为蝶窦内翻性乳头状瘤。癌变患者予以根治性放疗,随访36个月未见复发及转移。结论　鼻内镜下切除鼻内翻性乳头状瘤安全、有效,与传统手术相比并不增加复发率,但创伤小。残留病灶宜尽早二次手术。术后随访内镜检查是明确有无复发的重要手段。     

Endonasal endoscopic surgical treatment of paranasal sinus inverted papilloma--first experiences.

PURPOSE: Surgical excision is generally regarded as the treatment of choice for inverted papilloma. However, the approach and extent of surgery has been subject of much debate. The purpose of this study is to evaluate the results of endoscopic sinus surgery in the treatment of paranasal sinus inverted papilloma. PATIENTS AND METHODS: Thirteen cases of inverted papilloma of the paranasal sinuses treated via endoscopic sinus surgery were evaluated. The follow-up averaged from 9 months to 48 months with a mean of 27 months. RESULTS: A close follow-up of all patients was maintained. Seventy-seven per cent (10/13) of the patients had no recurrence after the initial endoscopic procedure. Three patients had recurrences of their tumor within 11 months after surgery, which means a rate of 23% (3/13). In 2 patients, the recurrences were treated endoscopically. In one patient, recurrence and malignant transformation (squamous cell carcinoma) developed after 36 months, which means that the associated carcinoma rate was 7% (1/13). This patient underwent radical maxillectomy and postoperative radiotherapy. None of the patients died of inverted papilloma. CONCLUSION: Endoscopic sinus surgery is a viable treatment alternative for paranasal sinus inverted papilloma in selected cases. This approach should be performed by experienced surgeons and a close follow-up is mandatory. When the disease is more extensive, it should be approached by radical surgery, e.g. en-bloc excision by medial maxillectomy via lateral rhinotomy or mid-facial degloving.     

鼻内镜下鼻内翻性乳头状瘤切除术(附46例报告)

目的:总结鼻内翻性乳头状瘤的临床特点,探讨鼻内镜手术切除鼻内翻性乳头状瘤的疗效。方法:对1995~2005年收治的46例鼻内翻性乳头状瘤患者施行鼻内镜手术。结果:46例患者均在鼻内镜下完整切除肿瘤(其中8例联合上颌窦根治术),随访12~72个月,5例术后24个月内复发,其余41例在随访期内未见复发。结论:鼻内镜手术治疗鼻内翻性乳头状瘤是一种安全有效的方法,对肿瘤广泛侵及上颌窦内的Ⅲ级病变联合上颌窦根治术效果较好。     

鼻内镜下鼻腔鼻窦内翻性乳头状瘤切除术

目的:探讨鼻内镜下鼻腔鼻窦内翻性乳头状瘤切除术的疗效及应用价值.方法:回顾性分析1999年7月～2005年4月诊治的有完整随访资料的40例经鼻内镜手术治疗的鼻腔鼻窦内翻性乳头状瘤患者的临床资料.结果:所有病变均一次完全手术切除,5例患者接受术后放疗.无严重并发症发生.术后随访24～93个月,平均45.1个月,6例复发,其中3例恶变,3例死亡.复发时间18～58个月,平均37.3个月.结论;经鼻内镜手术治疗鼻腔鼻窦内翻性乳头状瘤安全、有效、微创,彻底切除肿瘤、术后定期随访是治疗成功的关键.     

The endoscopic management of sinonasal inverted papillomas 1

Sinonasal inverted papillomas are well known for high recurrence rates after surgery and the risk of malignant change. Recurrent disease occurs because of inadequate excision as a result of poor exposure and visualization. For these reasons, aggressive surgery has been advocated–classically a lateral rhinotomy and en bloc medial maxillectomy. Endoscopic techniques have provided excellent visualization and a less invasive approach to these tumours. We describe 18 patients with inverted papillomas treated endoscopically at the Singapore General Hospital since 1993. The presentation, sites of involvement and diagnostic imaging are presented. All the patients had a minimum follow-up of 18 months with a mean of 32.8 months. One case of recurrence at the frontal recess is reported. Endoscopic management is appropriate for the diagnosis, follow-up and treatment of circumscribed primary and recurrent inverted papillomas.     

Surgical management of sinonasal inverted papillomas through endoscopic approach

We defined a standardized approach to surgery of sinonasal inverted papillomas (IP) for adequate and safe resection. A cohort of 65 patients treated from January 1995 to December 2005 at a single institution was retrospectively analyzed (mean follow-up: 28 months; range 1–132). The extension of the tumor was evaluated on clinical findings and computed tomography (CT) scan and/or resonance magnetic imaging (RMI). External and endoscopic surgical approaches were compared according to tumor extension, rate of local recurrence. Univariate analysis was used to review the impact on disease-free survival of factors related to the histopathological findings and the treatment. Endoscopic (alone or combined with transantral approach) and external surgery were used in 46 patients (71%) and 19 patients, respectively. Endoscopic approach (34/46) was performed to control IP in the nasal fossa, the ostiomeatal complex, the sphenoid sinus. It was combined with Caldwell-Luc procedure (12/46) for tumor extent into the lateral part of the maxillary sinus. The mean time for recurrences to occur was 19 months with range of 5–35 months. The rate of local recurrence was 17.6% (6/34) in endoscopic approach alone, 8.3% in endoscopic approach combined with a Caldwell-Luc procedure and 15.8% (3/19) in external approach. Tumor extension, excision with safe margins, associated malignancy or dysplasia have no significant impact on disease-free survival regardless of surgical procedure. On the basis of imaging evaluation and peroperative view of tumor extent, we propose a surgical strategy in which endoscopic approach could be used on the first attempt by trained surgeons. RMI is very useful to determine acute extent of the disease.     

Adenoidectomy vs endoscopic sinus surgery for the treatment of pediatric sinusitis.

OBJECTIVE: To compare endoscopic sinus surgery with adenoidectomy for the treatment of refractory chronic sinusitis in children. STUDY DESIGN: Prospective nonrandomized study in a pediatric otolaryngology service of a university teaching hospital. PATIENTS AND METHODS: Sixty-six children consecutively referred to the pediatric otolaryngology service between 1994 and 1997 with computed tomographic documentation of sinusitis subsequently underwent endoscopic sinus surgery or adenoidectomy. Their ages ranged from 2 to 14 years. Sixty-one children received follow-up. Two main outcomes were documented: (1) symptom status at least 6 months after the intervention and (2) requirement of the alternate procedure or a revision procedure. RESULTS: Twenty-four (77%) of 31 children who underwent endoscopic sinus surgery had improved symptoms, compared with 14 (47%) of 30 children who underwent adenoidectomy (odds ratio [OR], 3.9; P = .01). Multivariable analysis demonstrated that endoscopic sinus surgery was significantly better than adenoidectomy after age, sex, allergy, asthma, day care attendance, and computed tomographic stage were adjusted for (OR, 5.2; P = .03). The diagnosis of asthma also appeared to be an independent predictor of success (OR, 4.37; P = .03). CONCLUSION: Endoscopic sinus surgery is better than adenoidectomy for the treatment of refractory chronic sinusitis in a select group of children.     

Evolution of endoscopic surgery in the treatment of inverted papilloma

Inverted papilloma (IP) has several treatment avenues. The endoscopic approach in the last decade has proven to be a good option over the traditional approach.ObjectiveDescribe the epidemiological profile of patients with inverted Papilloma, describe our experience on managing this tumor and compare our data with the literature. Study Design: Cross-sectional, historical cohort.MethodRetrospective study of medical records of 17 patients treated for histopathologically-confirmed inverted papilloma between 2005 and 2011. We assessed patients age, gender, tumor side, symptoms, diagnosis, comorbidities and habits, Krouse staging, surgical approach, intraoperative and postoperative, and malignant postoperative recurrence and also the correlation between recurrence with preoperative staging, the surgical approach used, and the presence of malignancy.ResultsFive (29.41%) patients were classified as Krouse stage T2, 9 (52.94%) as T3 and 3 (17.65%) as T4. Three (17.65%) patients had malignancy and the recurrence rate was 23.5% (4 pacients). Eleven patients (64.70%) underwent endoscopic approach, 3 (17.6%) the combined aprroach (endoscopic assisted) and 3 (17.6%) external approach.ConclusionThe endoscopic approach is currently becoming a method not only effective but also safe for the treatment of more advanced stages of IP.     

Microscopic rhinoscopy in the treatment of inverted papillomas

Inverted papillomas are endophytic lesions arising from tissues in the nose and paranasal sinuses noted for their local destruction, propensity to recur, and tendency for malignant transformation. It has been well documented that complete removal is essential in the prevention of recurrence; however, use of the operating microscope to ensure this has not been widely described in the past. We present 4 patients, ages 36 to 56, for whom the operating microscope was used intra-operatively and for follow-up examinations. The patients have been followed for 1 to 5 years without any evidence of recurrence to date. We submit that the operating microscope is an extremely valuable tool for the surgical treatment of this lesion in light of the absolute necessity for its complete removal.     

Preoperative magnetic resonance imaging for localization of the origin of maxillary sinus inverted papillomas

Purpose

It is essential to precisely localize the origin of an inverted papilloma within the maxillary sinus by preoperative imaging so that the lesion can be excised as thoroughly as possible. In the present study, we evaluated the use of preoperative magnetic resonance imaging (MRI) for pinpoint localization of the origin of inverted papillomas.

Materials and Methods

The subjects were patients with an inverted papilloma of the maxillary sinus. Given the known histopathological features and pattern of growth of this tumor, we obtained preoperative MRIs in an attempt to localize its origin.

Results

When different interpretation methods were applied to the preoperative MRIs, there was up to an 85.7% correlation with the surgical results for localization of the tumor origin.

Conclusions

We were able to demonstrate a high rate of agreement between diagnostic imaging and the actual surgical findings in identification of the origin of inverted papillomas.     

Anatomy for endoscopic sinus surgery

An understanding of the anatomy of the paranasal sinuses is essential for successful endoscopic sinus surgery. The anatomy of the sinuses is carefully described and illustrated.     

Image-guidance for endoscopic sinus surgery

Objectives/Hypothesis: Image‐guided surgery (IGS) is a critical tool. However, its clinical validity remains controversial. A review of indications and a consensus based on literature are presented. Methods: Literature review. Results: Traditional indications remain valid. Novel applications have emerged, and the reliability of IGS has been consistently endorsed. Although evidence is based on scattered reports and expert opinions, the use of IGS in approved instances is regarded as the state of the art. Conclusions: IGS is reliable, and a scientific validation of outcomes would entail unethical strategies. An expanding spectrum of indications is anticipated, although IGS does not replace proper training.