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1.
目的:探讨南宁市胆石病19年(1981~1999年)来的变化。方法:采用回顾性调查的方法收集2 252例胆石病患者的临床资料,进行比较分析。结果:南宁市胆石病前10年(1981~1999年,A组)与后9年(1991~1999年,B组)比较,男女比例为1:1。2;年龄峰值在51~60岁;职业以农民居多,A、B两组分别占46.3%及34.0%;结石部位以胆囊结石最多(34.6%),其次是肝内胆管结石(  相似文献   

2.
本文收集了1991年11月 ̄1992年4月武汉市武昌区甲型肝炎流行期间体检人员2501例,进行了甲型肝炎抗体IgM(抗HAV-IgM)的检测,抗HAV-IgM的检测用ELISA法,抗HAV-IgM阳性率为21.2%,其中男性为21.8%,女性为20.4%,两性间差异无显著性(P〉0.05),1.5 ̄10岁年龄组中男孩40.0%显著高于女孩30.6%;21 ̄50岁随着年龄增大阳性率逐渐增高,50岁以  相似文献   

3.
本文分析49例C-ITP骨髓巨核细胞的质和量,与15例对照组比较,探讨其变化机理。5例巨核细胞数为23 ̄35个/全片,44例为36 ̄522个/全片;平均34.99个/cm^2。对照组平均为10.89个/cm^2(P〈0.05)。49例中,幼巨占2% ̄16.7%(平均6.59%),颗巨63% ̄94%(79.5%),产板巨0 ̄20.2%(6.85%),显示核象左移。巨核细胞增多是由于骨髓代偿性增生,和  相似文献   

4.
1987年1月至1996年12月,我院内镜室经纤维结肠镜共检出大肠息肉476例,现分析如下。1临床资料本组476例,男291例,女185例,男女之比1.57∶1,病程2天~30年,年龄3~78岁(平均45岁),年龄分布:3~10岁4例(0.84%);...  相似文献   

5.
为了探讨急性淋巴细胞白血病患儿免疫球蛋白重链基因重排的临床价值,应用多聚酶链反应技术检测25例B-ALL患儿IgH基因。结果表明,25例中19例在初诊或复发时检出克隆性重排,并对此19例随访观察48次,平均随访时间为11.2月(2 ̄25月)。IgH-PCR预测ALL复发率为58.8%,占复发病例的80%,阳性克隆检出时间先于形态学复发的平均时间为10.3周(1 ̄28.8周)。本方法敏感性0.5%,  相似文献   

6.
作者对57例年龄在3个月内息巨细胞病毒(CMV)肝炎的婴儿,分组进行干扰素(IFN)治疗观察。治疗组(n=30)在用静脉VitC加肌苷的基础上加用γ-IFN10 ̄6u/d肌注,连续10天。对照组(n=27),单用静脉VitC加肌苷,连续10天。其后两组病人均口服VitC、肌苷至一个月。结果显示,γ-IFN治疗组与对照组比疗效有显著性差异。黄疽消退平均提前15.26天(P<0.005);肝脏肿大恢复正常提前29;89天(P<0.001),SGPT恢复正常,平均提前14.26天(P<0.01)。两组在1个月及2个月的痊愈率分别为43.0%、18.5%及90.O%、48.O%(P<0.05)。  相似文献   

7.
广西10县市1990—1992年儿童意外死亡原因分析   总被引:2,自引:0,他引:2  
目的:意外死亡是儿童主要死因之一,分析儿童意外死亡的原因,为制订预防措施提供科学依据很有必要。方法:在广西10个全死因调查的样本县中,统计0 ̄14岁儿童死亡的病例,计算各年龄组意外死亡原因和进行意外死亡性别比较(X^2检验)。结果:0 ̄14岁儿童意外死亡的死亡率为54.5/10^5,位于全死因中的第三位。前三位死因分别为淹死(49.2%)、交通事故(10.3%)和跌落(6.0%)。男童意外死亡的5  相似文献   

8.
在0.10mol·L ̄(-1)盐酸-0.40mol·L ̄(-1)六次甲基四胺-5.0×10 ̄(-3)mol·L ̄(-1)邻菲啉-5.0×10 ̄(-3)mol·L ̄(-1)硫氰酸钾底液中用示波极谱法测定铅的方法,峰电位为-0.70V(VS,SCE)左右,线性范因为0.04-1.6μg·ml ̄(-1),检出限为0.008μg·ml ̄(-1)。该方法简便、快速、选择性好,直接应用于人发中铅的测定;变异系数为2.4-5.9%;样品加标回收率为97.4-105%。  相似文献   

9.
对1986年10月 ̄1993年10月青岛地区低出生体重儿2724例进行了监测。结果表明,低出生体重儿发生率为4.45%,早产是低出生体重的重要原因(占54.85%);其它原因是孕龄≤20岁(发生率8.42%)及〉35岁(7.83%),母亲职业为农民(发生率5.34%)及个体经商者(8.80%),母亲疾病、胎儿畸形(发生率107.6‰)。低出生体重儿围产期死亡率为252.2‰,探讨了预防低体重儿发生  相似文献   

10.
叶下珠复方治疗慢性乙型肝炎54例临床观察   总被引:2,自引:0,他引:2  
应用叶下珠复方治疗慢性乙型病毒性肝炎54例,与灭澳灵10例作对照。结果显示叶下珠复方组治疗3个月(其中10例治疗6个月),临床症状体下显著改善,肝功能复常或明显改善者达82.6%;e抗原及HBV-DNA转阴率分别为46.2%(24/52)和46.3%(19/41);疗效优于灭澳灵组(上述3项指标分别为20%,10%,10%;P〈0.01和P〈0.05)。叶下珠复方组治疗3个月后e抗的及DNA示阴转  相似文献   

11.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

12.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

13.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

14.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

15.
Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P<0.01);the MAP decreased(P<0.01)and the HR increased drastically(P<0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.  相似文献   

16.
Objective:To investigate the gene expression of osteoprotegerin(OPG) and osteoclast differentiation factor(ODF) in the bone tissue of patients with hip fracture due to osteoporosis. Methods:OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers(over 50 years old) with hip fracture(Observer Group) and 30 cases of hip facture sufferers with no osteoporosis(Control group) were analyzed with the Semi-Quantitative RT-PCR method. Results:The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion:Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

19.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

20.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

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