共查询到20条相似文献，搜索用时 31 毫秒
1.
2.
Matthew D. Benson Julianna Wozniak Ian M. MacDonald 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):94-97
Objective
To report the reoperation rate in a large group of pediatric and adult strabismus patients over a 21-year period in Northern Alberta, Canada.Methods
A retrospective review of 6177 strabismus surgeries from July 1995 to June 2015 on 5125 pediatric and adult patients was conducted to determine the reoperation rate at a single major referral centre. A set of guidelines was implemented in November 2014 recommending delaying reintervention for at least 12 weeks from the initial surgery, with specific exceptions.Results
The historical strabismus reoperation rate over a 21-year period was 15.7%. Of those surgeries requiring reoperation, 77.7% required only 1 reoperation, 17.1% required 2 reoperations, 3.1% required 3 reoperations, and 2.1% required 4 or more reoperations. The mean time between surgeries for patients undergoing reoperation was 2.3 years and the median time was 1.0 years.Conclusions
Our study provides insight into the strabismus reoperation rate and the number of subsequent surgeries performed for patients over a 21-year period. Although preoperative ocular alignment, comorbidities, and the status of the operative eye modify the probability of reoperation, our results from a large cohort of patients provide an impression of the rate of reoperation and may be of benefit in the preoperative counseling of patients. Furthermore, we highlight the scarcity of guidelines for the appropriate timing of reoperation. The implementation of specific guidelines may encourage future investigation into trends in reoperation over time and promote ways to avoid unnecessary surgeries, lower health care costs to stakeholders, and ultimately improve patient care. 相似文献3.
Suresh Sagili Jerome Ha 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):98-101
Objective
To describe a modification of trans-conjunctival, lower eyelid retractor advancement to correct tarsal ectropion.Design
A retrospective case review.Participants
Consecutive patients with lower eyelid tarsal ectropion.Methods
Cases of lower eyelid tarsal ectropion, surgically corrected by advancement of inferior retractor to the lower border of tarsus via a transconjunctival approach, were identified. Lateral tarsal strip was also performed simultaneously in all cases.Results
Twenty patients (25 eyelids) were included in this study. There were 19 primary lower eyelid tarsal ectropion and 6 recurrent tarsal ectropion. Complete resolution of tarsal ectropion was achieved in all patients postoperatively. Mean follow-up was 8.4 months (range 1–36 months). There were no cases of overcorrection, recurrent ectropion, suture abscess, wound dehiscence, or inferior fornix shortening after surgery.Conclusions
Visualization of the lower eyelid retractor (white-line) and advancement to the inferior border of tarsus through a transconjunctival approach is effective in correcting both primary and recurrent cases of tarsal ectropion. This can be performed through a small conjunctival incision in the middle third of the lower eyelid, without the need for any excision of tissue or suture loop tie on the skin surface. 相似文献4.
5.
Natalie H. Au Rookaya Mather Alison To Monali S. Malvankar-Mehta 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(2):180-189
Objective
To summarize and quantitatively evaluate sleep outcomes of dry eye disease (DED) patients.Design
A systematic review and meta-analysis.Participants
DED patients were individuals with dry eye symptoms or primary Sjogren’s syndrome (pSS). Controls were healthy, non-pSS, or non-DED patients.Methods
A systematic search of MEDLINE, EMBASE, PsycINFO, and grey literature was conducted. Studies were screened using Covidence software. Outcomes included sleep quality, duration, daytime sleepiness, prevalence/incidence/severity of sleep disorders, and sleep disturbances. Meta-analysis was conducted using STATA 13.0. The weighted mean difference (WMD) was calculated as the effect size for continuous scale outcomes. Random-effects models were developed based on the presence of heterogeneity.Results
Seventeen full-text articles (16 370 subjects) and 2 conference abstracts (571 763 subjects) were included. Compared to controls, DED patients score higher on the Pittsburgh Sleep Quality Index (WMD = 1.69, 95% CI: 0.82, 2.56; I2 = 88.8%, p < 0.001) and Epworth Sleepiness Scale (WMD = 2.26, 95% CI: 0.96, 3.56; I2 = 82.4%, p < 0.001). Additionally, DED patients spend less time asleep (WMD = ?0.59 hours, 95% CI: ?0.94, ?0.24; I2 = 85.1%, p < 0.001), experience more sleep disturbances, and may have increased prevalence, incidence, severity of sleep disorders.Conclusion
DED patients may have poorer sleep quality, greater daytime sleepiness, less sleep, more sleep disturbances, increased prevalence, incidence, and severity of sleep disorders compared to non-DED patients. Further research is needed to identify potential causes of these outcomes given the paucity and heterogeneity of included studies. It may be worthwhile to consider sleep in the clinical management of DED. 相似文献6.
Jianxin Ni Xi Chen Shengjie Zhou Jia Liu Ben Chen 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):102-105
Objectives
To investigate the outcomes for correction of involutional lower eyelid entropion by wedge resection of the tarsus combined with the modified Hotz procedure.Design
Retrospective study.Participants
Patients with lower eyelid involutional entropion that was surgically repaired by wedge resection of the tarsal plate combined with the modified Hotz procedure.Methods
In a consecutive series of 43 patients with involutional lower eyelid entropion, wedge resection combined with the modified Hotz procedure was performed with an average follow-up period of 29.6 months (range, 6–62 months).Results
Among the patients, 93% had an excellent outcome within the follow-up period. For one patient, the outcome of both eyes was poor. For another patient, incision dehiscence of the eyelid margin in one eye occurred after the stitches were removed. The incision was sutured again, and it healed well. One patient complained of foreign body sensation in one eye after removal of the skin stitches. The complaint was resolved after wearing a corneal contact lens. No other significant complications occurred.Conclusions
In our clinic, tarsal plate wedge resection combined with the modified Hotz procedure has been highly effective for correction of involutional lower eyelid entropion. Although this approach does not directly address lateral canthal tendon laxity, it does preserve the eyelid in case there is a future need for reconstruction due to ocular surface disease or trauma. Thus, wedge resection of the tarsal plate combined with modified Hotz procedure is a safe and effective method for involutional lower eyelid entropion. 相似文献7.
Parampal S. Grewal Steven R.J. Lapere R. Rishi Gupta Mark Greve 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):60-64
Objective
To determine the effectiveness of a macular buckle procedure without vitrectomy for the treatment of symptomatic myopic macular schisis.Design
Retrospective case series.Participants and methods
All patients who underwent surgery with placement of an NPB macular buckle (AJL Ophthalmic, Miñano, Álava, Spain) without vitrectomy for symptomatic myopic macular schisis were included. Visual acuity and anatomical outcomes based on optical coherence tomography (OCT) were reviewed.Results
Eight consecutive eyes from 7 patients were included. Six of the 7 patients were female and the mean age was 59 ± 6 years (range, 49–66 years). The mean follow-up duration was 11 ± 7 months (range, 3–23 months). Mean preoperative axial length was 29.54 ± 1.28 mm (range, 27.88–31.96 mm). Mean preoperative best-corrected visual acuity (BCVA) was 0.71 ± 0.29 logMAR (Snellen equivalent 20/103); mean postoperative BCVA was 0.46 ± 0.44 (Snellen equivalent 20/58; p = 0.19) and 87.5% of patients maintained or improved vision. Pre- and postoperative OCT images are included and discussed within. Preoperative ellipsoid zone status and postoperative central macular buckle indentation appear to be important in visual outcomes. Two patients required a buckle repositioning for persistent schisis. One patient developed a macular hole postoperatively that resolved with subsequent vitrectomy. There were no other complications.Conclusions
The macular buckle is an effective and promising therapeutic option for myopic macular schisis. 相似文献8.
Amy Basilious Alfred Basilious Alex Mao Cindy M.L. Hutnik 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(2):229-236
Objective
Little is known about how low vision services by ophthalmologists are being provided. Here, we analyze the patterns of provision and utilization of vision rehabilitation services in Ontario, Canada.Design
Retrospective population-based study between 2009 and 2015.Participants
Ophthalmologists (n = 92) who billed for vision rehabilitation services through the Ontario Health Insurance Plan in Ontario and the patients (n = 8949) who received these services.Methods
Billing data for low vision services (2009–2015) was received from Ontario Health Insurance Plan. Data were analyzed to describe patient demographics (age, sex, geographic distribution, number, and type of visits) and service provider information (geographic location, number of years providing services, and number of services per year).Results
It is estimated that ≤ 5% of patients with low vision in Ontario accessed these vision rehabilitation services by ophthalmologists. The majority of these patients were females (61%) and > 60 years old (79%). While patient and provider geographic distributions overlapped in the areas with largest patient populations, many regions lacked services. The majority of patients (71%) made only one vision rehabilitation visit. Nine providers practiced low vision for 7 years, while 43 provided services for only 1 year. In 2015, the most common diagnostic service provided to low vision patients was Optical Coherence Tomography of the retina and the most common therapeutic service was intravitreal for wet age-related macular degeneration.Conclusion
Although low vision services increased between 2009 and 2015, there were differences in ability to access care based on age, sex, and geographic location. 相似文献9.
Min Joung Lee In Hyuk Kim Youn Joo Choi Namju Kim Ho-Kyung Choung Sang In Khwarg 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):111-115
Objective
To analyze the relationship among the presence of lacrimal sac mucus retention, the vertical size of the lacrimal sac, and the duration of tearing symptom in patients with nasolacrimal duct obstruction (NLDO).Design
Retrospective case series.Participants
We reviewed the medical records of 473 patients (664 eyes) who underwent external dacryocystorhinostomy for primary NLDO.Methods
The information about the presence of lacrimal sac mucus retention and vertical size of the lacrimal sac lumen was collected intraoperatively. The vertical size of the lacrimal sac was classified into 3 groups: small (<5 mm), medium (5–10 mm), and large (>10 mm). The relationship between the lacrimal sac size, presence of mucus retention, and duration of tearing was analyzed.Results
Of the 664 eyes, 138 had a small lacrimal sac, 199 had a medium lacrimal sac, and 327 had a large lacrimal sac. The distribution of the lacrimal sac size groups differed significantly between the eyes with (n = 245) and without (n = 419) mucus retention (p < 0.001). Among all the subjects of each lacrimal sac size group, there was no significant difference in the duration of symptoms (p = 0.176). However, in patients without mucus retention, the symptom duration in the small lacrimal sac group was significantly longer than that in the large lacrimal sac group (p = 0.017).Conclusions
In cases with mucus retention, a small lacrimal sac is rare. In cases without mucus retention, the duration of tearing symptom was significantly longer in small lacrimal sac group. 相似文献10.
Cyril Archambault Caroline Gabias Nicole Fallaha Caroline Bélanger Rosanne Superstein 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):83-86
Background
Ocular traumas represent the most common cause of noncongenital blindness in children. Sports are the second most common cause in children less than 14 years old in Canada. To our knowledge, there have not yet been any reports regarding the causes of pediatric ocular trauma in the Quebec population. The goal of our study was to gather data from the Quebec pediatric population to determine high-risk age groups, sports, or other activities.Methods
A retrospective study evaluating all patients younger than 18 years who presented with ocular trauma to the Ste-Justine Hospital emergency department between 2007 and 2010. Data obtained included age, sex, activity at the time of injury, mechanism of injury, and visual outcomes.Results
Trauma was more common in males (65%). The mean age was 7.2 years. Injuries occurred more often in the 5–9 year age group, at home, and during free play. Sports-related injuries occurred more often in the 10–18 year age group, with hockey being associated most often with injuries. Visual acuity at presentation was variable, but final acuity was 20/30 or better in 86.7% of cases. In 89% of cases, there was no mention of ocular protection and prevention of injuries in the chart by emergency physicians.Conclusion
Our study suggests that ocular injuries may be prevented by better supervision and parental education in the younger population and by mandating ocular protection for sports in high school–aged patients. 相似文献11.
Ali Küçüködük Fatma Helvacioglu Nihan Haberal Attila Dagdeviren Didem Bacanli Gursel Yilmaz Imren Akkoyun 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):65-74
Objective
To evaluate the impact of intravitreal (IV) and intraperitoneal (IP) astaxanthin (AST) injections on neovascular development (ND), retinal morphology, and apoptotic activity in a C57BL/6J mouse model with hyperoxia-induced retinopathy (HIR).Design
C57BL/6J mouse model.Methods
Two negative control groups (n = 6 each; one of which received IV sterile dimethyl sulfoxide [DMSO]) of C57BL/6J-type mice were exposed to room air. The HIR groups included 36 C57BL/6J-type mice exposed to 75% ± 2% oxygen from postnatal day (PD) 7 to PD 12. On PD 12, these mice were randomized into 6 groups (n = 6 each): 2 HIR control groups (one of which received IV-DMSO), 2 IV-AST groups (10 and 100 µg/mL), and 2 IP-AST groups (0.5 and 5 mg/kg). We measured ND by counting neovascular tufts in cross sections and examined histological, ultrastructural changes via light and electron microscopy. Apoptosis was detected using terminal deoxynucleotidyl transferase–mediated nick end-labeling.Results
No ND was detected in the negative control groups. ND levels were not significantly different between high- and low-dose AST for either means of administration. However, ND levels were significantly lower in the AST groups, regardless of delivery, compared to the control groups. The means of delivery (IP versus IV) also yielded significant differences in ND. The incidence of mitochondrial dysmorphology and apoptosis were lower in groups receiving AST.Conclusions
AST seems to suppress ND and has anti-apoptotic activity in the HIR mouse model. 相似文献12.
Tarek Ibrahim Phillip Goernert Guillermo Rocha 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):130-135
Objective
To report the intraoperative surgical outcomes and safety of femtosecond laser–assisted cataract surgery (FLACS) during surgeon learning curve and compare those outcomes with those of conventional phacoemulsification in a Canadian public hospital setting.Design
Retrospective chart review.Participants
FLACS and phacoemulsification patients at Brandon Regional Health Centre, Brandon, Manitoba, Canada.Methods
Intraoperative surgical outcomes and safety (rates of intraoperative complications and phacoemulsification parameters) were compared among 3 groups: the first consecutive 197 cases using femtosecond laser (FSL) pretreatment to ultrasound phacoemulsification in cataract surgery (group 1; early FLACS), the second consecutive 165 cases using FSL (group 2; later FLACS), and 80 consecutive conventional cataract surgery cases (group 3; conventional phaco).Results
There was a statistically significant difference for phacoemulsification parameters (actual phaco time [APT], effective phaco time [EPT], and ultrasound average) among the 3 groups (all p-values < 0.05). The mean phacoemulsification parameters (APT and EPT) for the early FLACS and the conventional phaco groups were significantly longer than those for the later FLACS group (p < 0.05). The mean FSL time for the early FLACS group was significantly longer than that for the later FLACS group. There was no statistical difference among the rates of intraoperative complications (suction breaks, capsular tags, FSL-induced miosis, posterior capsular tears, and anterior vitrectomy) for the 3 groups.Conclusions
During the learning curve, the intraoperative outcomes and safety of FLACS are comparable to the conventional phacoemulsification technique. After the learning curve, FLACS is significantly superior to conventional surgery in all measured phacoemulsification parameters. 相似文献13.
Pritam Bawankar Preetam Samant Tatyarao Lahane Ragini Parekh Sayalee Lahane 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(2):275-279
Objective
To study the relationship between mean platelet volume (MPV) and central retinal vein occlusion (CRVO) in hypertensive patients.Design
Hospital-based, retrospective, case control design.Participants
The sample group consisted of 100 patients with a known history of hypertension and who are diagnosed with CRVO. The control group consisted of 100 age and sex-matched patients with the sample group and who had a sole history of hypertension without any other systemic diseases and the best corrected visual acuity of 20/20 in both the eyes.Methods
CRVO was diagnosed based on clinical examination. All cases and control subjects underwent complete ocular examination. MPV, platelet count, hemoglobin, white blood cell count and hematocrit parameters were recorded for both groups. The data of patients with CRVO was compared with the control subjects. Confidence interval was set at 95% with a P-value of < 0.05.Results
MPV was significantly higher among hypertensive cases diagnosed with CRVO when compared with the hypertensive control group (8.059 ± 0.016, 7.442 ± 0.15 fL respectively; P < 0.001). The platelet count was lower in the control group, but the difference was not significant. The systolic blood pressure was significantly higher in the sample group.Conclusions
Our results demonstrated that MPV values were significantly higher in patients with CRVO, suggesting that increased MPV may contribute to the development of CRVO. 相似文献14.
Belal Azab Raghda Barham Dema Ali Zain Dardas Lana Rashdan Maysa Bijawi Ranad Maswadi Abdelhalim Awidi Hanan Jafar Mohammed Abu-Ameerh Muawyah Al-Bdour Sami Amr Abdalla Awidi 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):51-59
Objective
To identify the disease-causing variants in 2 families with autosomal recessive inherited retinal dystrophies (IRDs) and to characterize phenotypic variability across the affected family members.Design
Exome sequencing and ophthalmic clinical examination study.Participants
Six members from 2 consanguineous Jordanian families with IRD.Methods
Ophthalmic examinations and whole-exome sequencing (WES) were performed to identify IRD-causing variants in affected individuals from each family, followed by segregation analysis of candidate variants in affected and unaffected family members by Sanger sequencing.Results
We identified 2 different homozygous deletion variants in CERKL in each family: a novel pathogenic variant, c.450_451delAT, and a known variant, c.1187_1188delTG. Both variants co-segregated with the disease in all affected family members. The resulting phenotypes further supported that CERKL is associated with cone–rod dystrophy (CRD) rather than retinitis pigmentosa (RP), as originally established.Conclusion
Our study expands the genotypic spectra of CERKL variants, providing insights into the relevant pathogenesis of RP/CRD. We also confirm that the WES approach is a valuable tool for the molecular diagnosis of retinopathies. 相似文献15.
Jin-Woo Kwon Jung Min Bae Jung-Sub Kim Donghyun Jee Jin A. Choi 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(2):237-241
Objective
We hypothesized that the ocular dominance associated with brain asymmetry would influence macular structure. We assessed the structural asymmetry of the macula by ocular dominance.Methods
A total of 144 patients with no ophthalmic abnormalities were examined. After classifying eyes as dominant or non-dominant using the hole-in-a-card test, the macular ganglion cell inner plexiform layer and the macular thickness were measured in both groups using spectral domain optical coherence tomography, and we sought associations between ocular dominance and retinal thickness.Results
Ocular dominance was more frequently found in right eyes than in left eyes (68.75% vs 31.25%, respectively; p < 0.001). Using conditioned logistic regression, the right eye and the temporal-to-nasal retinal thickness ratio of the macular ganglion cell inner plexiform layer were selected as a final model for the determination of ocular dominance (p < 0.001, p = 0.013 respectively).Conclusions
Macular vertical asymmetry was associated with ocular dominance. The macular structure and ocular dominance associated with visual cortex lateralization have functional and structural relationships. 相似文献16.
Albert Y. Cheung Bradley J. Anderson David G. Heidemann Chirag Gupta 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):125-129
Objective
To analyze 12 cases of late-onset diffuse lamellar keratitis (DLK) following uncomplicated LASIK and propose a method of management.Design
Retrospective observational case series, literature review.Participants
Patients who developed late-onset DLK following LASIK.Methods
Retrospective chart review of all patients with late-onset DLK from January 2014 to August 2015. Data collected included demographic information, probable cause of DLK, stage of DLK, baseline examination, treatment, clinical course, outcomes, complications, and last follow-up examination. Review of relevant literature included searching for all prior cases and case series relating to “diffuse lamellar keratitis,” “late-onset DLK,” “Secondary Sands,” and “delayed-onset DLK” by searching PubMed with these search terms.Results
Twelve eyes of 11 patients presented with late-onset DLK following LASIK. Onset ranged from 8 months to 17 years following LASIK. Stage of DLK ranged from stage I to III, and all patients responded well to aggressive corticosteroids without lifting of the LASIK flap. Final visual acuity for stage I/II and III eyes did not demonstrate a significant difference (p = 0.218). DLK resolved by a mean of 4.86 weeks for all eyes.Conclusion
Late-onset DLK can present at any time following LASIK with a wide range of inciting factors causing a nonspecific (and likely immune-related) inflammatory reaction. Based on our findings, aggressive oral and topical corticosteroids should be tried before lifting the LASIK flap as long as infection is not suspected or inciting debris is not seen in the flap because the vast majority resolve with such therapy. 相似文献17.
Larry Ha Alex Wright Dannen D. Wright Ashlie Bernhisel William R. Barlow Jeff H. Pettey Brian Zaugg Randall J. Olson 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):136-138
Objective
To compare relative efficiency and chatter of high aspiration and vacuum settings.Design
In vitro laboratory study.Methods
The John A. Moran Eye Center Laboratories, University of Utah, Salt Lake City, Utah, was the study setting. Porcine nuclei were fixed in formalin and cut into 2.0 mm cubes. Lens cubes were phacoemulsified with Balanced tips at 50 and 60 mL/min aspiration with 500, 600, and 700 mm Hg vacuum with monitored forced infusion. Experiments were conducted at constant torsional power, longitudinal power, and intraocular pressure.Results
No significant change was observed in average chatter across each tested setting. Increasing aspiration rate did not increase efficiency. Increasing vacuum up to 600 mm Hg from 500 mm Hg did not change efficiency. However, increasing vacuum to 700 mm Hg decreased efficiency (p = 0.008 for 500 mm Hg vs 700 mm Hg and p = 0.05 for 600 mm Hg vs 700 mm Hg). Increasing aspiration and increasing vacuum did not significantly improve chatter.Conclusions
Increasing aspiration above 50 mL/min did not improve phacoemulsification efficiency. Increasing vacuum settings to 700 mm Hg decreases efficiency. Chatter did not significantly change with increasing aspiration and vacuum settings. 相似文献18.
Kelsey A. Roelofs Helya Aghazadeh Marvi Cheema Ezekiel Weis Jaime Badilla 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(1):106-110
Objective
To report indications for eye removal, histopathological diagnosis, and surgical trends in enucleation versus evisceration over a 23-year period.Design
Retrospective consecutive case series.Participants
All patients undergoing enucleation or evisceration at the Royal Alexandra Hospital in Edmonton, Canada, between January 1994 and December 2016.Methods
Demographic information was recorded and archived hospital charts were accessed and reviewed for clinical diagnosis, histopathological diagnosis, and the type of implant used. Univariate and multivariable logistic regression analysis was performed. The study cohort was divided into 2 time periods by separating the first 10 years of the study period (1994–2004 inclusive) from the rest of the study time period (2005–2016 inclusive).Results
A total of 786 patients with a mean age (±?SD) of 52 ±?23 years were included. The most common clinical diagnosis was blind painful eye (56%) followed by intraocular tumour (23%). Corresponding pathological examination of specimens revealed chronic inflammatory change (46%) and intraocular tumour (25%). Eyes with active infection were more likely to be eviscerated (odds ratio: 4.67; p?<?0.001) when compared to other diagnostic groups, and all eyes diagnosed with intraocular tumours were enucleated. While most eyes in the study were enucleated, the proportion of eyes eviscerated increased over the study period (p?=?0.010) from 8% between 1994–2004 to 14% between 2005–2016.Conclusions
While enucleation was performed more commonly overall, the incidence of evisceration increased throughout the study period. There were no instances of occult intraocular tumour in patients who were eviscerated. 相似文献19.
Serdar Aktaş Fatih Temiztürk 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(2):176-179
Objective
To evaluate the effects of Behçet’s syndrome (BS) on tear osmolarity and tear film function tests.Methods
Thirty patients with BS and 41 control subjects were enrolled in this study. Tear osmolarity was measured with an osmometer. Tear film function tests involved corneal fluorescein staining, tear film breakup time (TBUT), Schirmer’s 1 test, and an Ocular Surface Disease Index (OSDI) Questionnaire.Results
The patients with BS had significantly higher tear osmolarity (p = 0.000) and OSDI scores (p = 0.000) than the healthy controls. The TBUT (p = 0.000) and Schirmer’s 1 test (p = 0.033) results were significantly lower in the BS group, but the fluorescein staining results were not statistically different. A significant correlation was found between tear osmolarity, OSDI, and the activity of BS.Conclusions
BS is associated with hyperosmolarity of the tear film, which can damage the ocular surface and affect tear functions. 相似文献20.
Kiersten Schock Alex Ragan John T. Huang 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(2):171-175