口腔平滑肌瘤——一例报告及文献复习

平滑肌瘤少见于口腔,常见于肠胃道和子宫,子宫内平滑肌瘤有20％的病人是30岁以上。软组织的平滑肌瘤主要发生在皮肤和皮下组织。复习文献有57例,继后Ekestrom报告8例发生于颊和外耳,Robinson等报告16例口腔平滑肌肉瘤,加上作者报告一例平滑肌瘤。所有作者报告的病例,口腔内最常见部位是舌,大多数舌平滑肌瘤是无蒂的包块,但Merrill等报告一例有蒂。其次依次常见部位是颊部、硬腭,下唇,其他部位为上唇、     

下颌平滑肌肉瘤一例报告

平滑肌肿瘤见于人体具有平滑肌的部位(胃肠道、子宫等)。文献报道,平滑肌肉瘤约占非造血间叶组织肉瘤的4%。发生于口腔的平滑肌肉瘤则极为罕见。直至1978年,国外仅报道了35例口腔平滑肌瘤和11例口腔平滑肌肉瘤。国内迄今报告了口腔平滑肌瘤共30     

口腔血管平滑肌瘤

平滑肌瘤可发生在人体任何部位的平滑肌。子宫是最常好发的部位,20%的病例发生在30岁以上妇女的子宫。其他部位为清化道壁、皮肤和皮下组织。1884年Blanc首先报告了一例口腔平滑肌瘤,男性,33岁。发生在口腔的平滑肌瘤极为罕见,复习文献仅68例。复习文献可知口腔内最常见部位是舌、腭和颊,其次是唇部。其他部位为下颌颊沟、牙龈、口底、下唇沟、涎腺、悬雍垂、下颌中央和上颌牙槽。患者的年龄从幼年至85岁间,平均年龄46岁。最好发于40～59岁组。性别比为1:1,男性稍偏高。平滑肌瘤     

口腔血管肌瘤的超微结构

此瘤虽然常见于尿道,肠胃道,皮肤和皮下组织,然而发生于口腔的平滑肌瘤却是罕见的(Dunig and Ayer 1959)。口腔平滑肌瘤新近已由Cherrck等人(1973)和Gut-mann等人(1974)重新予以评定。在其评定中Galili和Shteyer(1974)曾记录了1884年以的来文献中32例血管平滑肌瘤(血管肌瘤,     

舌根部平滑肌瘤1例报告

平滑肌瘤系来源于平滑肌组织的良性肿瘤,最多见于子宫,其次为胃肠道.发生在口腔舌根部的平滑肌瘤较罕见,我科曾收治1例,报道如下.     

舌软骨瘤2例

软骨瘤常发生于四肢的管状骨,发生于软组织的软骨瘤是罕见的病变,发生于口腔的软骨瘤更加少见。除在腭板或牙槽嵴外,发生于口腔骨外软骨瘤的报道不到30例,并且最常见的发生部位为舌黏膜。我院近期诊治了2例舌软骨瘤的患者,现报道如下：     

舌背前部甲状舌管囊肿1例报告

舌背前部甲状舌管囊肿１例报告甲状舌管囊肿可发生于颈正中线自舌盲孔至胸骨切迹任何部位,临床上以舌骨上、下部为最常见,而发生于舌背前部者很罕见。我科收治１例报告如下。患儿刘××,男,５岁。住院号６２９４２。患儿出生约１个月,父母无意发现其舌背部有一黄豆粒...     

应用PCR技术研究口腔乳头状瘤与病毒感染

应用ＰＣＲ技术研究口腔乳头状瘤与病毒感染杨淑华高文涛欧阳喈白求恩医科大学口腔医学院口腔鳞状细胞乳头状瘤是一种良性肿瘤，主要发生于３０～５０岁患者，此瘤常累及软腭、舌腹、舌侧缘及下唇。由于其具有向鳞状细胞癌转化的潜能，口腔乳头状瘤已被视为一种癌前病变。...     

舌黏膜结核性溃疡1例报告

回顾分析1例发生于左舌的结核性溃疡病例,并结合相关文献进行讨论.通过对该患者行组织活检,确诊为舌部溃疡,并给予抗结核治疗,无复发.发生于口腔内的结核性溃疡非常少见,应给予足够重视,临床应尽早行病理学检查,确诊后及时给予抗结核治疗.     

口腔颌面部脂肪瘤

脂肪瘤是一种可发生于全身各部位脂肪组织内的良性肿瘤,约占全身良性肿瘤的4％～5％。最常见于皮下脂肪组织内。发生于口腔内者很少,仅占口腔内良性肿瘤的1％～4％,国外文献报告病例数量最多仅42     

Leiomyoma of tongue: a case report

Oral leiomyoma is a benign smooth muscle tumor. Leiomyoma occurs most frequently in the uterine myometrium, gastrointestinal tract, and skin. Occurrence in the oral cavity is considered rare, probably because of the paucity of smooth muscle tissue at this area. Smooth muscle tumors can occur at any age and usually appear as a slow growing, firm submucosal nodule. Most lesions are asymptomatic, although occasional tumors can be painful. The most common sites are lips, palate and tongue. The diagnosis of leiomyoma in the oral cavity is mainly determined by histological studies. The purpose of this article is to present a case of a 48 year-old woman with a leiomyoma of tongue.     

Leiomyoma of the tongue: report of case.

An instance of leiomyoma of the tongue has been reported. The theories of origin of smooth muscle tumors within the oral cavity have been reviewed. The necessity for differentiation of leiomyomas from other spindle-cell tumors and the need for thorough examination of the specimen have been discussed. Complete surgical excision of these tumors is the preferred treatment.     

Oral leiomyoma

Benign tumors of smooth muscle origin are rare in the oral cavity. This paper reviews 67 cases from the literature and six previously unpublished cases of oral leiomyoma. Tongue, hard palate and buccal mucosa are the most common sites of this lesion and the vascular leiomyoma or angiomyoma is the predominant histologic type.     

Leiomyoma of oral cavity: case report and literature review

Leiomyoma is a benign smooth muscle tumour, that occurs most frequently in the uterine myometrium, gastrointestinal tract, skin and lower extremities of middle-aged women. Leiomyomas are uncommon in the oral cavity, but in this location are usually localized on the tongue, lips and palate. Most lesions are asymptomatic, although occasional tumours can be painful. The diagnosis is mainly determined by histological studies due to its unspecific clinical appearance.The purpose of this article is to present a case report of 49-year-old male patient with a lesion of the lower lip. After surgical resection hematoxylin-eosin staining confirmed the diagnosis of leiomyoma.     

Granular cell leiomyoma of the oral cavity

Granular cytoplasmic change is a reported but uncommon finding in leiomyoma. Leiomyoma in the oral cavity is also uncommon, and granular cell change in oral leiomyomas, to the best of our knowledge, has not been previously reported in the English literature. Two cases of oral leiomyomas with significant granular cell change are presented. These tumors may be confused with the more common granular cell tumor, however, routine histology and immunohistochemistry aided in establishing the diagnosis. Ultrastructural studies were done for one case. Both tumors were immunoreactive for muscle markers, namely, smooth muscle actin and desmin. One of the tumors (case 2) reacted postiviely for HHF-35 and alpha-1 antitrypsin. The tumors were unreactive for S-100 protein, pancytokeratin, myoglobin, and factor VIII related antigen (case 2).     

Vascular leiomyoma of the oral cavity

Leiomyomas may occur in the humam body wherever smooth muscle is present. The uterus is the most common site; 20% of reported cases occur in uteri of women over the age of 30 years.¹ Other sites are the wall of the alimentary tract, the skin, and the subcutaneous tissue.² The earliest case of leiomyoma of the oral cavity was reported by Blan³ in 1884 in a 33-year-old man. The leiomyoma is considered a rare tumor of the oral cavity; our review of the literature has disclosed only 68 reported cases.     

Vascular leiomyoma of the oral cavity. Clinical, histopathological and immunohistochemical characteristics. Presentation of five cases and review of the literature

Leiomyoma, a benign neoplasia arising from smooth muscle is an uncommon neoplasia of the oral cavity. The most common histological subtype in the oral cavity is the vascular one. To supplement information on vascular leiomyoma of the oral cavity (VLOC), we present cases of VLOC describing their clinical, histological, and immunohistochemical characteristics. Case reports. Five cases of VLOC (3 females; 2 males) from the Clinical and Experimental Pathology Laboratory, Dental School, National Autonomous University of México, are included. The most frequent clinical characteristic of VLOC was a single, asymptomatic, slow growing nodule. The age average of the cases was 40.6, however 3 out of our 5 cases were < or = 40 years old at the moment of their diagnosis. The lesions were composed of fusiform cells arranged in bundles or fascicles. The neoplastic cells were characterized by eosinophilic cytoplasm and tapered nuclei. The presence of vascular spaces was prominent in all cases. The immunocharacteristics of VLOC neoplastic cells were: alpha smooth muscle (+); vimentin (+), desmin (+), CD34 (-) and S-100 protein (-). The endothelial cells of vascular spaces were CD34 (+). Differential diagnosis of VLOC with fusocellular neoplasm is discussed.     

Synchronous oral leiomyosarcoma and squamous cell carcinoma

An unusual case of synchronous squamous cell carcinoma and leiomyosarcoma of the oral cavity is reported in a patient without any identified environmental risk or predisposing factors. The invasive squamous cell carcinoma involved the tongue, whereas the leiomyosarcoma was located in the soft palate. No immunostaining was found for human papillomavirus or Epstein-Barr virus, and in situ hybridization showed negativity for human papillomavirus DNA within the tumor cells. Alterations of bcl -2, c-erb -b2 and Rb oncoproteins were not found immunohistochemically. Overexpression of p53 was detected by immunohistochemistry in both tumors, but p53 gene mutations were not found by polymerase chain reaction. Neither loss of heterozygosity of p53 nor microsatellite instability was detected in this patient. The smooth muscle nature of the leiomyosarcoma was confirmed by immunohistochemical methods. To our knowledge, synchronous smooth muscle and epithelial oral tumors have not previously been reported.     

Oral leiomyoma: case report

Leiomyoma of the oral cavity is infrequently found because of the scarcity of smooth muscle in the mouth. A review of the literature yielded only 124 cases reported from 1884 to 1987. A new case of primary leiomyoma of the lower buccal sulcus is presented. Although the recurrence rate has been very low, wide surgical excision is recommended because of the high incidence of malignancy of this tumor in the oral cavity contrasted with other parts of the body.     

Leiomyoma of the hard palate: a case report

Leiomyoma is a benign smooth muscle tumor that is very rarely located in the oral cavity. It is accepted that the smooth muscle giving rise to this tumor corresponds to the tunica media of the arteries. The tumor can develop at any age, with no clear gender predilection, and typically manifests as a slow-growing, asymptomatic lesion. The diagnosis is based on the histopathological study, with the use of specific staining techniques, including immunohistochemical markers. Treatment consists of complete resection of the lesion, with due safety margins. We present the case of a 57-year-old male with a tumor located for the previous four months in the region of the hard palate, adjacent to the left upper premolars. After surgical resection with safety margins, hematoxylin-eosin staining and immunohistochemical study confirmed the diagnosis of leiomyoma.