“一站式”双介入技术在凶险型前置胎盘并胎盘植入剖宫产中的应用

目的:分析球囊导管临时封堵双侧髂内动脉+选择性血管栓塞术"一站式"应用于凶险型前置胎盘并胎盘植入剖宫产术的疗效。方法:2016年5月—2017年11月我院应用复合手术室治疗凶险型前置胎盘并胎盘植入患者23例;所有患者于剖宫产术前行双侧髂内动脉球囊置入,待胎儿娩出脐带结扎后充盈球囊,剖宫产术后取出球囊导管并行子宫供血动脉栓塞术。记录剖宫产术中出血量、术后24 h出血量、球囊置入过程X线曝光时间及照射剂量、子宫切除情况、术后住院时间及并发症情况。结果:23例均成功置入双侧髂内动脉球囊(球囊规格为8 mm×40 mm 5例,10 mm×40 mm 11例,12 mm×40 mm 7例);胎盘娩出后撤出球囊导管,产科医生按压宫底,均发现不同程度的活动性出血,遂行子宫供血动脉栓塞术,其中,22例子宫供血动脉均源自髂内动脉;1例同时合并髂外动脉供血,活动性出血经栓塞治疗后均好转;1例因胎盘植入子宫下段肌层至浆膜层,并部分植入膀胱,行全子宫切除及膀胱部分切除修补术;球囊置入X线曝光时间平均为(88.7±16.8)s,球囊置入过程接收放射线剂量平均为(18.2±4.5)mGy;术中出血量平均为1000 ml(500~3 000 m1);术后24 h出血量580 ml(70~1 200 m1),术后平均住院时间7 d(4~10 d);产出23名新生儿,1分钟Apgar评分:10分19名,9分2名,8分、7分各1名;5分钟Apgar评分均10分;随访期间未发现术中及术后的严重相关并发症。结论:"一站式"双介入技术可有效降低剖宫产术中及产后出血量,有效降低子宫切除的风险;复合手术室为凶险型前置胎盘并胎盘植入提供了理想的治疗平台。     

髂内动脉球囊临时置入在五例凶险性前置胎盘剖宫产中的应用

目的 探讨髂内动脉球囊临时置入在凶险性前置胎盘剖宫产中的临床应用.方法 5例均经超声和磁共振诊断为凶险性前置胎盘伴胎盘植入患者,在剖宫产术前行髂内动脉球囊临时置入,待胎儿娩出脐带结扎后充盈球囊,剖宫产术后24 h去除球囊,记录所受射线剂量、出血量,并观察有无并发症发生.结果 5例髂内动脉球囊临时置入,均获得成功.出血量＜ 500 ml者3例,＞1000ml者2例.3例保留子宫,2例因难治性出血,行子宫全切1例,子宫次全切1例.以上5例均未发生球囊置入并发症.结论 髂内动脉球囊临时置入可减少凶险性前置胎盘剖宫产出血量,并降低了子宫切除风险.     

临时球囊置入髂总动脉在凶险性前置胎盘伴胎盘植入中的应用

目的：探讨临时性球囊置入髂总动脉在凶险性前置胎盘伴胎盘植入剖宫产术中的临床应用。方法回顾分析5例经超声或 MR 检查诊断为凶险性前置胎盘合并胎盘植入患者,其中1例为 Rh(-)血型患者。剖宫产术前预置临时球囊于双侧髂总动脉,数字减影血管造影(DSA)明确球囊导管位置后,固定导管送产科手术室,术中待胎儿娩出后迅速充盈球囊,剖宫产术后6~8 h拔除球囊导管。观察并记录失血量、输血量、子宫切除率、接受 X 射线照射时间及剂量。结果5例临时性球囊置入髂总动脉均获得成功。出血量<500 mL 者1例,500~1000 mL 者4例。1例因胎盘组织植入过深达浆膜层,穿透性胎盘,短时间内出血较为凶猛,行子宫次全切除术。其余4例保留子宫。结论剖宫产术前髂总动脉置入临时球囊能够减少剖宫产术中失血量、输血量,且能降低因术中不可控制的出血而继发子宫切除的风险。     

腹主动脉预置球囊辅助前置胎盘伴胎盘植入剖宫产临床应用

目的 探讨腹主动脉预置球囊辅助前置胎盘伴胎盘植入剖宫产的临床应用价值.方法 对72例前置胎盘伴胎盘植入产妇腹主动脉预置球囊辅助剖宫产,其中33例为凶险性前置胎盘(A型),36例为瘢痕子宫、前置胎盘伴胎盘植入(B型),3例为无剖宫产史前置胎盘伴胎盘植入(C型).记录剖宫产术中出血量、子宫切除情况、球囊预置术中X线辐射量及介入操作相关并发症.结果 剖宫产术中A型、B型、C型产妇平均出血量分别为1 461 ml、947 ml、533 ml;9例子宫大部切除,32例子宫修补;2015年17例、2016年55例球囊预置术中平均X线辐射量分别为(28.5±14.1) mGy、(3.7±2.5) mGy;住院期间发生右股浅动脉血栓1例,右下肢静脉血栓1例,皮下血肿2例.结论 腹主动脉球囊预置辅助前置胎盘伴胎盘植入产妇剖宫产,可有效减少术中出血量,明显降低子宫切除率;手术操作简便,X线辐射时间短;熟练操作,能进一步减少介入操作相关并发症.     

球囊临时阻断技术在凶险性前置胎盘剖宫产术中的应用

目的 比较不同球囊阻断技术用于凶险性前置胎盘剖宫产术中的安全性、有效性.方法 回顾性分析2014年3月至2016年4月施行剖宫产术的15例凶险性前置胎盘患者.为减少术中出血并尽可能保留子宫,其中7例接受腹主动脉球囊临时阻断术(A组),8例接受双侧髂内动脉球囊临时阻断术(B组).记录并比较两组患者介入术中辐射剂量,剖宫产术中出血量、输血量、子宫切除率,术后住院时间及介入相关并发症.结果 15例患者均为中央型前置胎盘伴胎盘植入广泛,在球囊临时阻断辅助下均顺利实施剖宫产手术.7例(A组4例,B组3例)作子宫次全切,两组各1例术后出现下肢动脉血栓栓塞.A组辐射剂量明显低于B组(P＜0.01),术中出血量、输血量、子宫切除率、产后住院时间及介入相关并发症发生率均低于B组,但病例数有限,差异无统计学意义(P＞0.05).结论 球囊阻断技术辅助剖宫产术是治疗凶险性前置胎盘的安全有效方法,腹主动脉球囊临时阻断术辐射剂量明显低于双侧髂内动脉球囊临时阻断术.     

球囊封堵术在产科大出血的临床应用

目的 探讨球囊封堵术治疗凶险性前置胎盘的临床疗效.方法 2015年1月至2016年3月采用球囊封堵术协助产科处理凶险性前置胎盘产妇16例.15例经彩色超声或MRI诊断为中央型前置胎盘并高度怀疑胎盘植入,择期于剖宫产前双侧髂内动脉预置球囊,胎儿取出同时立即充盈双侧球囊对目标血管作临时封堵,根据产科医师止血状况适时撤出球囊;1例行急症腹主动脉临时球囊封堵术,开腹发现胎盘穿透至前壁浆膜下,予子宫切除术.结果 16例球囊封堵术均获成功,平均阻断时间15 min,出血量300～1200 ml.结论 剖宫产手术前球囊封堵术治疗凶险性前置胎盘安全可靠,可显著减少术中出血、迅速有效止血、为剖宫产提供清晰术野及挽救产妇生命,充分体现产科、介入科等多学科协作的必要性.     

超声导引球囊阻断术在13例凶险性前置胎盘剖宫产中的应用

目的 探讨超声导引球囊阻断术在凶险性前置胎盘产妇行剖宫产手术中的应用价值.方法 曲靖市第一人民医院介入科联合超声科,协助产科完成凶险性前置胎盘剖宫产手术共13例,13例产妇均经彩色超声和MRI诊断为中央型前置胎盘.剖宫产术前于双侧髂总动脉或腹主动脉预置封堵球囊,胎儿娩出同时立即充盈球囊对目标血管进行临时封堵,并根据产科医师止血状况,适时撤出球囊.结果 13例中1例为腹主动脉封堵,12例为双侧髂总动脉封堵.13例中12例经超声导引封堵成功,平均阻断时间＜15 min,术中出血量800～1 500 ml.结论 剖宫产前超声导引球囊阻断术治疗凶险性前置胎盘安全可靠,可明显减少术中出血,无X线辐射,值得临床推广.     

双侧髂内动脉、髂总动脉球囊阻断术辅助凶险性前置胎盘剖宫产临床效果对比

【摘要】 目的 比较双侧髂内动脉球囊阻断术和双侧髂总动脉球囊阻断术在凶险性前置胎盘剖宫产术中应用的临床效果。方法 回顾性分析2017年9月至2019年2月于徐州医科大学附属医院住院剖宫产分娩的64例凶险性前置胎盘产妇的临床资料。根据剖宫产术前介入术式不同,分为双侧髂内动脉球囊临时阻断术组（A组,n=45）和双侧髂总动脉球临时囊阻断术组（B组,n=19）。观察记录和比较两组剖宫产手术时间、透视时间、术中出血量和输血量、子宫切除率、术后住院时间、新生儿Apgar评分及手术相关并发症。结果 两组介入手术均获得成功。A组、B组平均透视时间分别为（194.58±77.41） s、（77.62±51.51） s,术中出血量分别为（1 522.22±831.18） mL、（1 042.11±478.79） mL,术中输血量分别为（986.67±739.04） mL、（715.79±433.67） mL,差异均有统计学意义（P＜0.05）;两组剖宫产手术时间、新生儿Apgar评分、术后住院时间、子宫切除率差异均无统计学意义（P＞0.05）。 结论 两种介入球囊阻断术均可有效减少凶险性前置胎盘产妇剖宫产术中出血量,双侧髂总动脉球囊阻断术操作更简单,且剖宫产术中透视时间和出血量更少,临床应用中更具有优势。     

球囊阻断腹主动脉控制凶险性前置胎盘并胎盘植入剖宫产术中出血22例

目的 应用球囊导管阻断腹主动脉后再行胎盘的剥离,探讨其对减少凶险性前置胎盘并胎盘植入的剖宫产术中出血的临床意义.方法 回顾性分析22例凶险性前置胎盘并胎盘植入的剖宫产患者.所有患者均接受术前放置球囊导管,凶险性前置胎盘剖宫产术中先娩出胎儿,断脐后立即给予球囊阻断.结果 所有患者均证实为凶险性前置胎盘并胎盘植入,包括3例穿透性胎盘植入患者.该方法的技术成功率为86.3％(19/22).19例患者成功接受手术并保留子宫.子宫切除率约13.7％(3/22).术中出血量为(686±355)ml.22例患者中仅3例穿透性胎盘植入的患者术中输血,其余19例患者均未输血,术中球囊阻断时间以及胎儿的辐射剂量分别为(25.4±7.2) min和(30.2±8.9) mGy.术后和随访期间并无介入相关的并发症.结论 腹主动脉球囊阻断术能够有效控制凶险性前置胎盘并胎盘植入患者胎盘剥离时引起的术中大出血,降低输血需求及子宫切除率.     

应用复合手术室治疗凶险性前置胎盘并胎盘植入的临床分析

目的探讨应用复合手术室在凶险性前置胎盘并胎盘植入的治疗经验。方法回顾性分析应用复合手术室治疗30例凶险性前置胎盘并胎盘植入的产妇病例资料,手术方案采用"一站式"腹主动脉球囊阻断辅助剖宫产术。记录术中出血量、输血量、子宫切除例数、球囊阻断时间、孕妇接受射线剂量及相关并发症等。结果 30例患者成功接受手术,29例术前置入球囊,1例行子宫切除术。18例出血量在500ml以内,500～1 000ml 5例,1 000～1 500ml 3例,2 000ml左右的2例,1例患者出血量约5 000ml,平均出血量(843±934)ml。仅对术中出血大于2 000ml的4例产妇给与输血,平均输注红细胞(2100±1321)ml。球囊阻断时间以及胎儿的平均辐射剂量分别为(20.4±5.2)min,(18.2±5.9)mGy。无产妇及胎儿死亡,无介入相关的严重并发症发生。结论应用复合手术室治疗凶险性前置胎盘并胎盘植入安全有效,能显著降低术中出血量及子宫切除率,是今后发展的方向。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.     

Bronchial stump fistula :treatment with covered retrievable hinged metallic stents-preliminary clinical experience

Objective To evaluate the preliminaily clinical efficacy and retrievability of a retrievable hinged covered metallic stent in the treatment of the bronchial stump fistula （BSF）. Methods Between April 2003 and March 2005, 8 patients with bronchial stump fistula after pneumonectomy or lobectomy were treated with two types （A and B） of retrievable hinged covered metallic stents. Type A stent was placed in 6 patients and type B in 2 under fluoroscopic guidance. The stent was removed with a retrieval set when BSF was healed or complications occurred. Results Stent placement in the bronchial tree was technically successful in all patients, without procedure-related complications. Immediate closure of the BSF was achieved in all patients after the procedure. Stents were removed from all patients but one. Removal of the stents was difficult in two patients due to tissue hyperplasia. Patients were followed up for 6 - 21 months. Placement of the stents remained stable in all patients except one due to severe cough. Permanent closure of BSF was achieved in 7 （87.5%） of 8 patients. Conclusion Use of a retrievable hinged covered expandable metallic stent is a simple, safe, and effective procedure for closure of the BSF. Retrieval of the stent seems to be feasible. （J Intervent Radiol, 2007, 16： 253-257）     

Prevalence and severity of hip and groin pain in sub‐elite male football: a cross‐sectional cohort study of 695 players

The purpose of this study was twofold: (a) to investigate the prevalence of hip and groin pain in sub‐elite male adult football in Denmark and (b) to explore the association between prevalence and duration of hip and groin pain in the previous season with the Copenhagen Hip and Groin Outcome Score (HAGOS) in the beginning of the new season. In total 695 respondents from 40 teams (Division 1–4) were included. Players completed in the beginning of the new season (July–Sept 2011) a self‐reported paper questionnaire on hip and/or groin pain during the previous season and HAGOS. In total 49% (95% CI: 45–52%) reported hip and/or groin pain during the previous season. Of these, 31% (95% CI: 26–36%) reported pain for >6 weeks. Players with the longest duration of pain during the previous season had the lowest HAGOS scores, when assessed at the beginning of the new season, P < 0.001. This study documents that half of sub‐elite male adult football players report pain in the hip and/or groin during a football season. The football players with the longest duration of pain in previous season displayed the lowest HAGOS scores in the beginning of the new season.