伴有肠梗阻的结直肠癌腹腔镜辅助手术

目的探讨对伴有肠梗阻的结直肠癌患者在腹腔镜辅助下行结直肠癌根治切除术同时一期吻合的可行性。方法对6例伴肠梗阻的结直肠癌患者行腹腔镜辅助下结直肠癌根治切除一期吻合手术。结果手术均获得成功。5例伴不全肠梗阻患者行腹腔镜辅助结直肠癌切除一期吻合术:1例伴完全肠梗阻患者行手辅助腹腔镜乙状结肠癌切除一期吻合术。无中转开腹和并发症发生。手术时间平均200(150-240)min,出血量平均60(20～100) ml。术后住院时间8-11 d。术后随访8-28个月,未见癌肿复发转移。结论对于伴肠梗阻的结直肠癌患者行腹腔镜辅助下肿瘤根治术一期吻合是可行的。     

腹腔镜肝切除术治疗左肝内胆管结石的临床应用

目的 探讨腹腔镜肝切除术治疗左肝内胆管结石的技术与疗效。 方法 回顾性分析2011年1月至2016年12月完成67例腹腔镜肝切除术治疗左肝内胆管结石临床及随访资料。 结果 全部67例患者合并左半肝或左外叶肝萎缩,腔镜手术方式包括左外叶肝切除48例、左半肝切除19例。其他腹腔镜下联合术式包括：胆囊切除术52例、胆总管探查术43例、T管引流术39例,胆总管一期修补术4例。手术切口长度（4.67±1.26）cm。术后发生胆漏3例,均经引流观察后自愈;1例因术后腹腔大出血合并胆瘘再手术治愈;肝脓肿1例,膈下脓肿1例,均经穿刺引流治愈。 结论 腹腔镜肝切除术治疗左肝内胆管结石安全可靠,术中应尽量取净其他胆道残余结石并连续紧密缝合左肝管残端。如结石已被取净胆总管的探查和T管引流并非必需。     

经皮经肝选择性门静脉栓塞化疗在结肠癌多发肝转移分期手术中的应用

门静脉栓塞(portal vein embolization,PVE)用于结直肠癌多发肝转移二期肝切除术效果良好[1].我们对1例乙状结肠癌并左、右肝多发转移癌的患者一期行原发肿瘤根治性切除+肝左外叶切除,术后行经皮选择性右肝门静脉栓塞化疗(portal vein chemoembolization,PVCE),二期行右半肝切除术,术后患者已无瘤生存18个月,报告如下.     

腹腔镜肝切除治疗58例肝内胆管细胞癌的临床探讨

目的探讨腹腔镜肝切除治疗肝内胆管细胞癌(ICC)的安全性及可行性。方法采用回顾性研究方法。收集2016年1月—2018年12月湖南师范大学附属第一医院行腹腔镜肝切除治疗的58例ICC患者的临床资料。其中男性34例,女性24例;年龄34~71岁,中位年龄54岁。观察指标:(1)手术治疗情况:手术方式、手术时间、术中出血量、术中输血率、术中肝门阻断时间、中转率、术后并发症、术后住院时间、术后胃肠道恢复时间、围手术期有无死亡病例及非计划手术病例。(2)术后病理情况。(3)随访。采用门诊和电话方式进行随访,了解患者术后生存情况。随访时间截至2019年6月。正态分布的计量资料以均数±标准差(Mean±SD)表示,计数资料用频数和百分比(%)表示。结果本研究共纳入58例患者,其中48例患者在腹腔镜下完成ICC根治性外科切除手术,10例患者行腹腔镜中转开腹。(1)手术治疗情况:手术方式有腹腔镜下左半肝(Ⅱ、Ⅲ、Ⅳ段)切除,腹腔镜下右半肝(Ⅴ、Ⅵ、Ⅶ、Ⅷ段)切除,腹腔镜下右肝后叶(Ⅵ、Ⅶ段)切除,腹腔镜下扩大右后叶切除,腹腔镜下肝中叶(Ⅳ、Ⅴ、Ⅷ段)切除,腹腔镜下Ⅴ、Ⅵ段切除,腹腔镜下左半肝(Ⅱ、Ⅲ、Ⅳ段)联合肝尾叶(Ⅰ、Ⅸ段)切除,腹腔镜扩大左半肝切除,腹腔镜下Ⅵ段切除,腹腔镜下Ⅶ、Ⅷ段切除,腹腔镜左肝外叶(Ⅱ、Ⅲ段)切除,腹腔镜右肝肿块切除;手术时间(320.38±107.68)min;术中出血量(262.34±76.06)mL;术中输血率为0(0/58);术中肝门阻断时间(48±15)min;其中10例腹腔镜中转开腹手术,中转率17.2%(10/58);术后胆瘘发生率为6.9%(4/58),保守治疗、通畅引流(T管负压吸引)后痊愈出院;无其他严重并发症发生。术后住院时间(9.34±3.39)d;术后胃肠道恢复时间(1.84±0.57)d;围手术期内无死亡病例及非计划手术病例。(2)病理情况:术中32例行淋巴结清扫,术后26例病理结果提示胆管细胞癌未行淋巴结清扫;病理学检查结果显示,所有肿瘤切缘的病理报告均为阴性,4例淋巴结清扫并提示淋巴结转移阳性。(3)随访结果:58例ICC患者中,49例获得术后随访,随访时间为6~36个月,术后肿瘤生存时间为4~36个月,28例获得无瘤生存,17例患者出现肝内转移并多发淋巴结转移,4例患者发现肝内转移后行微波消融治疗,9例患者失访。结论腹腔镜肝切除经验丰富的中心,应用腹腔镜治疗肝内胆管细胞癌是安全及可行的。     

腹腔镜肝切除治疗肝血管瘤18例

目的探讨腹腔镜肝切除治疗肝血管瘤的可行性。方法2002年1月至2006年10月共治疗18例肝血管瘤患者,应用腹腔镜下肝门阻断器阻断第一肝门的血流后,使用电刀、超声刀等方法断肝,肝断面采用腹腔镜下肝针缝合并喷洒生物蛋白胶等方法处理,行腹腔镜肝段或局部切除10例、行左肝外叶切除术5例、行规则性左半肝切除术2例、行不规则性左半肝切除术1例;其中合并胆囊切除2例、合并阑尾切除1例。结果18例患者手术均获得成功,手术时间（185．4±55．7）min;术中出血（416．2±128．8）ml;术后恢复顺利,无严重并发症,患者住院时间（6．2±1．0）d。结论腹腔镜肝切除治疗肝血管瘤安全、可行。     

腹腔镜左半肝切除治疗肝内胆管结石的临床研究

目的探讨腹腔镜左半肝切除治疗肝内胆管结石的可行性。方法 9例肝胆管结石的病例,经应用电刀、超声刀等断肝方法,肝断面采用腔镜下用肝针缝合,并喷洒生物蛋白胶等处理方法,行腹腔镜左半肝切除术,其中行规则性左半肝切除术2例,不规则性左半肝切除术7例;合并胆囊切除7例。结果 9例病人手术均获得成功,手术时间(289.44±25.05)min;术中出血(308.89±65.28)ml;术后恢复顺利,无并发症,病人住院时间(6.67±1.22)d;残石率0(0/9)。结论腹腔镜左半肝切除治疗肝胆管结石安全、可行,具有微创的优点;可作为治疗肝胆管结石的一种新的选择。     

腹腔镜与开腹二期肝切除治疗结直肠癌肝转移的短期疗效比较

【摘要】 目的 探讨腹腔镜肝切除与开腹肝切除对结直肠癌肝转移的短期疗效。方法 自2008年1月至2012年12月,对94例结直肠癌肝转移患者行二期肝切除,其中腹腔镜手术46例,开腹手术48例,收集并比较两组患者的短期疗效资料。所有患者中,左半肝切除35例,右半肝切除28例,不规则楔形切除术31例;原发结直肠癌切除后3~6个月再次采取手术进行肝内病灶切除。 结果 腹腔镜肝切除的结直肠癌肝转移患者术中出血量较开腹组明显减少(P<0.05),住院时间显著缩短(P<0.05),且具有较低的术后谷丙转氨酶、谷草转氨酶、胆红素及白细胞水平(P<0.05)。两组并发症发生率差异无统计学意义。 结论 对于结直肠癌肝转移二期肝切除患者,腹腔镜手术安全可靠,术后短期疗效较开腹好。     

Glisson蒂横断法在腹腔镜左肝段切除术中的应用

目的:探讨应用Glisson蒂横断法行腹腔镜左肝段切除术的可行性及技术要点。方法:回顾分析2015年1月至2016年10月为14例患者行腹腔镜下Glisson蒂横断法左肝段切除术的临床资料。观察手术时间、术中出血量、住院时间、术后并发症、近期及远期疗效等指标。结果:14例患者均成功施行腹腔镜下Glisson蒂横断法左肝段切除术,无一例中转开腹,其中肝左外叶切除5例、左半肝切除4例,Ⅱ、Ⅲ段肝切除各2例,Ⅳ段肝切除1例。手术时间100~240 min,平均(140.6±89.3)min;术中出血量150~300 ml,平均(200.5±95.7)ml;住院5~10 d,平均(7.8±2.4)d;无手术并发症发生,随访早期无肿瘤复发与转移。结论:腹腔镜下Glisson蒂横断法左肝段切除术的优势在于迅速、精确的到达Glisson蒂左肝段分支,适于左半肝、左外叶及Ⅱ、Ⅲ、Ⅳ段的肝肿瘤,手术安全、可行,可在很大程度上简化腹腔镜肝段切除术。     

腹腔镜规则性左半肝切除联合胆道镜取石治疗肝内外胆管结石

目的：探讨腹腔镜下规则性左半肝切除联合胆道镜取石治疗肝左叶肝内胆管结石合并胆总管结石的临床疗效。 方法：回顾性分析2010年3月—2013年9月间收治的12例肝内外胆管结石患者的临床资料。患者术前均明确诊断为左肝内广泛胆管结石合并胆总管结石,均行腹腔镜规则性左半肝切除联合胆总管切开胆道镜取石术。 结果：所有手术均顺利完成,无中转开腹。手术用时（182.6±36.3）min,术中出血（213.5±65.5）mL,术后肛门排气时间（38.5±8.2）h,术后平均住院时间（10.3±3.1）d。术后发生肝断面出血1例,胆瘘1例,均通过保守治疗痊愈。随访时间3个月至3年,平均23个月,未发现胆道结石残留或再生。 结论：对于肝左叶广泛肝内胆管结石合并胆总管结石的患者,腹腔镜规则性左半肝切除联合胆道镜行胆总管切开取石术是安全有效的手术方式。

     

腹腔镜左半肝切除术的临床应用研究

目的探讨应用腹腔镜手术完成左半肝切除术的可行性。方法腹部Trocar的置放同LC,剑突下Trocar的置放于左肋弓下距中线3cm。CO2气腹压力10~12mmHg。超声刀切断镰状韧带、冠状韧带、做左三角韧带,切除胆囊。肝门血流阻断方式分别采用间歇性阻断2例、不阻断7例、选择性阻断23例。从胆囊窝中点向肝门左侧方向,应用超声吸引刀、双极电凝等器械向肝实质内分离至肝门左侧方。解剖左肝管、左门静脉横部后,将其分别结扎切断。肝内分离结扎切断肝左静脉,切除左半肝。结果 32例均行左半肝切除、胆道探查、T管引流术。手术均获成功,手术时间150~390min,平均190min。出血量280~1100ml,平均550ml。术后胆漏3例,引流治愈。1例术后4d肝创面急性大出血,腹腔镜下止血成功。多发性肝脓肿1例,反复超声引导下肝穿,术后6个月治愈。膈下脓肿1例,超声引导下穿刺治愈。32例随访6~12个月,均健在,无复发。结论腹腔镜左半肝切除术可行,术后恢复快,但行此类手术应慎重,一要具备相应的设备器械,二要有开腹肝切除和腹腔镜手术经验的医师行此手术。     

Laparoscopic resection of colon cancer and synchronous liver metastasis

The recommended surgical approach to synchronous colorectal metastasis has not been clarified. Simultaneous open liver and colon resection for synchronous colorectal carcinoma has been shown beneficial when compared to staged resections. A review of the literature has shown the benefits of both laparoscopic colon resection for colorectal cancer and laparoscopic left lateral segmentectomy in liver disease. We present the case of a 60-year-old male with sigmoid colon carcinoma and a synchronous solitary liver metastasis localized to the left lateral segment. Using laparoscopic techniques, we were able to achieve simultaneous resection of the sigmoid colon and left lateral liver segment.     

Simultaneous laparoscopic resection of colorectal cancer and synchronous metastatic liver tumor

Laparoscopic colorectal resection has been applied to advanced colorectal cancer. Synchronous liver metastasis of colorectal cancer would be treated safely and effectively by simultaneous laparoscopic colorectal and hepatic resection. Seven patients with colorectal cancer and synchronous liver metastasis treated by simultaneous laparoscopic resection were analyzed retrospectively. Three patients received a hybrid operation using a small skin incision, 2 patients underwent hand-assisted laparoscopic surgery using a small incision produced for colonic anastomosis, and 2 patients were treated with pure laparoscopic resection. The mean total operation duration was 407 minutes, and mean blood loss was 207 mL. Negative surgical margins were achieved in all cases. Mean postoperative hospital stay was 16.4 days. No recurrence at the surgical margin was observed in the liver. For selected patients with synchronous liver metastasis of colorectal cancer, simultaneous laparoscopic resection is useful for minimizing operative invasiveness while maintaining safety and curability, with satisfying short- and long-term results.     

完全腹腔镜治疗结肠癌伴同时性肝转移的临床疗效

目的：探讨腹腔镜下行结肠癌根治术与肝转移灶切除术的安全性及疗效。 方法：选择2009年3月―2011年4月收治的50例结肠癌同时性肝转移患者,其中25例患者行腹腔镜下结肠癌根治术及肝转移灶切除术（腹腔镜组）,另25例在传统开腹手术（开腹组）。比较两组患者的术中情况、术后恢复情况以及术后1、2、3年生存率。 结果：腹腔镜组的术中出血量、术后镇痛时间、排气时间、住院时间及并发症均明显少于开腹组（P<0.05）,但两组的手术时间差异无统计学意义（P>0.05）。两组患者术后1、2、3年生存率差异无统计学意义（均P>0.05）。 结论：完全腹腔镜治疗结肠癌伴同时性肝转移安全可行,与开腹手术疗效相同,同时具有创伤小、术后恢复快、并发症少等优点。     

Laparoscopic-Assisted Combined Colon and Liver Resection for Primary Colorectal Cancer with Synchronous Liver Metastases: Initial Experience

BACKGROUND: Laparoscopic approaches have become increasingly used in selected patients with either colorectal or liver cancer. However, the feasibility of laparoscopic-assisted combined colon and liver resection in primary colorectal cancer with synchronous liver metastases remains unknown. The aim of the present study was to determine the feasibility of laparoscopic-assisted combined colon and liver resection for primary colorectal cancer with synchronous liver metastases. METHODS: Laparoscopic surgery involving intestinal anastomosis was performed for primary colorectal cancer. The liver was then mobilized with the assistance of a hand inserted through the upper midline incision. For minor resections, the parenchymal transection was performed laparoscopically. For major resection involving a hilar dissection, transection was performed according to the standard open techniques under direct vision through the incision. Resected specimens were retrieved directly through the midline incision. RESULTS: Ten patients with primary colorectal cancer and synchronous liver metastases underwent the above procedure between September 2006 and April 2007. Surgical procedures for colorectal cancer included 5 low anterior resections, 3 anterior resections, 1 right hemicolectomy, and 1 subtotal colectomy. Combined hepatic surgery included 6 major hepatectomies, 3 segmentectomies, and 1 tumorectomy. All procedures were successful, with no conversions to open surgery required. The median operation time was 439 min (range: 210-690 min), and the median estimated blood loss was 350 ml (range: 300-1,200 ml). There was no surgical mortality or major morbidity, except in one patient in whom postoperative bleeding at the site of para-aortic node dissection was promptly controlled. CONCLUSIONS: Laparoscopic-assisted combined colon and liver resection is a feasible and safe procedure for the treatment of primary colorectal cancer with synchronous liver metastases.     

Simultaneous resection of colorectal cancer and liver metastases in the right lobe using pure laparoscopic surgery

It is now common to resect colorectal cancer by laparoscopic surgery. Hepatectomy has become a standard treatment for patients with colorectal cancer with resectable liver metastases. The resection of liver tumors can now be done partly by laparoscopic surgery. However, metastatic tumors in the right lobe are often difficult to resect laparoscopically. Furthermore, simultaneous resection of the colorectum and liver may also be difficult. In this study, we evaluated a new method to resect both colorectal cancer and liver metastases in the right lobe by laparoscopic surgery. Two cases are presented that underwent total laparoscopic resection of a right lobe tumor, associated with laparoscopic colorectal resection. The metastatic tumor in the right lobe was first resected in the left hemi-prone position. Then, the colorectal cancer was resected in the lithotomy position. The method for resecting the right lobe liver tumor and colorectal cancer was safe and feasible. The mean duration of surgery was 443.5 min, and the mean blood loss was 158 mL. The postoperative course was uneventful. In selected patients, laparoscopic hepatectomy for right lobe synchronous metastatic tumors can be safely performed simultaneously with colorectal surgery.     

Totally laparoscopic strategies for the management of colorectal cancer with synchronous liver metastasis

Introduction

Laparoscopy is an accepted treatment for colorectal cancer and liver metastases, but there is no consensus for its use in the management of synchronous liver metastases (SCRLM). The purpose of this study was to evaluate totally laparoscopic strategies in the management of colorectal cancer with synchronous liver metastases.

Methods

Patients presenting to Ninewells Hospital between July 2007 and August 2010, with adenocarcinoma of the colon and rectum with synchronous liver metastases were considered. Patients underwent simultaneous laparoscopic liver and colon cancer resection, a staged laparoscopic resection of SCRLM and colon cancer, or simultaneous colon resection and radiofrequency ablation (RFA) of SCRLM. Primary endpoints were in-hospital morbidity and mortality, total hospital stay, intraoperative blood loss, duration of surgery, and resection margin status.

Results

Twenty-eight patients presented with synchronous colorectal liver metastases. Thirteen patients underwent a simultaneous laparoscopic liver and colon resection (median operating time, 370 (range, 190–540) min; median hospital stay, 7 (range, 3–54) days), seven patients had a staged laparoscopic resection of SCRLM and primary colon cancer (median operating time, 530 (range, 360–980) min; median hospital stay 14, (range, 6–51) days), and eight patients underwent laparoscopic colon resection and RFA of SCRLM (median operating time, 310 (range, 240–425) min; median hospital stay, 8 (range, 6–13) days). There were no conversions to an open procedure. Overall in-hospital morbidity and mortality was 28 and 0?% respectively. An R0 resection margin was achieved in 91?% of the resection group. At a median follow-up of 26 (range, 18–55) months, 19 (90?%) patients remain disease-free.

Conclusions

Totally laparoscopic strategies for the radical treatment of stage IV colorectal cancer are feasible with low morbidity and favorable outcomes. A laparoscopic approach for the simultaneous management of SCRLM and primary colon cancer is associated with reduced surgical access trauma, postoperative morbidity, and hospital stay with no compromise in short-term oncological outcome.     

Simultaneous Laparoscopic Anterior Resection and Left Hepatic Lobectomy for Stage IV Rectal Cancer

We report the case of a 68-year-old female patient affected by rectal cancer and a synchronous metastatic lesion measuring 8cm in diameter in the left hepatic lobe. After a laparoscopic ultrasonography exploration of the liver to detect possible occult metastases, a simultaneous colorectal resection and a left hepatic lobectomy including a partial resection of segment IV were performed. Five ports were used for the entire procedure. The resected specimens were extracted through a Pfannenstiel incision. The procedure was completed laparoscopically. Total operative time was 455 minutes with negligible intraoperative blood loss. The postoperative hospital stay was 12 days. At 4-month follow-up, the patient recovered completely. A computed tomography scan performed at this time showed no signs of recurrent disease. This report confirms the feasibility of the laparoscopic approach to simultaneous hepatic and colorectal resections in stage IV rectal cancer. The known advantages of the mini-invasive approach could make such complex procedures more endurable.     

Habib 4X双极射频在腹腔镜肝切除术中的应用

目的 本研究应用Habib 4X双极射频辅助腹腔镜切肝,以评价其减少术中出血表现及术后并发症情况.方法 回顾性分析2009年9月至2012年4月期间,我院30例Habib 4X射频辅助切肝病例的临床资料.结果 30例中,1例因术中瘤体破溃中转开腹手术,29例完成腹腔镜下手术.其中左肝外叶切除12例,左半肝切除1例,第Ⅴ段或第Ⅵ段切除8例,ⅤⅥ段联合切除2例,肝缘病灶锲型切除6例.切肝时间10~68 min,中位切肝时间22 min;出血量8~370 mL,平均(145±75) mL;术后住院时间(3~12)d,平均(7.5±2.8)d.无术后出血、胆漏或感染等并发症,肝癌病例术后未见切缘复发.结论 应用Habib4X射频辅助腹腔镜切肝,无需肝门解剖和阻断,可提高切肝速度,减少术中失血,术后恢复快,不增加术后并发症.由于射频本身的治疗作用,肿瘤性病灶切除后可增加切缘的安全性.     

完全腹腔镜肝切除时出血问题的探讨

目的　探讨腹腔镜肝切除手术的出血原因和预防措施。　方法　 2 1例中包括原发性肝癌 13例、肝血管瘤 3例、肝脓肿 2例、肝囊肿伴感染、局灶结节性增生、肝脏腺瘤各 1例。肝功能Child分级 :A级 16例 ,B级 5例 (均为肝癌病人 )。　结果　 2 1例在全气腹条件下完成腹腔镜肝切除手术 ,包括肝局部切除 12例 ,左肝解剖性切除 9例。手术时间 80～ 32 0 (平均 193 8± 78 3)min ,出血量 10 0～ 10 0 0ml (平均 333 1± 2 91 4 )ml,有 2例出血 10 0 0ml,术中输血各 80 0ml。术后恢复顺利 ,术后平均住院时间 6 3± 1 5d ,术后恢复时间较常规开腹方法肝切除患者明显缩短。　结论　本组研究表明在现有的手术器械条件和不阻断肝门血流的情况下 ,可以安全方便地处理术中出血。腹腔镜肝切除微创手术的前景广阔 ,不仅适于对肝良性肿瘤的手术 ,也为肝脏恶性肿瘤患者提供了切除肿瘤的新途径     

腹腔镜技术在梗阻性左半结肠癌中的应用体会

目的 探讨腹腔镜技术在治疗梗阻性左半结肠癌中的安全性及可行性。方法 回顾性分析2018年10月至2019年10月广东省陆丰市人民医院普外科10例行腹腔镜左半结肠癌根治术患者的临床资料。结果 10例患者均全部顺利完成腹腔镜左半结肠癌根治术,无中转开腹。手术中位时间为171（132~230）min,术中中位出血量为60（20~250）mL,10例患者均行一期切除吻合和预防性回肠造口,中位腹部切口长度为8（9~10）cm,中位淋巴结清扫总数17（12~25）个。术后第1天均恢复流质饮食,术后排气中位时间为1（1~3）天,术后拔除引流管时间1（1~2）天,术后住院中位时间为7（6~12）天。结论 腹腔镜技术在治疗梗阻性左半结肠癌中是安全可行的,具有一定的临床应用价值。