肿瘤与血管接触三级评价法在胰腺癌术前评价中的价值

目的 探讨多排螺旋CT(multidetector CT, MDCT)肿瘤与血管接触（tumor vessel contact, TVC）三级评价法在胰腺癌术前评价中的应用价值。方法 选取2017年1月至2019年3月在河南省南阳市中心医院行手术治疗的胰腺癌患者80例,术前给予MDCT检查,比较TVC三级评价法与手术探查结果的一致性。结果 80例患者,手术中共探查408支胰周血管,其中腹腔干81支,肝总动脉87支,肠系膜上动脉82支,肠系膜上静脉76支,门静脉81支;与TVC三级评价法分析一致性κ检验结果分别为0.770、0.731、0.697、0.509和0.688,P<0.05;TVC三级评价法显示侵犯的周围器官主要为十二指肠,诊断胰周血管侵犯可切除的灵敏性、特异性、阳性预测值和阴性预测值分别为100.00%、62.50%、96.07%和100.00%。肿物侵犯周围器官主要为十二指肠;CT诊断肿物可切除的灵敏性、特异性、阳性预测值和阴性预测值分别为78.00%、79.50%、80.00%和77.50%。结论 进行TVC三级评价法在可手术胰腺癌患者术前评价中有较好的应用价值,值...     

多层螺旋CT诊断冠状动脉疾病的发展趋势

多层螺旋CT（multidetector spiral computed tomography，MDCT）在CAD诊断领域的主要适应证有：测定冠状动脉钙化积分（coronary artery calcium score，CACS）、CT冠状动脉造影、评价心肌功能及冠心病（coronary artery disease，CAD）在治疗后的随访。据报道，CACS用于诊断CAD的敏感性范围在68．0％～100％，特异性范围在21．0％～100％。高CACS是一个敏感性很高但特异性相对较低的指标，与常规冠状动脉造影（coronary angiography，CAG）相比，16排MDCT的冠状动脉造影在诊断冠状动脉狭窄（350％）时具有中高度敏感性和高度阴性预测值（negative predictive value，NPV）。与之相比，64排MDCT的敏感性和NPV更高，但特异性与阳性预测值（positive predictive value，PPV）却无明显提高。将冠状动脉形态学与心肌灌注功能研究相结合，是今后CAD的研究方向。     

多层螺旋CT评价靶血管通畅性图像的质量:冠状动脉支架材料及其结构有影响吗?

背景:由于金属材料对多层螺旋CT图像有伪影干扰作用,支架结构中金属管壁厚度和管腔内径也可明显影响多层螺旋CT靶血管支架内纵轴成像质量,但目前仅有少量报道涉及到这方面的问题.目的:观察不同材料的冠状动脉支架及其结构对多层螺旋CT评价靶血管通畅性图像质量的影响,希望实验数据能为改进和完善支架技术提供参考.设计、时间及地点:对比观察,于2006-01/2008-12在沈阳医学院沈洲医院及中国医科大学附属盛京医院完成.对象:纳入接受支架置入的冠状动脉粥样硬化性心脏病患者139例,共置入支架227枚,按置入支架材料和结构分组.不锈钢支架92枚,镍钛合金支架135枚:薄金属壁支架(<140 μm)85枚,厚金属壁支架(≥140 μm)142枚;小直径支架(<3 mm)71枚,大直径支架(≥3 mm)156枚.方法:随访期间采用64层螺旋CT机进行冠状动脉扫描,并做常规冠状动脉造影检查,比较不同组别靶血管通畅性图像质量的差异.主要观察指标:采取4分制进行多层螺旋CT图像质量评分,评价多层螺旋CT的敏感度、异度、准确度、阳性预期值与阴性预期值.结果:139例患者共置入支架227枚,按支架材料分组后,不锈钢支架组CT图像质量较差处明显多于镍钛合金组,前者的平均CT图像质量评分、敏感性、特异性、阳性和阴性预测值均明显低于镍钛合金组(P均<0,05).按支架厚度分组后,厚会属壁支架组CT图像质量较差处明显多于薄金属壁支架组,前者的平均CT图像质量评分、敏感性、特异性、阳性和阴性预测值均明显低于薄金属壁支架组(P均<0.05).按支架直径分组后,小直径支架组CT图像质量较差处明显多于大直径支架组,前者的平均CT图像质量评分敏感性、特异性、阳性和阴性预测值均明显低于大直径支架组(P均<0.05).结论:冠状动脉支架金属材料、金属壁厚度和管腔直径均可能影响多层螺旋CT靶血管成像质量.     

急性肠系膜缺血性疾病早期CT血管成像影像特征分析

目的探讨急性肠系膜缺血性疾病（AMI）早期CT血管成像（CTA）的影像特征,为AMI的早期诊断提供参考。方法回顾性分析9例AMI患者的CTA检查资料。结果 9例中1例发现肠系膜上动脉血栓,1例发现肠系膜上动脉分支血栓,2例发现肠系膜下动脉血栓,1例发现肠系膜上静脉血栓,1例发现肠系膜上静脉分支血栓,3例发现肠系膜下静脉血栓;2例行数字减影血管造影（DSA）检查确诊肠系膜上动脉及分支血栓;9例血栓性肠坏死,治愈4例（44.44%,4/9）,死亡5例（55.56%,5/9）。结论 AMI早期诊断困难,病情发展迅速,病死率高;早期诊断CT检查诊断意义不大,CTA以及选择性肠系膜DSA检查有确诊意义;CTA在AMI的早期诊断中有重要意义。     

Added value of CT myocardial perfusion imaging

Multidetector CT angiography (MDCTA) has become an accurate, noninvasive test for the diagnosis of coronary atherosclerosis. Studies have established a good sensitivity and an excellent negative predictive value for the diagnosis of coronary stenoses of 50% or greater severity. However, MDCTA is more limited in patients with disease with a lower specificity and positive predictive value for predicting atherosclerosis causing myocardial ischemia. Although radionuclide myocardial perfusion imaging (MPI) has been the mainstay for evaluating the presence of myocardial ischemia and scar in patients at risk for coronary artery disease, contrast-enhanced multidetector CT (MDCT) alone, with or without vasodilator stress, has the potential to provide both anatomical and functional information on coronary atherosclerosis and its impact on myocardial perfusion. We review the current status of MDCT MPI, including its advantages, limitations, and pitfalls.     

Sixty-Four-Slice Multidetector Computerized Tomography in the Evaluation of Transmesenteric Internal Hernias following Roux-en-Y Bariatric Surgery

Objective

To evaluate the accuracy of 64-slice multidetector computerized tomography (MDCT) in the detection of transmesenteric internal hernias in patients following Roux-en-Y gastric bypass (RYGB) for bariatric surgery patients.

Subjects and Methods

This retrospective study was performed on post-bariatric RYGB patients presenting with signs and symptoms suggestive of internal hernias at our institution from the period of April 2010 until March 2012. The patients who had symptoms suggestive of internal hernia had undergone 64-slice MDCT. All the patients who on CT examination were found to have features suggestive of internal hernia were subjected to laparoscopic exploration.

Results

Of the 102 patients who had undergone laparoscopic RYGB, 42 (41.2%) were suspected of having internal hernia. Of these, 23 (55%) had CT findings of hernia while the remaining 19 (45%) were considered normal. Of the 23, 21 (91%) patients were confirmed for internal hernia at laparoscopy. The 19 (45%) patients that did not reveal any signs for internal hernia on CT and the 2 patients that were considered normal on laparoscopy were treated conservatively. The sensitivity, specificity and positive and negative predictive values for MDCT in the diagnosis of internal hernias were 100, 90.5, 91 and 91.3% respectively.

Conclusion

The 64-slice MDCT was accurate in the diagnosis of transmesenteric internal hernias in post-RYGB for bariatric surgery patients. The presence of clustered loops with mesenteric swirl is a reliable indicator of transmesenteric internal hernia.Key Words: Internal hernia, Bariatric surgery, Computerized tomography, Roux-en-Y, Gastric bypass     

Blunt bowel and mesenteric injury: MDCT diagnosis

Multidetector computed tomography (MDCT) has emerged as the imaging modality of choice for evaluating the abdomen and pelvis in trauma patients. MDCT readily detects injury of the solid organs as well as direct and indirect features of bowel and/or mesenteric injury—an important advance given that unrecognized bowel and mesenteric injuries may result in high morbidity and mortality. Nonetheless, challenges persist in the interpretation of abdominal and pelvic CT images in trauma patients. Difficulty in interpretation may result from lack of familiarity with or misunderstanding of CT features of bowel and/or mesenteric injury. Moreover, due to major technical advances afforded by MDCT, new CT features of bowel and/or mesenteric injuries have been recognized. Beading and termination of mesenteric vessels indicating surgically important mesenteric injury is an example of one of these new features. MDCT also allows for the detection of small or trace amounts of isolated intraperitoneal fluid in trauma patients, although the clinical management of these patients is still controversial. This pictorial essay illustrates the spectrum of typical, atypical, and newly reported MDCT features of bowel and mesenteric injuries due to blunt trauma. The features that help to differentiate these injuries from pitfalls are emphasized in these proven cases.     

斑块钙化负荷影响冠状动脉CT血管造影诊断管腔狭窄的准确性

  目的  探究斑块钙化负荷对冠状动脉CT血管造影（CCTA）诊断管腔狭窄准确性的影响。  方法  选取上海市嘉定区中心医院放射科于2019年2月~2022年1月收治的100例患者作为研究对象,所有患者均行冠状动脉造影与CCTA检查,钙化容积与钙化积分以血管段为单位进行记录,按照钙化容积与钙化积分不同将患者分为4组,分析各组血管管腔狭窄程度并探究CCTA判断斑块钙化不同容积与积分的管腔狭窄准确性。  结果  100例患者中入选的钙化冠状动脉段共396个,按照15段进行计算,以管腔狭窄≥50%为有意义狭窄,得到敏感度、特异性、准确率、阳性预测值与阴性预测值分别为99.03%（204/206）、83.16%（158/ 190）、91.41%（362/396）、86.44%（204/236）、98.75%（158/160）;当钙化容积≤25 mm2、钙化积分≤80分时,敏感度、特异性、准确率、阳性预测值、阴性预测值均为100%;当196 mm2<钙化容积≤1375 mm2时,敏感度、特异性、准确率、阳性预测值、阴性预测值分别为85.71%、36.36%、75.47%、83.72%、40.00%;当钙化积分>200分时,敏感度、特异性、准确率、阳性预测值、阴性预测值分别为92.86%、75.00%、87.50%、89.66%、91.82%;CCTA诊断不同钙化容积管腔狭窄程度与不同钙化积分管腔狭窄程度的敏感度、特异性、准确率、阳性预测值、阴性预测值具有统计学意义（P<0.05）,其中诊断0~25 mm2钙化容积管腔狭窄程度与0~80分钙化积分管腔狭窄程度的敏感度、特异性、准确率、阳性预测值、阴性预测值最高。  结论  不同斑块钙化负荷对CCTA诊断管腔狭窄程度准确性的影响存在差异,应引起临床重视。      

How to differentiate spontaneous intramural intestinal hemorrhage from acute mesenteric ischemia

ObjectsThe purpose of our study was to assess the diagnostic values of laboratory tests to differentiate spontaneous intramural intestinal hemorrhage (SIIH) from acute mesenteric ischemia (AMI) after abdominal computed tomography (CT) survey in the emergency department (ED).MethodWe retrospectively included 76 patients diagnosed SIIH or AMI after abdominal CT.ResultsThe mean ages of 28 SIIH patients and 48 AMI patients were 75.9 ± 13.7 years and 75.8 ± 11.6 years, respectively. Patients with SIIH had significantly higher rate of Coumadin use (P < .001) and localized tenderness (P < .05). In laboratory findings, SIIH patients had prolonged prothrombin time (PT) (83.6 ± 30.0 vs. 13.4 ± 3.2, P < .001), lower blood urea nitrogen (P < .05), lower creatinine (P < .05), and lower creatine kinase (P < .05). Prolonged PT showed good discriminative value to differentiate acute abdomen patients with SIIH from AMI after abdominal CT, with an area under the receiver operating characteristic curve of 0.980 (95% confidence interval, 0.918-0.998; P < .0001). Prolonged PT cut-off value of ≧ 22.5 seconds had a sensitivity of 92.9% and a specificity of 100%. Logistic regression analysis identified prolonged PT as an independent predictor of SIIH (odds ratio, OR, 22.2; P = .007).ConclusionAbdominal pain patients with either SIIH or AMI are rare in the ED, but abdominal CT sometimes cannot help to differentiate them due to similar CT findings. Prolonged PT might help emergency physicians and surgeons differentiate SIIH from AMI in such cases.     

Evaluation of the clinical usefulness of a chemiluminometric method for measuring creatine kinase MB

The use of creatine kinase isoenzymes (CK-MB) in the diagnosis of acute myocardial infarction (AMI) is well established. We evaluated the use of a new chemiluminometric method (CK-Ciba) for measuring CK-MB by calculating its sensitivity, specificity, positive and negative predictive values, and diagnostic efficiency for diagnosing AMI. We tested 633 samples from 229 patients within 4 h of receipt. The patients were divided into four groups: (1) patients who had an AMI, (2) patients who had AMI ruled out, (3) patients who had CK-MB measured for reasons other than to rule out AMI, and (4) patients who had only one sample drawn. Only patients in Groups 1 and 2 were used in the study. AMI was diagnosed by a cardiologist. The prevalence of AMI in our population was 0.18. A receiver-operator characteristic curve was used to establish optimal values for identifying AMI with the CK-Ciba results: CK-MB greater than or equal to 10 micrograms/L and a CK-MB index of greater than or equal to 3.0 (micrograms of CK-MB per U of CK x 100). Using these values, we calculated a sensitivity of 1.00, specificity of 0.97, positive predictive value of 0.87, negative predictive value of 1.00, and a diagnostic efficiency of 0.97. We conclude that the CK-Ciba method has high sensitivity, high specificity, and good predictive values for CK-MB and is appropriate to use to rule out AMI.     

Computed tomographic evaluation and staging of cecal carcinoma

The preoperative computed tomographic (CT) scans of 14 patients with biopsy-proven primary adenocarcinoma of the cecum were reviewed to assess clinical presentation, CT findings, and value of staging by CT. The correlation of CT evidence for tumor invasion beyond the bowel wall with histopathology had predictive value of negative examination of 33% with sensitivity of 78%. More importantly, the correlation of metastatic nodal involvement by CT had predictive value of negative examination of 22% with sensitivity of only 12%. Of chief concern was the involvement of pericolic and mesenteric nodal chains that were not discernible by CT. Computed tomographic tumor staging was accurate in 57% of cases and upgraded in 43%. This study concludes that, although predictive values of positive CT examination are high, CT tends to underestimate disease extent.     

320排容积CT检查对冠脉支架植入术后患者支架内再狭窄的评价

目的 探讨320排容积CT对冠脉内支架植入术后忠者支架内再狄窄的评估价值.方法 对81例冠心病经皮冠脉介入治疗术后患者的临床资料进行观察分析,以冠脉造影结果为金标准,计算320排容积CT对诊断支架内再狭窄的灵敏度、特异度、阳性预测值、阴性预测值.结果 320排容积CT对支架内再狭窄诊断的灵敏度、特异度、阳性预测值、阴性预测值分别为94.87%、98.1%、92.5%、98.73%.结论 320排容积CT对支架内再狭窄的诊断有较高的阳性预测值,可以用于冠状动脉支架植入术后对冠脉支架的随访.     

Detection of recurrent hepatocellular carcinoma on post-operative surveillance: comparison of MDCT and gadoxetic acid-enhanced MRI

Objective

To compare the accuracy of multidetector computed tomography (MDCT) and gadoxetic acid-enhanced magnetic resonance imaging (MRI) for the detection of intrahepatic tumor recurrence after curative resection of hepatocellular carcinoma (HCC).

Materials and methods

Fifty-six patients who underwent MDCT and gadoxetic acid-enhanced MRI for postoperative surveillance after resection of HCC were retrospectively analyzed; 26 patients had a recurrence (36 lesions) and 30 patients did not. Recurrent HCCs were confirmed by histological examinations in two, typical dynamic imaging findings on CT and/or MRI in 28, and by demonstration of growth or tumor staining on angiography on six. Two reviewers graded the confidence for the presence of recurrence on CT and MRI, using a five-point scale. The jackknife free-response receiver operating characteristic method was used to compare diagnostic performance. The accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated.

Results

For 36 recurrent lesions, the figure of merit was significantly higher for MRI than MDCT for detecting recurrence for both reviewers (p < 0.005 for both reviewers). In lesion-by-lesion analysis, the sensitivity was significantly higher on MRI (100% for reviewer 1 and 97% for reviewer 2) than on MDCT (44.4% and 66.6%) for both reviewers (p < 0.005 for both reviewers). Also in patient-by-patient analysis, sensitivity was significantly higher on MRI (100% and 96.1%) than on MDCT (57.6% and 76.9%) for both reviewers (p < 0.05 for both reviewers).

Conclusion

Gadoxetic acid-enhanced MRI is superior to MDCT for detecting intrahepatic recurrence after curative resection of HCC.     

Evaluation of In-Stent Restenosis by High Spatial Resolution CT

Multidetector row CT has been established as a noninvasive method for the detection of coronary artery disease. In previous studies, the diagnostic accuracy of 64-slice CT for the detection of in-stent restenosis usually displayed high sensitivity and negative predictive value, while specificity and positive predictive values were too low to allow its utilization in clinical practice. Especially in small stents—with a diameter below 3.0 mm—the accuracy of CT angiography to detect in stent stenosis has been low. Recently, CT systems with improved in-plane spatial resolution (high-definition CT, HDCT) have become commercially available. Furthermore, an experimental CT (fine-cell detector CT, FDCT) has been developed using half pitch dimension detector cells in both X and Z directions compared with 64-slice CT. Compared with that in conventional 64-slice CT, the spatial resolution was 30% improved in HDCT and 60% improved in FDCT, and the lumen visibility was 1.3 times improved in HDCT and 1.5 times improved in FDCT. The diagnostic accuracy of in-stent restenosis with HDCT was higher than 90% in both sensitivity and specificity, moderate (77%) in positive predictive value, and very high (98%) in negative predictive value. FDCT is not yet applicable to patients, however, further improvement of diagnostic accuracy in the evaluation of in-stent restenosis is expected in FDCT. In the near future, cardiac CT could reach the diagnostic performance to replace invasive catheter angiography, and would be the appropriate noninvasive technique for diagnosis of in-stent restenosis.     

Diagnostic value of coronary CT angiography with prospective ECG-gating in the diagnosis of coronary artery disease: a systematic review and meta-analysis

To perform a systematic review and meta-analysis of the diagnostic value of prospective ECG-gating coronary CT angiography in the diagnosis of coronary artery disease. A search of biomedical databases for English literature was performed to identify studies investigating the diagnostic value of 64- or more slice CT angiography with use of prospective ECG-gating in the diagnosis of coronary artery disease. Sensitivity, specificity, positive and negative predictive value estimates pooled across studies were tested using a fixed effects model. Fourteen studies met selection criteria for inclusion in the analysis. Pooled estimates and 95% confidence interval (CI) of sensitivity, specificity, positive and negative predictive value of prospective ECG-gating coronary CT angiography for diagnosis of significant coronary stenosis were 99% (95% CI: 98, 100%), 91% (95% CI: 88, 94%), 94% (95% CI: 91, 96%) and 99% (95% CI: 97, 100%), according to the patient-based assessment. The mean values of sensitivity, specificity, positive and negative predictive value of prospective ECG-gating coronary CT angiography were 95% (95% CI: 93, 96%), 95% (95% CI: 93, 95%), 88% (95% CI: 86, 90%), and 98% (95% CI: 97, 98%), according to vessel-based assessment; 92% (95% CI: 90, 93%), 97% (95% CI: 97, 98%), 84% (95% CI: 82, 86%), 99% (95% CI: 99, 99%), according to segment-based assessment, respectively. The mean effective dose was 3.3 mSv (95% CI: 2.3, 4.1 mSv) for the prospective ECG-gating coronary CT angiography. This analysis shows that for a predominantly male population with a high disease prevalence the use of coronary CT angiography with prospective ECG gating allows for a reduced radiation exposure without a sacrifice in diagnostic efficacy.     

螺旋CT血管造影评价胰腺癌可切除性的意义

目的探讨螺旋CT血管造影（SCTA）诊断胰腺癌胰周血管侵犯及评价可切除性的价值。方法10例疑有局部浸润的胰腺癌患者术前行横断面CT及螺旋CT血管造影检查。比较分析SCTA与横断面CT诊断肿瘤侵犯胰周血管情况以及评价肿瘤可切除性。结果SCTA诊断胰周血管侵犯的敏感度、阴性预测值（100％、100％）高于横断面CT（81．8％、92．6％）。两者差异有统计学意义（P〈0．05）。SCTA术前评价胰腺癌可切除性的阳性预测值高于横断面CT。结论SCTA可精确地诊断胰腺癌侵犯胰周血管的情况，术前可准确评价胰腺癌可切除性。     

双源CT血管成像诊断急性肠系膜缺血价值

目的探讨双源CT血管成像（dual—sourceCTangiography,DSCTA）在急性肠系膜缺血（acutemesentericischemia,AMI）诊断中的价值。方法回顾性分析14例经手术或介入治疗证实AMI患者的DSCTA影像资料。结果14例患者中肠系膜上动脉栓塞2例,肠系膜上动脉血栓形成6例,肠系膜上静脉血栓形成3例（1例合并门静脉血栓）,肠系膜上动脉重度狭窄1例,表现为血管突然中断,管腔内充盈缺损,管壁增厚,管腔变小,钙化影;肠系膜上动脉夹层2例,显示为真假双腔,内膜片清晰。间接征象为不同程度肠腔扩张,肠管内气液平,肠壁增厚或变薄,腹腔积液。增强扫描时肠壁不强化或强化延迟、减弱。结论DSCTA可准确显示AMI直接征象,是较理想的影像学检查方法。     

急性不典型胸痛患者320排CT心肺血管一站式成像分析

目的：探讨320排CT心肺血管一站式成像对急性不典型胸痛的诊断价值。方法收集79例表现为急性胸痛行320排CT心肺血管一站式成像检查的连续病例资料。对比剂使用三期双流速方案同时显示肺动脉、冠状动脉和胸主动脉,并测量三大血管强化CT值,评价图像质量及右心腔对比剂伪影。以传统冠状动脉血管造影为金标准,分析CTA诊断冠状动脉狭窄超过50%的准确性。结果所有患者肺动脉、冠状动脉、胸主动脉均得到良好强化。可诊断冠状动脉血管段比例为95.69%,仅有2例右心腔对比剂伪影影响右冠状动脉评价。所有患者中,22例结果为阴性,肺栓塞13例;胸主动脉病变16例,其中主动脉夹层9例,壁内血肿2例,穿透性溃疡3例,胸主动脉瘤2例;冠状动脉病变为17例,其中7例冠状动脉狭窄超过50%。以血管段为计算单位,CTA诊断冠状动脉狭窄的敏感性、特异性、阳性预测值、阴性预测值、准确度为90.91％、97.65％、83.33％、98.81％、96.88％。结论320排CT心肺血管一站式成像能快速排查肺动脉、冠状动脉和胸主动脉病因,是急性胸痛鉴别诊断的有效方法。     

Accuracy of dual-source CT to identify significant coronary artery disease in patients with uncontrolled hypertension presenting with chest pain: comparison with coronary angiography

It has been previously reported that the sensitivity and specificity of multislice CT for detecting significant CAD (coronary artery disease) is high. Chest pain is a common presentation in patients with uncontrolled hypertension. We investigated the sensitivity and specificity of Dual-Source CT to detect and rule out significant CAD in patients presenting with uncontrolled hypertension accompanied by chest pain. 260 consecutive patients presenting with acute chest pain in the context of stage 2 hypertension (systolic pressure ≥160 and/or diastolic pressure ≥100) were enrolled in the study. After admission, control of blood pressure and risk stratification, 82 patients were excluded due to renal insufficiency, prior coronary revascularisation or refused participation in the study. 90 further patients with low pre-test probability of CAD were also excluded. 88 remaining patients were subjected to CT coronary angiography using Dual-Source CT (Definition, Siemens Medical Solutions, Forchheim, Germany) within 24 h before invasive coronary angiography. A contrast-enhanced volume dataset was acquired (120 kV, 400 mAs/rot, collimation 2 × 64 × 0.6 mm, retrospective ECG gating). Data sets were evaluated concerning the presence or absence of significant coronary stenoses and validated against invasive coronary angiography. A significant stenosis was assumed if the diameter reduction was ≥50%. 88 patients (mean age 66 ± 11 years, mean heart rate 61 ± 9 bpm) were evaluated regarding the presence or absence of significant CAD (at least one stenosis ≥50% diameter reduction). Mean systolic blood pressure on presentation was 203 ± 20 mmHg and mean diastolic blood pressure was 103 ± 13 mmHg. On a per patient basis, the sensitivity and specificity for Dual-Source CT to detect significant CAD in vessels >1.5 mm diameter was 100% (36/36, 95% CI 90-100) and 90% (47/52, 95% CI 79-97), respectively with a negative predictive value (NPV) of 100% (47/47, 95% CI 92-100) and a positive predictive value (PPV) of 88% (36/41, 95% CI 74-96). On a per artery basis, 352 vessels were evaluated (left main, left anterior descending, left circumflex and right coronary artery in 88 patients, 12 vessels could not be assessed due to either motion artefacts or heavy calcification and were considered positive for stenoses) with a sensitivity of 84% (54/64, 95% CI 72-95) and specificity of 94% (272/288, 95% CI 88-100); NPV was 96% (272/282, 95% CI 90-100) and PPV was 77% (54/70, 95% CI 62-91). Our study demonstrates high sensitivity, specificity and negative predictive value of Dual-Source CT to detect significant CAD in patients presenting with uncontrolled hypertension accompanied by chest pain. Dual-Source CT angiography may be useful to safely rule out coronary artery stenoses and avoid invasive angiograms in these patients.     

血浆D-二聚体检测对肠系膜上动脉血栓的诊断价值

目的 分析血浆D-二聚体检测对肠系膜上动脉血栓的诊断价值.方法 对疑似肠系膜上动脉血栓的78例患者进行选择性肠系膜上动脉造影,阳性者30例为实验组,阴性者48例为对照组,检测所有患者的血浆D-二聚体水平.结果 实验组血浆D-二聚体水平明显增高,与对照组比较差异有统计学意义 （P＜0.05）.D-二聚体检测作为肠系膜上动脉血栓的诊断方法的敏感性为93.3%,特异性为59.6%,阴性预测值为93.5%.结论 血浆D-二聚体检测对于肠系膜上动脉血栓的诊断是一种简单快速的敏感方法,可以作为排除肠系膜上动脉血栓的筛选试验