青光眼滤过术后白内障超声乳化术的临床观察

目的观察青光眼滤过术后经角膜缘切口的白内障超声乳化人工晶体植入术的疗效。方法对38例38眼青光眼滤过术后白内障患者行滤过泡旁角膜缘切口白内障超声乳化人工晶体植入术,观察术中术后并发症、视力、眼压、滤过泡情况。结果术后随访3～6个月,术后视力≥0.5者13眼（34%）,0.3～0.5者21眼（55%）,≤0.3者4眼（11%）。术后眼压均在正常范围（11.23～20.15 mm Hg）。功能性滤过泡无瘢痕化,38只眼全部植入人工晶体,术中无一例后囊膜破裂、眼内出血等并发症。角膜水肿、虹膜反应是术后主要并发症。结论滤过泡旁角膜缘切口白内障超声乳化术安全有效。     

青光眼滤过术后透明角膜切口白内障超声乳化术的临床研究

目的：探讨青光眼滤过术后透明角膜切口白内障超声乳化术的方法及手术对滤过泡、眼压的影响。方法：对2005年1月～2008年12月63例（64眼）青光眼滤过术后白内障患者进行透明角膜切口超声乳化吸出和人工晶体植入术,分析术后视力、眼压及并发症。结果：术后视力较前显著提高,随访0．5—2年59眼视力〉0．3（92．19％）;术后眼压较术前差异无显著性;并发症包括角膜内皮水肿、前葡萄膜反应、前房出血、后囊膜浑浊。结论：青光眼滤过术后白内障采用透明角膜切口行晶状体超声乳化吸出折叠人工晶体植入术手术时间短,操作简单,视力恢复好同时保护了滤过泡、术后眼压稳定。     

双切口青光眼白内障联合手术疗效观察

目的：探讨双切口白内障超声乳化吸除囊袋内人工晶体植入联合青光眼小梁切除术治疗青光眼并发白内障的疗效。方法：回顾分析33例患者35只眼双切口白内障超声乳化吸除囊袋内人工晶体植入联合青光眼小梁切除不做虹膜根切，治疗慢性闭角型青光眼并发白内障患者的临床资料。结果：术后视力较术前显著提高，眼压较术前明显降低。Ⅰ、Ⅱ型功能性滤泡占80％，术后无严重并发症。结论：该手术方法治疗青光眼并发白内障安全、有效、经济。     

青光眼白内障联合手术的临床观察

目的探讨小切口非乳化白内障囊外摘除、人工晶状体植入联合小梁切除(简称联合手术)治疗白内障合并青光眼的手术方法,评价其远期临床效果。方法对52例54眼青光眼合并白内障施行联合手术,术后随访6～32个月,平均19个月,对视力、眼压、滤过泡及其并发症等进行临床观察。结果术后随访视力0．02～0．25者10眼,占18．5%;0．3～0．6者38眼,占70．4%;0．8～1．0者6眼,占11．1%。眼压控制在正常范围(≤21mmHg)者51眼,占94．44%。3眼术后眼压28mmHg左右,用噻吗心安滴眼液滴眼,眼压控制正常,滤过泡呈扁平状的功能性滤过泡46眼,占85．19%。并发症:角膜水肿32眼,上方虹膜片状萎缩3眼,瞳孔不园伴机化膜3眼,人工晶状体瞳孔夹持2眼。结论青光眼合并白内障联合手术远期效果良好。     

经颞侧透明切口超声乳化加人工晶体植入治疗青光眼术后白内障

目的探讨青光眼术后白内障的手术方法、并发症及疗效。方法回顾分析青光眼小梁切除术后白内障经颞侧透明切口超声乳化及人工晶体植入术35例(38眼)的临床资料,观察并发症、疗效。结果 38眼均采取颞侧透明切口行超声乳化及人工晶体植入手术。术中瞳孔不能散大6眼,分离粘连时出血2眼,后囊膜破裂1眼。术后1眼眼压一过性升高。38眼均植入人工晶体。滤过泡无明显变化。角膜内皮无失代偿。术后随访12～36个月。37眼术后视力有不同程度提高,1眼视神经萎缩视力无提高。眼压均在正常范围。结论经颞侧透明切口超声乳化加人工晶体植入治疗青光眼术后白内障是安全有效的手术方法。     

超声乳化人工晶体植入联合复合式小梁切除术治疗青光眼合并白内障的临床观察

目的观察青光眼合并白内障超声乳化人工晶体植入联合复合式小梁切除术的临床效果.方法 对42例43眼青光眼合并白内障行超声乳化人工晶体植入联合复合式小梁切除术,术后随访6个月,观察视力、滤过泡、眼压等情况.结果 39眼矫正视力≥0.4,38眼形成功能性滤过泡,眼压正常,5眼需联合降眼压药物及眼球按摩眼压可达正常.结论 超声乳化人工晶体植入联合复式小梁切除术,能有效控制眼压,迅速恢复视力,是治疗青光眼合并白内障的一种安全、有效的方法.     

抗青光眼术后白内障超声乳化术的临床观察

目的探讨抗青光眼术后白内障行晶状体超声乳化吸出术的手术技巧,并评价手术效果。方法对26例（32眼）青光眼术后的白内障行颠侧透明角膜切口晶状体超声乳化吸出折叠人工晶状体植入术,术后随访4～21个月,观察视力、滤过泡、眼压和并发症的情况。结果有30眼（93．75％）视力有不同程度的提高;2眼术后视力无提高者系青光眼性视神经萎缩者。术后矫正视力低于0．05者3眼（9．38％）,0．3～1．0者21眼（65．63％）．所有病例术后滤过泡均无影响,术后眼压在正常范围。结论青光眼术后白内障采用颞侧透明角膜切口行晶状体超声乳化吸出,折叠人工晶状体植入术效果良好,并发症少,可提高视力并保持滤过泡的功能。     

超声乳化白内障吸除人工晶体植入联合小梁切除术的临床应用

目的：观察超声乳化白内障吸除人工晶状体植入联合小梁切除术的临床效果。方法：对开角型或慢性闭角型青光眼合并白内障患者30例(40只眼)，行超声乳化白内障吸除人工晶体植入联合小梁切除术，主要观察术后滤泡的形成，视力、眼压和并发症的发生情况。术后随访时间6个月。结果：30例(40只眼)术后6个月平均眼压控制10mmHg～21mmHg。视力均有不同程度提高0．05～0．5，滤泡Ⅰ、Ⅱ型功能性滤过泡35只。术后无严重并发症发生。结论：超声乳化白内障吸除人工晶体植入联合小梁切除术安全、有效、便捷，近期疗效好。     

白内障超声乳化人工晶体植入联合小梁切除术的临床观察

目的：探讨白内障超声乳化人工晶体植入联合小梁切除术治疗急性闭角型青光眼合并白内障的疗效。方法：对35例急性闭角型青光眼合并白内障的患者施行白内障超声乳化人工晶体植入联合小梁切除术,术后随访1~12个月,观察患者角膜、眼压、滤过泡以及并发症的情况。结果：术后随访观察眼压平均为（14.3±4.25）mmHg,有3例眼压高于正常。滤过泡：Ⅰ型滤过泡18眼,Ⅱ型滤过泡13眼,Ⅲ型滤过泡4眼。并发症有15例术后前房内有渗出物,药物治疗后全部吸收;术后前3d角膜水肿有25例,经治疗后水肿全部消退,无角膜失代偿,无浅前房发生,无后囊膜破裂。结论：白内障超声乳化人工晶体植入联合小梁切除术治疗急性闭角型青光眼合并白内障是一种安全有效的方法,且并发症少。     

两种不同手术方式治疗青光眼合并白内障的对比分析

目的:观察透明角膜切口白内障超声乳化人工晶体植入联合小梁切除术(以下简称白内障超声乳化三联术)和巩膜隧道切口白内障超声乳化人工晶体植入联合小梁切除术治疗青光眼合并白内障的临床疗效差异.方法:对年龄45～70岁,平均年龄58.7岁的青光眼合并白内障患者分两组,A组46例(51只眼),行透明角膜切口白内障超声乳化三联术;B组45例(47只眼)行巩膜隧道切口白内障超声乳化三联术.分析两种不同术式白内障超声乳化三联术的临床疗效.结果:两组术后视力、眼压无显著性差异,功能性滤泡形成率存在差别.术后并发症有角膜内皮水肿、前房轻度至中度前葡萄膜反应等.结论:透明角膜切口白内障超声乳化三联术与巩膜隧道切口白内障超声乳化三联术治疗青光眼合并白内障疗效比较,前者不但术后视力恢复迅速,能良好的控制眼压,功能性滤过泡形成显著,并发症少,而且在青光眼并存白内障情况下采用透明角膜切口超声乳化三联术是安全、有效、可靠的治疗方法.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.