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1.
患者,男,29岁。因腰骶部疼痛、感觉腰背僵硬10余年。乏力、心悸、气促反复发作8年,加重1天,于1989年2月13日入院。既往体健。查体:T 36.5℃,BP 16.0/8.0 KPa(120/60 mmHg),消瘦貌、结膜、颜面略苍白,全身皮肤粘膜未见异常。颈部可见明显动脉搏动。  相似文献   

2.
皮肌炎合并乳癌1例徐平,贾振庚(普外科)患者女性32岁病案号5842721a前无明显诱因出现面部、眼睑淡紫色水肿,同时出现毛细血管扩张性红斑,眼睑境界不清,眼眶周围有压痛,皮损逐渐向颈、胸、肩及四肢皮肤扩展,并互相融合,皮肤发硬,伴有低热及肌痛、无力...  相似文献   

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患男,71岁,因进行性腰部活动受限50年,间断胸闷、气短2年,加重2月入院.50年前无明显诱因出现腰骶部疼痛,伴晨僵,并出现进行性腰椎活动受限,驼背畸形,于当地医院诊为"强直性脊柱炎",未予正规治疗.  相似文献   

5.
患者32岁,女性,1年前无明显诱因出现面部眼睑淡紫色水肿,同时出现毛细血管扩张性红斑,尤以眼睑境界不清,眼眶周围有压痛,皮损逐渐向颈、胸、肩及四肢扩展并互相融合,有时皮肤发硬,伴有低热及肌痛无力,在当地医院诊断为“皮肌炎”。长  相似文献   

6.
皮肌炎是比较少见的结缔组织病,近年来结缔组织病合并恶性肿瘤已有报道现将在门诊遇到一例报告如下: 患者,男性,53岁。门诊号47872。该患以双眼睑暗红、肿胀,周身无力伴疼痛三个月就诊。今年三月初,患者感冒发烧、咳嗽,在当地医院治疗,口服复方新诺明,去痛片、病毒灵各2片,每日三次。一周后病情好转,  相似文献   

7.
患者男,48岁;因乏力、发热、皮疹4个月,进行性胸闷、憋气2个月,于2005年6月15日入院.患者于2005年2月出现乏力,无明显肌痛、肌无力,伴发热(最高体温39℃),双手诸关节、双腕关节、双踝关节肿痛,并出现眼眶周围紫红色充血性皮疹,双手近端指间关节、肘关节、膝关节伸侧可见淡红色鳞屑皮疹,鼻梁、双耳廓、双上肢近端及双侧肩胛区皮肤破溃,有明显血管炎的表现,反复口腔溃疡.4月中旬出现胸闷、憋气,间断咳嗽、咳少许白黏痰;肺CT示双肺间质性肺炎,双侧胸膜增厚.  相似文献   

8.
败血症是儿科常见的重症感染性疾病,容易合并多系统脏器的损害,现将我院收治的败血症合并心脏损害59例,报告如下:1 临床资料1.1 一般资料:男41例,女18例,新生儿5例,1~3岁28例,4~7岁19例,8~14岁7例。转归:治愈48例,好转5例,死亡7例,病死率11.8%。  相似文献   

9.
Dermatomyositis (DM) is an autoimmune disease characterized by muscle involvement of the proximal extremities and specific skin involvement, like Gottron sign and heliotrope rash. Henoch-Schonlein purpura (IgA vasculitis) nephritis is characterized by hematuria and/or proteinuria clinically, with histologic evidence of IgA nephropathy, and also can be clinically characterized by non-thrombocytopenic purpura, presenting with petechiae and ecchymosis on the skin and mucous membranes, often involving multiple organs and systems, accompanied by abdominal pain, joint swelling and pain, and renal lesions. We reported here a patient with symmetric muscle weakness in her proximal limbs and typical Gottron sign, whose laboratory examination showed elevated creatine kinase (CK) level and myogenic damage electromyographically, which were concomitant with dermatomyositis. We applied prednisone combined with cyclophosphamide, and the patient’s muscle strength;, interstitial lung disease and all improved gradually. The patient gradually developed severe hepatic damage [significantly increased glutamic-pyruvic transaminase (ALT), glutamic oxalacetic transaminase (AST) and bilirubin], high fever (body temperature fluctuated between 38.0-39.2 ℃), thrombocytopenia (limb distal purplish rash, some slightly protruded from the skin surface, some fused into a piece, which did not fade with pressure) and intractable diarrhea (water-like stool, antidiarrheal drug treatment was not good), with new onset of the skin lesions on multiple areas of her body, as well as abrupt occurrence of massive proteinuria, which resulted in huge challenges in the following diagnosis and treatment. After extensive differential diagnosis from various directions, including pathological biopsies, it finally came out to be dermatomyositis combined with IgA vasculitis, which had been rarely reported. Both cell-mediated immunity to muscle antigens and immune-complex disease might participate in the pathogenesis. There was evidence that they were immune complex diseases. Several immune mechanisms played an important role in the pathogenesis of both DM and IgA vasculitis. We conducted a substantial literature review of the above diseases. The purpose of our study is to strengthen the clinical understanding of such complicated diseases, and to highlight the importance of pathological biopsy in the diagnosis (renal biopsy pathology gave us a definite diagnosis). And what is more important is that seizing the opportunity to initiate treatment can control the disease and improve the prognosis.  相似文献   

10.
患者女性 ,6 5岁 ,因面部、躯干、四肢弥漫性紫红斑 1年余 ,肌痛、肌无力 6月入院。于 1年前出现面部、躯干、四肢弥漫性紫红斑 ,在院外诊断为“湿疹” ,给予抗过敏治疗 ,皮疹无好转且逐渐增多。入院前 6月 ,患者感肌肉酸痛 ,肌无力 ,双手掌及肘关节处皮肤出现红斑 ,自觉瘙痒剧  相似文献   

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银屑病是一种慢性复发性炎症性皮肤病,该病特征表现为鳞屑性红斑、丘疹,其病因可能与遗传、免疫、环境因素相关。皮肌炎是一种以红斑、水肿为皮损特点,伴有肌肉炎症及变性的疾病,其发病与自身免疫异常或恶性肿瘤等有关,两病并发极少见,本例患者两病并发,报告如下。  相似文献   

13.
皮肌炎(dermatomyositis,DM)是一种特发性炎症性肌病,以慢性近端骨骼肌无力、独特的皮肤损害为特征.皮肌炎合并食管黏膜剥脱临床上少见.1例36岁男性患者因"四肢肌肉酸痛、吞咽困难及咽痛"入院,被诊断为DM合并食管黏膜剥脱.患者经过糖皮质激素、免疫抑制剂、针灸及内镜黏膜下剥离术(endoscopic sub...  相似文献   

14.
皮肌炎属自身免疫性结缔组织疾病之一,是一种主要累及横纹肌,呈以淋巴细胞浸润为主的非化脓性炎症病变,可伴有或不伴有多种皮肤损害,也可伴发各种内脏损害。治疗以激素及免疫抑制剂为主。1病案举例患者,女,48岁。因肌肉关节乏力、疼痛7年,伴咳嗽、咯痰,烦躁两月余入院。患者7年前确诊为皮肌炎,坚持服用雷公藤多苷片、激素、氨甲蹀令等药,效可。入院前2个月无明显诱因出现咳嗽、咯痰,  相似文献   

15.
皮肌炎和多肌炎病人血清中可检出抗氨基酸-tRNA合成酶等多种"肌炎特异性自身抗体",并发现抗体阳性病人常出现间质性肺炎、关节炎和雷诺现象等合并症,称之为抗合成酶综合征.本文报道皮肌炎合并抗合成酶综合征1例.  相似文献   

16.
过敏性紫癜是一种以全身毛细血管炎为主要病变的变态反应性疾病,病理改变较为广泛,涉及多个脏器和系统,但累及心脏较为少见。现将1999年1月-2007年1月我科收治的134例过敏性紫癜中,12例并发心脏损害,现报告如下。  相似文献   

17.
皮肌炎是以皮肤红斑、水肿为临床特征,同时伴有肌无力、肌肉炎症或变性,以及关节和心肌等多器官损害的一种自身免疫性微血管病。原发性输卵管癌是非常少见的恶性肿瘤,占女性生殖系统恶性肿瘤的0.1%-1.8%[1]。皮肌炎伴发恶性肿瘤早已有报道,随着年龄的增大,伴发肿瘤的概率增高,但皮肌炎合并原发性输卵管癌的病例还是比较少见,现报道1例。  相似文献   

18.
皮肌炎为一种病因不明的结缔组织病,较易合并恶性肿瘤,但合并上颌窦癌罕见。我们遇见1例,现报告如下。  相似文献   

19.
皮肌炎合并胃癌及肝转移1例一院皮肤科检验科周毅成张岩任梅患者,男,53岁。1988年4月初,无何明显诱因颜面、躯干及四肢突然出现大片红斑,在红斑基础上起粟粒大小水疱,颜面肿胀,伴周身乏力,双上肢抬举困难。门诊以皮肌炎收入院。查体:一般状况尚可,心肺未...  相似文献   

20.
<正> 患者男,60岁。主诉头昏3年,全身疼痛、心慌2月余。曾测血压力25.33/11.99kPa,2月前因感冒出现全身肌痛,以三角肌、腓肠肌为著,无力,多汗,心慌,眼睑浮肿。既往体健。查体:脉博120次/min,血压22.66/11.99kPa,  相似文献   

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