Oncolytic viral therapy for cancer therapy

Recently, tumor-selective replicating viruses offer appealing advantages over conventional cancer therapy and are a promising new approach for the human cancer therapy. The development of oncolytic viral therapeutics is based on various strategies that each provides a different foundation for tumor-selective targeting and replication. Results from clinical trials of oncolytic viral therapy demonstrate the safety and feasibility of a new approach for cancer. Strategies to overcome various obstacles and challenges to this therapy are currently being searched. In the future, the development of oncolytic viral therapies will extend the range of tumors that can be treated using this novel treatment modality. In this paper, I would like to summarize the advances in the field including the findings from the viral treatment that we are currently utilizing.     

Gene therapy for cancer: bacteria-mediated anti-angiogenesis therapy

Several bacterial species have inherent ability to colonize solid tumors in vivo. However, their natural anti-tumor activity can be enhanced by genetic engineering that enables these bacteria express or transfer therapeutic molecules into target cells. In this review, we summarize latest research on cancer therapy using genetically modified bacteria with particular emphasis on blocking tumor angiogenesis. Despite recent progress, only a few recent studies on bacterial tumor therapy have focused on anti-angiogenesis. Bacteria-mediated anti-angiogenesis therapy for cancer, however, is an attractive approach given that solid tumors are often characterized by increased vascularization. Here, we discuss four different approaches for using modified bacteria as anti-cancer therapeutics--bactofection, DNA vaccination, alternative gene therapy and transkingdom RNA interference--with a specific focus on angiogenesis suppression. Critical areas and future directions for this field are also outlined.     

针灸疗法与康复医学的运动疗法

针灸疗法与康复医学的运动疗法在临床上的协同运用,集中体现在对脑卒中偏瘫的治疗上,具体选择具有治疗作用的针刺体位,对“独取阳明”传统取穴理论的修正。软瘫期刺激涌泉,强刺激优势肌群（上肢阴经、下肢阳经所在）,泻患侧补健侧;痉挛期兴奋非优势肌群（上肢阳经、下肢阴经所在）等,同时涉及对疗效评价的重新认识。     

Body-image therapy

Body image is a complex interplay of factors resulting in a sense of the body perceived by that individual. In eating-disorder clients, there is a distortion between their perceived image of their body and its actuality. This is combined with a sense of dissatisfaction and alienation of mind and body. Cognitive, right-brain, and kinesthetic strategies are described that seek to decrease distortion and dissatisfaction and facilitates individuation-separation and a reintegration of the self. These strategies are both therapeutic and evaluative. Cultural expectations of women have had a profound impact on the proliferation of eating disorders, and they account for the fact that body distortion is found in both normal and eating-disordered women.     

Movement therapy

Nursing's holistic approach to patient care requires that nurses use interventions that promote holism. Movement therapy is one of a number of possible holistic interventions neuroscience nurses can use. This intervention helps persons to become aware of their bodies and to use the body for expressing inner feelings. Two techniques, creative dance and afspaending, are described along with suggestions for their use with neuroscience populations.