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1.
QuantitativeAnalysisoftheTomographicTechnetium-99mMIBI(~(99m)Tc-MIBI)MyocardialBullseyeDisplay:ApplicationtoDiagnosisofCorona?..  相似文献   

2.
Vasoactive effects of adrenotensin and its interactions with adrenomedullin   总被引:4,自引:0,他引:4  
Proadrenomedullin (Pro ADM)isaprecursorencodedbytheadrenomedullingene Therearetypicallythreepairedbasicaminoacids ,whichrepresentsitesforproteolyticprocessingsignalinPro ADM ProteolyticcleavagesofPro ADMatthreesitesreleasefourpeptides :Pro ADM2 2 4 1(prodepino…  相似文献   

3.
INTRODUCTIONDisabilityAdjustedLifeYear(DALY)isanewmeasurementofburdenofdisease(BOD)introducedbyC.Murrayandhiscolleagues(Murray,1994;MurrayandLopez,1994).ThismeasurementconsistsofYearsofLifeLost(YLL)andYearsLivedwithDisability(YLD).DALYismorereasonableandcomprehe…  相似文献   

4.
Thesteroidhormone 1,2 5 dihydroxyvitaminD3 (1,2 5(OH) 2 D3 )isbiologicallythemostactiveformofvitaminD3 andplaysanimportantroleintheregulationofcalciumandbonemetabolism Theeffectsof1,2 5(OH) 2 D3 aremediatedbyvitaminDreceptors (VDR)intargettissues Inthelastdecade,VDRwasno…  相似文献   

5.
Alveolarechinococcosis (AE )ofliverassociatedwithsimultaneouslungandbrainmetastasesisrareclinically Duringaperiodof 15years (1985 - 2 0 0 0 ) ,2 (1 9% )of10 3caseswithliverAEdiagnosedatourlaboratorywereassociatedwithsimultaneouslungorbrainmetastases 1 Theywereconfirmedpa…  相似文献   

6.
Alzheimer sdisease (AD) ,aprogressiveneurodegenerativedisorder,ischaracterizedneu ropathologicallybyneuroticplaque ,neurofibril larytangles,andselectiveneuronalloss[1] .Neu ronalapoptosisisthecausativefactorofneuronslossandneuropathogenesisinAD .Caspasesareres…  相似文献   

7.
SurgicalTreatmentofAscendingAorticDissectingAneurysm-ClinicalApplicationofModifiedCabrol'sOperationYANGChenyuan(杨辰垣),LANHongj...  相似文献   

8.
Dilatedcardiomyopathy(DCM)andischemiccardiomyopathy(CADCM)mayhavesimilarclinicalpresentations,suchascardiomegaly,impairedleftventricularfunctionandcongestiveheartfailureThedifferentiationofDCMfromCADCMsometimesisdifficultbutimportant,sinceprognosisandtr…  相似文献   

9.
Theriskofosteoporosisiscloselyrelatedtobonemineraldensity (BMD ) ,whichisunderstronggeneticcontrol Morrisonetal1 haveshownastrongrelationshipbetweenpolymorphismatthevitaminDreceptor (VDR)geneandBMD InadditiontoBsmⅠ ,restrictionfragmentlengthpolymorphismatth…  相似文献   

10.
INTRODUCTIONSulphurmustard [bis( 2 chloroethyl)sulfide] (SM) ,abifunctionalalkylatingagent,ishighlyreactivewithnucleophilicmoleculessuchasDNAandproteins.Thismayaffectcellularmetabolism ,includingmutagenesis,cytotoxicityandvesication (Papirmeisteretal.,1 991 ) .Howe…  相似文献   

11.
ObjectiveTostudythemolecularmechanismsofdrugresistanceinMycobacterium(M)tuberculosis,toevaluatethevalueoftheβsubunitofRNApol...  相似文献   

12.
Accumulationofpairedhelicalfilaments (PHFs)inspecificneuronsisoneofthehistopathologicalhallmarksoftheAlzheimer’sdiseased (AD )brainandthemicrotubuleassociatedprotein (MAP) ,Tau ,isthemajorproteinofPHFs 1,2  ThebiologicalactivityofTauisregulatedbyitsdegreeofph…  相似文献   

13.
INTRODUCTION  CD9antigen(Ag)isa 2 4 kDmembraneglycoproteinexpressedonthesurfaceofhumanplateletsaswellasonthesurfaceoflymphoidprogenitorcells ,pre Bcellleukemiaandothercelltypes.Thisproteinbelongstoarecentlydelin eatedfamilyofcell surfaceAgsthatspanthemembra…  相似文献   

14.
Conventionalintra arterialdigitalsubtractionangiography (DSA)usedtoberegardedasthegoldstandardfordiagnosisofintracranialarteriovenousmalformations(AVMs) Recently ,newtechniquesofneuroimagingandcomputerassistedthree dimensionalreconstructionmakeitpossible…  相似文献   

15.
Diabeticnephropathy (DN)isoneofthecommoncomplicationsinmicrovesselsofdia betesmellitus (DM ) .Atpresentthereisnoidealtherapytocureit.  相似文献   

16.
INTRODUCTION  Graves’disease(GD)isoneoftheautoimmunethyroiddiseases(AITD) ,andischaracterizedbyhypermetabolicandhyperthyroidsyndromecausedbyTSHreceptor stimulatingantibody TheetiologyandpathogenesisofGDarestillnotfullyclarified TheroleofTcellswaswidelyst…  相似文献   

17.
目的 研究维生素D3(VD3)、9-顺式维甲酸(9-sic-RA)及其相应核受体对hsp90β基因表达的调控作用。方法 采用DEAE-Dextran方法将人hsp90β基因调控片段(-1 039 bp/+1 531 bp)介导的荧光素酶(Luc)报告基因质粒β1.11转染Jurkat细胞,并用VD3和9-cis-RA分别或同时刺激细胞,或将质粒β1.11及野生型维生素D3受体(VDR)或/和维甲酸  相似文献   

18.
Lipoproteinlipase (LPL)isoneofthekeyenzymesinthecourseoflipidandlipoproteinmetabolism[1] .Itprovidesfreefattyacidsforenergytotissuesbycatalyzingthehydrolysisoftriglyceride (TG )inthecoreofchylomicron(CM )andverylowdensitylipoprotein(VLDL) ,andpromotesthetrans…  相似文献   

19.
ethods LowdensitylipoproteinwasisolatedfromnormalheparinizedbloodbydensitygradientultracentrifugationandoxidizedbyCuCl2 TotalRNAwasextractedfromhumanumbilicalveinendothelialcells (HUVECs)exposedtoLDLorOX LDL ,usingtheguanidiniumisothiocyanatemethod Thequ…  相似文献   

20.
Polymorphisms of TAP, LMP and HLA-DM genes in the Chinese   总被引:1,自引:0,他引:1  
Transporterassociatedwithantigenprocessing(TAP),lowmolecularweightproteasome(LMP)andHLADMareMHCclassⅡlikegeneswhichhavebeenmappedbetweenHLADPandHLADOlociintheclassⅡregionofthehumanmajorhistocompatibilitycomplex1 ThesegenesdifferfromtheclassicclassⅡgenes…  相似文献   

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