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1.
QuantitativeAnalysisoftheTomographicTechnetium-99mMIBI(~(99m)Tc-MIBI)MyocardialBullseyeDisplay:ApplicationtoDiagnosisofCorona?.. 相似文献
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Proadrenomedullin (Pro ADM)isaprecursorencodedbytheadrenomedullingene Therearetypicallythreepairedbasicaminoacids ,whichrepresentsitesforproteolyticprocessingsignalinPro ADM ProteolyticcleavagesofPro ADMatthreesitesreleasefourpeptides :Pro ADM2 2 4 1(prodepino… 相似文献
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INTRODUCTIONDisabilityAdjustedLifeYear(DALY)isanewmeasurementofburdenofdisease(BOD)introducedbyC.Murrayandhiscolleagues(Murray,1994;MurrayandLopez,1994).ThismeasurementconsistsofYearsofLifeLost(YLL)andYearsLivedwithDisability(YLD).DALYismorereasonableandcomprehe… 相似文献
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Effect of 1,25(OH)_2D_3 on the growth and apoptosis of breast cancer cell line MCF-7 总被引:1,自引:0,他引:1
Thesteroidhormone 1,2 5 dihydroxyvitaminD3 (1,2 5(OH) 2 D3 )isbiologicallythemostactiveformofvitaminD3 andplaysanimportantroleintheregulationofcalciumandbonemetabolism Theeffectsof1,2 5(OH) 2 D3 aremediatedbyvitaminDreceptors (VDR)intargettissues Inthelastdecade,VDRwasno… 相似文献
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Two cases of liver alveolar echinococcosis associated with simultaneous lung and brain metastases 总被引:2,自引:1,他引:1
蒋次鹏 《中华医学杂志(英文版)》2002,115(12):1898-1901
Alveolarechinococcosis (AE )ofliverassociatedwithsimultaneouslungandbrainmetastasesisrareclinically Duringaperiodof 15years (1985 - 2 0 0 0 ) ,2 (1 9% )of10 3caseswithliverAEdiagnosedatourlaboratorywereassociatedwithsimultaneouslungorbrainmetastases 1 Theywereconfirmedpa… 相似文献
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A Novel Antisense Oligodeoxynucleotide Targeting Caspase-3 mRNA Prevents PC-12 Cell Apoptosis Induced by Aβ_(25-35) 总被引:1,自引:0,他引:1
Alzheimer sdisease (AD) ,aprogressiveneurodegenerativedisorder,ischaracterizedneu ropathologicallybyneuroticplaque ,neurofibril larytangles,andselectiveneuronalloss[1] .Neu ronalapoptosisisthecausativefactorofneuronslossandneuropathogenesisinAD .Caspasesareres… 相似文献
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SurgicalTreatmentofAscendingAorticDissectingAneurysm-ClinicalApplicationofModifiedCabrol'sOperationYANGChenyuan(杨辰垣),LANHongj... 相似文献
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Dilatedcardiomyopathy(DCM)andischemiccardiomyopathy(CADCM)mayhavesimilarclinicalpresentations,suchascardiomegaly,impairedleftventricularfunctionandcongestiveheartfailureThedifferentiationofDCMfromCADCMsometimesisdifficultbutimportant,sinceprognosisandtr… 相似文献
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Vitamin D receptor gene polymorphism in postmenopausal women of the Han and Uygur nationalities in China 总被引:2,自引:0,他引:2
Theriskofosteoporosisiscloselyrelatedtobonemineraldensity (BMD ) ,whichisunderstronggeneticcontrol Morrisonetal1 haveshownastrongrelationshipbetweenpolymorphismatthevitaminDreceptor (VDR)geneandBMD InadditiontoBsmⅠ ,restrictionfragmentlengthpolymorphismatth… 相似文献
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INTRODUCTIONSulphurmustard [bis( 2 chloroethyl)sulfide] (SM) ,abifunctionalalkylatingagent,ishighlyreactivewithnucleophilicmoleculessuchasDNAandproteins.Thismayaffectcellularmetabolism ,includingmutagenesis,cytotoxicityandvesication (Papirmeisteretal.,1 991 ) .Howe… 相似文献
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Molecular mechanisms of drug resistance in Mycobacterium tuberculosis clinical isolates 总被引:6,自引:0,他引:6
ObjectiveTostudythemolecularmechanismsofdrugresistanceinMycobacterium(M)tuberculosis,toevaluatethevalueoftheβsubunitofRNApol... 相似文献
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海马注射缓缴肽或环胞菌素A导致大鼠行为异常及Alzheimer样Tau蛋白异常磷酸化 总被引:4,自引:1,他引:3
Accumulationofpairedhelicalfilaments (PHFs)inspecificneuronsisoneofthehistopathologicalhallmarksoftheAlzheimer’sdiseased (AD )brainandthemicrotubuleassociatedprotein (MAP) ,Tau ,isthemajorproteinofPHFs 1,2 ThebiologicalactivityofTauisregulatedbyitsdegreeofph… 相似文献
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INTRODUCTION CD9antigen(Ag)isa 2 4 kDmembraneglycoproteinexpressedonthesurfaceofhumanplateletsaswellasonthesurfaceoflymphoidprogenitorcells ,pre Bcellleukemiaandothercelltypes.Thisproteinbelongstoarecentlydelin eatedfamilyofcell surfaceAgsthatspanthemembra… 相似文献
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Noninvasive three-dimensional computed tomographic angiography in preoperative detection of intracranial arteriovenous malformations 总被引:5,自引:0,他引:5
Conventionalintra arterialdigitalsubtractionangiography (DSA)usedtoberegardedasthegoldstandardfordiagnosisofintracranialarteriovenousmalformations(AVMs) Recently ,newtechniquesofneuroimagingandcomputerassistedthree dimensionalreconstructionmakeitpossible… 相似文献
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INTRODUCTION Graves’disease(GD)isoneoftheautoimmunethyroiddiseases(AITD) ,andischaracterizedbyhypermetabolicandhyperthyroidsyndromecausedbyTSHreceptor stimulatingantibody TheetiologyandpathogenesisofGDarestillnotfullyclarified TheroleofTcellswaswidelyst… 相似文献
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目的 研究维生素D3(VD3)、9-顺式维甲酸(9-sic-RA)及其相应核受体对hsp90β基因表达的调控作用。方法 采用DEAE-Dextran方法将人hsp90β基因调控片段(-1 039 bp/+1 531 bp)介导的荧光素酶(Luc)报告基因质粒β1.11转染Jurkat细胞,并用VD3和9-cis-RA分别或同时刺激细胞,或将质粒β1.11及野生型维生素D3受体(VDR)或/和维甲酸 相似文献
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Lipoproteinlipase (LPL)isoneofthekeyenzymesinthecourseoflipidandlipoproteinmetabolism[1] .Itprovidesfreefattyacidsforenergytotissuesbycatalyzingthehydrolysisoftriglyceride (TG )inthecoreofchylomicron(CM )andverylowdensitylipoprotein(VLDL) ,andpromotesthetrans… 相似文献
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Oxidized low density lipoprotein inhibited tissue factor pathway inhibitor mRNA expression in human endothelial cells 总被引:1,自引:0,他引:1
ethods LowdensitylipoproteinwasisolatedfromnormalheparinizedbloodbydensitygradientultracentrifugationandoxidizedbyCuCl2 TotalRNAwasextractedfromhumanumbilicalveinendothelialcells (HUVECs)exposedtoLDLorOX LDL ,usingtheguanidiniumisothiocyanatemethod Thequ… 相似文献
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Polymorphisms of TAP, LMP and HLA-DM genes in the Chinese 总被引:1,自引:0,他引:1
Transporterassociatedwithantigenprocessing(TAP),lowmolecularweightproteasome(LMP)andHLADMareMHCclassⅡlikegeneswhichhavebeenmappedbetweenHLADPandHLADOlociintheclassⅡregionofthehumanmajorhistocompatibilitycomplex1 ThesegenesdifferfromtheclassicclassⅡgenes… 相似文献