消毒供应中心人员的培训

消毒供应中心是医院各种无菌物品的供应单位.伴随2009版行业标准下发及手术器械集中管理,消毒供应中心真正实行了对全院可复用物品的全流程处理工作.这些器械上沾染着大量的不可知细菌与病毒,或由于少数工作人员缺乏职业道德和工作责任心,未严格执行操作规程而使物品存在未清洗净、重复污染和包装不合格等风险[1].     

医院外科病房开水瓶塞污染的调查及对策

目的调查了解普通外科、泌尿外科病房开水瓶塞的细菌污染情况及对消毒效果进行分析,为预防院内感染提供相应的对策。方法在无菌操作下取开水瓶塞用沾有无菌洗脱液的棉拭子反复涂擦采样,剪开操纵者手接触部分,将棉拭子投入5ml无菌洗脱液中,立即送检。结果通过对120个开水瓶塞在外科病房使用后进行消毒前和消毒后细菌培养分析,发现未消毒的开水瓶塞有大量条件致病菌存在,消毒后的开水瓶塞细菌数明显减少。结论开水瓶塞的污染已成为院内潜在的感染源。对开水瓶塞使用后进行有规范的消毒处理,对预防院内感染有着重要的意义。     

对供应室下送车辆消毒方法的探讨

供应室下送车辆是每日用来下送无菌物品到临床各科室的车辆 ,它每日穿梭于供应室与临床各科室之间 ,是地面的污染源和细菌传播的载体之一 ,也是污染无菌物品导致院内交叉感染的因素之一。因此 ,对下送车辆的消毒处理是不可忽视的 ,现将对供应室下送车辆消毒方法报告如下。1　材料下送车辆、佳顺消毒液、紫外线灯、无菌试管、棉拭子、5 cm× 5 cm无菌规格板 ,无菌生理盐水 ,普通营养琼脂平板。2　方法采用三种方法对下送车辆进行消毒灭菌 ,标本为下送后未经消毒的下送车辆 ,三种采样的方法不交叉 ,每种方法消毒后各作 15例对照固定消毒前后采…     

使用中消毒剂与无菌器械保存液污染情况调查

为了解我市医疗单位使用中消毒剂与无菌器械保存液细菌污染情况,查明存在的问题及原因,探讨消毒质量控制工作重点,我们于1999年5～10月,对全市38家城乡医院(即城区与     

勃利县托幼机构2007～2008年细菌污染调查结果分析

目的了解我县托幼机构2007～2008年空气、物品细菌污染情况,为指导托幼机构消毒工作提供参考。方法采样方法和检验步骤按国家规范或标准,全部样品均在无菌实验室内进行检测。结果两年物体表面细菌指标平均合格率为65.6%,空气细菌指标平均合格率为54.1%,水杯污染最为严重。结论托幼机构负责人要从思想上高度重视消毒工作,完善各种消毒设施,使消毒工作经常化、制度化。     

供应室无菌间存在的问题及对策

针对供应室无菌间工作存在的问题。提出要控制造成无菌物品再次污染及无菌物品不符合要求。必须做好环境管理,严格执行隔离消毒制度及无菌技术操作,加强工作人员责任心、事业心。杜绝不符合无菌物品要求或再次污染的无菌物品流入无菌间。从而才能保证供应室所提供无菌物品质量达到符合要求,临床使用满意。     

童丘市医科机构消毒监测结果分析

为了认真贯彻落实卫生部颁发的《消毒管理办法》,提高医疗机构消毒质量 ,控制医源感染 ,保障人民健康 ,我站于 2 0 0 1年7～ 1 0月对本市 1 2 2个医疗单位的医疗用具进行了消毒效果监测。现将监测结果报告如下 :1　材料与方法1 .1　监测对象　 4所市级医院 ,1 5所乡镇卫生院 ,2 5所厂企卫生所 ,78所村保健所和个体诊所的医疗用具 (无菌针头、针管、持物钳 )及空气细菌。1 .2　检验方法　统一按 1 991年 1 2月卫生部颁发的《消毒技术规范》进行 ,空气细菌检测用平板沉降法。1 .3　标准　灭菌针头、注射器以无菌生长为合格 ,物体表面的细菌菌…     

过氧化氢熏蒸消毒手术物品的效果观察

本文报道使用过氧化氢熏蒸消毒法用于手术物品的消毒效果。选择电刀导线、尿管、剪刀及橡胶管作为试验对象,将以上物品放于自制的消毒箱内,将过氧化氢加热挥发,封闭消毒箱2h,以上物品消毒前后分别在无菌技术下用同样的方法采集标本,进行细菌培养。结果：消毒后全部无细菌生长,合格率达100%。文章认为,过氧化氢主要是由于加热后挥发释放出新生态氧,破坏细菌酶的结构,致使细菌代谢发生障碍,从而起到杀菌消毒作用。     

采浆室空气消毒机与紫外线灯管空气消毒效果的比较

目的用空气细菌培养结果对肯格王牌YKX/G-120型空气消毒机与传统紫外线灯管空气消毒效果进行比较,以保证采浆室无菌环境和采浆安全。方法两种消毒方法各取20次数据。结果空气消毒机法空气细菌数(53.43±17.34);紫外线灯管空气细菌数(61.50±8.61),两组总细菌数对比无显著性差异(t=1.24,P>0.05)。结论空气消毒机空气消毒效果与紫外线灯管一致。     

检验科静脉采血室消毒措施及感染监测

目的 探讨检验科静脉采血室消毒及感染监测,以防止或降低院内交叉感染发生率。方法 本院感染科制定了一套消毒制度及消毒后的监测,并于消毒前和消毒后分别进行细菌病源学监测。结果 消毒前有病源菌生长,消毒后均无菌生长。结论 实施严格有效的消毒措施可有效防止或降低交叉感染发生率,提高患者住院质量。     

Disruption of tracheobronchial airway growth following postnatal exposure to ozone and ultrafine particles

This study examined airway structure changes in adult rats after a long recovery period due to sub-chronic juvenile exposure to ozone and ultrafine particles that have a high organic fraction. Neonatal male Sprague-Dawley rats were exposed during lung development to 3 cycles of 0.5?ppm ozone from postnatal day 7 through 25. Two different exposure patterns were used: 5-day exposure per week (Ozone52) or 2-day exposure per week (Ozone25) with or without co-exposure to ultrafine particles (OPFP5252, OPFP5225). Airway architecture was evaluated at 81 days of age, after 56 days of continued development beyond the exposure period in filtered air (FA). By analyzing CT images from lung airway casts, we determined airway diameter, length, branching angle, and rotation angle for most conducting airways. Compared with the FA control group, the Ozone52 group showed significant decreases in airway diameter in generations larger than 10 especially in the right diaphragmatic lobe and in airway length in distal generations, while changes in airway structure due to the Ozone25 exposure were not appreciable. Interaction effects of ozone and ultrafine particle exposures were not significant. These results suggest that airway alterations due to postnatal ozone exposure are not limited to the distal region but occur extensively from the middle to distal conducting airways. Further, alterations due to early ozone exposure do not recover nearly 2 months after exposure has ceased demonstrating a persistent airway structural change following an early life exposure to ozone.     

Disruption of tracheobronchial airway growth following postnatal exposure to ozone and ultrafine particles

This study examined airway structure changes in adult rats after a long recovery period due to sub-chronic juvenile exposure to ozone and ultrafine particles that have a high organic fraction. Neonatal male Sprague-Dawley rats were exposed during lung development to 3 cycles of 0.5 ppm ozone from postnatal day 7 through 25. Two different exposure patterns were used: 5-day exposure per week (Ozone52) or 2-day exposure per week (Ozone25) with or without co-exposure to ultrafine particles (OPFP5252, OPFP5225). Airway architecture was evaluated at 81 days of age, after 56 days of continued development beyond the exposure period in filtered air (FA). By analyzing CT images from lung airway casts, we determined airway diameter, length, branching angle, and rotation angle for most conducting airways. Compared with the FA control group, the Ozone52 group showed significant decreases in airway diameter in generations larger than 10 especially in the right diaphragmatic lobe and in airway length in distal generations, while changes in airway structure due to the Ozone25 exposure were not appreciable. Interaction effects of ozone and ultrafine particle exposures were not significant. These results suggest that airway alterations due to postnatal ozone exposure are not limited to the distal region but occur extensively from the middle to distal conducting airways. Further, alterations due to early ozone exposure do not recover nearly 2 months after exposure has ceased demonstrating a persistent airway structural change following an early life exposure to ozone.     

臭氧应用于空调系统消毒

目的：验证臭氧在空调净化系统中的消毒效果，从而取代甲醛熏蒸消毒的传统方法。方法：采用枯草芽孢杆菌作生物指示剂，进行细菌挑战性试验。并将臭氧灭菌与甲醛熏蒸灭菌的操作特点进行了比较。结果：在规定时间内杀死全部枯草孢杆菌。结论：臭氧灭菌完全可以取代甲醛灭菌。     

霉菌性阴道炎的臭氧治疗及护理

目的探讨臭氧用于治疗霉菌性阴道炎患者的疗效及护理。方法 140例霉菌性阴道炎患者,分成观察组和对照组两组。对照组采用洁尔阴;观察组采用臭氧液,并配置合理的护理措施。结果观察组治愈率为85.71%高于对照组治愈率71.43%,差异有统计学意义(P<0.05)。结论采用臭氧液并配置合理的护理措施治疗霉菌性阴道炎患者疗效佳,具有较高的临床应用价值。     

医用臭氧局部注射治疗舌咽神经痛30例疗效观察

目的 观察医用臭氧局部注射治疗舌咽神经痛的临床疗效.方法 将60例舌咽神经痛患者随机分为两组,治疗组行舌咽神经阻滞后注入医用臭氧,再配药物治疗;对照组只行舌咽神经阻滞和药物治疗.结果 治疗组在治疗后7 d、14 d时VAS评分均低于对照组（P＜0.01）;治疗后第14天时治疗组总有效率为86.7%,高于对照组63.3%（P＜0.05）.结论 医用臭氧局部注射治疗舌咽神经痛临床疗效明显,有推广价值.     

臭氧灭菌技术在药厂10万级洁净区的应用研究

目的建立合适的药厂洁净区灭菌方法。方法比较传统灭菌方法和臭氧灭菌之间的优缺点,并检测洁净区臭氧浓度,验证臭氧灭菌效果。结果臭氧灭菌技术可以应用于药厂洁净区灭菌。结论臭氧灭菌技术的广泛应用具有良好前景。     

臭氧配合玻璃酸钠关节内注射治疗膝关节骨性关节炎220例临床观察

目的探讨臭氧配合玻璃酸钠关节内注射治疗膝关节骨性关节炎的临床疗效及治疗机理。方法将220例膝关节骨性关节炎患者随机分为臭氧组和对照组,每组110例。臭氧组采用医用臭氧配合玻璃酸钠关节内注射;对照组采用单纯玻璃酸钠关节内注射。结果臭氧组总有效率为84.5%高于对照组的70.0%,差异有统计学意义（P〈0.05）。结论臭氧配合玻璃酸钠关节内注射是治疗老年退行性膝关节炎较好的方法。     

Study of ground-level ozone and its health risk assessment in residents in Ahvaz City,Iran during 2013

Ozone is a highly oxidative compound and is one of the important pollutants present in the atmosphere and at ground level. Concentration of ground-level ozone (GLO) pollutant depends on different factors such as the amount of VOC and NO_X, heat and location in the atmosphere. Ozone can cause health effects such as problems to breathe deeply and vigorously, inflame and damage the airways, bronchitis, reduced lung function in children and adults, emphysema and increase the frequency of asthma attacks. In this work, we focused on the determination of number of hospital admissions associated with ozone in Ahvaz with population of 1?000?000, during 2013. In this study, ozone data collections were through Iranian Environmental Protection Agency (Iranian EPA) and Meteorological Organization. Ozone data and meteorological parameters were used in Excel software to prepare input file of AirQ model. After running model, outputs presented in term of hospital admissions of ozone exposure were calculated. According to this study, “Havashenasi” and “Naderi” had the lowest and the highest ozone concentrations. Results of this study showed that if ozone concentrations were more than 20?μg/m³, approximately 12% hospital admissions were attributed by this pollutant. The results showed that the concentration of ozone was related to Ahvaz with an annual average of 223?μg/m³. Ozone concentration in Ahvaz was higher than standard. Mitigation measures in industries and transportation system in Ahvaz metropolitan is recommending to reduce the level of ozone in the ambient air. Changing the fuel process and using upgraded vehicles could be possibly very effective to diminish the impact of this pollutants on citizens.     

臭氧液与达克宁栓联合治疗阴道炎的效果分析

目的观察臭氧液与达克宁栓联合治疗阴道炎的临床效果。方法选取2011年7月一2012年7月在本院门诊就诊的160例阴道炎患者,将其随机分为观察组和对照组,观察组80例采用臭氧液与达克宁栓联合治疗,对照组80例仅采用达克宁栓进行治疗,对比两组的临床疗效。结果观察组的治愈率为90．00％,对照组的治愈率为50．00％,观察组高于对照组,差异有统计学意义（P〈O．05）;治疗后观察组外阴阴道瘙痒、灼痛消失时间,阴道分泌物消失时间,阴道糜烂消失时间短于对照组,差异有统计学意义（P〈O．05）;治疗后1个月,对两组治愈的患者再一次进行检查,观察组治愈的患者复发率为4．2％,对照组治愈的患者复发率为20．0％,观察组复发率低于对照组,差异有统计学意义（P〈O．05）。结论臭氧液与达克宁栓联合治疗阴道炎的效果显著,值得临床应用推广。     

Behavioral evaluation of the irritating properties of ozone

The sensory irritant properties of ozone have been considered to be responsible for symptoms that occur in humans after exposure. This assumption has not been studied explicitly. One way to assess the aversive properties of airborne irritants is to give the exposed individual an opportunity to control the duration of exposure, i.e., escape from the irritant. Mice were trained to turn off 1000-ppm ammonia, a concentration that, in humans, is irritating to the upper airways. Each mouse could terminate irritant delivery for 1 min by inserting its nose five times into one of two conical response sensors. Daily exposure was limited to a maximum of twenty-five 1-min exposures, every other minute. After the determination of ammonia concentration-effect curves, ozone was substituted for ammonia. Ozone exposures were alternated every other day with ammonia as a control for any changes that might occur as a result of repeated ozone exposure. Ozone reliably maintained escape behavior. Additional mice with no history of ammonia termination were trained to terminate ozone exposure, indicating that the aversive properties of ozone were not dependent on previous experience with other airborne irritants. As the concentration of ozone increased from 0.25 to 24 ppm, the number of escape responses increased, and the duration of ozone tolerated decreased. Ozone concentrations of 0.5 ppm or greater were significantly more aversive than control.