Treatment of 60 cases of hyperlipidemia by electroacupuncture

Hyperlipidemia, which is the result of lipid metabolic disorder, can be simply divided into 3 types of hypercholesterolemia, hypertriglyceridemia and mixed type in clinic. The increase of lipids in the plasma is the important cause of atherosclerosis. It‘s significant that hyperlipidemia is treated for preventing and treating the cardiovascular and cerebrovascular diseases such as coronary heart disease caused by atherosclerosis. The exploitation of blood-lipid lowering drugs is relatively rapid. But their application is limited in clinic for the side effects and potential fatalness to the elders. The author treated hyperlipidemia by electroacupuncture and it was reported as follows.     

Treatment of 52 cases of lumbar intervertebral disk herniation by acupuncture plus herbal medicine

Lumbar intervertebral disk herniation is a commonly and frequently encountered disease in the orthopedic department, manifested by a series of symptoms such as low back pain, numbness and pain in one or two lower limbs, due to compression to the lumbosacral nerves by protrusion of the pulpiform nucleus after rupture of the fibrous rings. The author has treated 52 cases of this disease by acupuncture plus herbal medicine. Now, the report is given as follows.     

齐刺压痛点以通畅元真治疗肩周炎25例

Triple needling was adopted for treatment of frozen shoulder by the authors, and the report is as follows. CLINICAL DATA All the 25 cases were diagnosed as frozen shoulder by Clinic of TCM, Hubei University of CM during March to October of 2010.There were 10 cases of male and 15 female, with the age ranged from 26 to 54.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type Ⅱ Diabetes

Excess production of reactive oxygen species （ROS） of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes. TCM holds that the damp from the dysfunction of spleen, kidney and liver is the causative factor of complications of diabetes. This is similar to the mechanism of ROS resulting in angiopathic complications of diabetes. When the angiopathic complications of type II diabetes mellitus （T2DM） are differentiated as caused by turbid damp in TCM can be explained as ROS. Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis, the treating principle should be dissolving the damp to remove the obstruction.     

Observation on therapeutic effects of cupping therapy for allergic rhinitis

Allergic rhinitis is mainly characterized by the symptoms of sneezing,tickling sensation in the nose,runny nose,and nasal obstruction,and often occurs after invasion of pathogenic wind and cold.The author has treated 50 cases of this disease by applying cupping therapy on Shenque (CV 8).Now,the report is given as follows.     

FEATURES OF APPLYING CHINESE CHANG-STYLE TAICHI EXERCISES-EXPLORING MECHANISM OF ACUPUNCTURE

Traditional Chinese medicine is extensive and profound with the theory of meridians as its main component part which is also the principle of acupuncture. I wish to introduce the application of the theory of meridian and its integration into Taichi, exploring the mechanism of acupuncture by Qi operation.     

Thinking on functional mechanism of acupuncture for inflammatory bowel diseases based on Metabolomics

Acupuncture has a good therapeutic effect in treatment of inflammatory bowel diseases （IBD）, but its functional mechanism has not been systematically explained. Metabolomics is the scientific study of dynamic chemical processes involving metabolites as well as metabolic response of living organisms. Metabolomics, a research method with integrity and dynamics, corresponds to the overall regulatory effect of acupuncture and is in line with the overall concept of traditional Chinese medicine （TCM） and the concept of homeostasis. In the recent years, metabolomics has been extensively applied to the clinical and experimental study of IBD, and its potential applied value has been unanimously acknowledged by the researchers. In this article, the application status of metabolomics in acupuncture is summarized, and the research ideas to study the mechanism of acupuncture in the regulation and control of IBD by metabolomics are preliminarily explored.     

Research on Meridians in China

The theory of meridian （it is interpreted as channels and collaterals, or meridian in English）, is an important theoretical kernel of traditional Chinese medicine （TCM）. TCM holds that meridian is a complicated system with the fourteen meridians as the main part, which distributes over the whole human body. Each meridian belongs to a corresponding viscus interiorly, and winds around the limbs and joints exteriorly. It functions to transport the qi and blood, regulates the balance between Yin and Yang, responses to the changes in the natural world. It is the pathway for transporting qi and blood. Accordingly, it is considered to be the connective, regulative and responsive system of the body. In comparison to the Western medicine and modem biology, it elucidates the vital process and regulation of the function of human body in a totally different way and involves many brilliant theoretical expositions. Therefore, it has been deeply concerned by many researchers in China and abroad. Once the essence of meridian is elucidated, it must vigorously promote the development of TCM as well as the whole medical science and benefit the mankind.     

A New Compound from Swertia cincta

Objective To study the chemical constituents from the whole plant of Swertia cincta.Methods The chemical constituents were purified by chromatographic methods such as silica gel column and Sephadex LH-20. The structures of these compounds were elucidated by MS, IR, and NMR analyses. Results Two compounds were isolated from S. cincta. Conclusion Compound 1 is a new compound named swercinctlactone A. Compound 2 is identified as(±)-gentiolactone and its configuration is confirmed by single crystal X-ray diffraction and optical specific rotation.     

Dietotherapy for Hyperlipidemia

Hyperlipidemia is a pathological condition in which one or more than one ingredients of plasma lipoprotein is higher than normal in quantity. The primary hyperlipidemia is due to the congenital defect of lipid and lipoprotein metabolism and some environmental factors with unknown causes. And the secondary hyperlipidemia is caused by some diseases, such as diabetes, liver, kidney, and thyroid problems, as well as alcohol drinking, obesity, diet and life style. But no matter in primary or secondary cases, the incidence of hyperlipidemia in senile people is always higher than in people of other ages. In the early stage, there is no obvious symptoms. With the development of pathological condition, the patient will have dizziness, fullness in chest, shortness of breath, and tiredness, and become fat.     

综合疗法治疗膝关节骨关节炎120例

膝关节骨性关节炎是一种临床常见病，笔者应用综合疗法治疗本病，取得满意疗效，现报道如下。     

阳虚质膝骨性关节炎关节软骨中PKC的表达研究

目的:研究阳虚质膝骨性关节炎(Knee Osteoarthritis,KOA)与蛋白激酶C(PKC)表达之间的相关性。方法:从病例调查数据库中随机选取KOA病例共20例,其中非阳虚质KOA患者10例,阳虚质KOA患者10例;非KOA健康志愿者10例作为对照组。采用免疫组化及RT-PCR方法检测PKC在不同组别中的表达。结果:PKC在正常关节软骨及阳虚质KOA与非阳虚质KOA中均有表达,表达主要位于细胞浆及细胞核内,组间进行两两比较,差异有统计学意义(P0.05);PKC基因在对照组与KOA病例组关节软骨组织中的表达进行比较,差异有统计学意义(P0.01);PKC基因在阳虚质病例组、非阳虚质病例组与对照组进行两两比较差异有统计学意义(P0.05)。结论:PKC基因与KOA的发病有一定相关性,且可能与阳虚质高发KOA有一定联系。     

膝骨关节炎肾阳虚动物模型的建立与评价

目的:建立和评价膝骨关节炎(KOA)肾阳虚大鼠模型。方法:24只大鼠随机分成正常组、KOA组、KOA去势组、KOA腺嘌呤组,每组6只。Hulth法建立KOA模型,去势法与腺嘌呤灌胃建立肾阳虚模型。通过Mankin’s和OARSI评分评价KOA模型;通过肾阳虚症状体征评价表及甲状腺轴、性腺轴、肾上腺轴激素水平等评价肾阳虚模型。结果:KOA组、KOA去势组、KOA腺嘌呤组均符合KOA病理表现,OARSI分级分别为2级、3级和4级。与其余3组比较,KOA腺嘌呤组肾阳虚症状体征积分最高(P<0.01,P<0.05),体质量增长最少(P<0.05),肛温最低(P<0.05),T3、T4、FSH、LH、T水平最低(P<0.05),E2水平最高(P<0.05);各组间CORT水平差异无统计学意义。结论:相较于Hulth+去势法,Hulth+腺嘌呤灌胃是构建KOA肾阳虚病证结合模型的更适宜方法。     

补肾活血中药治疗膝骨性关节炎与骨质疏松症“共病”机制研究进展

膝骨性关节炎（knee osteoarthritis,KOA）是一种以膝关节软骨退行性病变和继发性骨质增生为特征的慢性关节疾病。骨质疏松症（osteoporosis,OP）是一种代谢性骨病,主要由于骨量丢失与降低、骨组织微结构破坏、骨脆性增加,导致患者容易出现骨折的全身代谢性骨病。KOA与OP在病因、发病机制方面有很多相似之处,2病病机特点均为以肾虚为本、血瘀为标。通过从促进骨修复、抑制骨破坏2方面对补肾活血类中药治疗KOA与OP“共病”作用机制进行归纳总结,为深入研究KOA与OP“共病”机制提供支持与参考。     

中药三萜类成分防治膝骨关节炎作用机制研究进展

膝骨关节炎（knee osteoarthritis,KOA）是一种严重影响患者生活质量的膝关节功能退行性疾病，目前已成为全球致残率最高的疾病之一。中医药治疗KOA有着悠久的历史和广阔的应用前景，能够有效弥补现代医学治疗KOA的不足。中药三萜类成分对KOA具有良好的防治作用，可通过抑制炎症反应、抗氧化应激反应、抑制软骨细胞凋亡、促进软骨细胞增殖、合成胶原蛋白等延缓KOA的进程，具有多靶点协同性的特点。通过对中药三萜类成分防治KOA的作用机制进行综述，为开发临床治疗KOA的药物提供科学依据。     

灸法治疗膝骨关节炎的研究进展

膝骨关节炎(KOA)是以退行性病理改变为基础,以关节软骨变性和丢失及关节边缘和软骨下骨骨质再生为特征的慢性病、常见病、多发病,男女均可发病。近年来,中医药治疗KOA的研究进入白热化,并取得较大进展,主要的治疗方法有中药内服、中药外用和针灸推拿3大类为主。其中灸法具有温通经络的作用,更成为现如今的研究热点之一。灸法有很多种,对于KOA的治疗研究较多的方法有化脓灸、悬灸、热敏灸、隔物灸、温针灸、灸法结合其他疗法等。对近年来灸法治疗KOA的现状进行简要的综述,并提出存在的问题及未来发展的方向。     

膝骨关节炎患者膝部结筋病灶点与健康受试者筋结点肌骨超声影像学差异研究

目的:运用肌骨超声(MSUS)技术观察膝骨关节炎(KOA)患者结筋病灶点的影像学特征.方法:纳入100例KOA患者与100名健康受试者.按足阳明、足少阳、足太阳、足三阴经筋顺序对KOA患者进行触诊,结合MSUS检查记录患者膝部结筋病灶点及其出现频次.选择出现频次最高的5个结筋病灶点及健康受试者相应部位筋结点作为观察部位...     

推拿治疗膝关节骨性关节炎系统评价的研究进展

膝关节骨性关节炎（KOA）是一种常见病、多发病,推拿手法治疗KOA具有一定的优势。通过检索中国知网数据库近5年来推拿治疗KOA的文献,对推拿手法治疗KOA的系统评价证据进行综述,以了解推拿手法治疗KOA的最新进展,为治疗KOA的方案选择提供新思考。     

数学模型应用于膝关节骨性关节炎证型识别的研究

目的 运用模糊数学方法对膝关节骨性关节炎（KOA）的中医证侯进行客观量化,初步建立该病证型识别的模糊数学模型.方法 依据《中医临床路径实用指南》膝痹病的4个常见证型,参照《中医诊断学》和《中药新药临床研究指导原则》,制定KOA中医辨证要素诊断标准.采用专家评判法,计算出各辨证要素的权重值.以个体模式识别数学模型公式,运用最大隶属度原则建立KOA证型识别数学模型.符合纳入标准的KOA患者分别以人工辨证法和模糊数学识别模型进行辨证.结果 105例病例中两种方法辨证结果一致者90例,辨证符合率为85.71％,一致性经配对卡方检验,Kappa=0.795 （P＜ 0.01）.结论 本研究初步建立了KOA证型识别模糊数学模型,与专家辨证有较高的一致性,经进一步优化有望发展为KOA证型专家诊疗系统.     

基于中医肝肾二脏的膝骨关节炎研究述评

膝骨关节炎(KOA)主因关节滑膜、软骨、细胞外基质和软骨下骨发生损害及病变,导致膝关节活动障碍,甚至畸形.中医认为,KOA属本虚标实之证,肝肾亏虚为本,血瘀筋伤为标.现代研究也表明肝肾功能与KOA有密切关系.本文基于中医肝肾二脏辨治KOA现状进行述评,为中医相关治疗提供借鉴.