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1.
M Taniguchi  K Müller  J Schramm  R R?del 《HNO》1992,40(5):186-192
Hearing preservation was attempted in eight cases of acoustic neurinomas with good preoperative hearing. This was successful in 3 cases. Brain-stem auditory evoked potentials (BAEP0 were monitored in all cases, and compound nerve action potentials (CNAP) were recorded from the cochlear nerve in the last 3 cases. The BAEP was extremely sensitive to intraoperative manipulation. Intraoperative loss of wave V in BAEP was observed not only in all 5 cases with postoperative hearing loss, but also in 2 out of 3 cases with successful hearing preservation. CNAP correlated better with the hearing outcome than BAEP. In the cases where hearing was preserved, intact CNAP responses were demonstrated at the end of the operation. Conversely, deterioration of CNAP was seen in a case of postoperative hearing loss. CNAP was 10-15 times larger in amplitude than BAEP, so that the new responses were obtainable in shorter intervals. This capability of frequent examination seemed to increase the possibility of avoiding irreversible damage to the hearing by changing surgical tactics. The addition of CNAP monitoring is a good supplement to conventional BAEP monitoring in acoustic neurinoma surgery.  相似文献   

2.
OBJECTIVE: Absence of auditory brainstem response (ABR) waveforms has been associated with a poor likelihood of hearing preservation following resection of acoustic neuromas. Our experience is reviewed for patients with absent preoperative ABR regarding hearing preservation, hearing improvement, and return of ABR. STUDY DESIGN: Retrospective review of 22 cases of acoustic neuroma resection. Nine patients with absent preoperative ABR were identified. All underwent tumor resection utilizing intraoperative cochlear nerve action potential (CNAP) monitoring. Postoperative hearing results and ABR waveforms were examined. METHODS: Charts were reviewed and tabulated for age, sex, tumor side, tumor size, preoperative and postoperative audiometric and ABR results, intraoperative monitoring results by ABR and CNAP, and surgical complications. RESULTS: Hearing preservation was achieved in seven of nine patients (78%) with absent preoperative ABR, as well as six of seven patients (86%) with tumors less than or equal to 20 mm in greatest dimension. Although intraoperative ABR monitoring was not possible in any of these patients, CNAP monitoring was successful in all. Return of ABR waveforms was observed in four of the six patients (67%) tested from 3 to 22 months postoperatively. Four of the seven patients (57%) enjoyed improvement in hearing class as defined by the guidelines of the American Academy of Otolaryngology-Head and Neck Surgery. CONCLUSIONS: Absent ABR waveforms have not been a negative prognostic sign regarding hearing preservation. CNAP monitoring is possible in these patients and likely helps to minimize iatrogenic cochlear nerve trauma. Patients with no ABR waveforms have hope of hearing preservation and even improvement following acoustic neuroma resection performed utilizing CNAP monitoring and hearing preservation surgical techniques.  相似文献   

3.
目的探讨听神经瘤术中听力监测的应用及术后听力保留的可能影响因素。方法16例采用乙状窦后入路手术切除听神经瘤的成年患者,分为两组,术中采用听性脑干反应(auditory brainstem response,ABR)和耳蜗电图(electrocochleogram,ECochG)联合监测为监测组(8例),未监测者为未监测组(8例),比较两组患者术后听力保留情况,采用单因素分析,分析影响听力保留的可能因素,包括:年龄、病程、肿瘤大小、术前纯音听阈和言语识别率、术中是否行ABR和ECochG联合监测、内听道是否扩大、肿瘤和神经是否粘连等。结果前庭诱发肌源性电位(VEMP)提示16例患者肿瘤来源于前庭上神经,监测组中6例术中及术毕ABR波Ⅰ、Ⅴ和复合动作电位(CAP)持续存在,术后听力保留;1例术中ABR波Ⅰ、Ⅴ和ECochG CAP持续存在,但术后无可用听力;1例术中切除肿瘤时ECochG与基线重复性良好,ABR波V消失,手术结束波V仍未恢复;监测组术后听力保留率为75.0%(6/8),未监测组术后无一例保留听力,差异有统计学意义(P=0.007)。单因素分析显示,年龄、病程、肿瘤大小、术前纯音听阈以及内听道扩大与术后听力保留率无关(P>0.05),术前言语识别率、术中ABR和ECochG联合监测、肿瘤和神经粘连与否与术后听力保留率相关(P<0.05)。结论听神经瘤切除术中ABR和ECochG连续监测对指导手术和提高术后听力保留率有重要意义,肿瘤与神经粘连是术后听力保留的重要影响因素,手术技巧、术前听力、肿瘤大小、内听道扩大等是否是术后听力保留的影响因素需扩大样本进一步研究验证。  相似文献   

4.
From a series of 35 cases with intraoperative monitoring of acoustic evoked brainstem responses 4 cases with cerebellopontine angle surgery are presented in detail. The aim of neuromonitoring is to provide the surgeon with an additional instrument to assess the functional state of the hearing pathway with objective neurophysiological criteria during dissection near the eighth nerve and brainstem. Thus, a near total loss of potential during a neurovascular decompression of the trigeminal nerve could be reversed by modifying the surgical procedure. In 2 cases of acoustic neurinoma with preserved wave I this peak was obtainable throughout the procedure with a good postoperative result. Transient amplitude attenuation and latency increase was seen with a meningioma, which normalized before the end of operation with good postoperative hearing and brain-stem function. The relationship between intraoperative BAEP changes and postoperative brain-stem and eighth nerve function, and the value of neuromonitoring are discussed with regard to surgery around the internal auditory meatus and the eighth nerve.  相似文献   

5.
目的 探讨听神经瘤手术中听觉监护的意义。比较听性脑干反应(ABR)和蜗神经动作电位(cochlear nerve action potential,CNAP)在听觉监护应用中的价值。方法 回顾性分析我中心12例保留听力手术的听神经瘤患者资料及术中情况,患者术前均有实用听力(AAO-HNS分级A级、B级),可引出ABR波形,V波分化可,所有手术均采取乙状窦后径路摘除肿瘤。所有患者均全程ABR监护,术中打开脑膜后联合监测CNAP。结果 手术过程中所有患者ABR波形较术前基线均有不同程度的变化,可记录到V波潜伏期均较基线延长(0.68±0.41)ms。CNAP波幅个体差异性较大,可记录到的P1潜伏期均较基线延长(0.25±0.16)ms。12例中有8例(66.7%)患者术后保留可用听力;另外4例(33.3%)术后达不到可用听力,此4例患者ABR表现为3例V波消失,1例V波潜伏期延长。CNAP表现为2例CNAP的P1消失,2例P1延长。电钻钻磨造成的震动和噪声、手术时神经被牵拉或热损伤后等急性损伤后ABR和CNAP波幅均出现短时间急剧下降,手术暂停5 min后,部分患者波幅可在一定程度恢复。结论 听神经瘤手术中ABR和CNAP对于听觉监护均有一定意义。ABR波形稳定可靠,但叠加时间相对较长;CNAP叠加快速,可提升监测灵敏度,但波形变异度较大。电钻钻磨造成的震动和噪声、操作过程中对神经组织的牵拉以及热损伤均被及时监控,两者联合应用可提升听神经瘤手术的听觉功能保留率。  相似文献   

6.
The aim of this study was to evaluate the efficacy of an intraoperative monitoring hearing preservation strategy that includes simultaneous recordings of an auditory brainstem response (ABR) and non-invasive electrocochleography (ECochG). The combined ABR and tympanic membrane (TM) ECochG testing was performed in 74 patients undergoing acoustic neuroma (AN) surgery. In addition, EMG recordings were conducted to monitor the facial nerve function. Hearing was preserved in 19 of the 30 patients with residual hearing prior to surgery (63%), and facial nerve function was maintained in 89% of the patients. In most cases, the presence of both auditory brainstem and TM-ECochG responses at the end of surgery was associated with preservation of postoperative functional hearing; however, eight patients had a TM-ECochG response with a complete loss of the ABR, pointing to deafferentation of the auditory nerve. Tumour size and preoperative hearing thresholds significantly affected the postoperative hearing. The TM-ECochG response yielded large reproducible responses, which, in some patients, was the only way to monitor the auditory function. This auditory monitoring approach offers a valuable auditory tool that helps to improve the hearing preservation during AN surgery.  相似文献   

7.
The aim of this study was to evaluate the efficacy of an intraoperative monitoring hearing preservation strategy that includes simultaneous recordings of an auditory brainstem response (ABR) and non-invasive electrocochleography (ECochG). The combined ABR and tympanic membrane (TM) ECochG testing was performed in 74 patients undergoing acoustic neuroma (AN) surgery. In addition, EMG recordings were conducted to monitor the facial nerve function. Hearing was preserved in 19 of the 30 patients with residual hearing prior to surgery (63%), and facial nerve function was maintained in 89% of the patients. In most cases, the presence of both auditory brainstem and TM-ECochG responses at the end of surgery was associated with preservation of postoperative functional hearing; however, eight patients had a TM-ECochG response with a complete loss of the ABR, pointing to deafferentation of the auditory nerve. Tumour size and preoperative hearing thresholds significantly affected the postoperative hearing. The TM-ECochG response yielded large reproducible responses, which, in some patients, was the only way to monitor the auditory function. This auditory monitoring approach offers a valuable auditory tool that helps to improve the hearing preservation during AN surgery.  相似文献   

8.
Hearing preservation following suboccipital removal of acoustic neuromas   总被引:2,自引:0,他引:2  
Advances in the diagnosis and intraoperative management of acoustic neuromas have greatly reduced the incidence of neurologic deficits following their removal. Ninety-three patients underwent acoustic tumor removal during a 41/2-year period, and hearing preservation was attempted in 20 cases. Hearing was preserved in 65% of the entire series, and excellent results were obtained in tumors less than 1.5 cm. No patient with a tumor greater than 1.5 cm had serviceable hearing preserved when total tumor removal was performed. Two patients, one with neurofibromatosis and one with an acoustic neuroma in an only-hearing ear, had planned partial tumor removal with preservation of hearing. Preoperative auditory brainstem response results were not predictive of postoperative hearing preservation. Intraoperative auditory brainstem response monitoring demonstrated that loss of wave V consistently correlated with loss of hearing postoperatively, whereas persistence of wave V (with a latency prolongation not exceeding 3.00 ms) was predictive of successful hearing preservation regardless of latency increases.  相似文献   

9.
OBJECTIVE/HYPOTHESIS: Sensorineural hearing loss is a disturbing complication of microvascular decompression (MVD) for trigeminal neuralgia with an incidence of 1% to 23.8%. Cerebellar retraction with increasing I-V interpeak latency (IPL) during intraoperative brainstem auditory evoked potentials (BAEP) has been identified as the chief cause of acoustic injury. This study was designed to eliminate cerebellar retraction by a modification of the standard suboccipital craniectomy. STUDY DESIGN: Nine consecutive patients undergoing surgery for trigeminal neuralgia were prospectively selected for this study between 1994 and 1995. METHODS: Preoperative and postoperative audiograms were obtained. Preoperative and intraoperative BAEPs were performed. The surgical modification describes initiating a partial mastoidectomy to enhance early recognition and delineation of the sigmoid and transverse sinuses crucial to maximizing the lateral extent of the craniectomy. The additional exposure gained by this technique allows for improved visualization of the brainstem without cerebellar retraction. RESULTS: All patients were relieved of neuralgic pain. Postoperative IPL values were not significantly different from preoperative values (4.9+/-0.6 vs. 4.7+/-0.3 ms). Maintaining IPL of less than 1.5 ms is considered critical for preventing injury to the auditory nerve. In this study the average increase in postoperative IPL was 0.25 ms for the ipsilateral ear and 0.1 ms for the contralateral ear. CONCLUSIONS: The authors offer a surgical modification of the standard suboccipital craniectomy and furnish intraoperative neurophysiologic data to demonstrate how cerebellar compression can be eliminated and hearing preserved in MVD for trigeminal neuralgia.  相似文献   

10.
Intraoperative monitoring of the auditory pathway by means of either electrocochleography or auditory brainstem response audiometry is valuable during hearing preservation vestibular schwannoma (VS) surgery. A more than 75% intraoperative reduction of the amplitude of these evoked auditory potentials was thought to be related with clear hearing compromise of hearing. We identified 22 patients who satisfied this intraoperative criterion in a cohort of 86 consecutive patients who had attempted hearing preservation VS surgery. The surgical step that temporally coincided with the above event was considered to be the most critical step for hearing monitoring during this kind of surgery. Most frequently, drilling of the internal auditory canal and direct tumor resection were associated with the aforementioned changes, but also drilling of the cortical temporal bone at the very beginning of surgery or the opening of the dura could be implicated. This profound intraoperative amplitude decrease was associated with a profound postoperative hearing impairment in 84% of the cases.  相似文献   

11.
听神经瘤术中连续听力监测的初步探讨   总被引:2,自引:0,他引:2  
目的探讨听神经瘤外科术中连续听力监测的意义。方法采用乙状窦人路,在听性脑干反应(auditory brainstem response,ABR)和耳蜗电图(electrocochleogram,ECochG)监测下完成的听神经瘤切除术10例。对手术过程和术后听力结合术中监测进行分析。结果10例听神经瘤术前听力A级3耳,B级4耳,C级3耳(美国耳鼻咽喉头颈外科学会分级标准)。术前的ABR检查Ⅰ、Ⅲ、Ⅴ波存在者5耳(A级3耳,B级2耳),仅见Ⅰ波者5耳(B级2耳,C级3耳)。麻醉后手术前的监测显示:Ⅰ、Ⅲ、Ⅴ波存在者2耳,仅Ⅰ波存在者6耳,以复合动作电位(compound action potential,CAP)的N1波代替波Ⅰ;无波形者2耳。术后听力保留2耳,肿瘤均〈2cm,术前听力都为A级;连续听力监测显示1耳术中及术毕时Ⅰ、Ⅲ、Ⅴ持续存在,1耳Ⅰ、Ⅲ波存在,Ⅴ波消失;术后听力均为A级。听力未保留8耳,其中6耳术中监测时仅CAP的N1(波Ⅰ)存在,手术过程中夹内听动脉或处理内耳道处肿瘤时,4耳CAP波幅明显下降,甚至下降至0,术毕又恢复至术前的50%~60%或正常;1耳蜗神经与肿瘤一并切除,但CAP始终存在;1耳因牵拉脑干侧的耳蜗神经,CAP波幅降至0,手术结束亦未恢复。2耳为全身麻醉后术前监测中未引出任何波形者,其中1耳术中切除部分肿瘤后,出现CAP波,但波幅低,直至术毕;1耳始终未出现波形。结论联合应用ABR和ECochG术中监测,对提高听力保护率有积极意义,能及时反映术中与保留听力相关的敏感手术步骤,然而外科医师的熟练的解剖和精确的手术技巧是手术成功的最基本因素。  相似文献   

12.
Intraoperative monitoring of brainstem auditory evoked potentials (BAEP) has been widely utilized to reduce the incidence of postoperative hearing disturbance due to cerebellopontine angle manipulations. The prolongation of wave V of BAEP is usually used as a criterion to warn the surgeons to modify their surgical maneuvers. However, it is not known whether all neuropathological changes are avoided if BAEP latency intraoperatively returns to the baseline level or some neuropathological changes 'silently' occur even if BAEP normalizes. The aim of this study was to experimentally clarify this point that would be important for the long-term prognosis of patients' hearing. The cerebellopontine angle portion of the auditory nerve was quantitatively compressed in the rats and reversible prolongation of BAEP latency was reproduced just as it occurs during surgery in humans. Twenty-four hours after the compression, the auditory nerve was removed for beta-APP immunostaining to investigate the degree of axonal injury. The results of the present study disclosed that axonal injury occurred even in the cases where the intraoperative normalization of prolonged wave IV (equivalent to wave V in humans) latency had been obtained. Therefore, the interpretation of BAEP changes based only on the prolongation of the latency of BAEP was not enough to prevent the auditory nerve from developing morphological changes. Changes in the amplitude of wave V of BAEP appears to be more sensitive than its latency change as an intraoperative indicator for axonal injury in the auditory nerve.  相似文献   

13.
OBJECTIVES: To compare the hearing preservation results obtained with use of two intraoperative eighth nerve monitoring methods, cochlear nerve action potential (CNAP) and auditory brainstem response (ABR), during complete acoustic neuroma (AN) resection. STUDY DESIGN: Retrospective. SETTING: Tertiary referral center. PATIENTS: Thirty-three consecutive patients who underwent hearing preservation AN surgery. INTERVENTIONS: Intraoperative monitoring by CNAP and/or ABR during AN resection. MAIN OUTCOME MEASURE: Postoperative hearing. Hearing preservation was considered achieved for pure-tone average < or =50 dB and speech discrimination > or =50%. RESULTS: Thirty-two patients met inclusion criteria for the study. Monitoring was successfully performed in 23 of 25 patients (92%) who underwent attempted CNAP monitoring and 13 of 27 (48%) who underwent attempted ABR monitoring. When tumor size was < or =20 mm in greatest dimension, hearing preservation was achieved in 12 of 18 patients (67%) monitored with CNAP, versus 2 of 8 patients (25%) not monitored with CNAP (p = 0.05). Monitoring by ABR did not improve hearing preservation rates compared with those not monitored with ABR (40% vs. 63%). At the completion of surgery, the presence or absence of CNAP predicted the presence or absence of hearing preservation in 18 of 23 cases (p = 0.01), while ABR successfully predicted hearing results in 10 of 13 cases (p = 0.05). CONCLUSIONS: When CNAP and ABR monitoring techniques during AN surgery were compared, CNAP was more frequently obtainable. Monitoring by CNAP was significantly associated with a higher chance of hearing preservation. Monitoring by ABR did not have a positive influence on hearing preservation results. Both ABR and CNAP were useful for predicting postoperative hearing.  相似文献   

14.
OBJECTIVE: To investigate the efficiency of a new method of brainstem auditory-evoked potential (BAEP) monitoring during complete vestibular schwannoma (VS) resection with attempted hearing preservation. MATERIAL AND METHODS: Dedicated software providing near real-time recording was developed using a rejection strategy of artifacts based on spectral analysis. A small sample number (maximum 200) is required and results are obtained within 10 s. Fourteen consecutive patients with hearing class A operated on for VS, in an attempt to preserve hearing, participated in the investigation. Postoperatively, 7 patients (50%) had useful hearing (hearing class A, 4/14; hearing class B, 3/14) on the operated side. Seven patients (50%) were reduced to hearing class D. RESULTS: Drilling of the internal auditory canal (IAC) and tumor removal at the lateral end of the IAC were identified as the two most critical steps for achieving hearing preservation. Intraoperative BAEP monitoring was sensitive in detecting auditory damage with useful feedback but its effectiveness in preventing irreversible hearing impairment was not demonstrated in this study. CONCLUSION: Combined BAEP and direct auditory nerve monitoring using the same equipment will be performed in the future in an attempt to enhance the chances of preventing irreversible hearing damage, and possibly to improve the hearing outcome significantly.  相似文献   

15.
Anacusis following hearing preservation surgery for acoustic neuroma removal in which the cochlear nerve was preserved has been explained on the basis of neural or vascular compromise. In the absence of pathologic evidence for either theory, a physiologic model was chosen. Electrical promontory stimulation with monitoring of subjective and electrically evoked auditory brainstem responses was undertaken. A positive response to stimulation suggests a vascular impairment of the cochlea sparing the cochlear nerve and spiral ganglion. The absence of response suggests loss of neural integrity at the level of the spiral ganglion or cochlear nerve. Six patients who suffered anacusis following hearing preservation surgery for acoustic neuroma were studied. Data regarding electrical promontory stimulation, auditory brainstem responses, and implications of the possible role of cochlear implantation are discussed.  相似文献   

16.
C Strauss  R Fahlbusch  M Berg  T Haid 《HNO》1989,37(7):281-286
Various successful approaches are available for acoustic neurinoma surgery, permitting total tumor removal and preservation of cranial nerve function. In smaller and medium sized tumors excellent results can be achieved with respect to facial and cochlear nerve function using the transtemporal approach. For larger tumors similar results can be achieved by the suboccipital approach. The results of 45 completely removed large acoustic neurinomas all operated upon via the suboccipito-lateral approach with microsurgical techniques and neurophysiological monitoring are presented. The average tumor size, excluding the portion within the internal auditory canal was 3 cm. Anatomical preservation of the VIIth cranial nerve was achieved in nearly all cases. Satisfactory to excellent facial nerve function was preserved in 70% of all cases. Initial hearing was preserved in 29%. However delayed postoperative hearing loss was encountered in 13%. Therefore definite hearing preservation was achieved in 16% of the cases. Intraoperative monitoring, especially of auditory evoked potentials, was very helpful in achieving these functional results.  相似文献   

17.
The surgical results in 78 recent cases of total removal of unilateral acoustic neuroma in which an attempt was made to preserve cochlear function have been added to the authors' previous series of 66 cases to evaluate the factors influencing the ability to preserve useful hearing. Useful hearing was defined by speech reception threshold no poorer than 70 dB and a discrimination score of at least 15%. Analysis using a logistic regression model showed that certain preoperative clinical parameters such as tumor size, speech discrimination score, and gender were significantly correlated with hearing outcome. Favorable outcome was significantly correlated with smaller tumor size, higher preoperative speech discrimination score, and male sex. From this data, an explicit formula was devised for predicting hearing outcome for an individual patient. In four cases with useful hearing preserved, there was improvement of greater than 15 percentage points in speech discrimination scores. While preoperative auditory brainstem responses were not predictive of hearing preservation, monitoring of intraoperative auditory evoked potentials was predictive of hearing outcome in selected cases. Specifically, when wave V was unchanged at the end of the operation, even if it may have been transiently lost during surgery, useful hearing was invariably preserved.  相似文献   

18.
《Acta oto-laryngologica》2012,132(1):53-61
Objective To investigate the efficiency of a new method of brainstem auditory-evoked potential (BAEP) monitoring during complete vestibular schwannoma (VS) resection with attempted hearing preservation.

Material and Methods Dedicated software providing near real-time recording was developed using a rejection strategy of artifacts based on spectral analysis. A small sample number (maximum 200) is required and results are obtained within 10 s. Fourteen consecutive patients with hearing class A operated on for VS, in an attempt to preserve hearing, participated in the investigation. Postoperatively, 7 patients (50%) had useful hearing (hearing class A, 4/14; hearing class B, 3/14) on the operated side. Seven patients (50%) were reduced to hearing class D.

Results Drilling of the internal auditory canal (IAC) and tumor removal at the lateral end of the IAC were identified as the two most critical steps for achieving hearing preservation. Intraoperative BAEP monitoring was sensitive in detecting auditory damage with useful feedback but its effectiveness in preventing irreversible hearing impairment was not demonstrated in this study.

Conclusions Combined BAEP and direct auditory nerve monitoring using the same equipment will be performed in the future in an attempt to enhance the chances of preventing irreversible hearing damage, and possibly to improve the hearing outcome significantly.  相似文献   

19.
The surgical results in 69 patients with unilateral tumors of the cerebellopontine angle or internal auditory canal in whom total tumor removal was accomplished, and in whom an attempt was made to preserve hearing, are presented. The success rate of preservation of hearing and facial nerve function was correlated with the size of the tumor. Useful hearing, as defined by speech reception threshold no poorer than 70 dB and a discrimination score of at least 15%, was preserved in 73% of cases in which the tumor extension to the posterior fossa was no greater than 0.5 cm. In contrast, useful hearing was preserved in 22% of cases in which posterior fossa extension was greater than 2.5 cm. No significant correlation was found between preoperative evoked responses and success in preservation of hearing. The techniques and value of intraoperative monitoring of electrocochleogram (ECoG) and brain stem evoked responses are discussed. A theory of pathogenesis of intraoperative hearing loss, based on correlation of changes in evoked responses and simultaneous surgical events, is presented.  相似文献   

20.
Hearing preservation in acoustic neuroma surgery.   总被引:3,自引:0,他引:3  
This article reviews the Montreal experience of hearing preservation in acoustic neuroma surgery. The medical records since 1995 of 36 patients who underwent acoustic neuroma extirpation with the intent to preserve hearing were examined. Intraoperative monitoring was conducted using auditory brainstem response measurement with electrocochleography via a transtympanic electrode. The role of intraoperative monitoring in guiding surgical technique and its correlation with postoperative hearing outcome are discussed. A review of the literature regarding hearing preservation in acoustic neuroma surgery is included.  相似文献   

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