老年腰椎间盘突出症或腰椎管狭窄症再手术的探讨

目的分析老年腰椎间盘突出症或腰椎管狭窄症的初次手术失败原因,提出再手术的方法及注意事项。方法对24例腰间盘突出症或腰椎管狭窄症第1次手术失败,导致术后症状无明显好转或加重而再手术(24例患者全部行彻底椎板减压,钉棒的内固定植骨融合)资料进行回顾性分析。结果初次手术失败原因主要为椎间盘摘除术后或腰椎管狭窄减压术后未做恢复脊柱高度及脊柱稳定手术,造成脊柱不稳,椎管或神经根管进一步狭窄,导致神经根受压所致的根性痛。再次手术后24例病人经1年以上随访,术后效果良好,优良率91.67%。结论钉棒系统加Cage联合应用是治疗腰椎间盘突出或腰椎管狭窄症术后复发的有效方法。     

腰椎间盘突出症术后中远期并发症的原因分析及对策

随着腰椎间盘突出症手术的普及和接受手术患者的增加,国内外对该手术的优缺点及并发症的相关报道也逐渐增多.有关腰椎间盘突出症中远期手术疗效各家报道不一,优良率为83.8%～97.1%[1,2].以往将腰椎间盘术后中远期疗效不佳的原因归结于椎间盘突出症的复发,而现在普遍认为影响椎间盘突出症中远期疗效的原因是多方面的[3].笔者对1997至2007年我院手术治疗的220例腰椎间盘突出症患者中出现术后中远期并发症而再次就诊或手术的28例进行回顾性分析.     

腰椎间盘突出症首次手术失败76例相关因素分析

目的对腰椎间盘突出症手术失败的原因进行分析,旨在提高首次手术的成功率。方法对1997—2007年76例腰椎间盘突出症手术失败患者进行回顾性分析,对患者的初次术前诊断、手术方法、再术前临床表现、影像学检查进行评估。探讨首次手术失败原因。结果76例首次手术患者术后获得随访,随访时间12—120个月,平均60个月。首次手术出现术后症状复发、腰椎不稳等问题,需再次手术治疗,初次手术失败中行开窗、扩大开窗法腰椎间盘摘除术占52．8％。结论手术失败的原因主要有：未严格掌握手术适应证多间隙突出遗漏定位错误及髓核摘除不彻底、并发后腰椎不稳等。     

小儿腰椎间盘突出症的手术治疗

目的观察手术治疗小儿腰椎间盘突出症的疗效,并探讨手术方式。方法小儿腰椎间盘突出症患者23例,均采用手术治疗。结果术后随访13—38个月,疗效为优18例,良4例,可1例。结论手术治疗小儿腰椎间盘突出症疗效良好,椎板开窗减压突出髓核组织摘除术疗效满意。     

腰椎间盘突出症再手术原因分析（附32例报告）

对３２例行二次手术的腰椎间盘突出症患者的临床资料进行了分析，发现再手术原因为腰椎间盘突出术后复发、另一间隙再突出、合并腰椎管狭窄、下腰椎手术失败综合征及第一次手术定位错误。     

60例腰椎间盘突出症患者术后MRI检查结果分析

目的探讨腰椎间盘突出症手术后MRI检查的意义。方法对60例腰椎间盘突出症手术后的MRI检查结果作回顾性分析。结果本组MRI显示,10例无明显异常,术后复发15例,硬膜外纤维化24例,椎管狭窄26例,椎间隙感染5例,脑脊液漏1例。结论术后MRI检查有助于腰椎间盘突出症手术并发症的诊断,并指导治疗。     

腰椎间盘突出症再次手术原因的分析

我们自1964～1979年收治8例因腰椎间盘突出症术后症状未缓解或复发又施行第二次手术的患者,现将其原因作一分析。一、神经根粘连2例。1例为第四、五腰椎间盘突出症,曾于1964年3月行左侧椎板切除摘取椎间盘组织,术后症状稍减轻,     

开窗式手术治疗腰椎间盘突出症的疗效观察

目的探讨开窗式手术治疗腰椎间突出症的临床疗效。方法对243例腰椎间盘突出症患者行开窗式手术治疗,对其疗效做出评价。结果 181例患者随访12个月以上,根据日整会JOA术后评分标准,平均改善率为77.79%,疗效显著。结论开窗式手术是治疗腰椎间盘突出症的一种有效方法,它具有切口小、出血少、术中对脊柱结构破坏少、对脊柱稳定性影响小、术后并发症少及患者康复比较快等优点。     

显微镜下微创椎间盘取出术治疗腰椎间盘突出症疗效观察

目的评价显微镜下微创椎间盘取出术治疗腰椎间盘突出症的手术效果。方法选择腰椎间盘突出症患者410例,均行择期显微镜下微创腰椎间盘取出术。于术前、术后3个月、术后12个月分别行疼痛视觉模拟评分(VAS);采用日本骨科协会腰椎神经功能(JOA)评分评估神经功能缓解程度,采用Oswestry量表ODI指数评估生活质量。随访6~24个月,采用Epstein法以手术优良率评价临床疗效。结果 410例患者手术时间为50~90(66.0±5.3)min,术中出血量为10~40(30.0±6.5)m L,术中出现脑脊液漏3例,无神经损伤者。410例患者均获得随访,术后3、12个月VAS、JOA评分及ODI指数均优于术前(P均<0.05)。手术优良率为91.2%。随访中出现椎间盘突出症复发8例。结论显微镜下微创椎间盘取出术治疗腰椎间盘突出症术中出血少,手术时间较短,对神经及骨性结构损伤较小,手术并发症少。     

MED治疗腰椎间盘突出症效果观察

目的观察后路显微内窥镜下腰椎间盘切除术（MED）治疗腰椎间盘突出症的临床效果。方法应用MED治疗腰椎间盘突出症86例。结果平均手术时间65min,平均术中出血量52ml,发生定位错误并神经根损伤1例,硬脊膜破裂1例。术后平均随访14个月,按照Nakai评价标准评定疗效,优64例,良16例,可6例,差0例,优良率为93．02％。结论MED治疗腰椎间盘突出症,疗效可靠、创伤小、出血少、对脊柱稳定性结构损伤小、术后恢复快,但可能出现神经根损伤等并发症。     

经皮椎间孔镜在治疗中老年腰椎间盘突出症中的应用

目的评价应用经皮椎间孔镜(PTED)治疗中老年腰椎间盘突出症的临床效果和价值。方法前瞻性研究分析2016年3月至2018年9月空军特色医学中心骨科采用PTED切除突出椎间盘髓核减压治疗的50～72岁腰椎间盘突出症患者,共50例,并以同期常规开放椎板开窗或半椎板切除减压突出椎间盘髓核切除手术的50～71岁患者50例为对照组。比较2组患者术中出血量、手术时间、术后住院时间。以术后1 d、1个月、3个月疼痛视觉模拟评分(VAS)和术后3个月Oswestry功能障碍指数(ODI),及术后6个月改良MacNab标准评定手术疗效。手术前及术后3～6个月行MRI检查,观察手术前后椎管及椎间盘突出的变化。使用STATA 12.0统计软件进行统计分析。结果 2组患者年龄、术前VAS和ODI评分差异无统计学意义(P0.05),术后VAS和ODI评分较术前均显著下降(P0.01);PTED组术后1 d、1个月的VAS评分显著低于对照组(P0.01)。术后3个月,2组VAS和ODI评分差异无统计学意义(P0.05);术后6个月,2组改良MacNab标准评定功能差异无统计学意义(P0.05);PTED组术中出血量、术后住院时间显著少于对照组(P0.01);2组手术时间无统计学差异(P0.05)。MRI检查结果显示,与术前比较,2组术后3～6个月椎间盘突出均消失或明显减小,椎管通畅、面积明显增大。结论 PTED技术治疗中老年腰椎间盘突出症,中期疗效与单纯开放手术相当,但PTED早期疗效好、损伤小、恢复快、并发症少。     

Zina percutaneous screw fixation combined with endoscopic lumbar intervertebral fusion under intraoperative neuromonitoring: A case report

Introduction:Traditional open discectomy and intervertebral fusion surgery is the common strategy for lumbar disc herniation (LDH). However, it has the disadvantages of long recovery time and severe paravertebral soft tissue injury. Zina percutaneous screw fixation combined with endoscopic lumbar intervertebral fusion (ZELIF), as a novel minimally invasive surgical technique for LDH, has the advantages in quicker recovery, less soft tissue destruction, shorter hospital stays and less pain. We report a novel technique of ZELIF under intraoperative neuromonitoring (INM) for the treatment of LDH.Patient concerns:A 51-year-old male presented to our hospital with left lower extremity pain and numbness for 1 year.Diagnosis:Lumbar disc herniation (LDH).Interventions:This patient was treated with Zina percutaneous screw fixation combined with endoscopic neural decompression, endplate preparation, and intervertebral fusion through Kambin''s triangle. Each step of the operation was performed under INM.Outcomes:The follow-up period lasted 12 months; the hospitalization lasted 4 nights; the blood loss volume was 65 ml, and the time of operation was 266 min. INM showed no neurological damage during the surgery. No surgical complications, including neurological deterioration, cage migration, non-union, instrumentation failure or revision operation, were observed during the follow-up period. Visual Analogue Scale (VAS) score reduced from 7 to 1; the Oswestry Disability Index (ODI) decreased from 43 to 14; the EQ-5D score was 10 preoperatively and 15 at the final follow-up visit; the Physical Component Summary of the 36-Item Short Form Health Survey (SF-36) was 48 preoperatively and 49 at the last follow up visit; the SF-36 Mental Component Summary was 47 before surgery and decreased to 41 postoperatively.Conclusion:ZELIF under INM may represent a feasible, safe and effective alternative to endoscopic intervertebral fusion and percutaneous screw fixation, for decompressing the lumbar''s exiting nerve root directly with minimal invasion in selected patients.     

Zessys椎间孔成型术与传统椎间孔成型术治疗远处脱垂型腰椎间盘突出症的临床疗效比较

目的比较Zessys椎间孔成型术与传统椎间孔成型术治疗远处脱垂型腰椎间盘突出症的临床疗效。方法选择2017-08~2019-02漯河医学高等专科学校第二附属医院收治的34例远处脱垂型腰椎间盘突出症患者的临床资料,其中17例采用Zessys椎间孔成型术治疗(A组),另17例采用传统椎间孔成型术治疗(B组)。比较两组手术时间、透视次数、术中出血量,并比较两组术前、术后第3天、术后第6个月患者的疼痛视觉模拟量表(VAS)评分、Oswestry功能障碍指数(ODI)评分、日本骨科协会评估治疗分数(JOA)评分。结果A组手术时间短于B组,术中透视次数少于B组,差异有统计学意义(P<0.05)。两组术中出血量比较差异无统计学意义(P>0.05)。两组术后第3天、第6个月的VAS、ODI评分显著低于术前(P<0.05),JOA评分显著高于术前(P<0.05);但两组在术前及术后不同时间点的VAS、ODI、JOA评分比较差异均无统计学意义(P>0.05)。结论与传统椎间孔成型术比较,Zessys椎间孔成型术在治疗远处脱垂型腰椎间盘突出症中可缩短手术时间,减少术中医患X线暴露,值得推广。     

YKL-40 in human lumbar herniated disc and its relationships with nitric oxide and cyclooxygenase-2

The basic pathophysiology of intervertebral disc degeneration and low back pain remains unclear. It has been hypo-thesized a role of biochemical mediators of inflammation and tissue degradation in intervertebral disc degeneration and herniation. Chitinase 3-like protein 1 (YKL-40) is a glycoprotein mainly secreted by chondrocytes which has been proposed as a possible marker of inflammation and/or cartilage alterations. OBJECTIVE: To investigate the YKL-40 presence in human lumbar disc tissue culture and its possible relationships with some substances relevant in inflammation such as cyclooxygenase-2 (COX-2) and nitric oxide (NO). PATIENTS AND METHODS: We analyzed lumbar discs from 19 patients who underwent surgery for lumbar disc herniation at L4-L5 or L5-S1 levels. The specimens were cultured and incubated for 72 hours. At the end of incubation, the supernatants were assayed for presence and concentration of YKL-40, COX-2 and NO. RESULTS: YKL-40 was detectable in all the samples analyzed. Mean (+/-SD) concentration was 1.54+/-1.29 ng/ml/mg compared to dry weight. COX-2 and NO levels were 25.25+/-11.42 pg/ml/mg and 1.3+/-1.8 microM/mgx10(-2), respectively. A correlation was found between YKL-40 and COX-2 (r=0.579, p<0.05) and YKL-40 and NO (r=0.509, p<0.05). CONCLUSION: To our knowledge, this is the first report demonstrating YKL-40 release by intervertebral disc culture. It may contribute to better clarify the role of this protein in the pathophysiology of discal degeneration and inflammation as confirmed by its relationships with COX-2 and NO in disc tissue culture.     

C臂导向经皮穿刺注射臭氧治疗腰椎间盘突出症58例疗效观察

目的探讨经皮穿刺注射臭氧治疗腰椎间盘突出症的疗效。方法 58例患者在C臂引导下行病变椎间盘盘内穿刺,盘内和椎旁注射臭氧,术后随访6～12个月。结果根据改良的Macnab疗效评定标准评定:优27例,良19例,可10例,差2例,优良率为79.3%(46/58),总有效率为96.6%(56/58)。结论 C臂导向经皮穿刺注射臭氧治疗腰椎间盘突出症,效果满意,且操作方便,对病人创伤小,医疗成本低,值得推广。     

Establishing a critical pathway for Korean medical management of lumbar disc herniation: A modified Delphi consensus process

A modified Delphi method was used to establish a consensus. Stakeholders and experts were invited to participate in the expert panel. Best practice statements and decision-making questionnaires were distributed to the panel. Panel members were asked to mark “Strongly disagree” to “Strongly agree” after a series of statements over several rounds until either a consensus was reached or the decision-making method was deemed unsuitable for reaching a consensus.The most common cause of lumbar pain is intervertebral degeneration, which leads to degenerative disc disease and lumbar disc herniation. There is a lack of unanimity regarding appropriate patient protocols and rehabilitation expectations for Korean medical care. The long-term viability of Korean medical treatment, further adoption in the institutional setting, and specific patient outcomes are contingent on the existence of appropriate Korean medical programs.A Korean medical expert panel of 17 practitioners employed a modified Delphi method to achieve consensus on Korean medical care for lumbar disc herniation. The panel first reviewed the literature and guidelines relevant to Korean medical treatment for lumbar disc herniation. The panel members considered questionnaires intended to determine “standardized” Korean medical care recommendations for patients with a wide range of symptoms of lumbar disc herniation. Each panel member participated in a round of voting, which was followed by an opinion-collecting session online. Consensus was defined as a ≥75% agreement among the respondents.In the first round, 144 questionnaires across 5 domains were administered to the expert panels. After reviewing the responses and open-ended comments collected in the first round, the authors modified the questionnaires to 53 items and proceeded. In round 2, consensus was achieved in all 53 survey questions. The final treatment pathway comprised a standardized and comprehensive care approach for lumbar disc herniations in 4 types of medical institutions.This study identified a core set of evidence- and consensus-based principles that are essential to a comprehensive model of care, incorporating identification, referral, and management of patients with lumbar disc herniation.     

Outcomes of epiduroscopic laser ablation in patients with lumbar disc herniation

Recently, trans-sacral epiduroscopic laser decompression (SELD) using flexible epiduroscopy and laser system is 1 of the options for minimally invasive surgery in herniated lumbar disc. However, outcomes after SELD in patients with disc herniation of lumbar spine are not proven worldwide. The authors reported clinical, surgical, and radiological outcome after SELD in patients with mild to moderate disc herniation.Between 2015 and 2018, eighty-two patients who underwent SELD for single level disc herniation with a minimum follow-up of 6.0 months were investigated retrospectively. Clinical outcomes were assessed using the visual analog scale for low back and leg pain and Odom''s criteria for patient satisfaction. Also, surgical outcomes, including complications, recurrences, and revision surgeries, and radiological outcomes using regular simple radiograph were analyzed.The mean visual analog scale score of low back pain and leg pain improved from 5.43 ± 1.73 and 6.10 ± 1.67 to 2.80 ± 1.43 and 3.58 ± 2.08 at the final follow-up (p < 0.001). On the other hand, according to Odom''s criteria, the success rate (excellent or good results at 6 months after surgery) was 58.5%. Surgical complications occurred in 7 patients (8.5%), including dura puncture during the procedure, transient headache or nuchal pain, and transient mild paralysis. The rate of additional procedures after SELD was 17.1% (6 patients of revision surgery and 8 patients of an additional nerve block).Our findings demonstrated that SELD for lumbar disc herniation achieved less favorable patient satisfaction compared with previous studies. Further study is needed to clarify the influencing factors on the clinical outcomes of SELD.     

Expression and significance of VEGF and p53 in degenerate intervertebral disc tissue

ObjectiveTo investigate the mechanism of expression and significance of vascular endothelial growth factor (VEGF) and p53 in degenerate intervertebral disc tissue.MethodsPathological sections collected from 156 patients with lumbar disc herniation after surgery were tested by immunohistochemistry method, for evaluation of the expression of VEGF and p53 in degenerate intervertebral disc tissue.Results98 cases (62.8%) with vascular infiltration phenomenon are found, and positive rates of VEGF and p53 in degenerate intervertebral disc tissue are 73.42% (116/156) and 58.97% (92/156); co-expression rate is 53.2%(83/156); the expression rates of VEFG and p53 are significantly higher in the tissue with blood vessel infiltration than in the tissue without infiltration; there is a close relationship of VEGF with p53.ConclusionsVEGF and p53 gene synergetic express in degenerate intervertebral disc tissue, working together in neovascularization and infiltration, and accelerating intervertebral disc tissue degeneration.     

悬吊核心肌群训练治疗腰椎间盘突出症的临床疗效观察

目的 观察悬吊核心肌群训练治疗腰椎间盘突出症的临床疗效及其对竖脊肌、多裂肌积分肌电值(iEMG)的影响.方法 选择2018-01～2020-11吉林省一汽总医院康复医学科收治的64例腰椎间盘突出症患者,采用随机数字表法将其分为观察组和对照组,每组32例.对照组采用常规康复治疗,观察组在对照组治疗方案基础上增加悬吊核心肌...