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1.
Khafiz'yanova RKh Aleyeva GN Mukhutdinov DA 《Bulletin of experimental biology and medicine》2007,143(4):446-448
Single parenteral administration of dimephosphon, mexidol, and ketorolac produces a lymphotropic effect. Dimephosphon directly
affects the lymph system by increasing the number of functioning lymph capillaries and contractile activity of the walls and
valves of small intestinal mesenteric lymphangions in rats, which leads to stimulation of lymph circulation. Mexidol and ketorolac
increased only lymph flow rate in the thoracic lymph duct, which attested to their indirect effect of the lymph system (presumably
associated with stimulation of lymph formation). Despite these differences in the mechanisms of lymphotropic effect, all these
drugs activate lymph drainage and, hence, transporting function of the lymph system.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 4, pp. 423–426, April, 2007 相似文献
2.
We studied the kinetics of thietazole distribution in the liver, brain, kidneys, spleen, heart, skeletal muscles, lungs, adipose
tissue, and testicles after single and repeated administration of this drug. Single and repeated administration of thietazole
was followed by elimination of this drug from the blood into organs and tissues. After repeated administration, thietazole
was selectively accumulated in the spleen.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 5, pp. 555–557, May, 2008 相似文献
3.
S. Yu. Zagumennikov 《Bulletin of experimental biology and medicine》1997,123(2):207-208
Prolonged transcutaneous irradiation with helium-neon laser light decreases the transport ability of the popliteal and iliac
lymph nodes. Laser radiation stimulates lymphocytes, predominantly T cells.
Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 123, No. 2, pp. 237–239, February, 1997 相似文献
4.
V. V. Polosukhin 《Bulletin of experimental biology and medicine》1997,123(2):193-198
Structural alterations occurring in blood and lymph microcapillaries during inflammation of the mucous membrane of large bronchi
and morphogenic effects of endobronchial laser therapy are described. The data are interpreted in terms of epitheliostromal
correlations.
Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 123, No. 2, pp. 222–228, February, 1997 相似文献
5.
Petrovich YA Podorozhnaya RP Kichenko SM 《Bulletin of experimental biology and medicine》2005,140(1):102-105
The intensity of 75Se transport in the predominant direction after intraperitoneal injection of [75Se]selenate was compared in 1- and 3-month-old rats receiving common vivarium ration or sucrose diet. The incorporation percent,
blood/liver relative radioactivity, and relative radioactivity difference coefficient were evaluated in the blood and liver.
The dynamics of label incorporation in the blood of rats fed common diets has two peaks (at 1–3 h and 12–24 h) and a drop
at 6 h. Coefficient of difference in 1-month-old rats was characterized by a greater amplitude of fluctuations than in 3-month-old
animals.
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 140, No. 7, pp. 117–120, July, 2005 相似文献
6.
N. I. Rozhkova V. K. Bozhenko A. I. Ploshnitsa A. A. Tashchyan E. A. Kudinova M. L. Mazo 《Bulletin of experimental biology and medicine》2008,145(1):90-92
Comparison of the sensitivity of cytological and molecular genetic methods (19 specimens of lymph nodes from 8 patients with
breast cancer and suspected metastases obtained by transcutaneous fine-needle aspiration biopsy under ultrasound guidance)
showed that molecular genetic and cytological studies produced true results in 95 and 84% specimens, respectively. True-positive
and true-negative results were obtained in 8 and 7 patients, respectively. Expression of cytokeratin 19 was detected in 3
specimens with negative cytological results and confirmed metastases in lymph nodes. Our results indicate that molecular genetic
diagnostic study for lymph node metastases should be used in small amounts of biopsy specimens, presence of marginal metastases
in lymph nodes, and negative results of repeated cytological examination.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 1, pp. 97–99, January, 2008 相似文献
7.
Petrovich YA Podorozhnaya RP Kichenko SM 《Bulletin of experimental biology and medicine》2006,142(5):637-642
The dynamics of fluctuations in the intensity of the blood-bone flow of substances in the predominant and opposite directions
was evaluated using the percent radioactivity difference coefficient and its graphic presentation. The technology of calculating
this coefficient is described.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 11, pp. 585–590, November, 2006 相似文献
8.
Borodin YI Vasilyeva MB Larionov PM Astashov VV Yankaite EV 《Bulletin of experimental biology and medicine》2006,141(4):491-492
Histochemical study of rat pancreas was carried out on days 14 and 30 of acute pancreatitis. The area of the stroma increased
after damage and the area of lymph microcirculatory component increased in comparison with the blood circulation component.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 4, pp. 478–480, April, 2006 相似文献
9.
We studied experimental kinetics of ethomerzol (5-ethoxy-2ethylthiobenzimidazole hydrochloride) distribution in the liver,
brain, kidneys, spleen, heart, skeletal muscles, lungs, adipose tissue, and testes of rats after its single or course administration.
Peculiarities of ethomerzol distribution in various administration regimens were analyzed. Single treatment led to more pronounced
accumulation of the drug in the liver. Study of ethomerzol distribution after course treatment revealed organs and tissues
accumulating the drug (blood, brain, heart, kidneys, lungs, and adipose tissue).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 1, pp. 47–49, January, 2008 相似文献
10.
Ju. I. Borodin Ju. V. Bashkirova M. S. Lyubarsky M. A. Kolpakov 《Bulletin of experimental biology and medicine》2008,146(5):566-568
Using rat model of chronic toxic hepatitis we showed the involvement of the lymph system in the formation of the response
to toxic liver damage consisting in deposition of LPO products in the central lymph and active involvement of antioxidants
in their neutralization with redistribution of ceruloplasmin into lymph vessels against the background of reduced α-tocopherol
content in the central lymph.
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 146, No. 11, pp. 499–502, November, 2008 相似文献
11.
Single injection of mexidol (drug with antioxidant and membranotropic effects) to animals with reactive fever produces a multicomponent
effect on the lymph circulation. The drug increased the number of functioning lymph capillaries and contractile activity of
wall and valvular leaflets in rat small intestinal mesenteric lymphangion, accelerated lymph drainage, thus stimulating lymph
formation and lymph flow.
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 140, No. 10, pp. 433–435, October, 2005 相似文献
12.
Umarova BA Kopylova GN Lelekova TV Bakaeva ZV Goncharova EL Samonina GE 《Bulletin of experimental biology and medicine》2007,144(1):29-32
PGP peptide had a protective effect in contractile dysfunction of the rat mesenteric lymph vessels under conditions of inflammation,
irrespective of the time of its injection (before or after inflammatory agent). The preventive effect of this peptide is largely
determined by its capacity to prevent mast cells activation. PGP injected 2 h after induction of inflammation did not inhibit
secretory activity of mast cells, which suggests other mechanisms of its therapeutic action.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 7, pp. 32–35, July, 2007 相似文献
13.
Borodin YI Maiborodin IV Safina AF Strunkin DN 《Bulletin of experimental biology and medicine》2006,142(6):748-750
Measurements of velocity profiles in arterial microvessels (20–103 μ in diameter) of rat mesentery and m. creamaster showed that bloodflow regimen under natural conditions can be similar to that of Newton fluid or pseudoplastic laminar stream,
which indicates significant fluctuations in blood viscosity.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 12, pp. 707–709, December, 2006 相似文献
14.
Pugovkin AP Evlakhov VI Shalkovskaya LN 《Bulletin of experimental biology and medicine》2006,142(5):548-550
The type and degree of blood pressure changes in cats were studied in acute experiments under conditions of acute hypoxic
hypoxia (40% decrease in oxygen partial pressure). During hypoxia, blood pressure increased in cats with pressor type of the
carotid sinus reflex and decreased in animals with depressor type of this reflex. Our results indicate that the direction
and degree of hypoxic changes in blood pressure in animals coincide with variations in this parameter in response to the carotid
sinus reflex.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 11, pp. 490–493, November, 2006 相似文献
15.
K. A. Triandafilov L. V. Plaksina A. M. Farkhutdinov F. I. Mukhutdinova M. M. Minnebaev 《Bulletin of experimental biology and medicine》2009,147(3):305-307
Experiments on rats showed that low-grade fever is accompanied by a decrease in the central lymph flow rate, which results
from inactivation of lymphangion components in lymphatic microvessels of the small intestine mesentery. Lymph flow rate was
shown to increase during pyrogenal-induced fever, which did not depend on the duration of the disease.
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 147, No. 3, pp. 276–278, March, 2009 相似文献
16.
Acute stress was accompanied by reduction of 11-dehydrocorticosterone to corticosterone in male rats. The reverse reaction
predominated during repeated stress and increased after administration of dehydroepiandrosterone sulfate. Treatment with μ-opioid
receptor antagonist naltrexone in a dose of 0.1 mg/kg 20 min before administration of dehydroepiandrosterone sulfate abolished
this effect.
Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 8, pp. 158–161, August, 2004 相似文献
17.
Zubairova LD Zubairov DM Andrushko IA Svintenok GY Mustafin IG 《Bulletin of experimental biology and medicine》2006,142(5):573-576
The dynamics of microvesicle formation in arterial blood in generalized Schwartzman phenomenon was studied. Successive (with
24-h interval) intravenous injections of endotoxin to rabbits in a dose of 1 mg/kg and 3 mg/kg caused an increase in the content
of microvesicles in the blood, some of them containing ecto-5′-nucleotidase. Biphasic changes in arterial blood clotting time
and erythrocyte hemolysis were observed.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 142, No. 11, pp. 517–520, November, 2006 相似文献
18.
Reactivity of mouse alveolar macrophages by their ability to phagocytize killedSt. aureus bacteria and production of reactive oxygen metabolites (nitro blue tetrazolium test) in response to zymosan administration
was studied under normal conditions and after acute massive blood loss. Zymosan-induced granulomatous inflammation of the
lungs during acute massive blood loss 2-fold inhibited the increase in oxidative metabolism of alveolar macrophages. Suppressed
production of toxic oxygen radicals in alveolar macrophages was accompanied by accelerated recovery of cells on the surface
of the respiratory tract.
Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 9, pp. 257–260, September, 2004 相似文献
19.
Gannushkina IV Konorova IL Koplik EV Antelava AL 《Bulletin of experimental biology and medicine》2006,141(3):288-291
Deltaran decreased the amplitude of EEG slow waves and restored neuronal reactivity after carotid artery occlusion in Wistar
rats sensitive to cerebral ischemia. Deltaran had no effect on local cerebral blood flow. This drug increased blood supply
to a unit of neuronal activity in the brain of intact animals during the acute stage of cerebral ischemia, provided 100% survival
rate of rats with cerebral ischemia, and prevented the development of neurological symptoms in survivors. Animal experiments
proved the possibility of correcting cerebral ischemia with antistress drug Deltaran.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 3, pp. 259–262, March, 2006 相似文献
20.
Comparative study of experimental kinetics of distribution of benzimidazole derivatives (bemithyl, etomerzole, and thietazole)
in organs and tissues was carried out after single and course treatment. The drugs intensely passed into organs and tissues
from the blood after treatment by all protocols. Specific features of drug distribution were detected; for example, splenic
tissue selectively accumulated thietazole during course treatment.
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 146, No. 12, pp. 657–659, December, 2008 相似文献