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1.
Bidirectional regulatory effect of listen injection on sex hormones in senile female patients with coronary heart disease of kidney Deficiency typeon sex hormones in senile female patients with coronary heart disease of kidney Deficiency type
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Objective: To assess the efficacy of Lishen injection (LSI) in treating coronary heart disease (CHD).Methods: The effect of LSI on serum estradiol (E2) testosterone (T) and E2/T ratio in 30 postmenopausal patients with CHD of Kidney Deficiency (KD) were observed.Results: (l) Serum E2 and the E2/T ratio were lower (P < 0.01) in the group of Kidney Yang Deficiency type (KYaDT) and higher (P < 0.01) in the group of Kidney Yin Deficiency type (KYiDT) as compared with normal control. (2) After treatment with LSI the levels of serum E2 and the E2/T ratio were elevated in the KYaDT group (P < 0.01) and lowered in the KYiDT group (P < 0.01). Both approached the normal level (P >0.05). (3) The levels of T in both groups were unaffected (P >0.05) before and after treatment.Conclusion: The imbalance of Kidney-Yin and Kidney-Yang is correlated to the disturbance of sex hormones and LSI could not only regulate the Kidney-Yin and Kidney-Yang, improve the symptoms of KD, but also reverse the disturbance of sex hormone. With a good bidirectional regulatory effect on E2, it is beneficial on balance of sex hormones of both sexes in the inner environment of human body. 相似文献
2.
Qing-Ming Yan Ying Chen Nan Lian Gui-Feng Guo Hong-Ji Mu Guo-Liang Zhao Jun-Gao Cao Ming-Qiong Mai De-Ming Sun 《中国结合医学杂志》1997,3(1):30-34
Objective: To study the links between stagnation of the Liver-Qi and the pathogenesis of ulcerative colitis (UC) were studied clinically and experimentally.Methods: Using the principle of nourishing the Liver in the treated group and invigorating the Spleen in the control group.Results: The effective rate was 96% in the treated group and 82% in the control group, and the difference was significant (P<0.05); the formation rate of E rosettes and the transformation rate of lymphocytes were significantly raised in the two groups compared with the pre-treatment period, and the rate of adjusting dysfunction of vegetative nerve system in the treated group was evidently higher than that in the control group (P < 0.01). The level of intestinal styrenated phenol (SP) and vasoactive intestinal polypeptide (VIP) of UC model were determined in rats, and results showed that the level of SP and VIP significantly increased in the UC model group. They were markedly lowered in the treated group compared with model group (P < 0. 01) and there was significant difference from the control group (P<0.01).Conclusion: Wei Chang Ning , a drug to nourish the Liver, had the action of regulating neurological-endocrinological (gastrointestinal hormone)-immunological system. 相似文献
3.
Studies on Nutritional Effects of Traditional Chinese Tonics with Nutrients Fortification on Pregnantrats
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Studies on Nutritional Effects of Traditional Chinese Tonics with Nutrients Fortification on Pregnant Women and Pregnant Rats... 相似文献
4.
Clinical studies on Liangxue Piyan Granule No. 2 2 in treatment of psoriasisin treatment of psoriasis
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Objective: To evaluate the therapeutic mechanism of Liangxue Piyan Granule No. 2 (LPG, 2 ) on psoriasis.Methods: Ninety six patients with psoriasis were treated with LPG, another 32 patients treated with Fufang Qingdai Capsule (FQC, ) were taken as control; clinical comparison was done with experimental studies.Results: The total effective rate of LPG group was 84.7 %, that of the control 71.9%, there was no significant difference (P<0.05). However, the recurrence rate of LPG group (3.6%) was significantly lower than that of the control (21.7%),P<0.01. Conclusions: LPG could modulate the immune function of the body, by inhibiting directly the proliferation of epidermal cells and the production of interleukin-6. 相似文献
5.
Comparative study of Tiaoxue Yisui recipe with SSL regimen in treating infantile chronic aplastic anemia) with SSL regimen in treating infantile chronic aplastic anemia
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Objective: To find the effective method in treating infantile chronic aplastic anemia (ICAA) by using traditional Chinese medicine (TCM).Methods: Seventy-eight cases of ICAA were observed, 48 in the treated group were treated with Tiaoxue Yisui recipe, and 30 cases in the control group with SSL regimen.Results: The remission rate and total effective rate in the treated group were 52.08% and 81.25% respectively, which were higher than those in the control group (P < 0.05). After one year’s treatment the ratio of hemopoietic and non-hemopoietic cells in the treated group was higher than that in the control group (P < 0.05).Conclusion: Tiaoxue Yisui recipe could improve the living quality of ICAA patients. The therapeutical mechanism of the recipe might be related to its promoting the proliferation of hemopoietic stem cells and regulating the immune function. 相似文献
6.
TraditionalChineseMedicineholdsthatagingiscloselyrelatedwiththefunctionofKidney,thatKidney--Deficiencycouldinducedecrepitude('),andtheagingprocesscouldberetardedbysupplementingKidney.InordertoverifytheeffectofZhuchunPill(ZCP)onaging,fromMay1992toApril1993,agroupofelderlymalepatientswithKidney--YangDeficiencySyndromebutwithoutseriousorganicdiseasewastreatedbyZCP,andthemodernmedicalparametersrelatedwithKidlleyandagingwereobservedandcomparedwiththecontrolgroup.METHODSClinicalMaterials… 相似文献
7.
Study on effect of Baoyuan Qiangshen Capsule No. II on tubular interstitial injury in chronic renal failure patientsCapsule No. II on tubular interstitial injury in chronic renal failure patients
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Pi-jiang Zhu Xian-Jin Wei Wei-bing Zhao Hua Zhao Jun-min Tian Jian-jun Qiu 《中国结合医学杂志》2001,7(3):175-179
Objective: To explore the protective effect of Baoyuan Qiangshen Capsule No. II (BYQS) and its mechanism in treating chronic renal failure (CRF).Methods: Sixty CRF patients were divided into 2 groups randomly, the treated group used BYQS combined with Lotensin and the control group administered with essential amino acid combined with Lotensin. Changes of renal functions and tubular labelled proteins were observed.Results: The markedly effective rate and total effective rate of the treated group were 63.3% and 93.3% respectively, and those of the control group were 30.0% and 56.7% respectively, the effect of the treated group was obviously better than that of the control group (P < 0.01). In the treated group after medication, blood urea nitrogen, serum creatinine and clearance rate of creatinine were improved significantly (P < 0.01), while Tamm-Horfau protein increased significantly (P < 0.01).Conclusion: BYQS could alleviate tubular interstitial injury significantly so as to improve the renal function and enhance the effective rate in treating CRF. 相似文献
8.
Effect of Sanhuang Jiangtang recipe on insulin peripheral resistance in Type II diabetes mellitus) recipe on insulin peripheral resistance in Type II diabetes mellitus
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Zhangzhi Zhu Manqi Xiong Anzhong Lin Wenjiu Cai Zhixi Chen Suiting Shen Xinsheng Long Jun Mi Youya Wu Min He 《中国结合医学杂志》1999,5(1):36-40
Objective: To observe the effect of Sanhuang Jiangtang recipe ( , SHJT) on insulin peripheral resistance in Type II diabetes mellitus (DM).Methods: Ninety-five patients with type II DM were randomly divided into two groups. Fifty-three cases of SHJT group were given decoction and tablets of SHJT orally for 4–6 months. The efficacy was compared with that of 42 cases treated with Glipizide as the control. Before and after treatment standard steamed bread meal test was performed to measure the insulin peripheral sensitivity, insulin release to glucose and insulin sensitivity index.Results: (1) The total effective rates of improving insulin peripheral resistance and reducing blood sugar in SHJT group were 79. 2% and 80.1 %, which was equivalent to levels in the control group, but SHJT recipe was more effective in relieving symptoms of Qi deficiency and signs of blood stasis. (2) In SHJT group, the insulin peripheral sensitivity and insulin sensitivity index were significantly increased (P < 0.05 and 0.01), meanwhile the fasting blood sugar and blood sugar area were reduced (P < 0.05), but the change of insulin release to glucose was blunted. (3)The lowering of blood sugar in SHJT group was significantly negative correlated with the changing of degree of insulin peripheral sensitivity and index of insulin sensitivity (P < 0.01 and 0.05), but not with that of insulin area.Conclusion: It suggested that the treatment of SHJT recipe might decrease insulin peripheral resistance (partial reversal) by means of reducing hyperinsulinemia and improving insulin sensitivity. 相似文献
9.
Clinical observation on effect of Xiaoyu Zhixue Tablet on 104 patients with idiopathic multifocal bleeding and pletelet aggregation defect
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Shen Di Shen Lin Wang Ailian Liu Zhongping Yang Rui Wei Wenning Yang Yan 《中国结合医学杂志》1998,4(4):247-250
Objective: To explore the effect and pharmacological mechanism of Xiaoyu Zhixue Tablet (XZT).Methods: XZT mainly composed of Chinese medical herbs to replenish Qi and remove stasis was used to treat patients with idiopathic multifocal bleeding and platelet aggregation defect. Patients were divided into 2 groups, the TCM group (104 cases) treated with XZT, and the control group (84 cases) with vitamin C, K and P, adrenosin and/or artificial menstruation, for at least 4 months.Results: The hemostatic effective rate was 92.3% in the TCM group and 27.4% in the control group (P< 0.005), the recovery rate of platelet aggregation after 6 months’ therapy was 69.2% and only 1.8% respectively. The difference between the two groups was very significant (P < 0.005).Conclusion: XZT could regulate the hemostatic action and platelet aggregation 相似文献
10.
Objective: To determine the effectiveness of Bailong Tablet and chemotherapy on treatment of moderate and advanced cancers.Methods: The patients were divided randomly into two groups. The treated group (n= 41) was treated with chemotherapy plus Bailong Tablet; and the control group (n= 22) treated with chemotherapy alone. Treatment effectiveness was measured with Karnofsky scores.Results: Karnofsky performance status in the treated group before and after treatment was 66.0 ± 8.7 and 68.0 ± 5.9 respectively, that in the control group was 67. 0 ± 6.8 and 53. 0 ± 7.3 respectively. The completion rate of chemotherapy in the treated group (92.6%, 38/41) was higher than that in control (77.2%, 17/22,P < 0.05). The side-effects caused by chemotherapy in the treated group were lower than that in the control group (P < 0.05). CD3 +, CD4 + and CD4 + /CD8 + ratio were higher in the treated group.Conclusion: Bailong Tablet can enhance the therapeutic effect and reduce the side-effects of chemotherapy. One possible mechanism is the modulation of cellular immune function. 相似文献
11.
Ren-Gao Ye Guo-Hui Ren Hui-Qun Li Xiao-Ping Li Cai-Sheng Lu Yong-Ming Yang Jian-Shi Sun 《中国结合医学杂志》1997,3(1):10-11
Objective: To evaluate the effect of Shentekang Capsule (STKC) combined with peritoneal dialysis (PD) in treating chronic renal failure (CRF).Methods: With single-blind, parallel control and random method, 60 cases of CRF patients were equally divided into 2 groups: (1) STKC group treated with combined therapy of STKC and PD; (2) control group treated with PD alone. The course of treatment were 1~2 months for both groups. Clinical manifestations, blood urea nitrogen, serum creatinine, total protein and hemoglobin were observed before and after the treatment. Results: Blood urea nitrogen decreased in both groups after treatment as compared with that before treatment significantly (P < 0.05), but no obvious difference was found between blood urea nitrogen levels of the two groups (P > 0. 05). However, levels of serum total protein and hemoglobin of the STKC group after treatment were higher than those of the control group (P < 0.01). Clinical manifestation in STKC group also showed more improvement after treatment than that in the control group. Conclusion: STKC could improve nutritional state and quality of CRF patient’s life treated with PD. 相似文献
12.
Clinical Study of Weishu capsule () in treating precancerous lesions of chronic atrophic gastritis) in treating precancerous lesions of chronic atrophic gastritis
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Objective: To explore the therapeutic effect and mechanism of Weishu capsule (WSC), in treating precancerous lesions of chronic atrophic gastritis (CAG).Methods: Seventy-five cases of precancerous lesions of CAG were distributed to two groups randomly, the WSC group (45 patients) treated with WSC taken orally and the Weining granule (WNG) group (30 patients) treated with Weining granule orally. The treatment course of both groups were 6 months. The clinical and pathological effects and the changes in scores of atrophy, intestinal metaplasia (IM) and its subgroups, dysplasia, carcinoembryonic antigen and proliferating cell nuclear antigen expression were observed before and after treatment.Results: The total effective rate was 91% and the effective rate of atrophy, IM, dysplasia in the WSC group were 64%, 67% and 65% respectively, and the respective scores were lowered significantly after treatment. Compared with the WNG group, the difference between the two groups was statistically significant (P < 0.01,P < 0.05). Immunohistochemical test showed that WSC could inhibit the subgroups of IM, circinoembryonic antigen and proliferating cell nuclear antigen expression significantly (P < 0.01).Conclusions: WSC could significantly improve the clinical and pathological changes in the precancerous lesions of CAG. The mechanism might be related to the inducing and promoting effect of WSC on the differentiation and maturity of IM cells and dysplasia cells. WSC could also inhibit and correct the abnormal proliferation of cells. 相似文献
13.
Clinical and experimental study on treatment of infantile autumn diarrhea by retention enema with Qilian Liquid ()
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Objective: To find out the effective treatment for infantile autumn diarrhea (IAD).Methods: Retention enema with Qilian Liquid(QLL) was applied to 106 patients of IAD with positive antigen of rotavirus in stool, and the result in the treated group was compared with that in the control group(82 patients) in aspects of clinical effect, negative conversion rate of rotavirus in stool and change of serum immunoglobulin. Animal experimental study was also conducted.Results: The disappearance time of principal symptoms, negative conversion rate of rotavirus in stool and serum levels of IgA and IgG in the treated group were significantly better than those in the control group (P<0.01,P< 0.05). Experimental study showed that QLL not only has the antiviral effects to stop diarrhea, but also has effects in enhancing immune function and protecting intestinal mucous membrane.Conclusion:Retention enema with QLL is an effective therapy for the treatment of IAD. 相似文献
14.
Clinical and experimental study on treatment of mid-late stage rheumatoid arthritis with Shuguan Granules ())
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Zhou Xueping Zhou Zhongying Jin Miaowen Guo Liwei Fang Taihui Wang Hong Xu Huiqin Wu Mianhua 《中国结合医学杂志》1999,5(3):165-170
Objective: To explore the therapeutic mechanism of Shuguan Granule ( , SGG) in treating mid-late stage rheumatoid arthritis (RA).Methods: Based on the principle of reinforcing Kidney to treat arthritis, removing phlegm to relieve stasis, two SGG, Shuguan Wenjing (SW) and Shuguan Qingluo (SQ) were prepared and used to treat 44 and 43 mid-late stage patients of RA respectively. The clinical results were compared with those of Wangbi Granule. Animal experiments on the effect of these two SGG were conducted.Results: The total effective rate of the SW, SQ and control group was 88.64%, 93.02% and 73.17% respectively. Results of experimental studies in rats with adjuvant-induced arthritis showed that the two SGG obviously raise the level of serum superoxide dismutase, and lowered the levels of serum interleukin-1, plasma prostaglandin E2 and thromboxane B2, as compared with the model group, the difference was significant (P < 0.05,P < 0.01).Conclusion: The two SGG have a comprehensive function of anti-inflammatory, analgesic, antioxidatory, antihypercoagulatory and immunoregulatory effect. 相似文献
15.
Objective: To evaluate the clinical effect of Shenmai injection (SMI) on infantile viral myocarditis.Methods: Fifty patients were treated with SMI combined with routine Western medicines, the effects were observed and compared with those treated with Western medicines alone or compound Salviae liquid.Results: The cardiac function and cellular immunity of patients treated with SMI were significantly improved. The effect of SMI was superior to that of control groups.Conclusion: Using SMI as supplementary treatment in treating infantile viral myocarditis was helpful in recovery of cardiac function and cellular immunity. 相似文献
16.
Objective: To observe the effect of treatment of Mailuoning Injection (MI) for pregnancy induced hypertension (PIH).Methods: Forty six PIH patients in the treated group were treated with intravenous dripping of MI and 40 patients in the control group treated with intravenous dripping of 25% magnesium sulfas.Results: Headache and edema were ameliorated significantly in the MI treated group in comparison with the control (P < 0.05). Both methods could the decrease levels of mean arterial pressure, improve hemorheologic change, and lower the hematocrit, but the effects of the former was better than those of the latter. No difference was found in albuminuria, delivery pattern, postpartum bleeding and neonatal Apgar Score between the two groups.Conclusion: MI could prevent the progress of pathological process of the PIH. The therapeutic mechanism of MI might be relevant to the dilatation of the arteriospasm, improvement of the abnormal microcirculation and hemorheologic character of the patients. 相似文献
17.
Clinical study on treatment of large metastatic cervical lymphnodes of nasopharyngeal carcinoma by Shenlong Liquid in combination with thermotherapy and radiotherapy) in combination with thermotherapy and radiotherapy
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Objective: To observe the clinical treatment of 105 patients of nasopharyngeal carcinoma with large metastatic cervical lymphnodes.Methods: The patients were divided randomly into three groups, 35 for each group. Group A was treated by combined therapy of Shenlong Liquid (SLL) with thermo- and radio-therapy, group B with combined therapy of thermo- and radio-therapy and group C with radiotherapy alone. The clinical conditions of the three groups were similar before treatment.Results: At the end of the treatment, the immediate regression rates of cervical lymphnodes of A, B and C group were 68.57%, 60.00% and 42.86% respectively, and the effect of group A was the best. In comparison of group A and C, the difference was significant (P < 0.05), but the comparison of group B with A, or B with C was insignificant (P >0.05).Conclusions: The combination therapy of SLL with thermo- and radio-therapy was preferable in treating large metastatic lymphnodes, as SLL was beneficial in increasing the sensitivity of tumor to thermotherapy, reducing their side-effect and preventing the hematogenous metastasis. 相似文献
18.
Effect of Xueguantong on plasma endothelin and calcitonin gene-related peptide in quail atherosis modelon plasma endothelin and calcitonin gene-related peptide in quail atherosis model
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Objective: To explore the antiatherogenic mechanism of the action of Xueguantong at molecular level.Methods: After being established by feeding with high fat diet for 12 weeks, the quail atherosis models were given Xueguantong for 30 days. Then, their plasma endothelin and calcitonin gene-related peptide (CGRP) were determined with radioimmunoassay (RIA) and the effects of Xueguantong on plasma endothelin and CGRP in the models were observed.Results: The plasma endothelin increased and CGRP decreased during quail atherosis formation. The plasma endothelin was decreased (P < 0.05) and CGRP increased (P < 0.05) by Xueguantong.Conclusion: One of antiatherogenic mechanisms of Xueguantong was decreasing endothelin and increasing CGRP. 相似文献
19.
Clinical study on Shuxuening combined with antipsychotics in treating chronic schizophreniacombined with antipsychotics in treating chronic schizophrenia
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He-chun Luo Yu-cun Shen Xin Yu Ping Liu Chun-xiang Tan Yu-hua Cui Fan-qiang Meng Xu-dong Yang Jian-cheng Liu Xue-ying Zhao Hong-Wen Zhong Lian-Cheng Zhu Mei-Lan Zhu 《中国结合医学杂志》1997,3(3):191-194
Objective: To make a preliminary evaluation of the clinical efficacy of Shuxuening (SXN).Methods: One hundred and forty-nine chronic schizophrenic patients were divided randomly into the SXN group and the control group in a double-blind research. SXN was given to the SXN group and placebo to the control group, and patients of both groups went on receiving the previous antipsychotic treatment. Brief Psychiatric Rating Scale (BPRS), Scale for Assessment of Negative Symptoms (SANS) and Treatment Emergent Symptoms Scale (TESS) were used to assess the effects of treatment and side effects of the drug. The evaluation was done before and during the 2nd, 4th, 6th, 10th and 12 th weeks in the course of treatment.Results: SXN was effective by BPRS evaluation (P < 0.05), and even the more effective to negative symptoms than positive symptoms by SANS evaluation (P < 0.05). It was safe and with little side effect. In addition, it was found that the incipience of SXN’ s efficacy was somehow related with the course of disease and the daily dosage used.Conclusion: SXN is worthy of further study n the treatment of chronic schizophrenia. 相似文献
20.
Clinical observation on effect of ruangan granule in treating chronic hepatitic liver fibrosis
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