株洲市某医院妇科门诊患者阴道毛滴虫感染情况调查

目的了解医院妇科患者阴道毛滴虫感染情况。方法采用生理盐水直接涂片法检查2008-01/12株洲市三三一医院妇科1 730例门诊患者的阴道分泌物,了解阴道毛滴虫感染情况,对检查结果通过χ2检验进行不同年龄组间感染率的差异分析。结果 1 730例患者中阴道毛滴虫感染率为7.28%(126/1 730);30~39岁年龄组感染率10.08%(49/486),高于其他年龄组,40~49岁年龄组次之(8.01%,31/387)。结论被调查患者阴道毛滴虫感染率较高;30~49岁为滴虫感染高发期。     

中老年阴道炎患者阴道毛滴虫感染特点及耐药性分析

目的 分析中老年阴道炎患者阴道毛滴虫感染特点以及对甲硝唑的耐药性分析,为中老年阴道炎防治提供更多的循证依据。方法 选择本院2021年1月至2022年6月收治的200例中老年阴道炎患者进行研究,采集患者阴道分泌物进行阴道毛滴虫检查,分析阴道毛滴虫感染率,包括患者的年龄、个人卫生习惯、检出季节。获取感染者阴道毛滴虫样本,并进行体外培养。制备甲硝唑梯度浓度板,测定甲硝唑对阴道毛滴虫的最小致死浓度(MLC)。结果 经检测,共有25例存在阴道毛滴虫感染,感染率为12.50%;年龄≤60岁患者阴道毛滴虫感染率为25.00%,明显高于61～80岁和≥81岁的患者,且61～80岁患者感染率高于≥81岁患者,差异均具有统计学意义(P<0.05);定期清洁患者阴道毛滴虫感染率明显低于不经常清洁患者,差异具有统计学意义(P<0.05);春、夏、秋、冬四季毛滴虫感染率比较,差异无统计学意义(P>0.05);25株样品甲硝唑MLC范围在1～300μg/ml,耐药株占比12.00%。结论 中老年阴道炎患者阴道毛滴虫感染率较高,且对甲硝唑已经产生一定的耐药性,临床上应重点关注阴道毛滴虫感染率较高年...     

阴道毛滴虫的研究进展

阴道毛滴虫是寄生在人体阴道及泌尿道的鞭毛虫 ,以性传播为主 ,主要引起滴虫性阴道炎 ,呈全球性分布 ,人群感染比较普遍 ,感染率各地不同 ,以女性 2 0～ 4 0岁年龄组感染率最高 ,平均感染率为 2 8% [1 ]。性罪错妇女、受 HIV感染的妇女和临床上可疑的 STD患者 ,其患病率远高于平均值 ,最高可达4 3.32 % [1～ 3]。很多男性不育症病人的配偶滴虫阳性率也明显高于正常妇女的感染率 [4 ]。1　致病阴道毛滴虫的致病力随虫株及宿主生理状态而变化。 (1)其粘附到人阴道上皮细胞上与之平行 ,根据其外形改变自己的形状 ,然后发挥细胞毒性作用。把…     

医院妇科就诊患者阴道毛滴虫感染状况调查

目的了解医院妇科患者阴道毛滴虫感染状况,指导临床疾病治疗。方法棉签拭子收集妇科患者阴道后穹窿部阴道分泌物,镜检阴道毛滴虫滋养体,统计分析阴道毛滴虫感染情况。结果 471例妇科患者中,阴道毛滴虫感染49例,感染率10.40%。18～岁、20～岁、30～岁、40～岁、50～岁患者感染率分别为5.26%(2/38)、10.62%(12/113)、14.61%(26/178)、7.37%(7/95)和4.26%(2/47)。农民、矿工、公务员、教师、服务业、无固定职业者感染率分别为16.22%(18/111)、12.90%(12/93)、5.13%(4/78)、3.77%(2/53)、11.11%(8/72)和7.81%(5/64)。使用避孕套、口服避孕药、无避孕措施患者分别感染22、16和11例,感染率为6.90%(22/319)、15.84%(16/101)和21.57%(11/51),无避孕措施者感染率最高,差异有统计学意义(χ2=7.649 1,P=0.005 7)。从不、偶尔、经常使用公共马桶者感染率分别为7.14%(11/154)、10.09%(22/218)和16.16%(16/99);从不、偶尔、经常共用浴巾浴衣者感染率分别为6.12%(15/245)、11.51%(16/139)和20.69%(18/87);从不、偶尔、经常混用洗脚洗会阴盆者感染率分别为4.14%(13/314)、19.44%(14/72)和25.88%(22/85)。经常使用公共马桶、经常共用浴巾浴衣者和经常混用洗脚洗会阴盆者感染率高于其他患者,差异均有统计学意义(χ2=4.4588,12.1131,26.6606,P均0.05)。结论阴道毛滴虫感染妇科就诊患者以30～岁、农民、无避孕措施的患者居多,养成良好的卫生习惯可减少感染发生。     

农村已婚妇女阴道毛滴虫感染现状及危险因素调查

目的了解农村已婚妇女阴道毛滴虫感染现状及影响因素，为实施干预措施提供依据。方法按经济水平分层整群随机抽样，以抽样村60岁以下已婚妇女为调查对象，进行阴道毛滴虫感染流行病学基线调查，同时采取阴道后穹窿阴道分泌物，悬滴法镜检阴道毛滴虫。结果在5781名被调查者中，共检出阴道毛滴虫感染者212例，总感染率3．67％。影响农村已婚妇女阴道毛滴虫感染的主要因素为：洁阴用具是否专用、每周清洗会阴次数、性病知识知晓水平。结论农村已婚妇女阴道毛滴虫感染与性病知识和洁阴习惯有关。     

唐山市不同职业人群面部蠕形螨感染情况调查及影响因素分析

目的调查唐山市不同职业人群(在校生、银行职员、化妆品销售员)面部蠕形螨感染情况,并探讨蠕形螨感染相关因素。方法采用挤压法和透明胶带纸粘贴法,对鼻尖和鼻翼侧部进行蠕形螨的检查,同时调查受检者的年龄、性别等基本情况。结果共调查825人,面部蠕形螨感染244人,感染率29.58%,其中男性感染率为28.90%,女性感染率为30.08%;学生感染率为27.01%(其中小学生8.07%,初中生20.11%,高中生25.73%,大学生52.20%),银行职员为37.86%,化妆品销售员为37.00%;皮脂型蠕形螨感染者占8.61%,毛囊型占79.92%,混合型占11.47%;油性皮肤者感染率为42.91%,干燥型皮肤者感染率为24.37%,混合型皮肤者感染率为21.82%;患有酒糟鼻、痤疮等面部疾病者感染率为82.61%,高于无面部疾病者28.05%(χ2=31.98,P<0.05);居住环境潮湿的受检者感染率为51.75%,高于居住环境干燥者17.81%(χ2=103.31,P<0.05)。结论唐山市不同职业人群面部蠕形螨感染率不同。蠕形螨感染与年龄、性别、职业、皮肤类型、面部疾病、生活条件、居住(工作)环境及个人卫生习惯等有关。     

阴道毛滴虫双链RNA病毒感染及其对甲硝唑耐药性的影响

目的调查河南地区阴道毛滴虫临床分离株阴道毛滴虫病毒感染情况,探索病毒感染对阴道毛滴虫甲硝唑耐药性的影响。方法 TYM(trypticase-yeast extract-maltose)无菌培养基培养阴道毛滴虫临床分离株,达到纯培养后提取虫体总核酸(DNA和RNA),进行1%琼脂糖凝胶电泳分析;连续稀释法测量每株虫体的甲硝唑最小致死浓度。结果对30株阴道毛滴虫总核酸进行电泳,其中6株有5.5 kb双链RNA病毒带,病毒感染率为20.0%。阴道毛滴虫病毒阴性组甲硝唑最小致死浓度为(24.27±20.899)μg/ml,病毒阳性组为(5.68±3.588)μg/ml,差异有统计学意义(t=2.143,P<0.05)。结论河南地区阴道毛滴虫临床分离株中检测到阴道毛滴虫病毒,无阴道毛滴虫病毒寄生的虫体易发生甲硝唑抵抗。     

4860名妇女阴道毛滴虫感染调查

阴道毛滴虫引起的阴道炎、尿道炎，是我国妇女常见病之一［１］，严重危害广大妇女身心健康，已被社会广泛重视，并作为妇女病普查的重要内容之一。现将我县妇女阴道毛滴虫感染情况报道如下。调查对象与方法按东南西北中方位，全县选５个点检查＞１６岁育龄妇女。调查参照赵慰先主编《人体寄生虫学》阴道毛滴虫检查方法［２］。结　果本次共调查＞１６岁育龄妇女４８６０人，其中阴道毛滴虫阳性５４５例，阳性率１１．２１％。检查已婚妇女４１２４人，阴道毛滴虫感染４８２例，感染率１１．６８％，未婚妇女感染率８．５６％（６３／７３６…     

2015年贵州省人体华支睾吸虫感染现状调查分析

为了解2015年贵州省人体华支睾吸虫感染情况,按照《全国人体重点寄生虫病现状调查方案》和实施细则相关要求,采用分层整群随机抽样的方法从全省16个县(市、区)抽取30个农村和5个城镇为调查点,每个调查点检测不少于250人。采用改良加藤厚涂片法(一粪二检)对被调查者粪样进行检测,镜检华支睾吸虫卵及其他人体重点寄生虫虫卵并计数,同时采集被调查者一般情况信息。结果显示,全省共调查8 838人,华支睾吸虫感染37例,感染率0.42%(37/8 838),均属轻度感染。男、女华支睾吸虫感染率分别为0.50%(22/4 375)和0.34%(15/4 463)。36例感染者集中于黔东南州,1例在六盘水市,地区间差异有统计学意义(P <0.01)。农村调查点7 572人,感染率为0.04%(3/7 572);城镇调查点1 266人,感染率为2.69%(34/1 266),差异有统计学意义(P <0.01)。黔东南州城镇调查点中,榕江县(镇区)感染率达11.90%(30/252),高于凯里市(城区)(1.60%, 4/250)(P <0.01)。37例华支睾吸虫感染者中,仅1例合并蛔虫感染。各年龄组中以11~20岁组感染率最高,为0.97%;文化程度以高中、中专学历人群感染率最高,为3.14%;职业以工人、干部等上班族最高,为2.36%,不同年龄、文化程度、职业人群差异均有统计学意义(P <0.01)。贵州省黔东南州仍是华支睾吸虫病的重点流行区,需扩大城镇调查点进一步摸清华支睾吸虫感染流行状况。     

非淋菌性尿道炎患者支原体合并阴道毛滴虫感染情况的调查分析

对1744例非淋菌性尿道炎（NGU）患者中段尿（男性）和阴道分泌物（女性）进行支原体培养、鉴定，并将该分泌物置显微镜下检查阴道毛滴虫。发现1744例NGU患者中，支原体、阴道毛滴虫、支原体和阴道毛滴虫混合感染率依次为36．35％、12．79％、12．44％。在支原体和毛滴虫混合感染217例中，男39．17％，女60．83％；不同年龄组中，以20～40岁年龄段感染率最高。认为本地区NGU患者中，混合感染现象较为多见，并以女性居多，好发于20～40年龄段，应引起临床重视。     

青少年高血压的研究进展

随着人们生活和行为方式的改变,高血压发病明显呈年轻化趋势。在青少年时期识别高血压病高危人群有助于早期进行有效干预和治疗,降低未来高血压的发生率及其严重性。现试从青少年高血压的诊断、发病因素、特点、治疗策略等方面的研究进展作一综述。     

Morbidity in cardiovascular diseases in immigrants in Sweden

INTRODUCTION: Although immigration to Sweden has increased in the last few decades, the incidence rates of cardiovascular disease and coronary heart disease in immigrants are unknown. The aim of the present study is to estimate whether place of birth affects the incidence rates of cardiovascular disease and coronary heart disease. MATERIAL AND METHODS: The study was designed as a follow-up study on morbidity in cardiovascular disease and coronary heart disease between 1 January 1997 and 31 December 1998, including three and a half million persons with age range 35-64 years, of whom 550 000 were born abroad, from the database MigMed consisting of the whole Swedish population. Incidence rates and relative risks were estimated by indirect standardization and a proportional hazard model. RESULTS: The age-adjusted risk of coronary heart disease was higher in most foreign-born groups than in Swedes. For example, in nine of 12 male groups, the relative risks varied between 1.1 and 2.2, and in seven of 12 female groups, the relative risks varied between 1.4 and 2.5. When also adjusting for level of education and employment status, the risks were still high, but on a lower level. CONCLUSIONS: Foreign-born people possess an over-risk of cardiovascular or coronary heart disease(CVD/CHD) compared with Swedish-born persons, also when level of education and employment status are taken into account.     

C·肉毒杀鼠素(冻干剂)应用研究

目的为研究C·肉毒杀鼠索对杀灭达乌尔黄鼠(简称黄鼠)的大面积应用情况和对家畜、家禽的毒害作用,进行了C·肉毒杀鼠素的应用研究.方法大面积投毒采用ES-2药饵撒播机[1],间隔约80m进行条投.羊、鸡采用直接灌胃.结果大面积应用的灭鼠率为83.72%.对羊、鸡最高剂量分别为500万MLD、150万MLD,均未出现中毒现象.结论 C·肉毒杀鼠素是较为理想的草原大面积杀灭黄鼠的理想、首选药物.     

Pulmonary sporotrichosis in Oklahoma in susceptibilities in vitro

Six cases of pulmonary sporotichosis were observed in 2 institutions in Oklahoma City, Okla. Three of the patients were treated with iodides with or without surgery. Although one patient required a second course of iodides, the patients have remained well after at least 34 months of follow-up. Three patients treated with amphotericin B, single course as well as multiple courses, and other antifungal agents (hydroxystilbamidine and miconazole) have all relapsed. These cases and a reviewed of more than 40 cases of pulmonary sporotrichosis susceptibilities of Sporothrix schenckii that we observed in vitro suggest that amphotericin B is not an effective agent for the treatment of pulmonary sporotrichosis. It is our opinion that the treatment of choice for pulmonary sporotrichosis is a supersaturated solution of potassium iodide. If the patient is allergic to the medication or fails to respond, then a combination of amphotericin B plus flucytosine may be tried.     

Differences in outcome in primary angioplasty in women.

BACKGROUND: In acute myocardial infarction (AMI), primary percutaneous transluminal coronary angioplasty (PTCA) has proved to be the best therapeutic approach. Several factors have been associated with worse outcome in AMI in females. Are there differences in outcome in women undergoing PTCA for AMI? AIM: To evaluate gender influence on clinical outcome and in-hospital mortality in patients with AMI who undergo primary percutaneous interventions. METHODS: We studied 245 consecutive patients (72 women, 29.4 %), who underwent primary PTCA between January 2000 and December 2001. The following parameters were analyzed: risk factors for coronary artery disease including hypertension, diabetes, smoking, hypercholesterolemia and family history, previous AMI, PTCA or angina, pain-to-balloon time, extent of coronary disease and outcome. RESULTS: Female patients were older (67.9+/-11.6 vs. 59.6+/-13; p < 0.001) with a higher prevalence of hypertension (65.3 % vs. 47.4 %; p < 0.05) and angina (29.0 % vs. 16.0 %; p < 0.05) and lower prevalence of smoking (27.8 % vs. 54.3 %; p < 0.001). Pain-to-balloon time was longer in women (6.8+/-4.1 vs. 5.4+/-3.7 hours; p < 0.05). Extent of coronary disease was similar in both groups. Glycoprotein IIb/IIIa inhibitors were used in 84.7 % of women and 90.8 % of men. The frequency of hemorrhagic complications (5.6 % vs. 5.2 %) and arrhythmias (15.3 % vs. 10.4%) and in-hospital mortality (9.7 6.4 %) were higher in females, although without statistical significance (p = NS). Hospitalization time was similar in both groups. CONCLUSIONS: Despite the growing awareness of a gender bias in therapeutic approaches to AMI, there are still some differences in outcome, with a trend towards higher mortality rates in women. Older age and longer pain-to-balloon time could account for this.