MR arthrography of anterior cruciate ligament reconstruction grafts

OBJECTIVE: Our objective was to determine the accuracy of MR arthrography for identification of tears of anterior cruciate ligament reconstruction grafts and for detection of localized anterior arthrofibrosis and impingement. MATERIALS AND METHODS: We retrospectively identified 27 patients (mean age, 31 years; range, 18-45 years) with anterior cruciate ligament reconstruction who had undergone MR arthrography followed by arthroscopy within 1 year. Three radiologists independently reviewed the MR arthrograms for the presence or absence of graft tear, localized anterior arthrofibrosis, and impingement. RESULTS: Graft tears were identified with 100% sensitivity by all three reviewers with specificities of 100%, 89%, and 94%. Localized anterior arthrofibrosis was identified with 100% sensitivity by all reviewers, with specificities of 79%, 71%, and 38%. Impingement was detected with sensitivities and specificities of 83% and 100%, 83% and 52%, and 33% and 90% by the three reviewers, respectively. Interobserver agreement was almost perfect for detection of graft tear (kappa = 0.83, 0.92, and 0.83), was fair to moderate for detection of localized anterior arthrofibrosis (kappa = 0.50, 0.32, and 0.22), and was slight to fair for detection of impingement (kappa = 0.40, 0.08, and 0.35). CONCLUSION: MR arthrography can accurately depict the presence of anterior cruciate ligament graft tears. Localized anterior arthrofibrosis and graft impingement were less accurately detected and showed greater observer variability.     

Acute anterior cruciate ligament stump entrapment in anterior cruciate ligament tears: MR imaging appearance

PURPOSE: To describe the magnetic resonance (MR) imaging appearance of anterior cruciate ligament (ACL) stump entrapment in patients who presented with decreased knee extension after rupturing the ACL. MATERIALS AND METHODS: MR images in 15 patients who had presented with a block to terminal knee extension after sustaining an ACL tear were retrospectively reviewed. The MR imaging appearances of entrapped ACL stumps were defined and correlated with arthroscopic and histologic findings. RESULTS: The entrapped ACL stumps had two distinct appearances. Type 1 stumps (n = 11) were characterized by a nodular mass located at the anterior aspect of the intercondylar notch, interposed between the lateral femoral condyle and tibia. Type 2 stumps (n = 4) were characterized by a tonguelike free end and angulation of the stump. Histologic evaluation of the resected specimens showed distorted ACL fibers intermixed with variable fibrosis and inflammation. CONCLUSION: Entrapment of an ACL stump can limit knee extension. The two observed appearances of entrapped ACL stumps likely represent two points along a spectrum of appearances, which possibly includes the cyclops lesion.     

MR imaging of anterior cruciate ligament repair

Magnetic resonance (MR) imaging is an accurate means of analyzing disruptions of the native anterior cruciate ligament (ACL). Various techniques may be used to repair a disrupted ACL. A common repair is the MacIntosh lateral-substitution over-the-top repair in which a strip of fascia lata from the iliotibial band is used as a "neoligament." The results of 27 MR examinations of 17 athletes with this repair were analyzed to determine the appearance of the neoligament on MR. Thirteen of the 17 patients had returned to full athletic activity and four were capable of strenuous activity. Examinations were made at both 0.5 and 1.5 T in varied extents of external rotation from 0 to 20 degrees, and at variable time intervals after surgery from 1 to nearly 40 months. Only two patients clinically required postrepair arthroscopy, but both had normal repairs. Neoligaments were classified as well-defined (n = 6 studies), ill-defined (n = 10), and not discernible (n = 11), based on clarity of appearance. Reasons for this variable appearance include the variable presence of fibrous and fatty tissue investing the neoligament. We conclude that the normal neoligament, unlike the normal active ACL, has a variable appearance, including nonvisualization on MR and that criteria used in evaluating the native ligament will be inadequate to assess the repair.     

The normal anterior cruciate ligament as a model for tensioning strategies in anterior cruciate ligament grafts

BACKGROUND: There is some confusion about the relationship between the tension placed on the graft and the joint position used in the fixation of anterior cruciate ligament grafts. This is because of deficiency in accurate basic science about this important interaction in the normal and reconstructed anterior cruciate ligament. HYPOTHESIS: If the normal femoral attachment of the anterior cruciate ligament can be preserved and the tibial insertion isolated and tested, an accurate force-flexion curve of the human anterior cruciate ligament can be mapped out and used as a standard for proper graft tensioning protocols in anterior cruciate ligament reconstruction. STUDY DESIGN: Controlled laboratory study. METHODS: In 10 fresh-frozen human cadaveric knees, an isolated bone plug containing the tibial anterior cruciate ligament insertion was connected with a custom-made tensiometer. The knees were moved through the whole range of motion; the starting point chosen was an anterior cruciate ligament tension of 10 N, which was applied at 10 degrees of knee flexion and resulted in a baseline curve. This curve was compared with the results recorded when the starting point was below the baseline curve, similar to, or above it. RESULTS: The anterior cruciate ligament showed low tension close to slackness in midflexion after starting with 10 N at 10 degrees of flexion. Starting points below the baseline curve shifted the whole curve downward; those above the baseline curve increased the force in the anterior cruciate ligament, resulting in a tight anterior cruciate ligament in midflexion. CLINICAL RELEVANCE: The normal anterior cruciate ligament shows a physiological laxity in midflexion. This study gives guidelines for tensioning protocols in anterior cruciate ligament grafts to replicate the force-flexion curve characteristics of the normal anterior cruciate ligament.     

Complications of anterior cruciate ligament reconstruction: MR imaging

Arthroscopic reconstruction of the anterior cruciate ligament (ACL) using autografts or allografts is being performed with increasing frequency, particularly in young athletes. Although the procedure is generally well tolerated, with good success rates, early and late complications have been documented. As clinical manifestations of graft complications are often non-specific and plain radiographs cannot directly visualize the graft and the adjacent soft tissues, MR imaging has a definite role in the diagnosis of complications after ACL reconstruction and may direct subsequent therapeutic management. Our purpose is to review the normal MR imaging of the ACL graft and present the MR imaging findings of a wide spectrum of complications after ACL reconstruction, such as graft impingement, graft rupture, cystic degeneration of the graft, postoperative infection of the knee, diffuse and localized (i.e., cyclops lesion) arthrofibrosis, and associated donor site abnormalities. Awareness of the MR imaging findings of complications as well as the normal appearances of the normal ACL graft is essential for correct interpretation. Electronic Publication     

Native anterior cruciate ligament obliquity versus anterior cruciate ligament graft obliquity: an observational study using navigated measurements

BACKGROUND: The goal of anterior cruciate ligament reconstruction is to attain a graft that closely resembles the native anterior cruciate ligament anatomy. By reconstructing the original anatomy, one hopes to eliminate issues related to graft elongation, impingement, and excessive tension while achieving ideal knee kinematics. HYPOTHESIS: Clinical grafts placed using the transtibial technique will differ in the sagittal and coronal planes when compared with obliquity of the anatomic anterior cruciate ligament. STUDY DESIGN: Controlled laboratory study/case series; Level of evidence, 4. METHODS: With the assistance of computer navigation, our study compared the anterior cruciate ligament orientation of 5 cadaver knees with 12 clinical anterior cruciate ligament-reconstructed knees using the transtibial technique. Results: Clinical graft obliquity differed from the anatomic anterior cruciate ligament in all flexion angles: 0 degrees, 30 degrees, 60 degrees, and 90 degrees. In the sagittal plane, the clinical graft obliquity differed from the anatomic anterior cruciate ligament by 13.6 degrees, 12.7 degrees, 16.7 degrees, and 17 degrees, respectively. In the coronal plane, the clinical graft obliquity differed from the anatomic anterior cruciate ligament by 4.9 degrees, 7.6 degrees, 8.9 degrees, and 12.7 degrees, respectively. Paired t tests demonstrated that the difference between the clinical and anatomic anterior cruciate ligament was significant (P <.05), except in the coronal plane at 0 degrees of flexion. In spite of this, all patients demonstrated a negative pivot shift and Lachman at the conclusion of their reconstructions and at 6-month follow-up. CONCLUSION: The sagittal and coronal plane obliquity of well-functioning grafts placed using the transtibial technique were more vertical than anatomic fibers. CLINICAL RELEVANCE: Graft obliquity, in both the coronal and sagittal plane, may be an important means to target appropriate anterior cruciate ligament graft position and can be monitored using surgical navigation systems.     

MR imaging of anterior cruciate ligament reconstruction graft

OBJECTIVE. The objective was to determine the MR imaging findings that differentiate intact anterior cruciate ligament reconstruction graft, partial-thickness tear, and full-thickness tear, using arthroscopy as the gold standard. MATERIALS AND METHODS. Sixteen consecutive MR imaging examinations were retrospectively and independently evaluated by two musculoskeletal radiologists for primary signs (graft signal, orientation, fiber continuity, complete discontinuity, and thickness) and secondary signs (anterior tibial translation, uncovered posterior horn lateral meniscus, posterior cruciate ligament hyperbuckling, and abnormal posterior cruciate ligament line) of anterior cruciate ligament reconstruction graft tear in 15 patients with follow-up arthroscopy. Results were compared with arthroscopy, and both receiver operating characteristic curves and kappa values for interobserver variability were calculated. RESULTS. Arthroscopy revealed four full-thickness graft tears, seven partial-thickness tears, and five intact grafts. Of the primary signs, graft fiber continuity in the coronal plane and 100% graft thickness in the sagittal or coronal plane were most valuable in excluding full-thickness tear. Complete discontinuous graft in the coronal plane also was valuable in diagnosis of full-thickness tear. Of the secondary signs, anterior tibial translation and uncovered posterior horn lateral meniscus assisted in differentiating graft tear (partial or full thickness) from intact graft. The other primary and secondary signs were less valuable. Kappa values were highest for graft fiber continuity and graft discontinuity in the coronal plane. CONCLUSION. Full-thickness anterior cruciate ligament graft tear can be differentiated from partial-thickness tear or intact graft by evaluating for graft fiber continuity (coronal plane), complete graft discontinuity (coronal plane), and graft thickness (coronal or sagittal plane).     

MR imaging of anterior cruciate ligament reconstruction poor outcomes

Purpose

Is to study the diagnostic value of MR imaging in assessment of poor outcomes of ACL reconstruction using second look arthroscopy of the knee as a gold standard.

Patients and methods

51 patients were included in this study who did ACL reconstruction followed by MRI and second look arthroscopy. Arthroscopy study was performed within 7–15 days from MR examination. The time interval between ACL reconstruction and MRI examination was 10 months to 9 years. MR images were evaluated for; (1) ACL graft failure assessing the primary and secondary signs, (2) Tibial and femoral tunnel location, and (3) Complication of ACL graft reconstruction. MR imaging results were compared with the arthroscopic results.

Results

Second look arthroscopy revealed 23 patients with full- thickness ACL graft tears, 17 partial -thickness ACL graft tears and 11 intact ACL grafts. Complete ACL graft discontinuity, focal ACL graft thinning and preserved 100% graft thickness were the most valuable primary MRI signs in the diagnosis of full thickness ACL graft tear, partial tear and intact graft respectively.

Conclusion

We found MR imaging to be reliable for the evaluation of ACL graft poor outcomes including graft failure and complications.     

Intra-articular remodelling of hamstring tendon grafts after anterior cruciate ligament reconstruction

Purpose

A summary is provided on the existing knowledge about the specific healing phases of the intra-articular hamstring tendon graft used for ACL reconstruction. Differences between human and animal in vivo studies are explained, and implications for the postoperative time period are laid out.

Methods

A systematic review of the existing literature was performed on the topic of tendon remodelling of hamstring grafts in ACL reconstruction using Medline database. Publications between 1982 and 2012 were included. Special focus was directed on in vivo human and animal studies analysing intra-articular free tendon graft remodelling.

Results

Animal and human in vitro and vivo researches have demonstrated three characteristic stages of graft healing after ACL reconstruction: an early graft healing phase with central graft necrosis and hypocellularity and no detectable revascularization of the graft tissue, followed by a phase of proliferation, the time of most intensive remodelling and revascularization and finally, a ligamentization phase with characteristic restructuring of the graft towards the properties of the intact ACL. However, a full restoration of either the biological or biomechanical properties of the intact ACL is not achieved.

Conclusion

Significant knowledge on human cruciate ligament remodelling has been added in the understanding of the processes during the course of graft healing. Most importantly, the remodelling process in humans is prolonged compared to animal studies. While today´s rehabilitation protocols are often extrapolated from findings of animal in vivo healing studies, current findings of human in vivo healing studies might require new post-operative regimens following hamstring ACL reconstruction.     

膝关节前交叉韧带撕裂MRI多征象分析

前交叉韧带（anterior cruciate ligament,ACL）起自股骨外侧髁内侧面的后部,由外上向内下旋转走行,止于胫骨髁间棘略前外侧。ACL的作用主要防止胫骨向前移位和内旋,并限制膝关节过伸和股骨内旋,是维持膝关节稳定的主要结构之一。ACL撕裂是膝关节创伤常见的并发症,MRI能直接显示撕裂的ACL,并能显示关节其他结构的继发改变,是检查ACL撕裂准确和有效的非侵蚀性方法。     

Improperly placed anterior cruciate ligament grafts: correlation between radiological parameters and clinical results

Despite increasing knowledge on knee biomechanics and refined operative techniques, an increasing number of patients are being seen with failed anterior cruciate ligament (ACL) reconstruction. Failure of the reconstruction and further damage to the knee are correlated with improper placement of the graft, which interferes with graft biology and biomechanical demands. Between 1994 and 1995, 63 patients with improperly placed ACL grafts were referred to our institution because of persistent knee instability and pain. A method for analysis of the femoral drill hole on radiography was developed. Before reoperation the radiograph was evaluated by our method, noting the clinical aspects according to the recommendations of the International Knee Documentation Committee (IKDC). The femoral placement of the ACL graft could easily be defined on the lateral and anteroposterior tunnel radiography. The most common error was a femoral placement anterior to the anatomical insertion of the ACL. A significant correlation (P < 0.05) was found between femoral placement of the graft in the sagittal plane and clinical results: the IKDC score declined with increasing distance of the graft from the most isometric bundle of the ACL in the anteroposterior direction. Received: 26 August 1998 Accepted: 17 April 2000     

Posterior cruciate ligament: MR imaging

The authors reviewed 610 consecutive magnetic resonance (MR) examinations of patients with suspected internal derangements of the knee, paying special attention to the posterior cruciate ligament (PCL). The normal PCL shows a low MR signal intensity and an arcuate shape. An accessory anterior or posterior meniscofemoral ligament was identified in 58.5% of examinations. Among 202 patients who underwent arthroscopy or arthrotomy, MR imaging depicted 11 PCL injuries: eight complete or incomplete ligament disruptions and three avulsions. All were confirmed by means of arthroscopy or arthrotomy. MR findings of PCL injury were anatomic disruption, increased signal intensity in the ligament, and redundancy of an avulsed ligament. Of the 11 PCL injuries, four were not detected at initial clinical examination. In none of the 202 patients in whom arthroscopy or surgery was performed was an abnormal PCL identified in the presence of a normal MR examination. MR imaging is a reliable method for the detection of PCL injuries.     

三维MR影像对前交叉韧带损伤诊断价值的研究

目的 比较常规2D及3D超长回波链采集FSE序列(3D Cube T2WI) MRI对前交叉韧带(ACL)损伤的诊断价值.方法 40例膝关节外伤患者先后行常规2D MR及3D Cube T2WI MR检查并分别作出ACL损伤的诊断,包括ACL完整、部分撕裂及完全撕裂.以关节镜检查结果作为ACL损伤的金标准.应用ROC法计算2种影像检查对ACL部分撕裂及完全撕裂诊断的曲线下面积(AUC)值并应用Hanley&McNeil检验比较两者在统计学上的差异.结果 40例经关节镜证实的膝关节损伤患者中,ACL完整者16例,双束完全撕裂为12例,部分撕裂者为12例.对ACL完全撕裂,2D MR的AUC值为0.839,3D Cube的AUC值为0.923,两者差异无统计学意义(Z=1.245,P=0.213);而对于ACL部分撕裂,2D MR的AUC值为0.643,3D Cube的AUC值为0.881,两者差异有统计学意义(Z =2.384,P=0.017).结论 常规2D MR及3D Cube MR对ACL完全断裂诊断效力无差异,3D Cube MR对于ACL部分损伤诊断效力优于常规2D MR.     

A new interference nail fixation for anterior cruciate ligament soft tissue grafts

We present a new device for femoral and tibial fixation in anterior cruciate ligament reconstruction using soft tissue. We evaluated the method biomechanically in pullout tests using human cadaver knee joints. Fixation strengths ranged from 300 ± 60 to 600 ± 50 N (mean 400 ± 50 N). This corresponds to loads in the graft during aggressive rehabilitation although cadaveric specimens were used. With respect to primary fixation strength this implant is a reasonable alternative for anterior cruciate ligament graft fixation. Received: 6 October 1999 Accepted: 5 March 2000     

A biomechanical evaluation of transcondylar femoral fixation of anterior cruciate ligament grafts

BACKGROUND: Interference screw fixation of the graft in anterior cruciate ligament reconstruction is considered the gold standard, but limited clinical experience suggests that transcondylar fixation is equally effective. PURPOSE: To compare transcondylar and interference screw fixation. STUDY DESIGN: Ex vivo biomechanical study. METHODS: Twenty pairs of unembalmed knees underwent anterior cruciate ligament reconstruction with patellar tendon autografts. In 1 knee of each pair, the bone plug was stabilized in the femoral tunnel with standard interference screws; in the other knee, transcondylar screws were used. Testing to failure occurred immediately or after 1000 cycles of sinusoidal loading (30 to 150 N) (20 paired reconstructions each). Fixation stiffness, strength, graft creep, displacement amplitude, and change in amplitude were measured and compared (repeated measures anaylsis of variance with Tukey test; P <.05). RESULTS: There was no significant difference in acute strength, maximum load within 3 mm, or stiffness between transcondylar fixation (410 +/- 164 N, 183 +/- 93 N, and 49.6 +/- 28 N/mm, respectively) and interference fixation (497 +/- 216 N, 206 +/- 115 N, and 61 +/- 37.8 N/mm, respectively). Similarly, there was no significant difference in cyclic strength, maximum load within 3 mm, or stiffness between transcondylar fixation (496 +/- 214 N, 357 +/- 82.9 N, and 110 +/- 27.4 N/mm, respectively) and interference fixation (552 +/- 233 N, 357 +/- 76.2 N, and 112 +/- 26.8 N/mm, respectively). Predominant modes of failure were bone plug pullout (transcondylar fixation) and tendon failure or bone plug fracture (interference fixation). CONCLUSIONS: Transcondylar screw fixation of the patellar tendon autograft into the femoral tunnel performed mechanically as well as interference screw fixation. CLINICAL RELEVANCE: The results suggest that transcondylar and interference screws provide similar fixation for anterior cruciate ligament reconstruction.     

Effect of joint position and ligament tension on the MR signal intensity of the cruciate ligaments of the knee

Six cadaveric lower extremities were imaged with T1-weighted spin-echo pulse sequences with the knees extended and flexed to 90°. Magnetic resonance signal intensities of the anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) were compared. Changing from extension to flexion resulted in decreased signal intensity in six of six ACLs and five of six PCLs. Two of the knees were then imaged with and without tension applied to the ACL. Both specimens showed a decrease in signal intensity with tension, followed by an increase in signal intensity with release of the tension. Finally, in three of the limbs the ACL was surgically reconstructed and then imaged with and without tension applied to the tension graft. Signal intensity decreased with tension and increased with release of the tension in all three specimens. Thus, joint position and changes in ligament tension affect the signal intensity of the ACL and PCL, generally resulting in a signal intensity decrease with tension.     

MRI analysis of single-, double-, and triple-bundle anterior cruciate ligament grafts

Purpose

The purpose of the study was to evaluate the entire course of ACL grafts on coronal oblique MR images, focusing on differences in graft morphology and graft-to-tunnel healing among single-bundle (SB), double-bundle (DB), and triple-bundle (TB) reconstructions.

Methods

Eighty-three patients underwent anatomical ACL reconstruction using the semitendinosus tendon. SB reconstruction was performed on 20 patients, DB on 29 patients, and TB on 34 patients. The anteromedial-bundle (AMB) and posterolateral-bundle (PLB) images were extracted from coronal oblique images of grafts at 6 months to visualize their entire course. Signal intensity of grafts was measured independently in three regions: (1) intra-femoral tunnel region, (2) intra-articular region, and (3) intra-tibial tunnel region, followed by calculation of the signal-to-noise quotient (SNQ). To evaluate graft-to-tunnel healing, T2-weighted images were examined for the presence of a high signal-intensity lesion between the graft and bone tunnel around the tunnel aperture.

Results

AMB images showed that SB graft was thick throughout the entire course, while DB graft was thinner than SB graft. TB graft showed a fan shape approaching the tibial tunnels. The SNQ in the femoral tunnel of SB graft was significantly lower than in the DB and TB grafts. High signal-intensity lesions were frequently observed around the femoral tunnel aperture in PLB images of DB and TB grafts compared to SB grafts.

Conclusion

Gross morphology of TB grafts resembled that of the natural ACL. However, the graft-to-tunnel healing around the femoral tunnel seemed to be insufficient in PLB images of DB and TB compared to SB grafts.

Level of evidence

III.