龙虎交战针刺法治疗脑卒中后肩手综合征的远期疗效及对血清CGRP、BK水平的影响

目的:探讨龙虎交战针刺法治疗脑卒中后肩手综合征的远期疗效及对降钙素缓激肽(CGRP)、缓激肽(BK)水平的影响。方法:选取2022年2月—2023年2月黑龙江中医药大学附属第一医院针灸五科病房招募的首次脑卒中后肩手综合征病人74例作为研究对象,采用随机数字表法分为龙虎交战针刺组和常规针刺组,每组37例。两组病人均给予基础治疗,常规针刺组在基础治疗基础上给予常规针刺治疗,龙虎交战针刺组在基础治疗及常规针刺基础上给予龙虎交战针刺治疗。比较两组病人治疗前、治疗4周后血清CGRP、BK水平及视觉模拟量表(VAS)评分、肩手综合征评估量表(SHSS)评分、上肢Fugl-Meyer评定量表(FMA)评分,并评定两组的临床疗效。结果:治疗4周后,两组血清BK水平、VAS评分、SHSS评分均较治疗前降低(P<0.05),FMA评分、血清CGRP水平较治疗前升高(P<0.05);且龙虎交战针刺组血清BK水平、VAS评分、SHSS评分低于常规针刺组(P<0.05),FMA评分、血清CGRP水平高于常规针刺组(P<0.05)。龙虎交战针刺组临床总有效率为94.12%,高于常规针刺组的...     

定痛汤对无先兆性偏头痛病人血CGRP、SP的影响及临床疗效分析

目的观察定痛汤对无先兆性偏头痛病人血中降钙素基因相关肽(CGRP)和P物质(SP)的影响及临床疗效。方法将60例无先兆性偏头痛病人随机分成两组,治疗组30例给予定痛汤治疗,对照组30例给予盐酸氟桂利嗪胶囊治疗。两组疗程均为15d。采用酶联免疫吸附测定(Elisa)检测病人血中CGRP和SP含量。结果治疗组总有效率90.0%,对照组总有效率65.6%,两组总有效率比较差异有统计学意义(P0.05)。两组血中CGRP和SP含量的差异有统计学意义(P0.01),CGRP和SP含量均有不同程度的降低,但治疗组血中CGRP和SP含量下降的程度较对照组更加明显(P0.05)。结论定痛汤可以明显提高无先兆偏头痛的临床疗效,且可以降低偏头痛病人血中CGRP和SP含量。     

腕踝针配合耳穴贴压对老年胃肠癌患者术后疼痛和肠胃功能的影响

目的 观察腕踝针配合耳穴贴压对老年胃肠癌患者术后恢复的影响。方法 选取2021年6月—2023年6月于江苏省中医院拟进行手术的老年胃肠癌患者70例，按照数字表法随机分为观察组(n=35)及对照组(n=35)。术后，对照组给予耳穴贴压治疗，观察组行腕踝针联合耳穴贴压治疗，2组均连续治疗7 d。观察并比较2组患者治疗效果、疼痛程度[术前(T0)、术后24 h(T1)、术后48 h(T2)及术后72 h(T3)采用疼痛视觉模拟量表(VAS)进行评分]、疼痛介质[血清β-内啡肽(β-ep)、 P物质(SP)和5-羟色胺(5-HT)]水平变化、胃癌及肠癌患者肠胃功能恢复时间及不良反应发生情况。结果 治疗后，观察组治疗总有效率高于对照组(94.29%vs 80.00%,P<0.05);与T0相比，2组T1～T3的VAS评分均明显降低(P<0.05),且在T2和T3时，观察组VAS评分低于对照组(P<0.05)。治疗前，2组血清SP、 β-ep及5-HT水平差异均无统计学意义(P>0.05);与同组治疗前比较，治疗后2组血清SP水平均降低(P<0.05),且治疗后观察组...     

针刺联合芍药甘草汤治疗偏头痛的临床疗效研究

目的探讨针刺联合芍药甘草汤治疗偏头痛的临床疗效。方法选取2010年6月—2014年6月城固县中医医院精神卫生分院收治的偏头疼患者72例,随机分为对照组和观察组,各36例。对照组患者给予盐酸氟桂利嗪治疗,观察组患者给予针刺联合芍药甘草汤治疗。比较两组患者治疗前及治疗30 d后口述疼痛分级(VRS)评分、视觉模拟量表(VAS)评分、生活质量评价量表(SF-36)评分。结果治疗前两组患者VRS评分、VAS评分及SF-36各维度评分比较,差异无统计学意义(P0.05);治疗后观察组患者VRS评分、VAS评分低于对照组,SF-36各维度评分高于对照组(P0.05)。治疗后两组患者VRS评分、VAS评分均低于治疗前,SF-36各维度评分均高于治疗前(P0.05)。结论针刺联合芍药甘草汤可有效改善偏头痛患者临床症状,提高患者生活质量。     

针刺与康复运动治疗重型颅脑损伤意识障碍的交互作用研究

目的观察并分析早期针刺与康复运动双因素治疗重型颅脑损伤患者意识障碍的交互作用和临床意义。方法 120例重型颅脑损伤后急性期昏迷患者在常规治疗基础上随机分为综合组、针刺组、康复组和对照组。综合组予针刺和康复运动治疗;针刺组予针刺治疗;康复组行康复运动;对照组不针刺、不做康复运动。在治疗前后均对其进行Glasgow昏迷量表(GCS)评定。结果治疗1个月后,4组GCS评分均有明显提高。综合组促醒时间优于对照组(P<0.05);3个治疗组GCS评分明显优于对照组(P<0.01);综合组、针刺组促醒时间明显优于康复组、对照组(P<0.01)。结论重型颅脑损伤昏迷患者早期开展针刺及康复运动能明显缩短其昏迷时间,减轻意识障碍程度,改善预后。针刺腧穴、康复训练对颅脑损伤患者的意识障碍均有促醒作用。针刺促醒作用强,起效快捷,疗效显著,康复运动促醒作用较弱,起效缓慢。     

丹七软胶囊治疗偏头痛的临床研究

目的探讨丹七软胶囊治疗偏头痛病人的临床疗效及对血清基质金属蛋白酶-9(MMP-9)水平的影响。方法选取2015年1月—2017年12月在我科就诊的偏头痛病人52例,随机分成对照组(每晚口服氟桂利嗪5 mg)和治疗组(每晚口服氟桂利嗪5 mg及丹七软胶囊5片,每日3次治疗),每组病人均于治疗前进行视觉模拟评分法(VAS)评分和血清MMP-9检测,治疗2周后再次进行VAS评分和血清MMP-9检测,并对临床疗效进行评估。结果治疗后治疗组临床疗效总有效率为96.15%,明显高于对照组的73.08%(P0.05)。治疗前两组病人VAS评分和血清MMP-9水平差异无统计学意义,治疗后两组VAS评分和血清MMP-9水平较治疗前下降,且治疗组较对照组降低明显(P0.05)。结论丹七软胶囊能显著降低偏头痛病人VAS评分和血清MMP-9水平,对偏头痛有明显治疗效果。     

慢性肺源性心脏病患者血浆CGRP和SP水平变化及临床意义

采用放射免疫分析法测定37例肺心病患者(肺心病组,急性期21例、缓解期16例)及20例正常人(对照组)血浆降钙素基因相关肽(CGRP)和P物质(SP)水平,同时检测动脉血氧分压(PaO2);其中16例缓解期患者测平均肺动脉压(MPAP)及体动脉、体静脉、肺动脉血浆CGRP和SP水平;对血浆CGRP和SP水平与PaO2、MPAP进行相关性分析。结果肺心病组血浆CGRP水平低于对照组(P<0.01),且与PaO2均呈正相关(r=0.658,P<0.01;r=0.597,P<0.01)。肺心病组急性期CGRP及SP水平均低于缓解期(P<0.01);急性期SP水平与PaO2呈正相关(r=0.314,P<0.05);CGRP、SP水平与MPAP均呈明显负相关(r=-0.658,P<0.05;r=-0.661,P<0.05)。证实慢性缺氧时血浆CGRP、SP水平下降,CGRP、SP变化可反映肺心病病情,二者降低可促进肺动脉高压的形成。     

帕瑞昔布钠超前镇痛对妇科手术患者术后镇痛的影响

目的探讨帕瑞昔布钠用于超前镇痛对妇科手术患者术后镇痛的影响。方法将我院2011年10月—2012年2月妇科腹腔镜手术患者56例随机分为观察组和对照组,各28例。观察组于麻醉诱导前30min静脉给予帕瑞昔布钠40mg,对照组给予0.9%氯化钠溶液4ml,两组其他处理相同。采用视觉模拟评分(VAS)对两组术后2、6、12、24h疼痛情况进行评定,并对其满意度进行调查。结果观察组不同时点VAS评分比较,差异均无统计学意义(P>0.05),术后2、6、12h VAS评分明显低于对照组,差异均有统计学意义(P<0.05);术后24h VAS评分与对照组比较,差异无统计学意义(P>0.05);对照组不同时点VAS评分比较,差异均有统计学意义(P<0.05)。经术后回访,观察组满意度高于对照组,差异有统计学意义(P<0.05)。结论帕瑞昔布钠用于妇科超前镇痛,可明显减轻术后疼痛,且不良反应少。     

疏脑解郁汤对脑卒中后抑郁病人血清P物质及神经肽Y的影响

目的 探讨疏脑解郁汤对脑卒中后抑郁(PSD)病人血清P物质(SP)及神经肽Y(NPY)的影响。方法 选取2017年10月—2019年12月于山西省中医院老年病科住院部及门诊就诊的气郁血瘀痰阻PSD病人60例作为研究对象,按照完全随机原则分为治疗组和对照组,每组30例。对照组给予帕罗西汀片,治疗组给予疏脑解郁汤,治疗8周观察疗效。结果 治疗后,两组中医证候总积分均较治疗前降低,且治疗组低于对照组,差异有统计学意义(P<0.05);两组中医证候疗效比较,治疗组总有效率为90.0%,对照组总有效率为63.3%,治疗组优于对照组(P<0.05);治疗后,两组汉密尔顿抑郁量表(HAMD)评分、美国国立卫生研究院卒中量表(NIHSS)评分均较治疗前降低、日常生活活动能力(ADL)评分较治疗前升高(P<0.05)。治疗后,两组血清SP水平较治疗前降低,且治疗组血清SP水平低于对照组(P<0.05);治疗后,两组血清NPY水平较治疗前升高,且治疗组血清NPY水平高于对照组(P<0.05)。相关分析显示,SP与HAMD的相关系数r=0.778,P<0.001,NPY与...     

循经远取动法针刺结合关节腔注射治疗肩周炎的疗效观察

目的 观察循经远取动法针刺结合肩关节注射治疗对肩周炎的临床疗效。方法 选取 2020年1月—2022年10月在九江市第一人民医院疼痛科就诊的肩周炎患者58例，通过随机数字表法分为观察组和对照组，每组29例。对照组采用单纯影像引导下肩关节注射治疗；观察组在肩关节注射基础上加用循经远取动法针刺治疗。治疗前后分别对2组患者视觉模拟量表评分(VAS)、肩关节评分量表Constant Murley(CMS)值对比分析，并评价临床疗效。结果 2组患者治疗后VAS评分[观察组(2.14±1.43)、对照组(2.24±1.35)]较治疗前[观察组(5.28±1.03)、对照组(5.48±1.12)]均降低(P<0.01);CMS评分[观察组(71.52±13.36)、对照组(63.55±16.16)]值较治疗前[观察组(50.21±13.12)、对照组(51.59±12.27)]均提高(P<0.01); 2组治疗前后VAS评分差值相当(P>0.05),但观察组治疗前后CMS评分差值较对照组升高更明显[(21.86±16.1)vs(11.97±7.79),P<0.01];观察组的...     

Holistic acupuncture approach to idiopathic refractory nausea, abdominal pain and bloating

AIM： To evaluate the effectiveness of a holistic acupuncture approach on nausea, pain, bloating and electrogastrogram （EGG） parameters in patients with intractable symptoms.
METHODS： Twelve patients with no or mild nausea （those without nausea had bloating or pain） and 10 with a histool of moderate to severe nausea were referred for acupuncture. All underwent an EGG and were treated at acupuncture points PC6, SP4 and DU20. Visual analog scales （VAS） assessing severity of nausea, pain and bloating were obtained before and after acupuncture treatment. Nineteen patients received three and three patients received two treatments.
RESULTS： VAS scores for nausea reflected the clinical assessment and differed significantly between mild and moderate/severe nausea groups. Acupuncture significantly improved severity of nausea in both groups with improved pre-treatment nausea between the first and third treatments in the moderate/severe nausea group. Pain scores improved with acupuncture in the mild nausea group only and bloating improved only with the first treatment in this group. Patients with bloating with VAS scores greater than 35 pre-treatment improved with acupuncture and over all VAS scores for pain improved with treatment. Acupuncture increased the power in the 2.7 to 3.5 cpm range in the EGG.
CONCLUSION： In this uncontrolled clinical study, a holistic acupuncture approach significantly improved nausea in patients with refractory symptoms and increased the power in the 2,7-3,5 cpm component of the electrogastrogram, Bloating and pain VAS scores improved acutely with treatment, This study suggests that acupuncture may be effective in this refractory group of patients and further study using appropriate controls is warranted,     

高频重复经颅磁刺激规律间歇治疗丘脑梗死后中枢性疼痛的临床研究

目的探究高频重复经颅磁刺激（hrTMS）规律间歇治疗丘脑梗死后中枢性疼痛的临床疗效和作用机制。 方法选取安庆市立医院神经内科自2020年4月至2021年12月收治的64例丘脑梗死后中枢性疼痛患者,采用单盲-随机数字表法分为hrTMS组和对照组,每组32例。2组患者治疗期间口服布洛芬缓释胶囊0.4 g,bid。hrTMS组行hrTMS治疗,对照组行无磁场脉冲发射的伪线圈治疗。比较2组患者的视觉模拟量表（VAS）评分、运动诱发电位（MEP）潜伏期变化及治疗总有效率。 结果hrTMS组患者治疗前和治疗2、4、8周后的VAS评分逐渐下降,差异有统计学意义（P<0.05）。对照组治疗前和治疗2、4周后的VAS评分比较,差异有统计学意义（P<0.05）,但治疗后4、8周的VAS评分比较,差异无统计学意义（P>0.05）。2组患者治疗前和治疗2周后VAS评分比较,差异均无统计学意义（P>0.05）;治疗4、8周后的VAS评分比较,差异均有统计学意义（P<0.05）。治疗8周后,hrTMS组患者的MEP潜伏期较治疗前明显缩短,且较对照组MEP潜伏期明显缩短,差异具有统计学意义（P<0.05）。hrTMS组患者治疗8周后的总有效率（71.88%）明显高于对照组（15.63%）,差异具有统计学意义（P<0.05）。 结论hrTMS规律间歇治疗可缓解丘脑梗死后中枢性疼痛患者的疼痛程度且疗效持续显著,可能作用机制与提高脑梗死患者大脑皮质兴奋性有关。     

Interleukin-1 beta up-regulates tissue inhibitor of matrix metalloproteinase-1 mRNA and phosphorylation of c-jun N-terminal kinase and p38 in hepatic stellate cells

AIM: To study the relationship between interleu-kin-1beta (IL-1β) up-regulating tissue inhibitor of matrix metalloproteinase-1 (TIMMP-1) mRNA expression and phosphorylation of both c-jun N-terminal kinase (JNK) and p38 in rat hepatic stellate cells (HSC). METHODS: RT-PCR was performed to measure the expression of TIMMP-1 mRNA in rat HSC. Western blot was performed to measure IL-1β-induced JNK and p38 activities in rat HSC. RESULTS: TIMMP-1 mRNA expression (1.191±0.079) was much higher after treatment with IL-1β(10 ng/mL) for 24 h than in control group (0.545±0.091) (P<0.01). IL-1βactivated JNK and p38 in a time-dependent manner. After stimulation with IL-1βfor 0, 5, 15, 30, 60 and 120 min, the JNK activity was 0.982±0.299, 1.501±0.720, 2.133±0.882, 3.360±0.452, 2.181±0.789, and 1.385±0.368, respectively. There was a significant difference in JNK activity at 15 min (P<0.01), 30 min (P<0.01) and 60 min (P<0.01) in comparison to that at 0 min. The p38 activity was 1.061±0.310, 2.050±0.863, 2.380±0.573, 2.973±0.953, 2.421±0.793, and 1.755±0.433 at the 6 time points (0, 5, 15, 30, 60 and 120 min) respectively. There was a significant difference in p38 activity at 5 min (P<0.05), 15 min (P<0.01), 30 min (P<0.01) and 60 min (P<0.01) compared to that at 0 min. TIMMP-1 mRNA expression trended to decrease in 3 groups pretreated with different concentrations of SP600125 (10μmol/L, 1.022±0.113; 20μmol/L, 0.869±0.070; 40μmol/L, 0.666±0.123). Their decreases were all significant (P<0.05, P<0.01,P<0.01) in comparison to control group (without SP600125 treatment, 1.163±0.107). In the other 3 groups pretreated with different concentrations of SB203580 (10μmol/L, 1.507±0.099; 20μmol/L, 1.698±0.107; 40μmol/L, 1.857±0.054), the expression of TIMMP-1 mRNA increased. Their levels were higher than those in the control group (without SB203580 treatment, 1.027±0.061) with a significant statistical significance CONCLUSION: IL-1βhas a direct action on hepatic fi-brosis by up-regulating TIMMP-1 mRNA expression in rat HSC. JNK and p38 mitogen-activated protein kinases (MAPKs) are involved in IL-1β-induced TIMMP-1 gene expression, and play a distinct role in this process, indicating that p38 and JNK pathways cooperatively mediate TIMP-1 mRNA expression in rat HSC.     

Acupuncture versus metoprolol in migraine prophylaxis: a randomized trial of trigger point inactivation

Abstract. Objectives . To compare the effects of dry needling of myofascial trigger points in the neck region to metoprolol in migraine prophylaxis. Design . Randomized, group comparative study. patients, investigator and statistician were blinded as to treatment, the therapist was blinded as to results. Setting . Outpatient pain clinic in the northern Copenhagen area. Patients were referred by general practitioners or respondents to newspaper advertisements. Subjects . Included were patients with a history of migraine with or without aura for at least 2 years. Excluded were persons with contraindications against treatment with beta blockers, chronic pain syndromes, pregnancy or previous experience with acupuncture or beta-blocking agents. A total of 85 patients were included; 77 completed the study. Interventions . After a 4-week run-in period, patients were allocated to a 17-week regimen either with acupuncture and placebo tablets or to placebo stimulation and metoprolol 100 mg daily. Results . Both groups exhibited significant reduction in attack frequency (P < 0.01). No difference was found between the groups regarding frequency (P > 0.20) or duration (P > 0.10) of attacks, whereas we found a significant difference in global rating of attacks in favour of metoprolol (P < 0.05). Conclusions . Trigger point inactivation by dry needling is a valuable supplement to the list of migraine prophylactic tools, being equipotent to metoprolol in the influence on frequency and duration (but not severity) of attacks, and superior in terms of negative side-effects.     

偏头痛病人血浆内皮素及降钙素基因相关肽测定的临床意义

目的测定偏头痛病人血浆内皮素(ET)和降钙素基因相关肽(CGRP)含量,探讨其在偏头痛发生与发展中的意义.方法选择34例诊断明确的偏头痛病人,按发病时间分为发作期和间歇期,抽取肘静脉血2 mL,采用放免分析技术(RIA)分别测定ET及CGRP含量,并与31名同期健康人作对照.结果偏头痛组ET及CGRP含量显著高于正常对照组(P<0.01);重度发作组与轻中度组及间歇期组相比,ET的水平前者高于后两者(P<0.05或P<0.01);CGRP轻中度组及间歇期组与正常对照组相比,有统计学意义(P<0.01或P<0.05),ET轻中度组有统计学意义(P<0.05).对照组(r=0.5860,P<0.01)和间歇期组(r=0.6047,P<0.05)ET和CGRP含量变化呈正相关.结论偏头痛病人血浆ET及CGRP水平的变化可能参与了偏头痛的发病过程.     

复方多黏菌素B软膏联合中药坐浴对老年肛周脓肿术后病人伤口愈合效果及血清表皮生长因子表达的影响

目的探讨复方多黏菌素B软膏联合中药坐浴对老年肛周脓肿术后病人伤口愈合效果及血清表皮生长因子(EGF)表达的影响。方法选取我院肛肠外科78例老年肛周脓肿拟行手术治疗的病人,采用单盲随机数表法将其分为试验组(40例)和对照组(38例)。2组病人术后第1天开始均采用医院自制中药包坐浴,15~20 min/次,2次/d。试验组病人于坐浴后擦干患处,涂抹复方多黏菌素B软膏。治疗7 d后,观察2组伤口愈合情况,采用VAS、生活质量量表(SF-36)、匹兹堡睡眠质量指数(PSQI)量表评价2组病人的生活质量,采用ELISA法检测2组病人的血清EGF水平。结果治疗7 d后,试验组的伤口痊愈者较对照组显著增多(P<0.05),伤口水肿者较对照组显著减少(P<0.05);2组肛瘘和伤口渗血发生率差异无统计学意义(P>0.05);试验组的VAS、PSQI评分较治疗前和对照组显著下降(P<0.01),SF-36评分及EGF水平较治疗前和对照组显著升高(P<0.01)。试验组和对照组病人在第10天伤口愈合的比例分别为40%和26%,2组比较,差异有统计学意义(P<0.05)。结论复方多黏菌素B软膏联合中药坐浴对老年肛周脓肿术后病人的伤口愈合具有较好的临床疗效,其起效快,可以缓解疼痛、改善生活质量和睡眠状况,并且通过上调病人的血清EGF水平促进伤口愈合。     

Effect of Residual Interatrial Shunt on Migraine Burden After Transcatheter Closure of Patent Foramen Ovale

ObjectivesThis study sought to evaluate the long-term effect of transcatheter patent foramen ovale (PFO) closure on migraineurs with and without aura and examine the effect of residual right-to-left shunt.BackgroundMany studies reported improvement in migraine symptoms after PFO closure, yet randomized trials failed to reach its clinical endpoints.MethodsThe study retrospectively analyzed data from 474 patients who underwent transcatheter PFO closure at Massachusetts General Hospital. Patients completed a migraine burden questionnaire at baseline and at follow-up. Migraine severity is reported as migraine frequency (days/month), average duration (min), and migraine burden (days × min/month). Improvement following closure was defined as complete abolishment of symptoms or >50% reduction in migraine burden.ResultsA total of 110 migraineurs who underwent PFO closure were included; 77.0% had aura and 23.0% were without aura, and 91.0% had a cryptogenic stroke. During long-term median follow-up of 3.2 (interquartile range: 2.1 to 4.9) years, there was a significant improvement in migraine symptoms in migraineurs with or without aura. Migraine burden was reduced by >50% in 87.0% of patients, and symptoms were completely abolished in 48%. Presence of aura was associated with abolishment of migraine (odds ratio: 4.30; 95% confidence interval: 1.50 to 12.30; p = 0.006). At 6 months after PFO closure, residual right-to-left shunt was present in 26% of patients. Absence of right-to-left shunt was associated with improvement in migraine burden by >50% (odds ratio: 4.60; 95% confidence interval: 1.30 to 16.10; p = 0.017).ConclusionsLong-term follow-up after transcatheter PFO closure was associated with significant improvement in migraine burden. Aura was a predictor of abolishing symptoms. Absence of residual right-to-left shunt was a predictor of significant reduction in migraine burden.     

A型肉毒毒素治疗偏头痛大鼠的作用机制

目的研究A型肉毒毒素（BTX-A）治疗偏头痛的机理。方法建立偏头痛大鼠模型,分别应用BTX-A皮下注射（BTX-A组）及生理盐水注射（生理盐水组）治疗,并设立健康对照（对照组）。采用放射免疫法测定各组降钙素基因相关肽（CGRP）和P物质（SP）含量。结果生理盐水组CGRP、SP含量高于对照组（P均〈0.05）,BTX-A组低于生理盐水组（P均〈0.05）。结论 BTX-A抑制三叉神经感觉通路CGRP及SP释放可能是其治疗偏头痛大鼠的机制之一。     

整脊推拿手法联合针刺治疗腰椎间盘突出症的疗效观察

目的 观察整脊推拿手法联合针刺治疗腰椎间盘突出症(LDH)的疗效。方法 选择中山市中医院2018年5月至2021年3月收治的LDH患者90例,采用随机数字表法将其分为观察组和对照组,每组45例。对照组采用整脊推拿手法治疗,观察组采用整脊推拿手法联合针刺治疗,两组疗程均为4周。比较两组临床疗效,治疗前后日本骨科协会(JOA)评分、视觉模拟量表(VAS)评分、生活质量评分,以及腰椎伸直过程、屈曲过程的平均表面肌电值(AEMG)。结果 观察组临床总有效率高于对照组,差异有统计学意义(95.56%vs80.00%;χ²=5.075,P=0.024)。治疗后,两组JOA、SF-36评分均升高,VAS评分降低,与同组治疗前比较差异有统计学意义(P <0.05),且观察组变化较对照组更显著(P <0.05)。治疗后两组腰椎伸直过程的AEMG均升高,屈曲过程的AEMG均降低,与同组治疗前比较差异有统计学意义(P <0.05),且观察组变化较对照组更显著(P <0.05)。结论 整脊推拿手法联合针刺治疗LDH可促进疼痛缓解,改善腰背肌力学效应和腰椎功能,提高...     

加强扬刺百会穴对抑郁症患者体内单胺类神经递质代谢影响的研究

目的探讨加强扬刺百会穴治疗抑郁症患者的疗效,及其对患者体内单胺类神经递质代谢影响的作用机制。方法选取符合纳入标准的抑郁症患者40例,其汉密尔顿焦虑量表(HAMI)评分均大于20分,采用加强扬刺法针刺百会穴治疗。于治疗前后分别检测患者血浆中单胺类递质5-羟色胺(5-HT)及去甲肾上腺素(NE)的含量变化,并与40名健康志愿者进行对比。结果治疗前后40名抑郁症患者体内5-HT及NE的含量均有统计学意义(P<0.05)。治疗前二者的含量显著低于健康志愿者(P<0.05);治疗后与健康志愿者无统计学意义(P>0.05)。结论加强扬刺百会穴可缓解抑郁症患者的各种症状,调节患者血浆中单胺类神经递质的代谢水平。