胆囊息肉样病变的临床病理诊断分析

目的:探究胆囊息肉样病变的临床病理诊断价值.方法:本次研究资料选取时间段为2019年1月至2021年1月,患者为我院诊治的58例胆囊息肉样病变患者,回顾性分析上述患者的临床诊断资料.结果:58例患者中右上腹疼痛38例(65.52％).非肿瘤性息肉病变患者占比高于肿瘤性息肉病变患者(P<0.05),其中最多的为胆固醇性息...     

胆囊息肉样病变的超声诊断

对我院 1999年 1月～ 2 0 0 3年 1月超声诊断 ,并经手术病理证实的 6 2例胆囊息肉样病变进行分析 ,以探讨其诊断价值。1　资料与方法6 2例胆囊息肉样病变均为我院住院患者 ,其中男性 4 2例 ,女性 2 0例 ,平均年龄 4 6岁。病程最长11年 ,最短 6个月。临床表现主要为不同程度的右上腹间歇性隐痛、腹胀或不适者 5 6例 ;无症状者 6例 ,仅在体检时发现。全部病例均由超声诊断 ,并经手术、病理检查证实。所用仪器为SSH - 14 0A ,LOGIQ2 0 0型超声诊断仪 ,探头频率为 3 5Hz ,检查前空腹 8- 12小时 ,患者取仰卧位或左侧卧位 ,必要时采取坐位探测…     

56例胆囊息肉样病变的声像图与病理诊断分析

2000年6月～2003年6月，我们对56例胆囊息肉样病变患者行手术治疗。现将术后病理诊断与手术前声像图改变进行对照分析．以期为本病的早期诊断提供可靠依据。     

胆囊息肉样病变的癌变危险因素分析

目的探讨胆囊息肉样病变（PLG）的癌变危险因素。方法选择118例行手术治疗且经病理证实的PLG患者,对其临床特征、腹部超声表现及病理类型进行统计分析。结果118例PLG患者中,男女比例为1：2．03,平均年龄46．2岁,临床多无特异性症状;腹部超声诊断PLG的灵敏度为80．5％。PLG以非肿瘤性息肉为主,其中胆固醇性息肉占72．9％;肿瘤性息肉占9．3％,其中癌变1例（癌变率为0．8％）;118例PLG患者的平均息肉直径为7．86rain,息肉直径≥7mm者肿瘤性息肉占90．9％、非肿瘤性息肉占54．2％（P〈0．05）。肿瘤性息肉中单发者占63．6％,非肿瘤性息肉者占24．3％（P〈0．05）。结论PLG以胆固醇性息肉为主;年龄≥50岁、息肉直径≥7mm、单发或腹部超声表现为中低或等回声的PLG癌变可能性较大,应密切随访,观察息肉变化情况,必要时行外科手术治疗。     

中老年胆囊息肉样病变术后病理与术前B超诊断的对照分析

中老年胆囊息肉样病变术后病理与术前Ｂ超诊断的对照分析穆庆霞胡淑芳胡建群张峰南京医科大学第一附属医院（２１００２９）胆囊息肉样病变（简称胆囊息肉）是胆囊粘膜局限性隆起病变的统称。随着超声技术的发展，超声仪器的不断改进，本病的检出率达１００％。现将我院近...     

大肠息肉与胆囊息肉样病变的相关性

目的:探讨大肠息肉与胆囊息肉样病变(polypoid lesions of the gallbladder,PLG)的相关性.方法:随机选取我院行结肠镜检查的患者211例,分为大肠息肉组(n=111)和对照组(n=100),利用超声检查对大肠息肉组PLG的发生情况进行观察,并与对照组进行对比分析.结果:大肠息肉组PLG的发生率明显高于对照组(x2=13.60,P<0.001);男女性大肠息肉组间PLG的发生率无差异:按大肠息肉的病理类型进行分层比较显示非腺瘤性大肠息肉组PLG的发生率高于对照组(x2=3.86,P<0.05),而腺瘤性大肠息肉组PLG的发生率明显高于对照组(x2=19.04,P<0.001),且高于非腺瘤性大肠息肉组(x2=3.94,P<0.05).结论:大肠息肉与PLG之间可能存在一定的相关性.     

胆囊息肉样病变经手术病理证实22例报告

我院收治胆囊息肉样病变22例,均经手术切除和病理证实,现将临床资料报告并讨论如下。临床资料临床表现:病程短者1月,长者19年。主要症状为慢性右上腹部隐痛或钝痛(18例),部分病例伴有右肩背部放射痛(4例)。有4例无症状,为健康体检发现。除2例有右上腹深在触痛外,余20例无腹部阳性体征。B型超声检查:22例检查均提示胆囊壁有直径0.1～1.0cm大小、中等强度回声光     

胆囊息肉样病变103例临床及病理分析

目的　探讨胆囊息肉样病变 (PLG)的临床表现、影像学、病理学特点。方法　对 10 3例PLG患者的临床、影像学、病理学及术后随访资料作统计分析。结果　胆固醇性息肉 5 4例 ,炎性息肉 34例 ,未见息肉 7例 ,胆囊肿瘤性息肉 (NPG) 8例 (腺瘤 6例、腺癌 2例 )。在直径≤ 5mm、6～ 10mm、11～ 15mm、>15mm组 ,NPG分别为 0(0 / 2 2 )、3例 (3/ 6 4 )、4例 (4 / 16 )、1例 (1/ 1) ,腺癌 2例直径均≥ 15mm ,NPG在直径 >10mm组多于≤ 10mm组。NPG中单发 6例 (6 / 8) ,非NPG中单发 2 7例 (2 7/ 95 )。术后中长期并发症发生率 32 8% (19/ 5 8)。结论　PLG应先做定期B超随访 ,出现下述表现之一者宜切除胆囊 :直径 >10mm、单发广基、随访中增大、伴有胆囊结石、症状明显或其它影像学检查提示NPG。     

胆囊息肉样病变31例临床分析

作者报告了31例胆囊息肉样病变,用B超确诊的术前诊断率达83.87%(26/31),并对其发病率、临床表现及诊治进行了分析。     

胆囊息肉样病变203例临床分析

目的　探讨胆囊息肉样病变 (PLG )的临床若干问题 ,提高其诊疗水平。方法　腹部B超检出胆囊息肉样病变患者 2 0 3例 ,其中 3 0例经腹腔镜或剖腹胆囊摘除术 ,对其临床表现与病理特点进行比较。结果　 3 0例患者中男性 12例 ,女性 18例 ,年龄 2 8～ 62岁 ,平均年龄 3 8岁。有症状者 16例 ,占 5 3 .3 3 %。真性肿瘤 5例 ( 16.66% ) ,息肉样病变 2 5例 ( 83 .3 3 % ) ,胆囊增厚 18例( 60 .0 % ) ,合并结石者 4例 ( 13 .3 % )。结论　胆囊息肉样病变属胆囊良性肿瘤 ,但少数有恶变危险 ,建议对单发性胆囊息肉样病变直径≥ 10mm或多发性的直径≥ 12mm、直径 <10mm ,但胆囊壁显著增厚 ( >4mm)及 (或 )伴有结石、有较明显的临床症状和B超动态检查息肉短期增大者应手术治疗。     

Prevalence and risk factors of gallbladder polypoid lesions in Chinese petrochemical employees

AIM:To investigate the prevalence and risk factors of polypoid lesions of the gallbladder (PLGs) in petrochemical employees in Ningbo, Zhejiang Province, China. METHODS:All active and retired employees aged 20-90 years (n = 11098) of a refinery and chemical plant in eastern China were requested to participate in a health survey. The participants were subjected to interview, physical examination, laboratory assessments and ultrasonography. All the participants were invitedto have a physical examination after a face-to-face interview. Fasting blood samples were obtained from the antecubital vein, and the samples were used for the analysis of biochemical values. Abdominal ultrasonography was conducted. RESULTS:A total of 10461 (7331 men and 3130 women) current and former petrochemical employees attended for screening. The overall prevalence of postcholecystectomy, gallstones and PLGs was 0.9%, 5.2% and 7.4%, respectively. Compared with the increased prevalence of either gallstones or post-cholecystectomy in older persons, PLGs were more common in the middle-aged, peaking in those aged 40-59 years. Excluding the patients with gallstones, gallstones mixed with PLGs, or those who had undergone cholecystectomy, in the remaining 9828 participants, the prevalence of PLGs in men (8.9%) was significantly higher than that in women (5.5%, P < 0.001). The analyzed risk factors with increased OR for the development of PLGs were male gender (OR = 1.799, P < 0.001), age ≥ 30 years (OR = 2.699, P < 0.001) and hepatitis B surface antigen (HBsAg) positivity (OR = 1.374, P = 0.006). CONCLUSION:PLGs are not rare among Chinese petrochemical employees. Male gender, HBsAg positivity, and middle age are risk factors for developing PLGs.     

Analysis of risk factors for polypoid lesions of gallbladder among health examinees

AIM: To investigate the prevalence and risk factors of polypoid lesions of gallbladder (PLG) among the health examinees in the Shanghai region, China.METHODS: A total of 11 816 subjects who underwent health examinations in our hospital between August 2010 and February 2011 were analyzed retrospectively. Among them, there were 7174 men and 4642 women. PLG was diagnosed by the real-time ultrasonography. Those with the body mass index (BMI) ≥ 28 were considered to be obese. Blood biochemical indices were detected with the fully automatic biochemical analyzer and hepatitis B surface antigen (HBsAg) was tested by the automated enzyme immunoassay. The correlations between the prevalence of PLG and age, sex, BMI, serum cholesterol (T-Cho), triglycerides (TG), blood sugar, HBsAg, high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C), gallstone and fatty liver were investigated. After univariate analysis of 11 variables, stepwise logistic regression analysis was performed to explore the risk factors of PLG.RESULTS: There was a significant difference in sex, T-Cho, HBsAg, HDL-C, LDL-C and fatty liver between the PLG-positive group and the PLG-negative group (332/163 vs 6842/4479, P = 0.003; 22/473 vs 295/11 026, P =0.013; 92/403 vs 993/10 328, P = 0.001; 47/448 vs 332/10 989, P = 0.001; 32/463 vs 381/10 940, P = 0.001; 83/412 vs 3260/8061, P = 0.001). No significant difference was found in the age, BMI, TG, blood sugar and gallstone between the two groups (47.3 ± 26 vs 45.1 ± 33, P = 0.173; 59/436 vs 1097/10 224, P = 0.102; 52/443 vs 982/10 339, P = 0.158; 17/478 vs 295/11 026, P = 0.26; 24/471 vs 395/10 926, P = 0.109). Logistic regression analysis showed that the sex, HBsAg and HDL-C were independent risk factors for the development of PLG in a descending order of HDL-C > HBsAg > sex.CONCLUSION: In healthy people, the male gender, positive HBsAg, and low HDL-C confer higher risks of PLG development.     

胆囊息肉样病变的临床流行病学特点及其易感性因素

目的:探讨青岛地区胆囊息肉样病变(polypoid lesion of gallbladder,PLG)的临床流行病学特点及其易感性因素.方法:选择2009/01-2009/12在本院健康体检中心体检的27400人作为调查对象,采用分层随机整群抽样法,对1678例超声诊断PLG患者进行临床流行病学调查,并抽取1700人非PLG者作为对照组.采用多因素非条件Logistic回归分析生活方式、行为因素、空腹血糖(FPG)、三酰甘油(TG)、胆固醇(CHO)和体质量指数(BMI)、脂肪肝、胆囊炎、胆囊结石和胆囊癌等,以OR值为PLG易感性因素.分析PLG直径>10mm行胆囊切除术219例患者的超声病理学特点以及手术治疗良性非肿瘤性PLG合理性.结果:27400人健康体检中,资料完整27301人,应答率为99.64%.经超声诊断PLG者1678例,发病率6.15%,其中男性59.95%(1006/1678),女性40.05%(672/1678),男女比例1.5∶1;30-59岁占64.96%(1090/1678).P L G单发37.72%(633/1678),多发62.28%(1045/1678);直径≤10mm占...     

Pre-operative factors that can predict neoplastic polypoid lesions of the gallbladder

AIM:To investigate the preoperative factors that can predict neoplastic polypoid lesions of the gallbladder(PLGs) as well as malignant PLGs.METHODS:A retrospective analysis was conducted on the 210 consecutively enrolled patients who underwent cholecystectomy due to a PLG larger than 10 mm,as was determined by preoperative trans-abdominal ultrasonography or endoscopic ultrasonography.We ana-lyzed the medical,laboratory,radiologic data and the pathologic results.RESULTS:In 210 cases,146 had non-neoplastic po...     

Treatment and surveillance of polypoid lesions of the gallbladder in the United Kingdom

Objectives

The increase in the routine use of abdominal imaging has led to a parallel surge in the identification of polypoid lesions in the gallbladder. True gallbladder polyps (GBP) have malignant potential and surgery can prevent or treat early gallbladder cancer. In an era of constraint on health care resources, it is important to ensure that surgery is offered only to patients who have appropriate indications. The aim of this study was to assess treatment and surveillance policies for GBP among hepatobiliary and upper gastrointestinal tract surgeons in the UK in the light of published evidence.

Methods

A questionnaire on the management of GBP was devised and sent to consultant surgeon members of the Association of Upper Gastrointestinal Surgeons (AUGIS) of Great Britain and Ireland with the approval of the AUGIS Committee. It included eight questions on indications for laparoscopic cholecystectomy and surveillance based on GBP (size, number, growth rate) and patient (age, comorbidities, ethnicity) characteristics.

Results

A total of 79 completed questionnaires were returned. The vast majority of surgeons (>75%) stated that they would perform surgery when a single GBP reached 10 mm in size. However, there was a lack of uniformity in the management of multiple polyps and polyp growth rate, with different surveillance protocols for patients treated conservatively.

Conclusions

Gallbladder polyps are a relatively common finding on abdominal ultrasound scans. The survey showed considerable heterogeneity among surgeons regarding treatment and surveillance protocols. Although no randomized controlled trials exist, national guidelines would facilitate standardization, the formulation of an appropriate algorithm and appropriate use of resources.     

孤立性肺部占位病变的性质与危险因素分析

目的研究孤立性肺部占位病变的性质及恶性危险因素,并探讨其诊疗策略。方法回顾性分析2006年1月～2010年6月于我院住院治疗并获得明确病理结果的孤立性肺部占位性病变的75例患者的临床资料,对年龄、性别、吸烟史、病变部位、病变直径、CT影像学表现等因素与孤立性肺部占位性病变良恶性的关系进行单因素及多因素Logistic回归分析。结果75例孤立性肺部占位性病变患者中,恶性病变53例,良性病变22例。恶性病变中以腺癌和鳞癌最为多见,良性病变中以结核和炎性假瘤最为多见。单因素及多因素Logistic回归分析显示,年龄、病变部位与孤立性肺部病变的良恶性显著相关。结论孤立性肺部占位性病变中恶性比率较高,年龄和病变部位可以作为评价孤立性肺部病变恶变的危险因素。     

Fatty liver is an independent risk factor for gallbladder polyps

BACKGROUNDGallbladder polyps (GBPs) are known to be associated with obesity and metabolic diseases. However, to date, the relationship between GBPs and abnormal body fat distribution, such as fatty liver, visceral obesity, or sarcopenia, has not yet been established.AIMTo evaluate whether GBPs are associated with fatty liver, visceral obesity, or sarcopenia.METHODSWe retrospectively reviewed the medical records of subjects who underwent various laboratory tests, body composition measurement with a non-invasive body composition analyzer, and abdominal ultrasonography during health checkups. A total of 1405 subjects with GBPs were compared with 2810 age- and sex-matched controls.RESULTSThe mean age of the subjects was 46.8 ± 11.7 years, and 63.8% were male. According to multiple logistic regression analysis, the presence of fatty liver [odds ratio (OR) 1.413; 95% confidence interval (CI) 1.218-1.638; P < 0.001] was an independent risk factor for GBP, together with low levels of alanine aminotransferase (OR 0.993; 95%CI 0.989-0.996; P < 0.001). Additionally, fatty liver showed both independent (OR 1.629; 95%CI, 1.335-1.988; P < 0.001) and dose-dependent (moderate to severe fatty liver; OR 2.137; 95%CI, 1.662-2.749; P < 0.001) relationship with large GBPs (≥ 5 mm). The presence of sarcopenia and high visceral fat area were not significantly associated with GBPs.CONCLUSIONFatty liver was found to be closely associated with GBPs irrespective of sarcopenia and visceral obesity.