Comparison of ACL fixation devices using cadaveric grafts

We evaluated two newer forms of femoral fixation of hamstring grafts for anterior cruciate ligament reconstruction, the Endobutton direct (Smith and Nephew, Andover, MA) and Femoral intrafix (Depuy Mitek, Raynham, MA), and compare them to devices that have been evaluated in the literature, the AXL Crosspin (Biomet, Warsaw, IN) and Biotransfix II (Arthrex, Naples, FL). Paired hamstring tendon allografts were fixed in the femoral tunnel of 24 cadaveric bovine knees (6 per group) according to each device's specifications. The free ends (tibial sides) were fixed to the materials testing machine via custom-made cryo-clamps. In Phase I, single load to failure and stiffness were evaluated, and in Phase II, peak displacement was evaluated while cyclic loading was performed over 1000 cycles. One-way analyses of variance were performed to test for differences between groups. There were no significant differences in failure load (p = 0.42) or stiffness (p = 0.39) between the fixation devices. There was also no significant difference in peak displacement measured during the cyclic loading phase (p = 0.32). Our findings suggest that the newer generation devices, Endobutton direct and Femoral intrafix, have similar strength in single load to failure and similar peak displacement during cyclic loading as compared with clinically proven Crosspin techniques. These newer devices, which are designed to accommodate for more anatomic femoral tunnel placement, may provide a reasonable alternative without compromising biomechanical properties.     

Cyclic loading of rotator cuff repairs: A comparison of bioabsorbable tacks with metal suture anchors and transosseous sutures

Purpose: The purposes of the study were (1) to compare rotator cuff repair strengths after cyclic loading of 2 bioabsorbable nonsuture-based tack-type anchors, transosseous sutures, and a metal suture-based anchor, and (2) to correlate bone mineral density with mode of failure and cycles to failure. We hypothesized that specimens with a lower bone density would fail through bone at a lower number of cycles independent of the method of cuff fixation. Type of Study: Ex vivo biomechanical study. Methods: Standardized full-thickness rotator cuff defects were created in 30 fresh-frozen cadaveric shoulders that were randomized to 1 of 4 repair groups: transosseous sutures; Mitek Super suture anchors (Mitek Surgical Products, Westwood, MA); smooth bioabsorbable 8-mm Suretacs (Acufex, Smith & Nephew Endoscopy, Mansfield, MA); or spiked bioabsorbable 8-mm Suretacs (Acufex). All repairs were cyclically loaded from 10 to 180 N; the numbers of cycles to 50% (gap, 5 mm) and 100% (gap, 10 mm) failure were recorded. Results: In comparing the repair groups, we found only 1 significant difference: the number of cycles to 100% failure was significantly higher (P <.05) for the smooth bioabsorbable tack than for the transosseous suture group. There were no statistically significant (P ≤.05) differences in bone mineral densities with regard to each specimen’s mode of failure. Conclusions: Our results suggested that immediate postoperative fixation provided by bioabsorbable tacks was similar to that provided by Mitek anchors and more stable than that provided by transosseous sutures. Therefore, the immediate postoperative biomechanical strength of bioabsorbable tacks seems comparatively adequate for fixation of selected small rotator cuff tears. However, additional evaluation in an animal model to examine degradation characteristics and sustained strength of repair is recommended before clinical use.Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 17, No 4 (April), 2001: pp 360–364     

Failure strengths of concentric and eccentric implants for hamstring graft fixation

The purpose of this study is to compare the initial failure strengths of various interference screw devices used for tibial fixation of hamstring grafts in anterior cruciate ligament reconstruction and the effect of concentric or eccentric screw position. Quadrupled tendon grafts were harvested from freshly killed sheep. The grafts were then prepared and fixed in the distal femur using various devices (Intrafix (DePuy Mitek Raynham, MA, USA), RCI screw (Smith and Nephew Acufex, Mansfield, MA, USA), Wedge screw (Stryker Endoscopy, San Jose, CA, USA) in concentric position and Wedge screw in eccentric position with an interlock pin). The load required to cause mechanical failure of each construct was measured. The Intrafix device had a significantly greater mean strength to failure than all the other implants (mean 941 +/- 280 N) (P = 0.015 to P < 0.0001). The wedge screw inserted concentrically (737 +/- 134 N) had significantly greater initial failure strength than the wedge eccentric with interlock pin (458 +/- 266 N) (P = 0.03) and the RCI screw (464 +/- 107 N) (P = 0.00036). In this sheep model the Intrafix device with sheath inserted concentrically had significantly greater initial failure strength than the other interference screws. Concentric positioning of the wedge interference screw gave significantly greater initial failure strength of a quadruple tendon graft than eccentric positioning. The use of the Intrafix device or concentric positioning of an interference screw should result in increased initial fixation strength of hamstring grafts. This may allow more vigorous early rehabilitation and may result in less late graft laxity after anterior cruciate ligament reconstruction.     

Spontaneous Locking of the Knee After Anterior Cruciate Ligament Reconstruction as a Result of a Broken Tibial Fixation Device

The Intrafix device (DePuy Mitek, Raynham, MA) is one of a number of recently developed products whose aim is to improve fixation of quadrupled hamstring grafts when used for anterior cruciate ligament reconstruction. We present a case of failure and intra-articular migration of the sleeve of an Intrafix device causing locking of the knee 10 weeks after anterior cruciate ligament reconstruction. We were unable to identify the cause of the failure or migration of the device. Rehabilitation had been progressing normally and without incident. The broken fragments were removed arthroscopically, and the reconstruction was found to be intact and healing well. Presumably, the device retained enough mechanical function to allow healing to progress, despite failure of the sleeve. This is, to our knowledge, the first reported case of such an event occurring with the new generation of hamstring graft fixation devices.     

Primary stability of bone-patellar tendon-bone graft fixation with biodegradable pins

Purpose: We evaluated the initial bone-patellar tendon-bone (BPTB) graft fixation strength of biodegradable pins compared with interference screws in anterior cruciate ligament reconstruction using bovine knees. Type of Study: Biomechanical in vitro study. Methods: Ten BPTB grafts from human donors fixed with 2 biodegradable 2.7-mm pins (Rigid Fix; Ethicon, Mitek Division, Norderstedt, Germany) crossing the bone block perpendicular and 10 BPTB grafts fixed with conventional biodegradable interference screws (Absolute Absorbable Interference Screw; Innovasive Devices, Marlborough, MA) underwent ultimate single-cycle failure loading at a rate of 200 mm/min. The grafts were fixed to bovine tibia to simulate young human femoral bone density. Failure mode, displacement before failure, and ultimate failure load were tested with a testing machine. The pullout force was in line with the bone tunnel to simulate a worst case scenario. Results: The failure mode for cross pins was either fracture of the bone block (5 specimens) or fracture of the articular pin (5 specimens). The failure mode for interference screws was slippage past the screw in all specimens. In the single cycle loading test, the mean yield load for the biodegradable pins was 400.2 (± 122.4) N, maximum load, 524.6 (± 136.6) N, with a mean stiffness of 155.2 (± 32.4) N/mm. The yield load at failure for the interference screw was 402.7 (± 143.9) N, maximum load 515.7 (± 168.5) N with a mean stiffness of 168 (± 42) N/mm. Conclusions: Fixation of a BPTB graft with 2 biodegradable 2.7-mm pins (Rigid Fix) leads to primary stability that is comparable to fixation with biodegradable interference screws.     

The EndoPearl device increases fixation strength and eliminates construct slippage of hamstring tendon grafts with interference screw fixation

Purpose: The EndoPearl (Linvatec, Largo, FL), a biodegradable device to augment the femoral interference screw fixation of hamstring tendon grafts has been developed. The first objective of this study was to compare the initial fixation strength of quadrupled hamstring tendons and biodegradable interference screw fixation with and without the application of the EndoPearl device. The second objective was to determine the influence of the EndoPearl device on the fatigue behavior under incremental cyclic loading conditions in a simulation of critical fixation conditions. Type of Study: Biomechanical study. Methods: Fresh human hamstring tendons were harvested and grafts were fixed with biodegradable poly-L-lactide interference screws. Twenty proximal calf tibias were used to compare the initial fixation strength of the study and the control group. In the study group, the EndoPearl device was secured to the graft using two No. 5 Ethibond sutures (Ethicon, Somerville, NJ). Specimens were loaded until failure in a materials testing machine. For cyclic testing, human hamstring tendons and 20 distal porcine femurs were used. Critical graft fixation conditions were simulated by increasing tunnel diameter 2 mm over the graft diameter. Grafts were loaded progressively in increments of 100 N until failure; 100 cycles were applied per load increment. Results: Graft fixation with the additional EndoPearl device had a significantly higher maximum load to failure (658.9 ± 118.1 N v 385.9 ± 185.6 N, P =.003) and stiffness (41.7 ± 11 N/mm v 25.7 ± 8.5 N/mm). Graft fixation with the EndoPearl device sustained a significant higher total number of cycles (388.5 ± 125.6) compared with the control group (152.8 ± 144.9, P =.002). Conclusions: We demonstrated that the augmentation of a hamstring tendon graft with the EndoPearl device increases interference screw fixation strength significantly. Under dynamic loading conditions, specimens of the study group sustained substantially higher loads and a larger number of cycles, which indicates a greater resistance to graft slippage. The application of the EndoPearl device may also allow for a secure soft-tissue graft fixation with interference screws in cases of critical fixation conditions.Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 17, No 4 (April), 2001: pp 353–359     

Comparison of metal versus absorbable implants in tension-band wiring: a preliminary study

The strength of tension-band wiring using bioabsorbable materials versus metal implants was assessed with a rabbit knee fusion model. Ten rabbit knees were osteotomized and rigidly fixed using a tension-band technique: five with metal implants (2 pins and 24-gauge wire) and five with absorbable implants (2-mm pins [Bionx, Blue Bell, Pa] and 1 Maxon [Davis and Geck, Danbury, Conn]). Biomechanical testing of the fixation strength was completed using a servohydraulic mechanical testing machine and a specifically designed four-point bending jig. The parameters assessed were maximal load, relative stiffness, displacement, and bending moment of the constructs. Results of the biomechanical testing showed no statistical difference between the constructs on any of the parameters assessed.     

Bioabsorbable thread for tight tying of bones

The purpose of this research was to develop a bioabsorbable thread for tight fixation of fractured bones and to examine its mechanical performance in an in-vitro simulation study. The thread is a blend of bioabsorbable poly(L-lactic acid); (PLLA) and poly(ε-caprolactone); (PCL) fibers and can be tightly connected by fusion welding of the PCL fibers. The tying strength of the PLLA-PCL blend thread was 39.7 N, which was comparable to that of stainless steel wire. A testing machine was fabricated to measure the fatigue strength of the tying by simulating bone fixation. The results showed that metal wires always failed because of breakage within 25 000 loading cycles, whereas the blend threads did not fail until 50 000 loading cycles. The looseness of tying for simulated bone fixation by the blend thread was within 1mm even after 50 000 loading cycles. In-vivo testing using rats revealed that the blend thread did not cause any severe inflammatory reaction. Received for publication on March 15, 1999; accepted on July 7, 1999     

Comparison of bioabsorbable interference screws and posts for distal fixation in anterior cruciate ligament reconstruction

Comparison of the results of bioabsorbable interference screws and posts for hamstring graft distal fixation in ACL reconstructions are presented. The results of 20 patients with bioabsorbable screws were compared to 22 patients with posts. The assessement was based on Lysholm-Gillquist and Marshall scores and the KT-1000 device. In the study group the points gained were 38.9 in the Lysholm-Gillquist and 12.89 in the Marshall scale. The average KT-1000 difference was 2.46 mm. In the control group the points gained were 32.93 in the Lysholm-Gillquist and 11.47 in the Marshall scale. The average KT-1000 difference was 2.5 mm. There were 14 patients in the study group with interference screw problems; in 2 the implants were removed. (1) There are no differences in outcome using bioabsorbable interference screws and posts for distal fixation of hamstring ACL grafts. (2) The lack of bioabsorbtion with poly L-lactide interference screws is frequent and causes problems.     

Top tips for RIGIDfix femoral fixation

The use of pin fixation for grafts in the femoral tunnel in anterior cruciate ligament (ACL) reconstruction is becoming more popular. The transtibial stiff femoral guides are necessary to ensure that the pins fix the graft. However, the cross pins can sometimes miss the femoral tunnel. As a result of some technical problems that we encountered, we introduced an extra step in the technique of the Mitek RIGIDfix ACL Graft Fixation System (Mitek Products, Ethicon, Edinburgh, UK). This article suggests some tips for fixing problems that arise in cases in which the graft is accidentally missed with the cross pins.     

Interference screw position and hamstring graft location for anterior cruciate ligament reconstruction

Anterior cruciate ligament reconstruction with hamstring tendon graft and interference screw fixation has recently been considered. Concerns for the use of interference screws with soft tissue grafts include damage to the graft during screw insertion, decreased fixation strength, and a decrease in the bone-tendon contact area for healing within the tunnel when the screw is placed in an eccentric position. This last concern could be addressed by placing the interference screw centrally between the four limbs of the hamstring graft. The purpose of this study was to determine the mode of failure, the pullout force, and graft slippage before graft fixation failure of hamstring tendons fixed with an interference screw positioned eccentrically in relation to the hamstring tendons verses an interference screw positioned centrally between the four graft limbs. The semitendinosus and gracilis tendons were harvested from six, fresh cadaveric specimens. Each tendon was divided into two segments of equal length. Both the semitendinosus and gracilis tendon segments were looped to form four strands. The specimens were then fixed with a bioabsorbable interference screw in the two different positions and pulled from a standardized polyurethane foam. All tendons in both groups failed by pulling out from between the interference screw and tunnel, regardless of the screw position. No tendon was cut by the screw in either group. There was no significant difference between the forces required to produce specific amounts of graft slippage between the two fixation techniques tested. There was no significant difference between the average total slippage at maximum pullout, 11.8 mm for the screw placed in the eccentric position and 13.7 mm for the screw placed in the central position. The maximum pullout force averaged 265.3 N for the screw placed in the eccentric position, and 244.7 N for the screw placed in the central position; these values were not significantly different. Placement of the interference screw in the central position did not compromise strength and it improves graft contact within the bone tunnel. Interference screw fixation, when applied against a bone plug, has been shown to consistently have a pullout force of more than 400 N.Arthroscopy 1998 Jul-Aug;14(5):459-64     

Chondral injury after arthroscopic meniscal repair using bioabsorbable Mitek Rapidloc meniscal fixation

Arthroscopic meniscal repair is a commonly performed procedure in clinical practice. With improvements in bioabsorbable implants, all-inside techniques have increased in popularity. The Mitek RapidLoc meniscal fixation implant may be used to fix reparable meniscal tears arthroscopically without requiring an additional incision. We report 2 potential complications associated with this implant: chondral injury causing femoral grooving and recurrent meniscal tear 4 months after initial surgery.     

Pullout strengths of self-reinforced poly-L-lactide (SR-PLLA) rods versus Kirschner wires in bovine femur

OBJECTIVE: To determine the relative amount of fixation of self-reinforced poly-L-lactide (SR-PLLA) rods and Kirschner wires in bovine cancellous bone by comparing their pullout strength DESIGN: An in vitro laboratory study was performed using bovine femurs. Ten two-millimeter-diameter pins of each type were inserted into cancellous bone and then pulled out, using a material testing machine. The maximum force (pullout strength) was selected over other measurements to compare the amount of fixation of the two types of pins. All of the pins were retrieved for microscopic analysis. A paired t test was performed to analyze the differences between the pullout strength of the two types of pins. SETTING: Orthopaedic Bioengineering Laboratory, University of Louisville School of Medicine, Louisville, Kentucky, U.S.A. SPECIMENS: Two young fresh bovine distal femurs, ten two-millimeter-diameter Kirschner wires, ten two-millimeter-diameter bioabsorbable SR-PLLA rods MAIN OUTCOME MEASUREMENTS: Pullout strength in Newtons, and microscopic pin surface aspect after insertion. RESULTS: Significant differences were noted between the maximum force required to remove the two types of pins (p < 0.01) The K-wire mean pullout force was 37.7 N (SD 13.6), and the SR-PLLA rod mean pullout force was 53.6 N (SD 19.3). Microscopic analysis indicated surface modification only on the SR PLLA rods. DISCUSSION: SR-PLLA composites have shown comparable clinical results to their metallic counterparts. In this study, the pullout strength of SR-PLLA rods was compared with that of conventional K-wires. A significant difference (p < 0.01) favoring bioabsorbable pullout strength was noted. The bioabsorbable pin surface modification during insertion is an interesting finding that warrants further investigation as a potential source of improved fixation. CONCLUSION: SR-PLLA rods retain their hold in bovine cancellous bone better than K-wires. This finding offers to the orthopaedic surgeon more information about new pin fixation methods.     

Response of hamstring and patellar tendon grafts for anterior cruciate ligament reconstruction during cyclic tensile loading

The efficacy of anterior cruciate ligament (ACL) reconstruction in the knee using hamstring tendon or patellar tendon grafts is thought to depend on the relative amounts of graft elongation, or creep, following postoperative rehabilitation. In this study, the creep responses of the tendinous portions of these two graft types were compared during 1 hour of cyclic loading to 200 N at 1 Hz. In the hamstring tendon grafts, strains were measured in both the tissue and in the length-augmentation tape to identify the relative contribution of this particular graft fixation to overall creep. Differences in tissue strain between graft types during cyclic loading were not statistically significant. For both types of grafts, overall graft length significantly increased after 3600 cycles while tissue creep was not significant. The greatest creep in the hamstring tendon grafts occurred at the tissue-tape interface, indicating a potential disadvantage of this composite graft construct.     

In vitro comparison of standard and knotless metal suture anchors

Purpose: Clinical experience after failed Knotless suture anchor (Mitek, Westwood, MA) fixations suggested that the Knotless anchor provides considerably less fixation stability than a standard metal anchor. The purpose of this study was to analyze soft tissue fixation to bone comparing a standard and a Knotless metal suture anchor. Type of Study: In vitro study. Methods: The Mitek GII and Mitek Knotless suture anchors were tested on 7 human cadaveric fresh-frozen glenoids. The anchors were inserted into the glenoid rims, and the sutures of the anchors were fixed to a metal hook attached to the cross-head of a testing machine. Cyclic loading was performed. The gap formation between the metal hook and the glenoid rim, the ultimate failure loads and the modes of failure were determined. Results: The mean gap formation was significantly greater for the Knotless anchor (3.8 ± 1.4 mm) than for the GII anchor (2.4 ± 0.5 mm) after 25 cycles with 50 N repeated load (P = .04). The largest gap of a Knotless fixation was 5.3 mm compared with 3.0 mm for the GII. The ultimate failure load was not significantly different for the Knotless anchor (179 N) and for the GII anchor (129 N). Both anchors failed by either rupture of the suture material or by pullout of the anchors. Conclusions: The GII anchor allows significantly less displacement than the Knotless anchor. Ultimate tensile strength and mode of failure are similar. Greater displacement results in larger gap formation between the soft tissue and the bone. This might weaken and jeopardize the repair. Clincial Relevance: If reattached soft tissues are subjected to postoperative loading, gap formation may result when using the Knotless anchor. For these conditions, suture fixation with knots may be used instead.     

Suture anchor strength revisited

The rapid proliferation of suture anchors continues. Our prior report on the pullout strength of 14 different anchors is supplemented by a similar test conducted on 8 additional anchors. Comparative data on modes of failur and failure strengths (ultimate loads to failure) for these new devices are compared statistically with the previously tested anchors. In a fresh never-frozen porcine femur model, 10 samples of each of the additional anchors tested were threaded with stainless steel sutures and inserted into three different test areas (diaphyscal cortex, metaphyseal cortex, and a cancellous trough). Tensile stress parallel to the axis of insertion was applied at a rate of 12.5 mm/s by an Instron 1321 testing machine (Instron Corp., Canton, MA) until failure and mean anchor failure strengths calculated. The anchors tested were the MItek G2 as a control, miniMitek, Mitek Superanchor, Mitek Rotator Cuff anchor (Mitek Products, Westwood, MA), Innovasive Devices Radial Osteal Compression device (Innovasive Devices, Hopkinton, MA), Arthrex Fastak (Arthrex Inc, Naples, FL), Arthrotek miniHarpoon (Arthrotek, Warsaw, IN), Orthopedic Biosystems PeBA 3 and PeBA 5 (Orthopedic Biosystems, Scottsdale, AZ), and AME 5.5 screw (American Medical Electronics, Richardson, TX). Failure mode (anchor pullout, suture eyelet cut out, or wire breakage) was generally consistent for each anchor type. The size of insertion hole is clinically important and each anchor's performance was evaluated as a function of is minor diameter or drill hole. For screw anchors, the larger the minor diameter of the screw, the higher the mean failure strengthsin all three test areas (P = .001). However, larger drill holes for non-screw anchors resulted in lower mean failure strengths in cancellous bone (P = .03) and diaphyseal cortex (P < .005).     

RigidFix Femoral Fixation: A Test for Detecting Inaccurate Cross Pin Positioning

The RigidFix Cross Pin System (DePuy Mitek, Raynham, MA) is a popular technique for femoral fixation of graft in ACL reconstruction. In some cases, though, cross pins miss the femoral tunnel resulting in inadequate proximal graft fixation. We present a simple test to detect the incorrect placement of cross pins. The pinholes are drilled through the guide frame, leaving 2 sleeves for cross pins insertion. The manufacturer’s recommendations, at this stage, are to reinsert the femoral tunnel guidewire, remove the guide frame, and insert the graft without verifying accurate pinhole positioning. We reinsert the femoral tunnel guidewire without removing the guide frame, and a second guidewire is introduced through each of the sleeves in turn. In case of appropriate pinhole placement, the 2 guidewires will meet in the cannulated rod of the guide frame and the surgeon will have the metal-to-metal feeling. If the pinhole misses the femoral tunnel, the 2 guidewires will not meet and the surgeon will not have the metal-to-metal feeling. In our practice, 9 cases of inaccurate pinhole placement were detected with this test and verified by direct vision of the femoral tunnel with the arthroscope. We find this test simple, reliable, and not time consuming.     

Biomechanical evaluation of a bioabsorbable expansion bolt for hamstring graft fixation in ACL reconstruction: an experimental study in calf tibial bone

Introduction: The purpose of our study was to evaluate and compare the primary fixation strength of a novel bioabsorbable two shell expansion bolt (EB) with that of a well-established interference screw-fixation technique in hamstring reconstruction of the anterior cruciate ligament. Materials and methods: Thirty calf tibia plateaus (age 5–6 months) were assigned to three groups: In group I (n=10) triple-stranded hamstring grafts were fixed with titanium interference screws (7 mm thread / 8 mm head × 25 mm). Specimens of group II (n=10) received bioabsorbable poly-L-lactide interference screws (8×23 mm). In group III (n=10), the grafts were fixed using bioabsorbable poly-D,L-lactide expansion bolts (5.8/8.5/10 mm × 35 mm). The tensile axis was placed parallel to the bone tunnel. The construction was then loaded until failure under a displacement rate of 1 mm per second. Results: There were no significant differences concerning the maximum pullout force (group I: 357 N ± 61; group II: 326 N ± 92; group III: 343 N ± 55). In case of the expansion bolt, we found the stiffness to be higher (61 N/mm) when compared to group I (48 N/mm), and group II (52 N/mm) (P<0.01 I vs. III). Using interference screws, we were able to demonstrate a strong correlation between torque and pullout forces (group I: r ²=0.7; group II: r ²=0.92). Ruptures of the suturing material occurred only in groups I and II. Conclusion: We conclude that hamstring graft fixation, using the presented expansion bolt, demonstrates fixation strength similar to the established screw fixation and can therefore be regarded as a reasonable alternative fixation method. Especially, since some specific disadvantages of screw fixation can be prevented by application of the bolt fixation.     

The effect of interference screw diameter on soft tissue graft fixation

Tibial fixation of soft-tissue grafts is a weak link in anterior cruciate ligament reconstruction. Previous studies have examined varying interference screw lengths, screw types and tunnel sizes as means to improve graft fixation. We hypothesized that increasing interference screw diameter would significantly increase the maximum load to failure of the graft and decrease the graft's initial slippage. Seventy tibialis anterior and tibialis posterior tendons were divided, looped, trimmed, and sutured to simulate 4-strand hamstring grafts. These grafts were then inserted into composite bone blocks having pre-drilled 8 mm holes and fixed with 8 mm, 9 mm, 10 mm, 11 mm, or 12 mm interference screws. Fourteen grafts were tested for each screw size. The graft was first cyclically loaded from 50 N to 250 N at 0.3 Hz for 100 cycles to measure graft slippage. The graft was then tested to failure at 0.5 mm/sec to determine the maximum load to failure and mode of failure. Graft slippage was not affected by screw diameter. Maximum load to failure increased with increasing screw diameter up to 11 mm; 11 mm screw fixation was 20% stronger than 8 mm screw fixation. In this model, no increase in graft fixation was seen in by increasing interference screw diameter beyond 3 mm of the tunnel diameter.     

Fixation of tendon grafts for collateral ligament reconstructions: a cadaveric biomechanical study

PURPOSE: To compare the biomechanical properties of 4 methods of fixation of tendon grafts to bone as used for ligament reconstructions. METHODS: Thirty-two metacarpals were harvested from fresh-frozen cadavers and stripped of soft tissue. Flexor tendons were harvested from the same cadavers and cut into 2-mm-wide strips. Each tendon was fixed to a metacarpal head at the site of origin of a collateral ligament. Four different methods of fixation were tested. In group 1 the tendon was fixed to the bone with a 4.0-mm Arthrex bio-tenodesis interference screw (Arthrex, Inc., Naples, FL). In group 2 the tendon was passed through a bone tunnel and fixed with a 3.2-mm mini-Acutrak screw (Acumed, LLC, Hillsboro, OR) that was inserted in interference mode. In group 3 the tendon was passed through a bone tunnel and fixed with sutures tied over a polyethylene button. In group 4 the tendon was fixed with a mini-Mitek bone suture anchor (Mitek Worldwide, Norwood, MA). All specimens were clamped into a linear loading machine and loaded until failure. Statistical analysis was performed by 1-way analysis of variance testing. RESULTS: The differences in maximal tensile strength and stiffness were statistically significant when comparing any 2 groups. The Arthrex biotenodesis interference screw was the strongest and stiffest fixation method, followed by the Acutrak screw inserted in interference mode. Next was the suture tied over a button method. The mini-Mitek bone suture anchor was the weakest. CONCLUSIONS: Interference screw fixation of tendons to bone has statistically significant higher pullout strength and stiffness than 2 other commonly used fixation methods. The use of interference screws for fixation of tendon grafts to bone for hand ligament reconstructions is a promising new surgical technique.