Das „European Vision Institute“

The European Vision Institute EEIG (EVI) creates a new legal entity based on Community law to facilitate and encourage cross-border co-operation in vision research. Its major objectives are to conduct and support research, training, health information dissemination and other programmes with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight and the special health problems and requirements of the blind and visually disabled. EVI aims to foster centres in the EU in capacity building for innovative projects, to increase the flexibility, attractiveness and competitiveness of research careers, especially for young researchers. In addition, EVI will serve to co-ordinate activities with patient organisations and to build a pan-European platform for clinical trials.     

The Contrast Sensitivity Function in Low Vision

The contrast sensitivity of 51 low vision patients (95 eyes) showed a substantial decrease in all spatial frequencies. The peak contrast sensitivity was shifted to 1 C/D from the normal 3-4 C/D. The high-frequency cut off is correlated to the visual acuity positively. Of the 33 patients, the preferred eye was the eye with better peak sensitivity in 28 patients (84%), while the preferred eye was the eye with better visual acuity in 22 patients (66%). It seems that the peak sensitivity is more important than visual acuity in determining eye preference. It provides a useful information for the clinician to determine which eye to train with low vision aids. Forty patients among 46 patients (87%) with RFN (Recognized Frequency Number) >3 are able to read No.5 reading card, while 5 patients among 5 patients with RFN<3 are not able to read No.5 reading card. The contributions of CSF to the low vision are evaluated.     

The Etiology of Vision Impairment in Target Population

Purpose: research the etiology of vision impairment in target persons over 45 years old in Doumen county , Guangdong province.Methods: Depending on the prevalences of the blindness among the person aged over 50 years, the theoretic sample rate is 1 000/4 8733×100%=2. 05%. The 8 districts were divided into 3 parts according to the local economic situation and the proportion of the population in the areas. In fact, the sampling rate is 932/ 10055 = 88.34%.Results:W'e found that impairment <0. 3 accounted for 10. 94%. The prevalence of bilateral blindness and low vision was 1. 61% and 3. 22%, respectively. Both prevalences of blindness and low vision were increased with age. The leading cuase of blindness was cataract (45. 2%). The second was corneal opacity (16. 7% ). Prevalentces of the low vision and the blindness were higher in females than in males (P<0. 005).Conclusions: Curable and preventable diseases were the leading cause for the blindness (70%). Prevalences of blindness and the low vision incre     

皮克眼科检查手机应用(Peek Vision)

全世界有2.85亿人在视觉上受损,其中3900万人是盲人,百分之80的失明是可以避免的.不过,问题是大部分眼疾患者都在发展中国家或者偏远乡村,缺医少药,眼科医师更是稀缺资源.在最需要的领域,病人没有获得诊断或治疗.     

Vision impairment and older drivers: who's driving?

AIM: To establish the association between impaired vision and drivers' decisions to stop driving, voluntarily restrict driving, and motor vehicle accidents. METHODS: Driving related questions were included in a population based study that determined the prevalence and incidence of eye disease. Stratified random cluster samples based on census collector districts were selected from the Melbourne Statistical Division. Eligible participants aged 44 years and over were interviewed and underwent a comprehensive ophthalmic examination. The outcomes of interest were the decision to stop driving, limiting driving in specified conditions, and driving accidents. The associations between these outcomes and the legally prescribed visual acuity (<6/12) for a driver's licence were investigated. RESULTS: The mean age of the 2594/3040 (85%) eligible participants was 62.5 (range 44-101). People with visual acuity less than 6/12 were no more likely to have an accident than those with better vision (chi(2) = 0.175, p>0.9). Older drivers with impaired vision, more so than younger adults, restrict their driving in visually demanding situations (p<0.05). Of the current drivers, 2.6% have vision less than that required to obtain a driver's licence. The risk of having an accident increased with distance driven (OR 2.57, CL 1.63, 4.04 for distance >31 000 km) but not with age. CONCLUSION: There was no greater likelihood of self reported driving accidents for drivers with impaired vision than those with good vision. While many older drivers with impaired vision limit their driving in adverse conditions and some drivers with impaired vision stop driving, there are a significant number of current drivers with impaired vision.     

Quantitative Evaluation of Flicker ERG Waveforms in Low Vision Patients

Flicker electroretinograms(FERGs)of 30Hz were recorded for 46eyes(23 cases)of low vision,including 38 eyes with retinal diseases and 8eyes with optic neuropathy,and for 39 normal eyes(33 cases).The recordedwave forms were analysed by two methods:(1)to measure the peak to peakamplitude and pseudophase directly,and(2)to measure the amplitude andphase of fundamental response component(30Hz)by discrete Fourier trans-form(DFT).The abnormality ratios between these two methods were com-pared in low vision patients.All the eyes with optic neuropathy showed normalflicker ERG,the abnormality ratios of directly measured amplitude and theamplitude by DFT were 60.9% in 28 eyes and 71.7% in 33 eyes with retinal dis-eases respectively,the difference being no statistically significant(P>0.05),while the abnormality ratios of directly measured pseudo-phase and the phaseby DFT were 60.9% in 28 eyes and 82.6% in 38 eyes with retinal diseasesrespectively,the difference being statistically significant(P<0.05).Theseresults suggest that FERGs are an objective way to test the retinal function,andDFT for flicker ERGs are more useful in quantitative evaluation of the retinalfunction.Eye Science 1992;8:122-125.     

The Normal Color Vision Evaluated With FM 100-hue Test

One hundred and twenty normal subjects (240 eyes) agedfrom 10 to 69 were tested with FM 100-hue test.They were divided into6 groups according to their age.It was shown that there were no statisti-cally significant difference in the total error score (TES) between the malesand females or between the right and left eyes,but there existed some rela-tionships between the TES and age.The total error score (TES) was thelowest in the 20-29 age group and increased gradually with aging.Theanalysis of the partial error score (PES) in each age group showed that thePES was the lowest in 20-29 age group and that the larger PES appearedaround the axis of titan with age increasing.Eye science 1993;9:158-160.     

The Objective Measure of Color Vision in Primary Open Angle Glaucoma

Purpose: To objectively evaluate the clinical application of color pattern reversal visual e-voked potential (CPR-VEP) on primary open angle glaucoma (POAG). Methods: CPR-VEP and FM 100-hue test were performed in 31 eyes with POAG and 33 normal eyes. Color pattern stimulation was presented by color monitor controlled by computer program. The reversal rate of the stimulating pattern was 2 Hz and the spatial frequency of the stimulating was 0.53 cycle/degree. The color stimulating pattern include White /Black , Red/Black , Green/Black , Blue/Black , Yellow /Black , Red/Green and Blue /Yellow . Results : CPR-VEP P1 latencies were obviously prolonged in POAG group in comparison with normal control group in equiluminance. All CPR-VEP P1 amplitudes, except Blue/Black P1 amplitude, show no differences between POAG group and normal control group . Conclusion: P1 latencies of all CPR-VEP and P1 amplitude of Blue/Black CPR-VEP were parameters for identifing acquired dyschromatopsia caused by POAG. The results sho     

How Effective is Low Vision Service Provision? A Systematic Review

Visual impairment is a large and growing socioeconomic problem. Good evidence on rehabilitation outcomes is required to guide service development and improve the lives of people with sight loss. Of the 478 potentially relevant articles identified, only 58 studies met our liberal inclusion criteria, and of these only 7 were randomized controlled trials. Although the literature is sufficient to confirm that rehabilitation services result in improved clinical and functional ability outcomes, the effects on mood, vision-related quality of life (QoL) and health-related QoL are less clear. There are some good data on the performance of particular types of intervention, but almost no useful data about outcomes in children, those of working age, and other groups. There were no reports on cost effectiveness. Overall, the number of well-designed and adequately reported studies is pitifully small; visual rehabilitation research needs higher quality research. We highlight study design and reporting considerations and suggest a future research agenda.     

Detection of Gene Alteration for Color Vision Defects by Polymerase Chain Reaction

According to the fact that the abnormalities of visual pigment genes were always involved in the changing of the exon 5, two oligonucleotide primers were designed to amplify the exon 5 of red pigment gene and green pigment gene. After electrophoresis of the PCR products digested with Rsal or Sau3A, the DNA fragments from the exon 5 of red pigment gene (RPG) and green pigment gene (GPG) were separated since there are different restriction endonuclease sites. On the other hand, we analyzed the exon 5 related fragment by Southern blot hybridization with probe out of the 3'end of the fourth in-tron of green pigment gene. The results of PCR are consistent with nucleic acid hybridization. PCR technique will be of value in prenatal evaluation and genetic counselling.     

Transient Daily Episodes of Vision Loss Due to Parkinson’s Disease

Visual complaints are common in Parkinson’s disease (PD), but transient visual loss has not previously been defined as a feature of parkinsonian-related disease. We report a patient with recurrent daily episodes of transient and disabling visual loss due to PD-related non-motor fluctuation. During his visit, he experienced one such episode, which allowed for close observation and examination during and after the visual loss. Implications for localization of the visual loss are reviewed in the context of visual pathway disturbances in PD.     

Spot Vision Screener视力筛查仪在儿童视力筛查中的应用分析

目的：通过对Spot Vision Screener视力筛查仪在儿童视力筛查中的应用探讨,寻求一种新型、可靠、方便的儿童屈光状况筛查方法。方法：对我院门诊进行筛查的2~9岁儿童共87例174眼进行屈光检查,并将结果与电脑显然验光结果进行对比。结果：Spot Vision Screener视力筛查仪与电脑显然验光结果对比,除右眼球镜值存在统计学差异外,两种方法测量的左眼球镜值、双眼柱镜值及柱镜轴向、双眼等效球镜值均无统计学差异(P>0.05)。结论：Spot Vision Screener视力筛查仪操作简单易行,儿童配合度好,不失为临床对儿童进行视力筛查的一种新方法。     

A Study of Spectral Electroretinogram of Color Vision Defects Due to Macular Diseases

Studies of spectral electroretinograms in central serous retinopa-thy (CSR) and hereditary macular degeneration (HMD) showed that the b-wave amplitudes of most wavelengths of CSR were significantly decreased as compared with normal controls, and those of HMD were obviously lower than the normal values. Patients of HMD with type-A color vision defects (CVD) had primarily a reduction of b-wave amplitudes in the full spectrum of 480-620 nm, and patients with type- I CVD a reduction of b-wave amplitudes wavelengths of 480 - 560 nm. These differences might reflect differences in damages to the medium-and long-wave length. Eye Science 1994: 10: 163-167.     

Why Poor Vision Despite an Attached Retina following Primary Vitrectomy in Egyptian Patients?

Objective: To correlate findings on spectral domain optical coherence tomography (SD-OCT) and best-corrected visual acuity (BCVA) following primary vitrectomy for rhegmatogenous retinal detachment (RRD). Methods: In this prospective, interventional, non-randomized case series, 71 eyes with RRD of intermediate severity underwent primary vitrectomy followed by SD-OCT one month later. Main outcome measures were inner segment/outer segment (IS/OS) junction line and external limiting membrane (ELM) disruption. Results: All patients achieved reattachment with mean BCVA of 0.77 ± 0.36 logMAR. There was statistically significant correlation between each length of IS/OS and ELM defect on the one hand, and BCVA on the other hand. Conclusion: The extent of IS/OS and ELM disruption explains the poor visual outcome in successful RD surgery with an otherwise normal foveal contour.