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1.
目的 观察眼内窥镜下睫状体光凝术(endoscopiccyclophotocoagulation,ECP)联合白内障超声乳化及人工晶状体植入术(phacoemulsificationandintraocularlens,Phaco+IOL)后不同范围睫状体光凝对前房蛋白质浓度、TNF-α含量、IL-1β含量改变的影响,并分析对前房炎症反应的影响。方法 将24只(48眼)成功建立慢性青光眼模型的灰兔随机分成A组、B组、C组、D组,其中A组、B组、C组分别给予180°、270°、360°三种不同范围睫状体光凝的ECP+Phaco+IOL手术,D组给予小梁切除(trabeculectomy,TRAB)+Phaco+IOL手术,分别对术前、术后房水蛋白质浓度、TNF-α、IL-1β含量检测;观察术后炎症反应;术中、术后并发症的发生情况。结果 A组、B组、C组、D组术后1d、7d、14d房水中蛋白质浓度、TNF-α含量、IL-1β含量升高,30d基本恢复至术前水平;术前及术后1d、7d、14d、30d房水中蛋白质浓度、TNF-α含量、IL-1β含量:不同组间含量随时间变化趋势相同,差异均无统计学意义(P=0.153、0593、0.203);相同时间点不同组间含量差异均无统计学意义(均为P>005)。4组术后蛋白质浓度与前房炎症反应均呈正相关(均为P<0.05)。结论 ECP+Phaco+IOL与TRAB+Phaco+IOL两种不同联合手术方式术后早期均引起蛋白质浓度、TNF-α和IL-1β含量升高,30d基本恢复正常;而在同一时间点不同的手术方式对蛋白质浓度、TNF-α和IL-1β含量影响不大。 相似文献
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目的 探讨23G前段玻璃体切割联合白内障超声乳化手术治疗浅前房低角膜内皮细胞密度(endothelialcelldensity, ECD)白内障的疗效及安全性。方法 根据患者自愿原则,将2012年1月至2015年12月在郑州大学第二附属医院接受手术治疗的30例(34眼)ECD<1000mm-2的浅前房白内障患者分为联合手术组和Phaco组。联合手术组16例(19眼),行23G前段玻璃体切割联合白内障超声乳化术;Phaco组14例(15眼),行单纯白内障超声乳化术。术后1d、1周及3个月检查两组患者最佳矫正视力、角膜水肿程度,同时记录术前及术后3个月ECD,观察角膜水肿消退时间、术中及术后并发症。结果 术后1d,联合手术组最佳矫正视力较术前显著增高,差异有统计学意义(P<0.05)。术后1周及3个月,两组最佳矫正视力均较术前显著增高,差异均有统计学意义(均为P<0.05)。术后1d及1周,联合手术组最佳矫正视力均优于Phaco组,差异均有统计学意义(均为P<0.05)。术后1d,联合手术组以1级角膜水肿为主,Phaco组以2级角膜水肿为主,两组角膜水肿程度差异有统计学意义(P<0.05)。联合手术组角膜水肿平均消退时间为1.0d,小于Phaco组的4.0d,差异有统计学意义(P<0.05)。术后3个月,联合手术组角膜内皮细胞丢失率为(7.86±0.76)%,低于Phaco组的(13.39±0.47)%,差异有统计学意义(P<0.05)。结论 23G前段玻璃体切割联合白内障超声乳化术安全性好,角膜内皮细胞损伤小,术后角膜水肿轻,早期视力恢复快,适用于浅前房低ECD白内障患者。 相似文献
3.
目的 应用Orbscan-Ⅱ眼前节分析系统探讨飞秒激光辅助的准分子激光原位角膜磨镶术(femtosecondlaserinsituker-atomileusis,Fs-LASIK)和飞秒激光小切口透镜切除术(smallincisionlenticuleextraction,SMILE)术后角膜后表面高度的变化。方法 前瞻性随机对照研究。选择2014年5月至11月于我院行激光角膜屈光手术的近视患者(等效球镜度数≤ -6.00D)60例(119眼),随机分成A、B两组,每组30例(A组59眼,B组60眼)。A组施行SMILE,B组施行Fs-LASIK,观察术后视力、屈光度等的变化。采用Orbscan-Ⅱ眼前节分析仪,分别于术前、术后1个月对术眼进行眼前节图像采集,记录角膜后表面Diff值变化并进行对比。结果 术后1个月两组患者裸眼视力均比术前提高,但两组间相比差异无统计学意义(P>0.05)。术前最佳矫正视力与术后1个月相比差异均无统计学意义(均为P>0.05),术后最佳矫正视力两组间相比差异亦无统计学意义(P>0.05)。术前及术后1个月A、B两组屈光度相比差异均无统计学意义(均为P>0.05)。两组后表面Diff值均较术前显著增加,其中A组术前、术后分别为(0.027±0.001)mm和(0.059±0.001)mm(P<0.05);B组术前、术后分别为(0.029±0.001)mm和(0.054±0.002)mm(P<0.05),但A、B两组术后角膜后表面Diff值增加量相比差异无统计学意义(P>0.05)。结论 SMILE和Fs-LASIK矫正近视均安全有效,术后1个月角膜后表面高度均部分前移,其远期变化有待进一步探索。 相似文献
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目的 比较1.8mm和3.0mm两种白内障手术切口术后泪膜及角膜规则性的变化。方法 选取2014年11月至2015年10月行白内障超声乳化吸出术的年龄相关性白内障患者48例(62眼),根据患者对人工晶状体的选择分为:A组24例(30眼)行1.8mm透明角膜微切口白内障超声乳化术,B组24例(32眼)行3.0mm透明角膜切口白内障超声乳化术。比较术前及术后1d、7d、1个月、3个月的泪膜破裂时间(break-uptime,BUT)、基础泪液分泌(SchirmerⅠ test,SⅠt)、角膜荧光素染色评分(corneafluoresceinstaining,FLS)、干眼主观症状评分、角膜表面规则性指数(surfaceregularityindex,SRI)及角膜表面非对称性指数(surfaceasymmetryindex,SAI)。结果 术后1d、7dB组BUT均短于A组(均为P<0.05)。术后1dB组SⅠt低于A组(P<0.05)。术后1d、7d、1个月B组FLS均高于A组(均为P<0.05)。术后1d、7dB组干眼主观症状评分均高于A组(均为P<0.05)。术后1d、7d、1个月B组SAI、SRI均高于A组(均为P<0.05)。A组BUT、FLS、干眼主观症状评分、SAI于术后1个月恢复至术前状态,SⅠt和SRI于术后7d恢复至术前状态;B组各项结果均于术后3个月恢复至术前状态。结论 1.8mm切口较3.0mm切口白内障超声乳化术后干眼症状更轻,泪膜功能及角膜规则性恢复更快。 相似文献
5.
目的 比较2.0mm微切口飞秒激光角膜基质透镜取出术(2.0mmsmallincisionlenticuleextraction,2.0mmSMILE)与飞秒激光辅助的LASIK(laserinsitukeratomileusiswithfemtosecondlaser,FS-LASIK)矫正近视的疗效。方法 研究纳入行2.0mmSMILE的近视患者48例(96眼),同期行FS-LASK者50例(100眼),记录并比较两组术前及术后1d、1周、1个月、3个月及6个月的裸眼视力(uncorrectedvisualacuity,UCVA)、最佳矫正视力(bestcorrectedvisualacuity,BCVA)、屈光度、生活质量量表(qualityoflife,QOL)得分及手术满意度量表评分。结果 在术后1周以后SMILE组视力高于FS-LASIK组,且状态较FS-LASIK组更为稳定。术后1个月、3个月、6个月SMILE组UCVA≥术前BCVA的比例高于FS-LASIK组,差异均有统计学意义(均为P<0.05)。术后早期(术后1周)SMILE组存在1例过矫,而FS-LASIK组存在1例欠矫,但在术后1个月、3个月、6个月两组手术患者均在±1.00D范围内。术后平均角膜前表面形态变异指数及垂直不对称指数在各时间点均为FS-LASIK组大于SMILE组,差异均有统计学意义(均为P<0.05)。两组术前及术后6个月QOL得分组间比较,差异均无统计学意义(均为P>0.05),术后6个月QOL得分均较术前有所增加,且差异均有统计学意义(SMILE:t=-13.85,P=0.00;FS-LASIK:t=-13.21,P=0.00),而两组术后6个月QOL得分比较,差异无统计学意义(P>0.05)。两组均有较高的再次手术选择率及手术推荐率,并且未发生严重的并发症。结论 2.0mmSMILE与FS-LASIK均具有良好的有效性、稳定性以及可预测性,术后都可获得良好的视力及良好的生活质量,前者更好地保持了角膜前表面的形态。 相似文献
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目的 应用深层成像谱域光学相干断层扫描(enhanceddepthimagingspectral-domainopticalcoherencetomography,EDI-SDOCT)观察全视网膜光凝(panretinalphotocoagulation,PRP)对非增生性糖尿病视网膜病变(non-proliferativediabeticretinopa-thy,NPDR)患眼黄斑区脉络膜厚度的影响。方法 对35例(59眼)NPDR患者行PRP术,以42例(59眼)正常眼作为对照组。应用EDI-SDOCT分别在PRP术前和术后1周测量对照组和光凝组黄斑区各点位脉络膜厚度,比较术后1周较术前的变化,各点标记为:中心凹下脉络膜厚度(subfovealchoroidalthickness,SFCT),各扫描线上距离中心凹750μm、1500μm处的鼻侧脉络膜厚度(nasalchoroidalthickness,NCT)、颞侧脉络膜厚度(temporalchoroidalthickness,TCT)、上方脉络膜厚度(superiorchoroidalthickness,SCT)、下方脉络膜厚度(inferiorchoroidalthickness,ICT)、平均黄斑区脉络膜厚度(averagemacularchoroidalthickness,AMCT)。结果 光凝组术前、术后1周的SFCT、NCT750、TCT750、SCT750、ICT750、NCT1500、TCT1500、SCT1500、ICT1500、AMCT均明显低于对照组(均为P<0.05);术后1周SFCT和AMCT明显高于术前(均为P<0.05);除TCT750和TCT1500术后与术前无明显差异外(均为P>0.05),余各点位术后均明显高于术前(均为P<0.05)。其中10眼术后各值低于术前,2眼可观察到术后脉络膜血管孔径较术前增加。结论 NPDR会导致黄斑区脉络膜变薄,PRP术短期内能够明显增加黄斑区脉络膜厚度,同时一定程度上增加脉络膜的血管孔径。EDI-SDOCT是用于评价NPDR患者疗效和预后的有效无创检测手段。 相似文献
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目的 测量并观察生后12个月以内行先天性白内障摘出术患儿术后术眼中央角膜厚度(centralcornealthickness,CCT)及眼压(intralocularpressure,IOP)的变化。方法 选取26例(49眼)生后12个月内行白内障摘出术的先天性白内障患儿为观察组,按行手术时月龄分为三组:1组:月龄≤3个月,2组:3个月<月龄≤6个月;3组:6个月<月龄≤12个月。分别在术前、术后1个月、3个月、6个月时测量术眼CCT与IOP。另选取与各观察组最后一次随访时的患儿年龄与性别相匹配的相对正常眼婴幼儿作为对照组。结果 观察组术后1个月、3个月、6个月的CCT为(578.39±47.79)μm、(581.34±51.54)μm、(588.29±49.90)μm,均显著大于术前(563.56±37.14)μm及对照组(534.96±40.34)μm(均为P<0.05)。观察组术前、术后1个月、3个月、6个月IOP测量值间差异无统计学意义(P>0.05),观察组术后6个月IOP测量值大于对照组(P<0.05)。观察组术后6个月CCT与IOP线性相关(r=0.538,P=0.004)。结论 婴儿先天性白内障摘出术后早期的CCT显著大于正常同龄婴儿,且与IOP线性相关。 相似文献
8.
目的 比较负球差疏水性丙烯酸酯人工晶状体眼和零球差亲水性丙烯酸酯人工晶状体眼术后1个月术眼散射情况。方法 收集我院行超声乳化吸出联合人工晶状体植入术患者60眼,其中30眼植入负球差疏水性丙烯酸酯人工晶状体,定义为TecnisZA9003组;另外30眼植入零球差亲水性丙烯酸酯人工晶状体,定义为SofTecHD组。术后1个月使用欧卡斯测量各组客观散射指数(objectivescatteringindex,OSI)、调制传递函数截止空间频率(modulationtransferfunctioncutoff,MTFcutoff)、斯特尔比值(strehlratio,SR)。使用Pentacam测量各组角膜总高阶像差、球差、水平彗差、垂直彗差,将OSI与其进行相关分析。结果 TecnisZA9003组OSI值为2.020±0.693,MTFcutoff值为21.188±5.965,SR值为0.116±0.039;SofTecHD组OSI值为1.683±0.624,MTFcutoff值为22.797±7.205,SR值为0.131±0.032,组间比较差异均无统计学意义(P=0.053、0.350、0.131)。两组OSI与其角膜总高阶像差、球差、水平彗差、垂直彗差均没有相关性(均为P>0.05)。结论 TecnisZA9003人工晶状体和SofTecHD人工晶状体术后1个月全眼OSI没有差异,且与自身角膜像差没有相关性。 相似文献
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目的 评估LASIK术后白内障患者应用SRK-T公式、HOFFER-Q修正公式和Haigis-L修正公式进行白内障超声乳化+人工晶状体(intraocularlens,IOL)植入术后的临床效果。方法 收集从2011年1月至2015年2月行白内障超声乳化+IOL植入术且既往有LASIK术史的患者13例(21眼)。根据不同IOL计算公式分为3组,分别为SRK-T公式(6眼)、HOFFER-Q修正公式(5眼)和Haigis-L修正公式(10眼)。所有患者在白内障术前术后均进行常规检查,均由同一手术医师进行透明角膜切口超声乳化+IOL植入术。术后随访6个月,使用配对t检验比较手术前后裸眼视力、最佳矫正视力、等效球镜、眼压、角膜内皮细胞密度的变化,对不同公式计算的术后等效球镜和术后等效球镜与目标屈光度之间的差值进行方差分析。结果 术后等效球镜和术后等效球镜与目标屈光度之间的差值,在±0.25D内分别为5眼(23.81%)和1眼(4.76%),在±0.5D内均为6眼(28.57%),在±1.0D分别为10眼(47.62%)、11眼(52.38%)。与术前相比,术后6个月时裸眼视力、最佳矫正视力明显提高(均为P<0.001),等效球镜偏差度数显著减小(P<0.001)。应用SRK-T公式、HOFFER-Q修正公式和Haigis-L修正公式后,术后等效球镜误差在±1.0D内的分别为67%、80%、30%;而术后等效球镜与目标屈光度之间的差值,误差在±1.0D内的分别为50%、60%、50%。术后等效球镜和术后等效球镜与目标屈光度之间差值采用Haigis-L修正公式和HOFFER-Q修正公式组间差异有统计学意义(P<0.001、P=0.001)、Haigis-L修正公式和SRK-T公式组间差异有统计学意义(P<0.001、P<0.001)。结论 LASIK术后白内障患者在进行白内障超声乳化+IOL植入术后,HOFFER-Q修正公式计算的IOL度数误差相对较小。 相似文献
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目的 对比分析CirrusHD-OCT和A超测量中央角膜厚度的差异性及相关性,并探索CirrusHD-OCT角膜测厚与眼轴长度的关系。方法 回顾性研究2015年1月至4月拟在我院行角膜激光矫正近视手术的患者42例(84眼),按眼轴长度分为三组,A组(32眼):眼轴长度24~26mm组;B组(31眼):眼轴长度>26~28mm组;C组(21眼):眼轴长度>28mm组。利用CirrusHD-OCT和A超分别测量患者的中央角膜厚度,用配对t检验来比较两种方法测厚的差异性,用Pearson分析两种方法测厚的相关性,用两独立样本t检验比较不同眼轴组角膜厚度的差异性。结果 A组CirrusHD-OCT和A超测量患者的中央角膜厚度分别为(539.91±30.74)μm和(540.22±30.79)μm,测量结果差异无统计学意义(t=0.230,P>0.05)。B组CirrusHD-OCT和A超测量患者的中央角膜厚度分别为(543.94±31.75)μm和(544.36±33.58)μm,测量结果差异无统计学意义(t=0.304,P>0.05)。C组CirrusHD-OCT和A超测量患者的中央角膜厚度分别为(548.19±25.81)μm和(545.43±26.70)μm,测量结果差异也无统计学意义(t=1.766,P>0.05)。CirrusHD-OCT和A超测量结果具有显著正相关性(r=0.97,P<0.05)。三组间CirrusHD-OCT角膜测厚的差异性比较,A组与B组测量值差异无统计学意义(t=0.504,P>0.05)、A组与C组测量值差异无统计学意义(t=0.999,P>0.05)、B组与C组测量值差异无统计学意义(t=0.499,P>0.05)。CirrusHD-OCT测量角膜厚度与眼轴长度无相关性。结论 CirrusHD-OCT测量中央角膜厚度结果可靠,且CirrusHD-OCT和A超的测量结果显著的正相关。CirrusHD-OCT角膜测厚与眼轴长度无关。 相似文献
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Corneal biomechanical properties changes after coaxial 2.2-mm microincision and standard 3.0-mm phacoemulsification
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AIM: To compare the changes in corneal biomechanics measured by ocular response analyzer (ORA) after 2.2-mm microincision cataract surgery and 3.0-mm standard coaxial phacoemulsification.
METHODS: The prospective nonrandomized study comprised eyes with cataract that had 2.2-mm coaxial microincision or 3.0-mm standard incision phacoemulsification. The corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPcc) and Goldmann-correlated intraocular pressure (IOPg) were measured by ORA preoperatively and at 1d, 1-, 2-, 3- and 4-week postoperatively. Results were analyzed and compared between groups.
RESULTS: In both groups, CH decreased in the immediate postoperative period (P<0.05), returned to the preoperative level at one week (P=0.249) in the 2.2-mm group, and at two weeks in the 3.0-mm group (P=0.264); there was no significant change in CRF values. In 2.2-mm group, mean IOPcc and IOPg increased at 1d postoperatively (both P<0.05), and returned to preoperative level at one week (P=0.491 and P=0.923, respectively). In 3.0-mm group, mean IOPcc and IOPg increased at 1d and 1wk postoperatively (P=0.005 and P=0.029, respectively), and returned to preoperative level at 2wk (P=0.347 and P=0.887, respectively).
CONCLUSION: Significant differences between preoperative and postoperative corneal biomechanical values were found for CH, IOPcc and IOPg. But the recovery time courses were different between the two groups. The 2.2-mm coaxial microincision cataract surgery group seemed recovery faster compared to the 3.0-mm standard coaxial phacoemulsification group. 相似文献
12.
目的探讨中国青年女性生理周期期间角膜生物力学性能和眼压的节律性变化以及两者之间的关系。方法前瞻性研究。41例健康青年女性分别在月经周期初期、排卵期和月经周期末期用眼反应分析仪(ORA)对角膜补偿眼压(IOPcc)、可重复模拟Goldmman眼压(IOPg)、角膜滞后量(CH)和角膜阻力因子(CRF)进行测量。采用Pentacam对CCT进行测量。采用重复测量方差分析法分析测量参数在不同时间点的变化以及Pearson相关进行相关性分析。结果在女性生理周期的不同阶段,CCT、CH和CRF存在波动,但差异无统计学意义,在月经周期末期IOPcc和IOPg均较初期显著下降(P<0.01)。△IOPg与△CRF呈低度正相关(r=0.356,P<0.05),与△CH呈低度负相关(r=-0.336,P<0.05),△IOPcc则与△CH呈中度负相关(r=-0.702,P<0.01),与△CRF不相关(r=-0.069,P>0.05)。△CRF、△CH、△IOPg和△IOPcc均与△CCT无明显相关性(│r│均<0.3,P均>0.05)。结论在女性生理周期期间,角膜生物力学性能无明显变化但眼压在月经周期末期发生了显著下降。IOPg的变化与CH、CRF低度相关,而IOPcc则与CH中度相关,与CRF不相关。角膜生物力学性能可能是眼压的影响因素之一。 相似文献
13.
Aim: To examine corneal biomechanical properties, intraocular pressure, and central corneal thickness in uveitic eyes with Behçet disease (BD) and to compare them with healthy controls. Methods: This study included 40 eyes of 34 patients with ocular BD and 20 eyes of 20 healthy controls. Eyes with ocular BD were subdivided into active and inactive groups. Ocular response analyzer (ORA) measurements were performed on the 20 eyes of 16 patients with active BD (group 1), 20 eyes of 18 patients with inactive BD (group 2), and 20 eyes of 20 healthy volunteers who served as the control group (group 3). Corneal hysteresis (CH), corneal resistance factor (CRF), intraocular pressure (Goldmann correlated [IOPg], and corneal compensated [IOPcc]) and central corneal thickness (CCT) values were recorded. Results: Mean age of patients in groups 1, 2, and 3 was 33.81?±?9.36, 32.38?±?9.08, and 31.05?±?5.85 years, respectively (p?=?0.76). Mean CH, CRF, IOPg, IOPcc, and CCT values in groups 1, 2, and 3 were [8.51?±?1.88, 9.72?±?2.11, 19.87?±?2.92, 16.13?±?3.29, and 592.50?±?39.95], [8.46?±?1.82, 8.45?±?1.98, 15.89?±?2.68, 15.35?±?2.91, and 528.35?±?19.18], and [8.47?±?1.48, 8.43?±?1.58, 15.59?±?2.74, 15.42?±?3.19, and 526.30?±?18.21], respectively [(p1?=?0.040, 0.904, <0.001, 0.495 and <0.001 for CRF, CH, IOPg, IOPcc and CCT in group 1, respectively), (p2?=?0.989, 0.904, 0.659, 0.989, and 0.989 for CRF, CH, IOPg, IOPcc and CCT in group 2, respectively), (p3?=?0.989, 0.904, 0.660, 0.989, and 0.989 for CRF, CH, IOPg, IOPcc and CCT in group 3, respectively)]. Conclusion: CRF, IOPg, and CCT values altered in active BD group when compared with inactive BD and control group (p?0.005). Further studies are required to establish the effects of BD on corneal biomechanical properties. 相似文献
14.
Emine Sen Pinar Ozdal Melike Balikoglu-Yilmaz Pinar Nalcacioglu Yuksekkaya Ufuk Elgin Mehmet Hakan Tirhiş 《Ocular immunology and inflammation》2016,24(5):561-567
Purpose: To compare corneal biomechanics, intraocular pressure (IOP) and central corneal thickness (CCT) of 38 patients with unilateral Fuchs’ uveitis (FU) with 42 healthy controls.Methods: Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated and corneal-compensated IOP (IOPg and IOPcc, respectively) and CCT were measured.Results: The mean CH, CRF, and IOPg of the involved FU eyes were significantly lower (9.5?±?1.6, 9.0?±?1.9 and 13.1?±?4.3?mmHg) than contralateral eyes (10.1?±?1.7, 9.9?±?1.7 and 14.6?±?3.4?mmHg), and controls (10.5?±?1.5, 10.3?±?1.5 and 14.8?±?2.5?mmHg), respectively. There was no significant difference for mean IOPcc between involved FU or contralateral eyes and controls (14.8?±?4.1, 15.5?±?3.4 and 15.0?±?2.7?mmHg). The CCT values correlated with CH and CRF in the involved and contralateral eyes.Conclusions: Involved FU eyes had lower CH, CRF, and IOPg than contralateral eyes and controls, with no difference regarding IOPcc. 相似文献
15.
Internal limiting membrane dragging and peeling: a modified technique for macular holes closure surgery
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AIM: To introduce a modified technique of internal limiting membrane (ILM) centripetal dragging and peeling to treat idiopathic macular hole (IMH) and to observe the ILM-retina adhesive forces.
METHODS: Twenty-six consecutive patients with stage 3 to 4 IMH and followed up at least six months were enrolled. All patients underwent complete par plana vitrectomy, ILM dragging and peeling, fluid and gas exchange, 15% C3F8 tamponade and 2-week prone position. The best corrected visual acuity, macular hole evaluation by optical coherence tomography, and complications were evaluated.
RESULTS: The mean diameter of IMH was 524±148 μm (range: 201-683 μm), with 21 cases (80.8%) greater than 400 μm. ILM dragging and peeling were successfully performed in all cases. Most of the ILM-retina adhesive forces are severe (42.3%, 11/26), followed by mild (38.5%, 10/26), and moderate (19.2%, 5/26). The mean follow-up duration was 21.2±6.1mo. The IMH was closed in 25 (96.3%) eyes. Visual acuity (logMAR) improved significantly from 1.2±0.6 preoperatively to 0.7±0.5 postoperatively (P<0.001).
CONCLUSION: Preexisting ILM-retina adhesive force is found in IMH patients. With assistance of this force, this modified technique may help to release the IMH edges and improve the closure rate of large IMH. 相似文献
16.
目的 观察LASIK术后角膜生物力学参数和眼压测量值的变化及角膜生物力学变化与眼压的相关性。设计 前瞻性病例系列。研究对象 哈尔滨医科大学附属第一医院2014年1-12月LASIK手术患者81例(162眼)。方法 应用非接触眼压计(non-contact tonometer,NCT)分别在术前及术后3个月测量眼压。同时应用眼反应分析仪(ocular response analyzer,ORA)测量角膜滞后量(corneal hysteresis,CH)、角膜阻力因子(corneal resistance factor, CRF)、模拟Goldmann 眼压(Goldmann intraocular pressure,IOPg)和角膜补偿眼压(corneal-compensated intraocular pressure,IOPcc)。比较手术前后各参数的变化并分析术后角膜生物力学参数变化与眼压测量值的相关性。 主要指标 手术前后NCT、IOPcc、IOPg、CH、CRF。 结果 LASIK术后3个月CH、CRF、IOPcc、IOPg、NCT测量值与术前比较均显著降低,术后IOPcc与IOPg和NCT之间比较差异均有统计学意义(P<0.05);△CH、△CRF与△IOPcc、△IOPcc- IOPg和△IOPcc-△NCT均成负相关,△CH、△CRF与△IOPg和△NCT均成正相关(P<0.05);CH和CRF的减少量与眼压测量值下降具有相关性(P<0.05)。结论 LASIK术后角膜生物力学参数和眼压测量值均较术前显著降低,眼压测量值下降与CH和CRF的减少量具有相关性,说明眼压下降的程度可能受角膜生物力学特性的影响。 相似文献
17.
目的 探讨同轴微切口超声乳化白内障吸出术对角膜内皮细胞的损伤及其修复特点。方法 选取2011年1月至2013年12月我院收治的100例(100眼)年龄相关性白内障患者为研究对象,根据手术方式不同分为常规切口组和微切口组,分别行常规3.0mm切口白内障超声乳化术和1.8mm同轴微切口超声乳化白内障手术,使用角膜内皮显微镜于术前、术后1d、1周、1个月、3个月检查角膜内皮细胞密度和形态,对两组结果进行观察比较。结果 两组术前角膜内皮细胞密度组间比较差异无统计学意义(P>0.05);两组术后不同时间角膜内皮细胞密度均低于术前,差异均有统计学意义(均为P<0.05);两组术后不同时间点组间比较,差异均无统计学意义(均为P>0.05)。两组术前六角形细胞比例组间比较,差异无统计学意义(P>0.05);两组术后不同时间六角形细胞比例均低于术前,差异均有统计学意义(均为P<0.05);两组术后不同时间点组间比较,差异均无统计学意义(均为P>0.05)。两组术前角膜内皮细胞变异系数组间比较,差异无统计学意义(P>0.05);两组术后不同时间角膜内皮细胞变异系数均高于术前,差异均有统计学意义(均为P<0.05);两组术后不同时间点组间比较,差异均无统计学意义(均为P>0.05)。两组术后1d、1周中央角膜厚度增加明显,均高于术前,差异均有统计学意义(均为P<0.05),术后1个月、3个月逐渐恢复至术前水平,与术后1d、1周比较,差异均有统计学意义(均为P<0.05);两组术前及术后不同时间点中央角膜厚度组间比较差异均无统计学意义(均为P>0.05)。结论 同轴微切口白内障超声乳化手术进一步缩小了手术切口,术后恢复更快,是一种安全有效的手术方式。 相似文献
18.
Effect of biometric characteristics on biomechanical properties of the cornea in cataract patient
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Xue-Fei Song Achim Langenbucher Zisis Gatzioufas Berthold Seitz Moatasem El-Husseiny 《国际眼科》2016,9(6):854-857
AIM: To determine the impact of biometric characteristics on the biomechanical properties of the human cornea using the ocular response analyzer (ORA) and standard comprehensive ophthalmic examinations before and after standard phacoemulsification.
METHODS: This study comprised 54 eyes with cataract with significant lens opacification in stages I or II that underwent phacoemulsification (2.8 mm incision). Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc) were measured by ORA preoperatively and at 1mo postoperatively. Biometric characteristics were derived from corneal topography [TMS-5, anterior equivalent (EQTMS) and cylindric (CYLTMS) power], corneal tomography [Casia, anterior and posterior equivalent (EQaCASIC, EQpCASIA) and cylindric (CYLaCASIA, CYLpCASIA) power], keratometry [IOLMaster, anterior equivalent (EQIOL) and cylindric (CYLIOL) power] and autorefractor [anterior equivalent (EQAR)]. Results from ORA were analyzed and correlated with those from all other examinations taken at the same time point.
RESULTS: Preoperatively, CH correlated with EQpCASIA and CYLpCASIA only (P=0.001, P=0.002). Postoperatively, IOPg and IOPcc correlated with all equivalent powers (EQTMS, EQIOL, EQAR, EQaCASIA and EQpCASIA) (P=0.001, P=0.007, P=0.001, P=0.015, P=0.03 for IOPg and P<0.001, P=0.003, P<0.001, P=0.009, P=0.014 for IOPcc). CH correlated postoperatively with EQaCASIA and EQpCASIC only (P=0.021, P=0.022).
CONCLUSION: Biometric characteristics may significantly affect biomechanical properties of the cornea in terms of CH, IOPcc and IOPg before, but even more after cataract surgery. 相似文献
19.
Changes in corneal biomechanics and intraocular pressure following Femto-LASIK using Goldman applanation tonometry and ocular response analyzer
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Ahmed Yassin Hemi Omar M Sai Asser A.E. Abdel-Megui Mohammed Iqbal Amani E Badawi 《国际眼科》2020,13(5):782-787
AIM:To compare intraocular pressure(IOP)measurements before and after laser in situ keratomileusis(LASIK)with a femtosecond laser for flap creation using ocular response analyzer(ORA)and Goldmann applanation tonometry,and to identify factors that may influence the preoperative and postoperative IOP.METHODS:A prospective study conducted on myopic patients who underwent LASIK using a femtosecond laser for flap fashioning.Enrolled patients were evaluated preoperatively,6 wk and 3 mo postoperatively for manifest refraction(MR),keratometric(K)readings and central corneal thickness(CCT)using a scheimpflug-based topography.Corneal resistance factor(CRF),corneal hysteresis(CH),Goldmann correlated IOP(IOPg)and corneal compensated IOP(IOPcc)were measured using ORA besides IOP assessment by Goldman applanation tonometry(GAT).RESULTS:There was a statistically significant decrease in measures of IOPg by 3.35±0.83 mm Hg,followed by GAT which decreased by 2.2±0.44 mm Hg,and the least affected by operation was IOPcc which decreased only by 0.87±0.1 mm Hg after 6 wk.After 3 mo follow up there was a statistically significant decrease in IOPcc which decreased only by 0.76±0.4 mm Hg,followed by IOP GAT by 1.6±0.5 mm Hg,and the most affected by operation was IOPg which decreased by 2.3±0.3 mm Hg.Correspondingly,there was a statistically significant decrease in CH and CRF after 6 wk and 3 mo.At 3 mo,the preoperative MR and preoperative GAT were prominent significant predictors of the postoperative GAT changes.The prediction equation was subsumed.CONCLUSION:IOP measurements and corneal biomechanical factors reduce significantly after LASIK with a femtosecond laser for flap creation.The IOPcc values are less influenced by changes in corneal properties than IOPg and GAT,indicating that IOPcc may provide the most reliable measurement of IOP after this procedure. 相似文献
20.
目的 比较同轴微小切口与标准切口超声乳化吸出术在原发性闭角型青光眼(primaryangleclosureglaucoma,PACG)滤过术后白内障摘出术中的安全性与有效性。方法 连续收集抗PACG滤过术后白内障患者72例(90眼),随机分为两组:试验组37例(49眼)行2.0mm同轴微小切口超声乳化术,对照组35例(41眼)行3.0mm标准透明角膜切口超声乳化术,观察两组术中有效超声乳化时间、超声能量及术中前房稳定性,于术后1d、7d观察角膜水肿、视力情况,同时于术前、术后7d观察两组患者角膜内皮细胞计数、角膜散光。结果 试验组和对照组患者术中超声乳化时间分别为(6.43±1.03)s、(6.54±1.25)s,超声能量分别为(16.52±2.35)%、(15.94±3.53)%,两组间超声乳化时间和超声能量比较,差异均无统计学意义(均为P>005)。两组术后角膜水肿均以1级为主,术后1d、7d两组角膜水肿程度比较,差异均有统计学意义(均为P<0.05)。术后1d、7d试验组最佳矫正视力均好于对照组,差异均有统计学意义(均为P<0.05)。试验组术前角膜散光为(0.52±0.28)D,术后7d为(0.56±0.32)D,差异无统计学意义(P>0.05);对照组术前角膜散光为(0.49±0.31)D,术后7d为(0.72±0.43)D,差异有统计学意义(P<0.05);两组术后7d角膜散光比较,差异有统计学意义(P<0.05)。两组术后7d角膜内皮细胞计数均低于术前(均为P<0.01);术后7d试验组角膜内皮细胞计数高于对照组,差异有显著统计学意义(P<0.01)。结论 同轴微小切口超声乳化术具有术中前房稳定性好,术后角膜内皮细胞丢失率低,促进视力迅速恢复,安全可靠等优点。 相似文献