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1.
Background Anastomotic leaks after bariatric surgery carry high morbidity and mortality. We aimed to describe our experience of the diagnosis
and management of gastrointestinal anastomotic leaks in patients undergoing laparoscopic gastric bypass in a single institution.
Methods Of 1,200 patients who underwent laparoscopic Roux-en-Y gastric bypass with manual gastrojejunal anastomosis for morbid obesity
from January 2002 to January 2007, we retrospectively analyzed 59 patients with anastomotic leak. The location of the leak,
day of diagnosis, diagnostic methods, clinical manifestations, treatment modalities, associated complications, and length
of hospital stay were analyzed.
Results Leaks were located as follows: 67.8% in the gastrojejunostomy, 10.2% in the gastric pouch, 3.4% in the excluded stomach, 5.1%
in the jejunojejunal anastomosis, 3.4% in the gastrojejunostomy plus pouch, 3.4% in the pouch plus excluded stomach, and 6.8%
in undetermined sites. Routine upper gastrointestinal series revealed contrast extravasation in nine patients (15.3%). Leaks
were asymptomatic at diagnosis in 29 patients (49.2%). Surgical reintervention was carried out in 23 patients, and conservative
treatment was provided in the remaining 36. Transfer to the intensive care unit was required in 11 patients, with five deaths
(0.4%).
Conclusion In our experience, most anastomotic leaks can be managed with conservative measures alone. In many patients, abdominal drains
are effective in the management of leaks, obviating the need for reintervention. Nasoenteral nutrition was effective in the
non-operative management of gastrojejunal leaks in patients without signs of systemic toxicity. 相似文献
2.
BACKGROUND: Laparoscopic Roux-en-Y gastric bypass (LRYGB) involves a combination of both restrictive and mal-absorptive mechanisms and has become the procedure of choice for patients with morbid obesity in Western countries. However, its efficacy remains uncertain in Asian populations. We report our pilot experience with LRYGB in a Chinese population. METHODS: Between August 2005 and February 2007, 100 morbidly obese patients received LRYGB. We evaluated the learning curve for the operation, its efficacy in weight reduction, and its postoperative complications. RESULTS: Surgical time reached a plateau after about 50 cases, decreasing from 216 min for the initial 50 patients to 105 min for the final 50. The conversion rate from laparoscopic to open surgery was 2%. The mean percent body mass index loss was 33.9% after 12 months. Twenty-four complications occurred in 18 patients, but most resolved with conservative treatment without mortality. Patients with advanced age (P = 0.04) or hypertension (P = 0.03) were at increased risk for complications leading to prolonged surgical times and hospital stays. The complication rate declined as technical expertise increased. CONCLUSION: In Chinese patients with morbid obesity, LRYGB is promising procedure because of its acceptable learning curve, good efficacy, and low complication rate. 相似文献
3.
Background Internal hernias have been described after laparoscopic Roux-en-Y gastric bypass (LRYGB) as a major problem. Thus, many routinely
close defects during LRYGB. In our technique, we do not close any defects. We hypothesize that not closing the defects would
not cause a significant internal hernia rate diagnosed during reoperations.
Methods Patients who were reoperated after LRYGB were included in this study. Only patients who had a laparoscopic or open exploration
focused on inspecting for internal hernias are reported here. The LRYGB technique that was utilized included an antecolic,
antegastric gastrojejunostomy, minimal division of the small bowel mesentery, a long jejunojejunostomy performed with three
staple lines, adequate division of the omentum, and placement of the jejunojejunostomy above the colon in the left upper quadrant.
Results There were a total of 387 patients who had LRYGB from 2002 to 2007 utilizing this particular technique. Fifty-four patients
had a reoperation at an average of 24 (Range: 1–60) months postoperatively. The procedures were abdominoplasty, cholecystectomy,
diagnostic laparoscopy, and lysis of adhesions. While two patients had a defect present, no patient had an internal hernia
despite aggressive attempts to diagnose one.
Conclusions Internals hernias are not common after our particular method of LRYGB. Before adopting and advocating routine closure, surgeons
should consider the surgical technique and the true associated incidence of internal hernias. We do not recommend routine
closure of these defects with our technique.
Presented in part at International Federation for the Surgery of Obesity annual meeting; August 2006; Sydney, Australia. 相似文献
4.
The technique of gastric bypass has undergone an evolution over the last 20 years, although it is often individualized based
on surgeon preference. Whereas many surgeons divide and separate the gastric pouch from the distal bypassed stomach, some
surgeons choose to staple, but not cut and separate the pouch. Staple-line failure resulting in a gastrogastric fistula and
weight regain is a worrisome complication. We discuss a case of a patient with an obvious staple-line failure, which resulted
in complete weight regain. She underwent laparoscopic repair and was discharged on postoperative day 1. Laparoscopic repair
of a staple-line disruption after an open uncut gastric bypass is feasible.
Presented at the World Congress of the International Federation for the Surgery of Obesity, Sydney, Australia, August 31,
2006. 相似文献
5.
BACKGROUND: Open Roux-en-Y gastric bypass (RYGB) is the gold standard for obesity surgery in this country. The introduction of a totally laparoscopic technique in 1994 has increased the demand for obesity surgery and for this particular approach. Several studies show comparable results and complications between the open and laparoscopic procedure. However, the continued study of surgical technique, analysis of results, and, in particular, the education of the surgical resident in this approach must be accomplished. METHODS: A retrospective analysis was performed of 204 patients undergoing attempted laparoscopic RYGB, with surgical resident involvement, from March of 2000 to April of 2002. Surgical candidates had a body mass index (BMI) greater than 40 with a history of failed diets. All procedures were performed by a single board-certified general surgeon (P.F.R.) at a tertiary-care, teaching, community hospital with surgical residents assisting. Age, sex, ideal body weight, preoperative BMI and weight, surgical time, length of stay, complications, and resident level and role were recorded. Surgical technique was refined during the study period. RESULTS: A total of 204 patients underwent attempted laparoscopic RYGB with 4 (2%) being converted to open procedures and 1 mortality. Surgical time averaged 182 minutes. The average length of stay was 1.8 days. Four patients (2%) developed postoperative anastomotic leaks. Three patients (1.5%) developed internal hernias requiring reoperation. Four patients (2%) developed postoperative hemorrhage. One patient (0.5%) had a pulmonary embolism. Surgical residents were involved in all procedures and gradually expanded their role as skill increased. CONCLUSIONS: Laparoscopic RYGB can be performed safely in a community setting with surgical residents as either assistant or surgeon, further preparing them to perform this and other advanced laparoscopic procedures after completion of their training. 相似文献
6.
O. N. Tucker S. Szomstein R. J. Rosenthal 《Journal of gastrointestinal surgery》2007,11(12):1673-1679
Background Gastro–gastric fistula (GGF) formation is uncommon after divided laparoscopic Roux-en-Y gastric bypass (LRYGB) for morbid
obesity. Optimal surgical management remains controversial.
Methods A retrospective review was performed of a prospectively maintained database of patients undergoing LRYGB from January 2001
to October 2006.
Results Of 1,763 primary procedures, 27 patients (1.5%) developed a GGF and 10 (37%) resolved with medical management, whereas 17
(63%) required surgical intervention. An additional seven patients requiring surgical intervention for GGF after RYGB were
referred from another institution. Indications for surgery included weight regain, recurrent, or non-healing gastrojejunal
anastomotic (GJA) ulceration with persistent abdominal pain and/or hemorrhage, and/or recurrent GJA stricture. Remnant gastrectomy
with GGF excision or exclusion was performed in 23 patients (96%) with an average in-hospital stay of 7.5 days (range, 3–27).
Morbidity in six patients (25%) was caused by pneumonia, n = 2; wound infection, n = 2; staple-line bleed, n = 1; and subcapsular splenic hematoma, n = 1. There were no mortalities. Complete resolution of symptoms and associated ulceration was seen in the majority of patients.
Conclusion Although uncommon, GGF formation can complicate divided LRYGB. Laparoscopic remnant gastrectomy with fistula excision or exclusion
can be used to effectively manage symptomatic patients who fail to respond to conservative measures.
This paper was presented at the SSAT Poster Presentation session on May 21st 2007 at the SSAT Annual Meeting at Digestive
Disease Week, Washington (poster ID M1590). 相似文献
7.
Background Since 1994, laparoscopic Roux-en-Y gastric bypass (LRYGBP) has gained popularity for the treatment of morbid obesity. In analogy
to open surgery, the operation was initially performed in a retrocolic fashion. Later, an antecolic procedure was introduced.
According to short-term studies, the antecolic technique is favorable. In this study, we compared the retrocolic vs the antecolic
technique with 3 years of follow-up. We hypothesized that the antecolic technique is superior to the retrocolic in terms of
operation time and morbidity.
Methods 33 consecutive patients with retrocolic technique and 33 patients with antecolic technique of LRYGBP were compared, using
a matched-pair analysis. Data were extracted from a prospectively collected database. The matching criteria were: BMI, age,
gender and type of bypass (proximal or distal). The end-points of the study were: operation time, length of hospital stay,
incidence of early and late complications, reoperation rates and weight loss in the followup over 36 months.
Results In the retrocolic group, operation time was 219 min compared to 188 min in the antecolic group (P = 0.036). In the retrocolic
group, 3 patients (9.1%) developed an internal hernia and 4 patients (12.1%) suffered from anastomotic strictures. In the
antecolic group, 2 patients (6.1%) developed internal hernias and in 3 patients (9.1%) anastomotic strictures occurred. Median
hospital stay in the retrocolic group was 8 days compared to 7 days in the antecolic group. In the antecolic group, the mean
BMI dropped from 46 kg/m2 to 32 kg/m2 postoperatively after 36 months. This corresponds to an excess BMI loss of 66%. In the
retrocolic group, we found a similar decrease in BMI from preoperative 45 kg/m2 to 34 kg/m2 after 36 months (P = 0.276).
Conclusion The results of our study demonstrate a reduction of operation time and hospital stay in the antecolic group compared to the
retrocolic group. No differences between the two groups were found regarding morbidity and weight loss. Taken together, the
antecolic seems to be superior to the retrocolic technique. 相似文献
8.
Background It is well known that obesity is accompanied by changes in thyroid function. Hypothyroidism is associated with increased body
weight. The aim of this study was to evaluate the operative outcomes, weight loss, and the effect of weight loss on thyroid
function in morbidly obese patients with hypothyroidism who undergo laparoscopic Roux-en-Y gastric bypass (LRYGB) surgery.
Methods A retrospective review of 20 morbidly obese female patients with hypothyroidism and on thyroid replacement therapy who underwent
LRYGB between January 2003 and August 2006.
Results Mean preoperative body mass index (BMI) was 47.6 kg/m2 (range 38–58.5 kg/m2). Average patient age was 44.5 years (range 21–66 years). There was one early complication (pneumonia). Late complications
included one death, three anastomotic strictures, and one small bowel obstruction. The patients were followed for a mean of
13.5 months (range 3–24 months). Their mean excess body weight loss was 13 kg (22%), 24.4 kg (39.4%), 33.2 kg (63.3%), 38.4 kg
(65%), 41.7 kg (70%), and 43 kg (73%) at 1, 3, 6, 9, 12, and 24 months, respectively. Change in a mean BMI was the same regardless
of the patient preoperative and postoperative thyroxine dose. Hypothyroidism resolved in 5(25%) patients, improved in 2(10%)
patients, unchanged in 8(40%) patients, and worsened in 5 (25%) patients. Most of the five whose hypothyroidism worsened had
thyroid autoimmune disease.
Conclusions Hypothyroidism appears to improve in the vast majority of morbidly obese patients who undergo LRYGB, except for those whose
thyroid disease is autoimmune in nature. 相似文献
9.
Melissa Beitner Yuying Luo Marina Kurian 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2015,19(1)
Methods:A retrospective review of all procedures performed by a fellowship-trained surgeon (MK) from December 1, 2000, to October 31, 2013, identified patients who underwent LRYGB. We evaluated perioperative outcomes in 1117 patients and examined the impact of modification of surgical techniques on complications. The patients were divided into 4 groups: cases 1–100 (group 1), cases 101–400 (group 2), cases 401–700 (group 3), and cases 701-1117 (group 4).Results:Operating time decreased significantly after the initial 100 cases, from 179.1 minutes for group 1 to 122.1 minutes for group 4. With experience, early complication rates improved from 25.0% to 5.0%, but the rates of early reoperation increased from 1.0% to 2.2% over the 4 case groups. Late complication and reoperation rates increased from 4.0% to 10.5%. However, rates of bleeding, early stricture, internal hernia, and wound infection all decreased after the modification of surgical techniques.Conclusions:Operating time and early complication rates decreased with operative experience, but late complication and early and late reoperation rates increased. However, after modifications of surgical technique, common complications of LRYGB decreased to rates lower than those reported in several gastric bypass case series in the literature. The findings in this study will be helpful to fellow bariatric surgeons who are refining their strategies for reducing morbidity related to LRGYB. 相似文献
10.
Background Co-morbidities and the metabolic response to intervention in morbid obesity have been reported to vary among different ethnic
groups. We compared the rate of weight loss, effectiveness of gastric bypass surgery, and variables influencing success after
gastric bypass in Hispanics compared to Caucasians.
Methods Morbidly obese adult (>18 years old) patients (body mass index [BMI] 40 or above) evaluated by our bariatric group from 2005
to 2006 who underwent Roux-en-Y gastric bypass (RYGBP) were studied. Every patient was evaluated for height, weight, BMI,
percent body fat, fat mass, serum metabolic analysis (SMA) 12, lipid profile, complete blood count (CBC), iron, ferritin,
Vitamins A, D, and B1, complete urinalysis and Fibrospect score II. Weight loss was evaluated at 1, 3, 6, and 12 months.
Results Seventy-five patients underwent successful open RYGBP with no mortality. Regardless of the significant difference in age and
co-morbidities, the mean percentage of total weight loss after 1 year of follow-up was 32% for Hispanics and 30% for Caucasians
with no significant difference (p > .5). When comparing the percentage of excess weight lost (% EWL) at 1, 3, 6, and 12 months, there was no significant difference
between both groups. Using multiple regression analysis, we found that high-density lipoprotein (HDL) and systolic blood pressure
(SBP) significantly predicted EWL at 12 months in Caucasians and Fibrospect predicted significantly EWL at 1 year.
Conclusion At 1 year after RYGBP, both ethnic groups lost ∼77–80% of their EWL and BMI. All Caucasians and 95.7% of Hispanics achieved
successful weight loss (>50% EWL). 相似文献
11.
Background: Intra-operative pneumothorax (PTX) is an infrequent complication of laparoscopic surgery. Most cases are attributed
to CO2 diffusion across congenital diaphragmatic defects and resolve spontaneously. We report a case of PTX during a laparoscopic
Roux-en-Y gastric bypass (LRYGBP). When applied to this specific patient population, the current literature recommendations
for the management of intra-operative PTX are questioned. Material and Methods: A retrospective chart review of 400 consecutive
LRYGBP procedures performed over a 30-month period revealed 1 case of PTX (0.025%). Results: A bulging left diaphragm, hypotension,
bradycardia, decreased pO2, and elevated EtCO2 and airway pressures, were noted early in the case. She initially responded to conservative management but required multiple
subsequent hospital admissions for pulmonary complications. Conclusions: Pneumoperitoneum-induced PTX during laparoscopic
bariatric surgery is a rare complication. Its treatment must be based on the potential underlying cause, with consideration
of these patients' often delicate pulmonary status. In stable patients, where the PTX is attributed to diaphragmatic or hiatal
dissection, expectant treatment is appropriate. In all other situations, however, we believe that tube thoracostomy is indicated.
An algorithm for treatment of PTX in laparoscopic bariatric surgery is proposed. It follows the dictum of maintaining extreme
vigilance and a low threshold for aggressive intervention in this group of patients. 相似文献
12.
Background Literature regarding the effect of Roux-en-Y gastric bypass (RYGBP) on vitamin D level shows contradictory findings. Our goal
was to determine preoperatively vitamin D levels, to evaluate the efficacy of therapeutic and prophylactic doses of vitamin
D and to assess the relationship of 25-OH vitamin D level and body mass index (BMI).
Methods We conducted a retrospective cross-sectional study of 72 patients who underwent RYGBP from April 2007 to October 2007 in Bariatric
Surgery Department at Saint Vincent Charity Hospital.
Results Our study demonstrated that 80% of the obese patients undergoing RYGBP had serum 25-OH vitamin D levels of less than 32 ng/ml.
Postoperative data show that 45% of these patients continue being vitamin D insufficient despite the treatment. We demonstrated
that a statistically significant inverse correlation between BMI and 25-OH vitamin D levels (r = 0.464, p = 0.01) exists.
Conclusion Our finding strongly supports the need for aggressive monitoring of vitamin D levels for long-term prevention of complications
of vitamin D deficiency in gastric bypass patients. Identifying the factors that predict patient’s responses to vitamin D
supplementation requires larger-scale studies and further analysis of these tendencies suggested by our findings. 相似文献
13.
14.
Pajecki D Dalcanalle L Souza de Oliveira CP Zilberstein B Halpern A Garrido AB Cecconello I 《Obesity surgery》2007,17(5):601-607
Background Short-term results (24 to 36 months) after Roux-en-Y gastric bypass (RYGBP) have been extensively described. Little is reported
on the patients operated ≥ 5 years ago. We analyzed the results of weight loss, resolution of co-morbidities and nutritional
complications of patients submitted to the silicone ring RYGBP, at least 5 years before.
Methods 75 morbidly obese patients who underwent silicone ring RYGBP between Oct 1995 and Dec 1999, 18 men and 57 women, were studied.
Demographic data, nutritional status and the presence of co-morbidities (type 2 diabetes, hypertension, sleep apnea, dyslipidemia)
were accessed. Pre- and postoperative BMI were registered, along with excess weight loss (EWL). Nutritional deficiencies were
accessed by laboratory assays.
Results Mean follow-up was 87 months. Initial BMI was 56.7 ± 10 kg/m2. After 2 years, BMI had dropped to 29.3 ± 6.8, and by the last interview BMI was 35.5 ± 10. %EWL after 2 years was 80.2 ± 17.3%,
and at the end was 71.8 ± 21.6%. After 2 years, only 1 of the 75 patients (1.33%) had not achieved an EWL of at least 50%.
At the end, 23 patients (30.6%) could not maintain this EWL. Resolution of diabetes was 76.5%, arterial hypertension 37.3%
and sleep apnea 93.5%. Iron, vitamin B12 and vitamin D were the most common nutritional deficiencies.
Conclusions Long-term follow-up (5 to 9 years) after the RYGBP was associated with satisfactory mantainance of EWL, and resolution or
improvement of the main co-morbidities was observed in the majority of the patients. 相似文献
15.
Agaba EA Shamseddeen H Gentles CV Sasthakonar V Gellman L Gadaleta D 《Obesity surgery》2008,18(11):1359-1363
Methods We performed a retrospective analysis of 1,364 consecutive morbidly obese patients who underwent restrictive–malabsorptive
Roux-en-Y gastric bypass (RYGBP) between January 1998 and December 2004. A selective use of open and laparoscopic approaches
was employed since 2001. Patients were seen in the office at 1 week; 2, 3, 6, 9, 12, and 24 months; and yearly thereafter.
During visits, each patient was weighed and dietary intake and exercise regimen were recorded.
Results We report a sustained weight reduction in over 90% of patients. The anastomotic leak rate was 0.15%, the 30-day readmission
rate was 1.17%, and the overall mortality rate was 0.15%. Minor surgical site infection rate was 0.5%, and revision to long
limb RYGBP rate was 0.07%.
Conclusions Morbid obesity represents a significant health issue. None of the medical methods of weight reduction provide a lasting weight
reduction. Surgery offers the only achievable long-term solution. Although not yet universally employed, laparoscopic RYGBP
is rapidly becoming the standard operation for the surgical treatment of clinically severe obesity. 相似文献
16.
Background The concern about internal hernias has prompted recommendations for routine closure of defects during laparoscopic Roux-en-Y
gastric bypass (LRYGBP). Our belief is that not all techniques require closure of defects. We hypothesize that nonclosure
of defects with our particular technique would not cause a significant clinically evident internal hernia rate.
Methods All patients who were operated on between December 2002 and June 2005 were included in this study. The technique that was
utilized included an antecolic antegastric gastrojejunostomy (GJ), division of the greater omentum, a long jejunojejunostomy
(JJ) performed with three staple-lines, a short (<4 cm) division of the small bowel mesentery, and placement of the JJ above
the colon in the left upper quadrant. Clinical records were reviewed for reoperations.
Results here was a total of 300 patients, and no incidence of internal hernia. In the first 100 patients, there was 97% follow-up
for 1 year or more. Four patients underwent reoperations for unexplained abdominal pain. Intraoperative findings included
an adhesive band from the JJ to the colon (1), an adhesive band from the JJ to the anterior abdominal wall (1), an adhesive
band 3 cm from the GJ to the anterior abdominal wall (1), and adhesions of the jejunum to the anterior abdominal wall (1).
No patient had an internal hernia.
Conclusions Internal hernias are not common after this particular method of LRYGBP. Before adopting routine closure of potential spaces,
surgeons should consider their technique, follow-up, and incidence of internal hernias. Routine closure of these defects is
not always necessary. 相似文献
17.
18.
Background The purpose of this study was to compare obstetric and neonatal outcomes after Roux-en-Y gastric bypass (RYGB) to those in
women without such surgery.
Methods Women with RYGB (cases) were matched for maternal age and prior cesarean to the next two consecutive women delivering without
prior bariatric surgery (controls). Pregnancy and newborn outcomes were compared by univariate analysis. Outcomes approaching
or reaching statistical significance were evaluated by conditional logistic regression controlling for maternal body mass
index (BMI).
Results Despite gastric bypass, the 38 cases were heavier (BMI 33.4 ± 7.3 vs. 28.1 ± 6.7 kg/m2, p < 0.001) and more often obese (BMI ≥ 30 kg/m2, 26/38 (68.4%) vs. 20/76 (26.3%), p < 0.001) than controls. Variables evaluated by logistic regression adjusted for BMI did not differ in cases versus controls,
including hypertension (odds ratio [OR] 2.62, 95% confidence interval [CI] 0.66–10.50), preterm premature rupture of membranes
(OR 0.24, 95% CI 0.02–3.38), oligohydramnios (OR 2.39, 95% CI 0.66–8.61), and delivery ≥41 weeks (OR 0.57, 95% CI 0.11–2.97).
Discussion Obstetric and neonatal outcomes after RYGB are similar to those of our general obstetric population.
Reprints unavailable. 相似文献
19.
Background The prevalence of gastroesophageal reflux disease (GERD) is increasing in Eastern and Western countries. Obesity is recognized
as a risk factor of gastroesophageal reflux disease. However, little information is available on the prevalence of gastroesophageal
reflux disease in morbidly obese Chinese patients. The aim of this study was to compare the prevalence of GERD in Chinese
patients with morbid obesity and age- and sex-matched controls, and we also assessed the effect of Roux-en-Y gastric bypass
on reflux symptoms and erosive esophagitis.
Methods Between November 2006 and February 2008, 150 morbidly obese Chinese patients underwent laparoscopic Roux-en-Y gastric bypass.
Gastroesophageal reflux disease questionnaires and esophagogastroduodenoscopy results were assessed in all cases before surgery.
The prevalence of reflux symptoms and erosive esophagitis was compared with the prevalence in a database of 300 age- and sex-matched
controls. We also compared baseline and postoperative characteristics at 12 months after operation.
Results Patients with morbid obesity had higher frequencies of reflux symptoms (16% vs. 8%, P = 0.01) and erosive esophagitis (34% vs. 17%, P < 0.01) than those of controls. Twelve months after laparoscopic Roux-en-Y gastric bypass, 26 patients received follow-up
evaluations. In addition to substantial weight loss, the prevalence of reflux symptoms and erosive esophagitis decreased significantly
after operation (19.2% vs. 0%, P = 0.05, and 42.3% vs. 3.8%, P < 0.01, respectively).
Conclusions Gastroesophageal reflux disease is pervasive in Chinese patients with morbid obesity and Roux-en-Y gastric bypass substantially
improves not only the reflux symptoms but also the erosive esophagitis. 相似文献
20.
A case is reported of a patient after long-limb Roux-en-Y gastric bypass who presented with a volvulus of the Roux limb. This is the first report of this complication in the literature. 相似文献