The fate of patients with intermittent claudication-comparison of surgical and non-surgical treatment]

The purpose of this study was to determine the operative indication for patients with intermittent claudication because of arteriosclerosis obliterans, and to compare the late result of the surgical treatment group (182 cases, 250 limbs) with that of the non-surgical treatment group (35 cases, 43 limbs). There were 3 operative deaths and 34 late deaths in the surgical group, and 14 late deaths in the non-surgical group. The number one cause of death was heart failure, including ischemic heart disease, in both groups. The 4-year cumulative patency rates were 91% in the aorto-iliac, 71% in the femoro-distal and 79% in the aorto-femoro-distal arterial reconstructions. Long term symptom free rates of the surgical group and the non-surgical group, except fatal case, were 83% and 44% in the aorto-iliac, 79% and 27% in the femoro-distal, 87% and 33% in the aorto-femoro-distal arterial regions, respectively. Late result of intermittent claudication in the surgical group was better than that in the non-surgical group. We concluded that intermittent claudication should be considered to be the indication for surgery, except for the cases with high risk diseases or malignant diseases.     

The fate of patients with intermittent claudication managed nonoperatively

Of 100 patients with intermittent claudication, followed an average of six years, a surprising 78 per cent either showed improvement or remained stable regarding the presenting complaint. However, 39 per cent showed evidence of further progression of atherosclerosis. In patients with femoropopliteal occlusion in one leg, almost 40 per cent had occlusion in the other leg after two to six years. The amputation rate was 7 per cent but six of these seven patients had severe diabetes. This study suggests that we are not causing limb loss by adhering to stringent criteria for bypass grafting. It also suggests that the patient with intermittent claudication without associated grave signs has a better than 50 per cent chance of improving and a better than 60 per cent chance that his disease will not show evidence of significant progression during a five to six year period. Such data should be taken into consideration when patients are considered for arterial reconstruction.     

创伤性重症急性胰腺炎早期手术与非手术治疗时机选择的临床研究

目的 探讨创伤性重症急性胰腺炎患者的手术治疗与非手术治疗疗效.方法 回顾分析36例创伤性重症急性胰腺炎患者的临床资料.结果 36例创伤性重症急性胰腺炎患者手术组21例,死亡2例,病死率为9.52%,非手术组15例,死亡5例,病死率为33.33%,非手术组病死率高于手术组,有统计学差异(P＜0.05).结论 对必须手术治疗的创伤性重症急性胰腺炎,及时手术就能够明显提高创伤性重症急性胰腺炎的治愈率.     

Effect of surgical treatment on physical activity and bone resorption in patients with neurogenic intermittent claudication

The effect of surgical treatment on physical activity and bone resorption was examined in patients with neurogenic intermittent claudication. Nineteen patients, 50–77 years of age, with neurogenic intermittent claudication (mean, 162 m; range, 20–400 m) caused by degenerative lumbar disease were included in the study. Decompressive laminectomy alone was performed for 7 patients with lumbar spinal stenosis (LSS) and 5 patients with degenerative lumbar spondylolisthesis (DLSL), and decompressive laminectomy, with a Graf stabilization system, was performed for 7 patients with DLSL associated with flexion instability. Clinical symptoms and levels of urinary cross-linked N-telopeptides of type I collagen (NTx) were assessed before and 12 months after surgery. Subjective symptoms, including low back pain, leg pain and/or tingling, and gait disturbance, as well as restriction of activities of daily living were significantly alleviated by the surgical treatment, resulting in an increase in physical activity. Urinary NTx levels were significantly decreased by the surgical treatment, from 63.1 ± 16.9 (mean ± SD) nmol BCE/mmol Cr to 52.1 ± 11.2 nmol BCE/mmol Cr (P < 0.05). These findings suggest that surgical treatment appears to alleviate the clinical symptoms and increase physical activity in patients with LSS or DLSL, potentially resulting in the suppression of bone resorption. Surgical treatment may contribute to the prevention of physical inactivity-induced osteoporosis in elderly patients with neurogenic intermittent claudication caused by degenerative lumbar disease. Received: June 22, 2001 / Accepted: September 17, 2001     

Results of surgical versus non-surgical treatment of Achilles tendon rupture

Between 1990 and 2001, 292 patients with acute Achilles tendon rupture were admitted to our institution. Depending on the day of admission patients were allocated either to the Department of Trauma Surgery or to the Department of Orthopaedics. Two hundred and twelve patients (mean age 37±9.4 years) were treated with surgical suture followed by plaster for 6 weeks. Eighty patients were treated non-surgically with splinting for 12 weeks. For both groups mean follow-up was 6±3 years. There were 14 re-ruptures, ten after surgical repair and four after non-surgical treatment. In the surgical group there were seven major wound problems, 11 minor wound complications and six patients with complaints from the sural nerve. In the non-surgical group one patient suffered a pulmonary embolism after a re-rupture, 3 months after the initial rupture. There was no difference in mean ankle score and patient-satisfaction score between groups. Only 52% regained their original sports activity level, slightly better in the surgically treated group. With a non-significant difference in re-rupture rate but relatively more complications after surgical repair, non-surgical treatment is preferred. With a slightly better recovery of sports activity after surgical repair, this might be used as an argument for surgical treatment in young athletes.

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Résumé Entre 1990 et 2001, 292 malades avec une rupture du tendon dAchille ont été admis dans notre institution. Selon le jour de ladmission les malades ont été alloués au Département de Traumatologie ou au Département dOrthopédie. 212 malades (âge moyen 37±9,4 ans) ont été traité par suture chirurgicale suivie dun plâtre pour 6 semaines et 80 malades ont été traités conservativement avec attelle pour 12 semaines. Pour les deux groupes la moyenne de suivi était de 6±3 années. Il y avait 14 ruptures itératives, 10 après réparation chirurgicale et quatre après traitement non chirurgical. Dans le groupe chirurgical il y avait sept problèmes majeurs de paroi, 11 complications mineures de paroi et six malades avec souffrance du nerf sural. Dans le groupe non chirurgical un malade a eu une embolie pulmonaire après une rupture itérative, trois mois après la rupture initiale. Il ny avait aucune différence dans le score moyen de la cheville et le score de satisfaction des malades entre les deux groupes. Seulement 52% ont regagné leur niveau dactivité sportive original, légèrement mieux dans le groupe traité chirurgicalement. Avec une différence non significative dans le taux des ruptures itératives mais relativement plus de complications après réparation chirurgicale, le traitement non - chirurgical est préféré. La récupération sportive légèrement meilleure après réparation chirurgicale est un élément de discussion pour le traitement chirurgical chez les jeunes athlètes.

     

多发性肋骨骨折手术和非手术治疗的疗效对比研究

目的：分析探讨手术和非手术方法治疗多发肋骨骨折的临床效果。方法选取2011年6月至2014年6月本院多发性肋骨骨折患者126例,根据治疗方法不同将所有病例随机平分为观察组和对照组,分别行手术治疗和非手术治疗。治疗后观察两组病例观察两组病例下地功能锻炼时间、住院时间、骨折愈合时间、视觉模拟评分（VAS）、 CRP测定、肋骨骨折治疗疗效评估及术后并发症发生情况。结果通过上门或电话方式行2~24个月随访,平均（13.72±2.53）个月。观察组在治疗后下床功能锻炼时间、住院时间、骨折愈合时间均明显优于对照组,比较具有统计学意义,P＜0.05。观察组治疗后视觉模拟评分（VAS）、CRP测定参数、治疗疗效评估均显著优于对照组,改善明显,比较具有统计学意义,P＜0.05。观察组治疗后并发症发生率低于对照组,比较具有统计学意义,P＜0.05。结论采用手术方法治疗多发肋骨骨折,可有效缩短下地功能锻炼时间、住院时间及骨折愈合时间,治疗后疼痛缓解更快,临床疗效显著,并发症发生率低,适合临床广泛应用。     

A practical electrophysiological guide for non-surgical and surgical treatment of carpal tunnel syndrome

In the present study, we illustrate the use of an electrophysiological classification as a guide to the treatment of carpal tunnel syndrome (CTS). A total of 113 CTS patients were assessed with symptom severity scores, hand functional scores and electrophysiological studies. By setting criteria of electrophysiological tests, 179 hands in 113 patients were classified into mild, moderate and severe degrees of CTS. Of these, the 41 hands with severe CTS were referred for surgery. The 58 hands with moderate CTS and 80 hands with mild CTS received conservative treatment. The improvement ratios in the severe group were greater than that in the moderate and mild groups, both at 6 months and at 1 year. Eighteen hands with moderate or mild CTS returned to normal electrophysiology with the conservative treatments. No patient recovered to normal electrophysiology in the severe group. This electrophysiological classification is objective and it may serve as a useful guide for non-surgical and surgical treatment of CTS.     

Indication and results of surgical treatment of intermittent claudication]

In order to clarify the propriety of surgical treatment for intermittent claudication caused by arteriosclerosis obliterans (ASO), indication for vascular reconstruction and efficacy of surgery on patient's quality of life were investigated. Bypass surgery or laser angioplasty (PTLA) was undertaken in 149 of 188 ASO patients. Because of high risk factors (renal failure, ischemic heart disease, cerebro-vascular disturbance or malignant tumor), 39 patients were treated conservatively. Intellectual dysfunction in aged patient was evaluated by Okabe's brief mental scale test. Coronary artery disease was revealed by coronary angiography performed next to routine dipyridamole-loaded ECG in 19 to 78 patients. CABG or PTCA was performed prior to peripheral vascular reconstruction in 3 patients with serious coronary disease. Extra-anatomical bypass or PTLA was indicated mainly in patients with coronary artery disease or intellectual dysfunction. The anatomical bypass and the extra-anatomical bypass were undertaken in 88 and 61 patients respectively. Graft occlusion was observed in 8 cases. Patency rate of the anatomical bypass was 96.6% and that of the extra-anatomical bypass was 91.8%, at 32 months of postoperative mean follow-up period. The operative mortality rate was 2.7%. There was no major amputation due to graft occlusion.     

The surgical treatment of patients treated with cytostatic chemotherapy

Surgical interventions during or immediately following cytostatic therapy carry an increased risk of complications such as healing disturbances, septic complications or organ insufficiencies. These complications can also be expected if chemotherapy follows the surgical treatment. As the possible complications depend on the class of substances used as well as the time of application these risks can be taken into consideration in multimodal treatment plans. In cases of emergency surgical interventions during chemotherapy or because of tumor based complications there is of course minimal influence to be exerted on the complication rate except through very diligent anastomosis sutures and wound closure.     

The surgical treatment of patients with thyrotoxic goiter]

The results of operative treatment of 1247 patients with thyrotoxic goiter are presented. Thyrotoxic crisis occurred in 0.9%, paresis of the inferior laryngeal nerve--in 1.0%, parathyroid insufficiency--in 0.8%, hypothyrosis--in 2.3% of the patients operated on. The postoperative lethality was 0.2%.     

Outcome between surgical and non-surgical treatment of metastatic tumors of the spine: a retrospective study of 259 patients

AIM: The purpose of this study was to evaluate the clinical outcome of patients with metastatic tumors of the spine after surgical and non-surgical treatment. METHODS: The charts of 259 patients with metastatic tumors of the spine were reviewed retrospectively to define predictors of outcome. Our data included patient demographics, primary tumor, location of the metastatic tumor within the spine, indication for surgical or non-surgical treatment, type of surgical and non-surgical intervention, post-treatment outcome in terms of neurology, use of adjuvant radiation therapy or systemic therapy. RESULTS: The most frequent indication for surgical treatment was the combination of neurological deficit (ND), pathological vertebral fracture, and pain (50 %). Surgical intervention was performed by the posterior approach in 67 %, by the anterior approach in 13 %, and by an anterior/posterior approach in 10 %. The post-surgical outcome, depending on the type of surgical approach in terms of ND, was for the posterior approach 29 % improved, for the anterior approach 53 % improved, and for the anterior/posterior approach 15 % improved. DISCUSSION: Our data suggest that the indications for metastatic tumor surgery in the spine depend on the location of the metastatic tumor in the spine, clinical symptoms, and prognosis.     

手术与非手术治疗腰椎间盘突出症远期疗效的比较评价

[目的]评价腰椎间盘突出症患者手术治疗与非手术治疗的远期疗效.[方法]对2000年1月～2002年12月在本院住院治疗的377例腰椎间盘突出症患者进行随访,分析患者手术和非手术治疗前后VAS、ODI的改善情况,同时比较手术和非手术治疗后SF - 36生活量表的变化.[结果]共获得有效随访99人,随访率为26.3％.下腰痛VAS评分,手术组(52例)术前:5.84,末次随访:1.78.非手术组(47例)治疗前:6.03,末次随访:2.17,两组治疗前后下腰痛VAS评分有显著差异,但两组疗效间没有显著差异.下肢放射痛VAS评分,手术组(52例)术前:7.45,末次随访:1.52;非手术组(47例)治疗前:5.72,末次随访:2.21,两组治疗前后下肢痛VAS评分有显著差异,两组疗效间有显著差异.Oswestry伤残指数(ODI),手术组(52例)术前:68.18％,末次随访:13.44％;非手术组(47例)治疗前:60.98％,末次随访:17.04％,两组治疗前后ODI有显著差异,两组间没有显著差异.SF - 36生存质量调查问卷评分结果显示,治疗后手术组与非手术组相比患者在躯体健康(PF)、躯体角色功能(RP)、躯体疼痛(BP)、生命活力(VT)、情绪角色功能(RE)等5个维度上没有显著性差异(P＞0.05);总体健康(GH)、心理健康(MH)和社会功能(SF)手术组较非手术组有显著性差异(P＜0.05).[结论]本组随访资料显示腰椎间盘突出症手术组和非手术治疗组均有较好的远期疗效.手术治疗能更好地缓解腰椎间盘突出症患者的下肢放射痛,对恢复患者的总体健康、心理健康和社会功能也有积极作用.     

肝门部胆管癌患者的手术治疗

目的：探讨影响可手术切除的肝门部胆管癌患者预后的相关因素。
方法：对6年间行手术切除的44例肝门部胆管癌患者的临床资料和生存情况进行回顾性分析。
结果：44例手术切除的类型,R0切除38例,R1切除6例,R2切除0例。25例患者切除后采用了将空肠袢断端前壁与胆管残端开口上方肝脏断向缝合的新胆管空肠吻合方式,19例患者采用了传统的胆肠吻合方式,新的吻合方式较传统吻合方式可明显减低胆瘘的发生(χ2=4.565, P=0.033)。单因素分析显示,影响患者术后生存期的因素为肿瘤的临床分期、手术切除的范围、是否R0切除以及淋巴结是否转移;而多因素分析显示,影响生存的独立危险因素为肿瘤的临床分期和是否R0切除(P＜0.05)。
结论：影响术后肝门部胆管癌生存期的因素为肿瘤的临床分期和R0切除;采用新的吻合方式,可在尽量减少正常肝组织切除的条件下,保证肿瘤切除的彻底性。