表面处理对Cercon氧化锆陶瓷黏结强度的影响

目的:探讨适合牙科氧化锆陶瓷黏结的表面处理方法。方法:将烧结后的氧化锆陶瓷片分为4组,每组16片,分别采用4种方式(不处理,HF酸蚀 硅烷偶联剂,喷砂 硅烷偶联剂,硅烷偶联剂)处理氧化锆陶瓷片表面并与树脂黏结剂黏结,在水浴24h和水浴30d后测试其黏结抗剪强度,数据用SAS6.12软件加以统计分析,用扫描电镜观察4种处理后的陶瓷表面形貌。结果:喷砂处理后的氧化锆陶瓷的黏结强度为:(34.7±3.44)MPa(水浴24h),(31.5±3.34)MPa(水浴30d),和其他组黏结强度差别有统计学意义(P<0.01),而其他3组间差别均无统计学意义(P>0.05)。结论:喷砂处理的氧化锆陶瓷的黏结强度最高,喷砂是适合牙科氧化锆陶瓷黏结的表面处理方法。     

4种黏结剂与氧化锆陶瓷黏结剪切强度的比较

目的:探讨氧化锆陶瓷与牙本质间合适的黏结材料。方法:将烧结喷砂后的氧化锆陶瓷片分为4组,每组8片,将经过唾液污染→水冲洗→磷酸凝胶(含35%正磷酸)酸蚀→水冲洗处理过的氧化锆陶瓷片分别选用Multilink Automix、3M RelyXTM Unicem AplicapTM、Tokuso Ionomer和Shofu Polycarboxylate Cement等4种黏结材料与牙本质进行黏结,水浴24h后,测试其黏结剪切强度。采用SPSS12.0软件包比较不同黏结剂所得的黏结剪切强度以及黏结的破坏形式。结果:Multilink Automix的黏结抗剪强度最高,3M RelyXTM Unicem AplicapTM次之,但亦显著高于Tokuso Ionomer和Shofu Polycarboxylate Cement,差别有统计学意义(P<0.05)。结论:全酸蚀树脂黏结系统是牙科氧化锆陶瓷黏结的理想选择,可以获得较高的黏结强度。     

氧化锆陶瓷与三种树脂粘接剂粘接剪切强度比较

目的探讨适合牙科氧化锆陶瓷的粘接材料。方法将烧结后的氧化锆陶瓷片分为3组,每组32片,分别采用三种自酸蚀粘接剂RelyX Unicem、PanaviaTM F、Superbond C﹠B与喷砂后的氧化锆陶瓷片粘接,水浴24h和水浴30d后,测试其粘接剪切强度。数据用SAS9.12软件进行统计学分析,粘接断面用扫描电镜观察。结果 PanaviaTMF树脂粘接材料粘接强度最好,分别为（31.36±3.49）MPa（水浴24h）、（29.52±3.44）MPa（水浴30d）。Superbond C﹠B能够取得较好的初期粘接强度（31.85±3.61）MPa（水浴24h）,但水浴30d后明显下降至（21.32±2.58）MPa,P〈0.05。RelyX Unicem的初期（水浴24h）粘接强度最小为（13.29±3.05）MPa,P〈0.0001,但水浴30d后粘接强度为（12.06±2.28）MPa,未见明显降低,P（0.05。结论含有MDP磷酸单体的树脂粘接材料可以使牙科氧化锆陶瓷获得最好的粘接效果。使用不含无机填料的化学固化型纯树脂粘接剂可以取得较好的初期粘接强度但长期效果欠佳。一步法自酸蚀树脂粘接剂虽然没有很高的初期粘接强度,但粘接效果尚能持久。     

溶胶-凝胶法制备硅涂层提高牙科高强度陶瓷与复合树脂的粘接强度

目的:探讨溶胶-凝胶法在牙科高强度陶瓷表面改性对陶瓷和复合树脂粘接强度的影响。方法:喷砂玻璃氧化铝陶瓷和氧化锆陶瓷片各72片,每种陶瓷随机分为4组,每组18片,采取以下处理:A组,硅烷偶联剂;B组,20%硅溶胶涂层+硅烷偶联剂;C组,30%硅溶胶涂层+硅烷偶联剂;(D)40%硅溶胶涂层+硅烷偶联剂,制作陶瓷-复合树脂粘接体;每组样本再分为2个亚组,分别在37℃水浴中放置24 h和30 d后,测定陶瓷和树脂的剪切粘接强度。结果:2种陶瓷水浴24 h后,各涂层组粘接强度与单纯硅烷偶联剂组相比差异有统计学意义,其中30%硅溶胶处理组的粘接强度最高(P<0.05)。水浴30 d后,各组粘接强度均和水浴初期(24 h)相比差异无统计学意义,30%硅溶胶处理组的粘接强度最高(P<0.05)。结论:牙科氧化铝陶瓷和氧化锆陶瓷经过溶胶凝胶法纳米硅涂层表面改性结合硅烷偶联剂的处理可以显著提高陶瓷和树脂的粘接强度,并保持较好的粘接耐久性,30%硅溶胶提高粘接强度的效果最好。     

不同剂型玻璃离子水门汀对牙本质粘结剪切强度的比较

目的:比较不同剂型玻璃离子水门汀对牙本质粘结剪切强度,为临床使用提供参考。方法:临床收集新鲜拔除的磨牙30个,用慢速精密齿科片切机切取颊面浅层牙本质薄片(片厚2 mm),自凝塑料包埋,仅暴露颊侧浅层面作为粘结面,流水冲洗4 s,无油气体吹干,于每个试件的粘结面上固定一直径4 mm,高2 mm成型管。然后将30个试件随机分为3组(每组10个),分别使用RelyXTM Luting Cement(粉液剂型)、GC Fuji PLUS(粉液剂型)和GC Fuji CEM(双糊剂型)3种玻璃离子水门汀进行充填,制作粘结试件后,试件置于盛有人工唾液的容器中37℃24 h,用万能测试机测定每个试件的粘结剪切强度。结果:3种玻璃离子水门汀的粘结剪切强度由底到高分别为:RelyXTM Luting Cement(粉液剂型)(6.163±1.177)MPa、GC Fuji PLUS(粉液剂型)(8.004±0.962)MPa、GC Fuji CEM(双糊剂型)(10.31±0.893)MPa,三者间差异有统计学意义(P<0.05)。结论:双糊剂型玻璃离子水门汀抗粘结剪切强度明显高于两种粉液剂型玻璃离子水门汀,是临床修复治疗的良好选择。     

纳米硅涂层对Cercon氧化锆陶瓷与牙本质黏结强度的影响

目的:探讨利用溶胶凝胶法进行纳米硅涂层表面处理对Cercon氧化锆陶瓷黏结强度的影响.方法:将烧结后的氧化锆陶瓷分为4组,每组16片,分别采用4种方式(空白对照、喷砂、喷砂+硅烷偶联剂、喷砂+纳米硅涂层+硅烷偶联剂)处理氧化锆陶瓷片表面,并通过树脂黏结剂与牙本质黏结,在水浴24h后测试其黏结剪切强度.采用SAS6.12软件包对数据进行方差分析,用扫描电镜观察处理后的陶瓷表明形貌.结果:喷砂+纳米硅涂层+硅烷偶联剂表面处理的氧化锆陶瓷的黏结强度最高,与其他各组黏结剪切强度的差别均有显著性(P=0.000):喷砂+硅烷偶联剂组与喷砂组之间差别无统计学意义(P=0.827);喷砂+硅烷偶联剂组和喷砂组与空白组比较均有统计学意义(P=0.001).结论:通过溶胶凝胶法在喷砂后的陶瓷表面制备纳米硅涂层配合使用硅烷偶联剂.可以显著提高Cercon氧化锆陶瓷的黏结强度.     

三种黏结材料黏结强度的比较

目的比较三种黏结系统(Tyrian/One-Step Plus;Prime & Bond NT;GIC TYPE Ⅱ)在体外环境下的黏结强度.方法18个新鲜拔除的第三磨牙,用低速金刚砂切片机去除咬合面釉质层和根分叉以下牙体,暴露牙本质层.600目湿砂纸打磨后随机选择三种材料按厂家说明在牙本质表面进行黏结处理,并修复方形树脂"冠",将样本保存于室温(25℃)蒸馏水中24 h后,用金刚砂切片机垂直于黏结界面,将牙齿制成约0.9 mm厚的牙片,每片再切成约0.9 mm宽的柱状小条,将小条放置于微拉伸测试仪上,进行黏结强度测试并进行统计学分析.结果三种黏结系统的微拉伸黏结强度平均值间有显著差异(P=0.000),三种材料的微拉伸黏结强度依次为(28.45±10.79)MPa、(14.75±7.41)MPa、(2.63±1.72)MPa.结论Tyrian/One-Step Plus 黏结系统的黏结性能最好.     

不同处理剂对氧化锆与正畸托槽间黏结强度的影响

目的:比较不同表面处理剂对氧化锆修复体表面与正畸托槽间黏结强度的影响.方法:将50个氧化锆陶瓷试件随机分为5组(n=10),进行喷砂和磷酸处理,A组为对照组;B组以硅烷偶联剂处理;C组以硅烷偶联剂+SE Bond 处理;D组以Z-PrimeTM Plus氧化锆处理剂处理;E组以Z-PrimeTM Plus+SE Bond处理.所有试件均用3M Transbond 光固化树脂黏结剂与右上中切牙的托槽黏结,经24 h、37℃恒水浴后,进行抗剪切强度测试;去除托槽后,对氧化锆表面黏结剂残留指数进行统计.其中,每组1个氧化锆表面处理后用扫描电镜观察其表面形态变化,并对氧化锆及处理剂进行红外光谱分析.采用SPSS17.0软件包对数据进行统计学分析.结果:各组的抗剪切强度分别为A组(3.12±0.84) MPa、B组(1.92±0.83) MPa、C组(5.26±0.80) MPa、D组(6.54±0.98)MPa和E组(9.47±2.11) MPa,各组间差异均具有显著性(P＜0.05).A组和B组残留指数最低,E组最高.D组和E组达到了有效的黏结强度.结论:单独使用氧化锆处理剂能获得有效的黏结强度,但是略偏低.建议Z-PrimeTM Plus+SE Bond处理联合使用,以达到正畸临床所需的较高的黏结强度.     

氨化硝酸银染色对牙本质黏结试样黏结强度的影响

目的:评价氨化硝酸银染色对正常及龋损牙本质黏结试样黏结强度的影响。方法:选择30个面龋离体磨牙,去除龋检液染色的龋损组织并磨平牙本质。将牙齿分成3组,分别应用黏结剂Contax(CT)、AdperPrompt(AP)及Prime&BondNT(NT),然后在其上制作复合树脂冠。24h后顺牙齿长轴分别从近远中向及颊舌向片切牙齿,制作截面为1mm2的条状试样,分为龋损牙本质组(CAD)和正常牙本质组(ND),分别浸泡氨化硝酸银(染色组)和浸水(对照组)后测定拉伸黏结强度。结果:染色组黏结强度(MPa)(ND/CAD):CT:28.87±7.76/27.20±6.71,AP:22.93±5.59/20.25±3.51,NT:20.08±3.70/17.99±2.87,对照组黏结强度(MPa)(ND/CAD):CT:27.63±7.31/26.36±8.62,AP:21.62±5.10/21.38±3.96,NT:20.79±3.11/19.02±3.72,各黏结剂染色组与相应的对照组黏结强度无显著差异。结论:硝酸银染色对龋损内层和正常牙本质黏结试样黏结强度无显著影响,龋损内层牙本质的早期黏结强度与正常牙本质无显著差异。     

牙科氧化锆陶瓷与Vitadur alpha瓷及自制饰面瓷热匹配性能的研究

目的:检测牙科氧化锆陶瓷与V itadur alpha、两种自制饰面瓷材料的界面结合性能,以利于进一步研究应用。方法:采用粉浆涂塑法将V itadur alpha及两种饰面瓷材料按照烧结程序分别烧结于氧化锆陶瓷上,检测界面抗剪切强度,并进行抗热冲击性能测试,研究不同材料界面结合性能。结果:V itadur alpha、两种饰面瓷材料G-1、G-2与氧化锆烧结后,在给定温度范围内未出现开裂现象,G-2与氧化锆陶瓷界面抗剪切强度(36.22±5.77)MPa高于V itadurα组结果(27.83±2.75)MPa及G-1组结果(30.76±3.81)MPa,各组结果之间无统计学差异(P>0.05)。结论:V itadur alpha、饰面瓷材料G-1和G-2能够与氧化锆陶瓷支架材料匹配,可以作为饰面瓷材料进行进一步研究。     

Effect of time on the shear bond strength of glass ionomer and composite orthodontic adhesives

The purpose of this study was to compare the effects of time on the shear bond strength of a resin-reinforced glass ionomer and a composite adhesive system specifically (1) within half an hour after bonding the bracket to the tooth and (2) at least 24 hours from the time of bonding when the adhesive has achieved most of its bond strength. Ninety-one freshly extracted human molars were collected and stored in a solution of 0.1% (weight/volume) thymol. The teeth were cleaned and polished. The teeth were randomly separated into four groups: Group I, glass ionomer adhesive debonded within 30 minutes from initial bonding; Group II, glass ionomer adhesive debonded after 24 hours immersion in deionized water at 37 degrees C; Group III, composite adhesive debonded within 30 minutes from initial bonding; Group IV, composite adhesive debonded after 24 hours immersion in deionized water at 37 degrees C. The results of the analysis of variance comparing the 4 experimental groups (F = 59. 3) indicated the presence of significant differences between the 4 groups (P =.0001). In general, the shear bond strengths were significantly greater in the 2 groups debonded after 24 hours. This was true for both the resin-modified glass ionomer (x = 8.8 +/- 3.6 MPa) and the composite (x = 10.4 +/- 2.8 MPa) adhesives. On the other hand, the shear bond strengths were significantly lower in the 2 groups debonded within 30 minutes of their initial bonding. The bond strength of the resin-modified glass ionomer adhesive (x = 0.4 +/- 1.0 MPa) was significantly lower than that for the composite (x = 5.2 +/- 2.9 MPa) adhesive. The present findings indicated that the resin reinforced glass ionomer adhesive has a significantly lower initial bond strength but increased more than 20-fold within 24 hours. In comparison, the composite adhesive has a significantly larger initial bond strength that doubled within 24 hours. The clinician needs to take these properties into consideration when ligating the initial arch wires.     

Tensile and shear bond strength of resin-reinforced glass ionomer cement to glazed porcelain

The purpose of this study was to measure the tensile and shear bond strength of resin-reinforced glass ionomer cement (RGIC) to glazed porcelain, to evaluate the durability of RGIC by thermal cycling, and to examine the RGIC remaining on the surface of the porcelain after the bond strength test to evaluate bonding conditions. Three adhesives were used in this study: Concise (CO) as a chemically cured composite resin, Fuji ORTHO (FO) as a chemically cured RGIC, and Fuji ORTHO LC (FOLC) as a light-cured RGIC. Tensile and shear bond strengths were measured 24 hours after bonding orthodontic brackets and also after thermal cycling. Tensile bond strength after 24 hours was 6.6 +/- 3.2 MPa in CO, 7.3 +/- 1.4 MPa in FO, and 8.6 +/- 1.9 MPa in FOLC, and the strength significantly decreased after the thermal cycling test. Shear bond strength after 24 hours was 32.5 +/- 8.9 MPa in CO, 23.3 +/- 6.8 MPa in FO, and 24.7 +/- 6.5 MPa in FOLC, and in contrast to tensile bond strength, no decreases in the strength were detected after the thermal cycling test. CO showed significantly higher shear bond strength than did FO and FOLC. When using the shear bond strength test and CO, destruction of porcelain surfaces frequently occurred after 24 hours and was observed in every specimen after the thermal cycling. RGIC was found to be an advantageous alternative to resin adhesive for bracket bonding to porcelain and to enamel.     

用于正畸托槽粘接的玻璃离子粘固剂的抗剪切强度

目的　研究用于正畸托槽粘接的树脂改良型玻璃离子粘固剂的抗剪切强度。方法　 30颗离体前磨牙平均分为 2组。一组用树脂改良型玻璃离子粘固剂 (Advance)粘接方丝弓正畸托槽 ,另一组用复合树脂釉质粘接剂 (DM)粘接。 2 4h后用材料力学试验机检测两种材料的抗剪切强度 ,统计牙面上粘接材料的残留指数。结果　 2种粘接材料的抗剪切强度相似 [玻璃离子粘固剂为 (6 86 2±2 142 )MPa,复合树脂粘接剂为 (7 183± 3 2 0 5 )Mpa],差异无显著性。结论　体外研究中 ,树脂改良型玻璃离子粘固剂的抗剪切强度已达到复合树脂釉质粘接剂的水平 ,具有临床应用前景     

光固化树脂加强型玻璃离子水门汀即刻剪切强度的测定

目的研究光固化树脂加强型玻璃离子水门汀黏结正畸托槽的即刻剪切强度。方法收集离体前磨牙30颗,随机均分为3组。第1组(对照组):35%磷酸酸蚀30 s,冲洗、干燥,涂黏结剂,京津釉质黏结剂黏结托槽。第2、3组:35%磷酸酸蚀30 s,冲洗,湿润,光固化型的Fuji Ortho Lc树脂加强型玻璃离子黏结托槽。第1、2组24 h后测剪切强度,第3组30 min内测剪切强度。托槽去除后统计牙面上的黏结剂残留量。结果第2组的剪切强度高于第3组,差异有显著性;第1、3组间剪切强度差异无显著性。结论光固化树脂加强型玻璃离子水门汀的即刻黏结强度能够满足临床要求,但24 h后的黏结强度显著增强。     

Influence of surface characteristics of four silica-based machinable ceramics on flexural strength and bond strength of a dual-curing resin luting agent

PURPOSE: The aim of the present study was to evaluate the crystalline phase and microstructure of 4 commercial machinable ceramic blocks--Cerec Vitablocs Mark II (Vita), ProCAD (Ivoclar/Vivadent), GN-I (GC), and GNCeram (GC)--and compare flexural strength and shear bond strength between a dual-curing resin luting agent and the ceramics treated with a silane coupling agent. MATERIALS AND METHODS: Specimens were examined using scanning electron microscopy/energy-dispersive x-ray spectroscopy, and x-ray diffractometry. Three-point bending tests were performed with polished specimens 20 mm long, 4 mm wide, and 1.2 mm thick. Two differently shaped specimens for each of the 4 machinable ceramics were treated with a silane coupling agent. The specimens were then cemented together with a dual-curing resin luting agent. Half of the specimens were stored in water at 37 degrees C for 24 h and the other half were thermocycled 20,000 times. RESULTS: Chemical composition, crystalline phase, and crystallinity were significantly different between brands. The Vitablocs Mark II material had the significantly lowest flexural strength (101.7 +/- 15.3 MPa), while the GNCeram material had the highest (174.8 +/- 10.3 MPa). The use of a silane coupling agent yielded high shear bond strength after 20,000 thermocycles (Vitablocs Mark II: 37.7 +/- 3.7 MPa, ProCAD: 41.2 +/- 3.1 MPa, GNCeram: 50.2 +/- 2.1 MPa), except with the GN-I material (23.9 +/- 4.4 MPa). CONCLUSION: It appeared that crystal distribution and particle size of leucite crystal, not crystallinity, in the feldspar glass matrix of silica-based machinable ceramics might influence the flexural strength and efficacy of a silane coupling agent in bonding between a dual-curing resin luting agent and machinable ceramics.     

不同粘固前处理方法对氧化锆陶瓷粘结性能的影响

目的　探讨不同粘固前处理方法对被唾液污染的氧化锆陶瓷粘结性能的影响。方法　将烧结喷砂后的氧化锆陶瓷片分为4组,每组6片,（1）空白对照,（2）唾液污染+水冲洗,（3）唾液污染+水冲洗＋75％乙醇处理＋水冲洗,（4）唾液污染+水冲洗＋磷酸凝胶（含35％正磷酸）＋水冲洗,进行表面处理,与树脂粘结剂粘结,水浴24 h后测试其黏结剪切强度,数据用SPSS12.0软件进行统计学分析。结果　对照组的氧化锆陶瓷试件的粘结剪切粘结强度最高,水冲洗组的氧化锆陶瓷试件粘结剪切强度最低。与对照组粘结剪切强度相比,水冲洗组及乙醇处理组的差别均有统计学意义(P<0.05);结论　唾液污染影响牙科氧化锆陶瓷粘结强度;单纯水冲洗及75％乙醇处理不能清除唾液污染的影响。     

Bonding of resin composite luting cements to zirconium oxide by two air-particle abrasion methods

OBJECTIVE: This study evaluated the shear bond strength of two resin composite luting cements to zirconium oxide ceramic substrate using two air-particle abrasion methods. METHODS: Two resin composite cements, RelyX Unicem (3M ESPE) and Panavia F (Kuraray), each with an acidic composition, were used in combination with a zirconium oxide (DCS Dental AG) substrate containing Al2O3 and SiO2 (Rocatec system, 3M ESPE) and two air-particle abrasion methods. The shear bond strength of the resin composite cement to the substrate was tested after the samples were either water-stored for one week or thermocycled following 24 hours of water storage. RESULTS: The RelyX Unicem resin composite cement specimens with the Rocatec treatment (20.9 +/- 4.6 Mpa and 20.1 +/- 4.2 MPa, respectively, n = 12) demonstrated the highest shear bond strength. Alternatively, the lowest values were obtained for the Panavia F resin cement samples, with Al2O3 air-particle abrasion in both storage conditions, water storage for one week (17.7 +/- 8.9MPa) or thermocycling after 24 hours of water storage (16.3 +/- 4.9 MPa). Neither storage condition or particle abrasion system significantly affected shear bond strengths (ANOVA, p > 0.05). CONCLUSION: It was concluded that two different surface conditioning methods and storage conditions did not significantly affect the bonding properties of Panavia F and RelyX Unicem resin composite luting cements to Zirconia.     

Effect of surface conditioning methods on the bond strength of luting cement to ceramics

OBJECTIVES: This study evaluated the effect of three different surface conditioning methods on the bond strength of a Bis-GMA based luting cement to six commercial dental ceramics. METHODS: Six disc shaped ceramic specimens (glass ceramics, glass infiltrated alumina, glass infiltrated zirconium dioxide reinforced alumina) were used for each test group yielding a total number of 216 specimens. The specimens in each group were randomly assigned to one of the each following treatment conditions: (1) hydrofluoric acid etching, (2) airborne particle abrasion, (3) tribochemical silica coating. The resin composite luting cement was bonded to the conditioned and silanized ceramics using polyethylene molds. All specimens were tested at dry and thermocycled (6.000, 5-55 degrees C, 30 s) conditions. The shear bond strength of luting cement to ceramics was measured in a universal testing machine (1 mm/min). RESULTS: In dry conditions, acid etched glass ceramics exhibited significantly higher results (26.4-29.4 MPa) than those of glass infiltrated alumina ceramics (5.3-18.1 MPa) or zirconium dioxide (8.1 MPa) (ANOVA, P<0.001). Silica coating with silanization increased the bond strength significantly for high-alumina ceramics (8.5-21.8 MPa) and glass infiltrated zirconium dioxide ceramic (17.4 MPa) compared to that of airborne particle abrasion (ANOVA, P<0.001). Thermocycling decreased the bond strengths significantly after all of the conditioning methods tested. SIGNIFICANCE: Bond strengths of the luting cement tested on the dental ceramics following surface conditioning methods varied in accordance with the ceramic types. Hydrofluoric acid gel was effective mostly on the ceramics having glassy matrix in their structures. Roughening the ceramic surfaces with air particle abrasion provided higher bond strengths for high-alumina ceramics and the values increased more significantly after silica coating/silanization.     

Cytotoxicity and bonding property of dental ceramics.

OBJECTIVES: Yttria partially stabilized zirconia (YPSZ) ceramic is suitable for dental and medical use because of its high fracture toughness and chemical durability. The purpose of this study was to estimate the cytotoxicity and bonding property of zirconia ceramic compared to other dental ceramics. METHODS: Eight commercial dental ceramics including Denzir (YPSZ) are used in this cytotoxicity test. The human gingival fibroblast (GF) cells were cultured using extraction solutions of ceramics. The cytotoxicity was estimated by two different methods. The bonding strength of Denzir was compared to Empress2 using zinc phosphate, glass ionomer, and adhesive resin cements. A brass plate was prepared with drilled tapered holes and ceramic specimens were prepared to fit the holes and bonded. The bonding strength was estimated by the punching test. RESULTS: No significant (p>0.05) cytotoxicity was observed in all ceramic extractions. The two evaluation methods showed no significant differences. Denzir and Empress2 showed similar bonding strength with zinc phosphate or glass ionomer cement bonding. For both Empress2 and Denzir the glass ionomer cement showed significantly (p<0.001) higher bonding strength compared to the zinc phosphate cement. Empress2 showed significantly higher bonding strength with adhesive resin cement. However, the Denzir showed lower bonding strength with adhesive resin cement. SIGNIFICANCE: No ceramic extractions showed any evidence of cytotoxicity. Therefore, the low in vitro cytotoxicity of ceramic extractions including Denzir was confirmed. Denzir showed a similar bonding strength to Empress2 with zinc phosphate or glass ionomer cement bonding with this testing method and lower bonding strength with adhesive resin cement than with Empress2.