罕见口腔黏膜皮内痣1例

报告1例口腔黏膜皮内痣。患者男,15岁。口腔黏膜肿物15年,近3个月来肿物增长较快。皮损组织病理示:真皮内可见大量呈巢状痣细胞,其内见较多黑素颗粒,细胞成熟未见核分裂相。诊断:口腔黏膜皮内痣。行右下前牙拔除+肿物切除+局部牙槽骨去除术,并予抗感染治疗,创面愈合良好,无复发。     

Nevus Comedonicus on Scalp: A Rare Site

Nevus comedonicus is rare hamartoma of the pilosebaceous unit. Curiously the scalp is rarely involved. Here we are reporting 33-year-old male presenting with nevus comedonicus arranged linearly on the scalp. There was positive family history of similar lesion on the similar site. This case has been presented for its sheer rarity and atypical site.     

Bilateral Systematized Epidermolytic Verrucous Epidermal Nevus: A Rare Entity

Verrucous epidermal nevi are congenital, noninflammatory cutaneous hamartomas composed of keratinocytes. They follow the lines of Blaschko and show hyperkeratosis without cellular atypia. The routine histology shows variable amount of hyperkeratosis, acanthosis and papillomatosis and rarely epidermolytic hyperkeratosis. We saw a 3-year-old boy with bilaterally symmetrical, systematized verrucous plaques along the lines of Blaschko extensively involving the trunk and extremities but sparing the face and palmoplantar skin. Histopathology showed features of epidermal nevi with prominent epidermolytic hyperkeratosis. We report here the case for the rarity of this entity.     

Pigmented Trichoblastoma Arising from the Nevus Sebaceous: A Rare Case in Korea

Trichoblastoma is occasionally observed in association with a pre-existing nevus sebaceous in the Korean literature. However, there has been no report on the pigmented type. Herein, we report the first Korean case of a pigmented trichoblastoma arising from the nevus sebaceous on the forehead. A 28-year-old male presented with a dark nodular lesion within a yellowish plaque on the forehead. The surrounding yellowish plaque on the forehead had existed since birth. The central, dark-pigmented nodule began to appear three years ago and enlarged gradually. Histopathologic findings of central pigmented lesion showed heavy melanin deposits within and around the tumor nests. Complete excision was made as treatment.     

Probable Congenital Melanocytic Nevus of the Oral Mucosa: Case Report

Abstract: There are few case reports of congenital melanocytic nevi affecting the oral mucosa. We report the clinical and histologic features of an Intraoral melanocytic lesion that in our opinion meets the criteria for the diagnosis.     

Giant Congenital Melanocytic Nevus with Developmental Dysplasia of Bilateral Hip: A Rare Association

Giant congenital melanocytic nevi are rare congenital disfiguring benign neoplasms with a risk of transformation to malignant melanoma. They often present with various extra-cutaneous features. Here, we describe a case of giant melanocytic nevus with developmental dysplasia of bilateral hip, a novel association.     

Unilateral Nevus of Ota with Bilateral Nevus of Ito and Palatal Lesion: A Case Report with a Proposed Clinical Modification of Tanino's Classification

Nevus of Ota and nevus of Ito are rare dermal melanocytoses. Nevus of Ota may be very rarely associated with the nevus of Ito and other extra cutaneous features. Both nevi are similar in all respect apart from the area of distribution. Bilateral distribution of nevus of Ito is seldom reported in the literature. A 24-year-old male patient reported with nevus of Ota of the right side of his face since his infancy and nevus of Ito on both shoulder regions since early childhood. He had bluish lesions on the right side of his hard palate. Systemic examination was normal. Relevant laboratory investigations were non contributory. The histopathological examination of the skin from the affected areas showed the presence of elongated dendritic dermal melanocytes. The present case is the first report of an association of bilateral nevus of Ito with nevus of Ota and palatal lesions. Tanino classified Nevus of Ota into four groups. As both the nevi are similar in all respect except the area of distribution, a minor modification of the existing Tanino''s classification to incorporate the nevus of Ito into the classification for the Ota''s nevus may be appropriate.     

Infantile Condylomata of the Oral Cavity

A child had condylomata acuminata localized to the oral cavity. Main points of interest were this exclusive localization, the extremely high number of papillary lesions, not reported in the literature until now, and the excellent response to interferon and local applications of podophyllin. Histologic, ultrastructural, and in situ molecular hybridization techniques were performed to make a correct diagnosis. Transmission of the etiologic agent and therapeutic approaches are discussed.     

二期梅毒口腔黏膜白斑1例

患者男,45岁。口腔溃烂3月。舌面可见红色斑疹,伴浅糜烂,约指甲盖大小,舌背右侧稍肿胀,可见两颗淡红色水肿性结节,约中指头及黄豆大小。躯干皮肤正常,外生殖器无皮疹。RPR1∶64(+),TPPA(+)。诊断:二期梅毒。予普鲁卡因青霉素治疗20天,2个月后复查RPR1∶16(+),TPPA(+),舌背面红斑、糜烂及舌下方结节消退。     

口唇部疣状癌1例

报告 1例临床上少见的口唇部疣状癌。患者男 ,70岁。口唇部有约 12cm× 11cm× 2cm菜花状外生性肿块 ,组织病理具有疣状癌的典型的特征改变 ,HPV定性检测阳性。     

Four Cases of Lobulated Intradermal Nevus: A Sign of Aging Melanocytic Nevus

Melanocytic nevi are subject to change with age in both clinical and histopathologic findings. In 1991, Cho et al. first reported three cases of lobulated intradermal nevi and suggested their cases represented an unusual form of regressing melanocytic nevus. Herein we report four cases of lobulated intradermal nevus and review previous literature.     

Nevus Comedonicus: A Case Series

Twelve previously unreported cases of nevus comedonicus are presented. Characteristic closely grouped dilated follicular openings with horny plugs that mimic comedones led to the diagnosis. One patient had nevus comedonicus syndrome and there were cases with atypical locations and unusual complications of this condition. We also highlight clinical associations and therapeutic options.