机械祛栓治疗急性肺动脉栓塞的实验研究

目的实验性比较经导管机械祛栓、经导管肺动脉内局部溶栓和经导管机械祛栓联合局部溶栓治疗急性肺动脉栓塞疗效和安全性。方法28只杂种犬经数字法随机分为4组,机械祛栓治疗组、局部溶栓治疗组、机械祛栓联合局部溶栓治疗组和对照组(CTL组)各7只。用犬的自体血栓建立急性肺动脉栓塞模型,分别采用经导管予机械祛栓(helix thrombectomy device,HTD)、尿激酶(UK)局部溶栓、机械祛栓联合尿激酶及生理盐水治疗。监测肺动脉平均压(PAMP)、主动脉收缩压(SBP)、血气及肺动脉造影情况。术后取动物肺组织行病理检查。结果在各组中,治疗后PAMP在30min时,CTL组为(33.5±3.38)mm Hg(1mm Hg=0.133kPa),UK组为(29.00±3.96)mm Hg,HTD组为(29.39±3.17)mm Hg,HTD+UK组为(25.24±3.04)mm Hg(q=6.88,P=0.002);60min时,CTL组为(33.19±3.54)mm Hg,UK组为(28.79±3.96)mm Hg,HTD组为(24.44±3.70)mm Hg,HTD+UK组为(23.57±4.57)mm Hg(q=8.73,P=0.000);120min时,CTL组为(31.50±3.75)mm Hg,UK组为(26.43±4.04)mm Hg,HTD组为(22.00±3.62)mm Hg,HTD+UK组为(17.86±3.26)mm Hg(q=17.78,P=0.000)。治疗后30、60和120min与对照组同时相的PAMP相比均明显降低,差异有统计学意义(P<0.05)。HTD组于治疗后120min与UK组同时相PAMP相比差异有统计学意义(P<0.05)。HTD+UK组治疗后30min和120min较UK组和HTD组同时相的PAMP降低更为明显(P<0.05);治疗60min与UK组差异有统计学意义(P<0.05)。治疗后的肺动脉造影表现为阻塞的肺动脉血流完全或不完全再通;充盈缺损减小;相应肺组织血流完全或不完全恢复。病理检查:(1)对照组:所见栓塞部位与肺动脉造影结果一致。光学显微镜下,肺动脉血管内可见血栓,肺组织大片出血灶,部分肺泡腔内大量红细胞。(2)治疗组:肺出血轻,肺泡腔内少量红细胞。HTD操作的相应肺动脉内膜轻微损伤。结论HTD消融器祛栓联合局部溶栓的疗效明显优于单独经导管肺动脉内局部溶栓或HTD消融器祛栓治疗,具较高的安全性。     

静脉溶栓联合导管碎栓和切栓治疗急性大面积肺栓塞

目的评价静脉溶栓联合导管碎栓和切栓治疗急性大面积肺栓塞的临床疗效和安全性。方法对19例急性大面积肺栓塞患者，采用下腔静脉滤器置入、肺动脉导管碎栓和静脉溶栓加低分子肝素抗凝治疗，19例中4例加用了Straub Rotarex导管血栓旋切术。结果19例共行21次治疗。18例经介入治疗后胸闷、紫绀症状均明显改善，肺动脉中央分支血流恢复通畅，血氧饱和度由术前平均86％（74％～96％）上升到治疗后的平均97％（94％～100％）。肺动脉压力从术前的（334-5）mmHg（1mmHg=0．133kPa）下降到术后的（254-5）mmHg（t=13．2，P〈0．01）。l例双侧肺动脉主干大块血栓栓塞的患者，介入治疗无效，后经胸外科手术取栓未能成功，患者死亡。4例成功地采用了Straub Rotarex旋切治疗肺动脉血栓，未出现并发症。结论采用导管碎栓和血栓旋切等介入技术联合静脉溶栓抗凝治疗，是治疗急性大面积肺动脉栓塞的有效而且安全的方法。     

Systemic septic embolisation secondary to an atrial myxoma in a young woman

We present a case of a left atrial myxoma infected with Staphylococcus aureus in a 35-year-old woman who was found to have a retained tampon. Multiple systemic septic emboli were seen on computed tomography imaging of the brain, spleen and kidneys. She was successfully treated by surgical excision of the myxoma and 4 weeks of antibiotic therapy. We postulate that the source of this patient’s S. aureus infection was tampon use, leading to a toxic shock syndrome and causing infection of an undiagnosed left atrial myxoma, which led to the embolisation. As far as the authors are aware, this is the first reported case of such an entity. In those with an underlying cardiac predisposition, tampon use may represent a risk of infection with S. aureus, and we intend to heighten clinical awareness of this potentially life-threatening association. We also discuss the diagnosis, complications and treatment of infected atrial myxoma and illustrate the imaging findings.     

单纯经皮机械祛栓治疗急性大面积肺栓塞的临床应用

目的评价单纯介入机械祛栓在治疗急性大面积肺栓塞(PE)方面的临床疗效和安全性。方法回顾性收集2003年1月到2008年1月经皮机械碎栓(PMT)或(和)Straub Rotarex系统祛栓治疗急性大面积PE病例6例。结果6例患者的肺动脉主干血流得以再通且临床症状改善。介入术后,患者SaO2从术前79.5%±5.3%增加至92.8%±3.4%(P<0.01);PaO2从术前从(58.0±9.8)mmHg增加至(88.7±4.1)mmHg(P<0.01);术后患者的平均肺动脉压(PAP)从(40.8±7.8)mmHg降至(29.8±8.0)mmHg(P<0.01);Miller指数从术前的0.54±0.03降至术后的0.18±0.07(P<0.01)。在完成临床随访的4例患者中,1～5年内均未有PE复发。结论初步临床经验显示单纯PMT是治疗急性大面积PE的一种简单、有效、安全的方法,尤其是针对有溶栓禁忌证的患者。     

Percutaneous mechanical thrombectomy for thrombosed vessels with a hydrolyser (hydrodynamic thrombectomy catheter): clinical experience

A hydrodynamic thrombectomy catheter was prospectively evaluated for the treatment of thrombosed vessels. Seven patients (7 males: age range from 56 to 82 years; mean age: 79 years) presenting with acute or chronic occlusion of peripheral native arteries (n = 6) and dialysis shunt (n = 1) were treated with the hydrolyser (Cordis, Johnson and Johnson, Japan). Mean occlusion time was 135 days (range: 2-300 days), and mean thrombus length 16 cm (range: 5-20 cm). Removal of the thrombus was successful in five patients (71%), regardless of the length of the thrombus. Mean procedure time was 20 minutes (range: 15-30 minutes). No major complications occurred. Adjunctive thrombolysis was required for persistence of the residual thrombosed distal vessel in one patient. Adjunctive balloon angioplasty was performed in two patients (one native vessel and one dialysis shunt), and stent placement was performed in one patient (dialysis shunt). In two unsuccessful cases, the hydrolyser could not be advanced to the distal side because of the solid thrombus. Therefore, thrombolytic therapy was chosen. However, this therapy failed because the guidewire did not pass within the thrombus. Surgery was performed in these two patients. We conclude from this clinical experience that percutaneous thrombectomy with a hydrolyser is a promising technique for the treatment of thrombosed vessels. Especially in the acute stage of thrombosed occlusion, percutaneous thrombectomy with a hydrolyser is superior to thrombectomy with a Fogarty balloon catheter because of its shorter procedure time and fewer complications.     

急性大面积肺梗死的介入机械碎栓治疗

目的探讨急性大面积肺梗死介入机械碎栓治疗的可行性和临床疗效。方法对15例急性大面积肺栓塞患者采用碎栓器械行介入治疗,观察临床症状、肺动脉平均压、血氧分压和肺动脉开通情况。结果疗效评价为11例显效,3例好转,1例无效,术后动脉血氧分压明显升高,由(60.6±7.8)mmHg升至(91.0±7.7)mmHg,P=0.00;肺动脉平均压明显降低由(39.7±10.8)mmHg降至(27.3±7.9)mmHg,P=0.000。结论介入机械碎栓治疗急性大面积肺栓塞是一种可行且行之有效、安全的方法。     

Two-dimensional echocardiography in the diagnosis of intracardiac masses: A prospective study with anatomic validation

The accuracy of two-dimensional echocardiography in the detection of intracardiac masses was verified in 334 patients who underwent cardiac catheterization in our laboratory over 21 consecutive months. A complete two-dimensional echocardiographic (2DE) examination was performed a day before catheterization. The presence or absence of a mass was verified at surgery in 77 patients who successively underwent mitral or aortic valve replacement (51), left ventricular aneurysmectomy with or without myocardial revascularization (25), and resection of atrial myxoma (2). In 32 patients 2DE revealed the presence of a mass-left or right atrial thrombi in 12, left atrial myxoma in 2, left ventricular thrombi in 16, and endocardial vegetations in 2. The other 45 patients were free of intracardiac masses on 2DE. Anatomic verification at surgery revealed the presence of an intracardiac mass in 34 patients. In 30 (true positives) of these, 2DE revealed the mass as well, and in 4 (false negatives) the presence of a mass had not been identified by 2DE. In 2 patients (false positives) the predicted mass was not found at surgery. Absence of a mass was correctly predicted by 2DE in 41 patients (true negatives). Thus 2DE detected intracardiac masses with sensitivity of 88.2% and a specificity of 95.3%. We recommend that 2DE be performed in all patients prior to hemodynamic study and/or cardiac surgery to enable safer management of patients with intracardiac masses during cardiac catheterization and/or cardiac surgery.     

Straub Rotarex System血栓旋切器治疗动脉血栓栓塞的临床应用

目的探讨Straub Rotarex System血栓旋切器治疗动脉血栓栓塞的疗效及应用价值。方法9例下肢动脉栓塞的患者,其中动脉栓塞4例,股动脉栓塞3例,髂动脉栓塞1例,髂动脉闭塞合并动脉栓塞1例。栓塞原因5例为动脉硬化,4例为心脏栓子脱落;病程1 d~5个月;栓塞长度为5~13 cm;对1例左髂动脉闭塞及动脉栓塞患者先行左髂动脉血管内扩张成形及支架置入术后再对动脉血栓行旋切治疗,8例动脉栓塞患者直接采用血管内血栓旋切治疗,对其中2例旋切治疗术后血管狭窄>50%的患者行球囊扩张治疗。术后给予抗凝、抗感染治疗1周。结果9例患者顺利完成了血栓旋切、球囊扩张及支架置入治疗,血栓被清除、血管狭窄消失、血流恢复正常,未出现并发症。结论StraubRotarex血栓旋切器治疗动脉血栓栓塞是一种安全、高效的新方法,具有较高的临床应用价值。     

Straub Rotarex System血栓栓塞的临床应用血栓旋切器治疗动脉

目的 探讨Straub Rotarex System血栓旋切器治疗动脉血栓栓塞的疗效及应用价值。方法9例下肢动脉栓塞的患者，其中胭动脉栓塞4例，股动脉栓塞3例，髂动脉栓塞1例，髂动脉闭塞合并胭动脉栓塞1例。栓塞原因5例为动脉硬化，4例为心脏栓子脱落；病程1d～5个月；栓塞长度为5～13cm；对1例左髂动脉闭塞及胭动脉栓塞患者先行左髂动脉血管内扩张成形及支架置入术后再对胭动脉血栓行旋切治疗，8例动脉栓塞患者直接采用血管内血栓旋切治疗，对其中2例旋切治疗术后血管狭窄〉50％的患者行球囊扩张治疗。术后给予抗凝、抗感染治疗1周。结果9例患者顺利完成了血栓旋切、球囊扩张及支架置入治疗，血栓被清除、血管狭窄消失、血流恢复正常，未出现并发症。结论 Straub Rotarex血栓旋切器治疗动脉血栓栓塞是一种安全、高效的新方法，具有较高的临床应用价值。     

AngioJet机械性血栓清除装置治疗急性肠系膜上动脉栓塞初步临床效果

【摘要】 目的 探讨AngioJet机械性血栓清除装置治疗急性肠系膜上动脉栓塞（ASMAE）的可行性、安全性和有效性。 方法 回顾性分析2017年4月至2020年1月收治的12例ASMAE患者。其中男6例,女6例,年龄为（74.4±10.5）岁;肠系膜上动脉起始段闭塞1例,中段闭塞7例,起始段＋中段闭塞4例。采用AngioJet装置实施肠系膜上动脉血栓清除,对治疗后还存在血管残余狭窄者予以球囊扩张成形和/或支架植入。术后早期根据症状、体证评估疗效,术后1、3、6 个月进行腹部增强CT检查评估肠系膜上动脉通畅情况。 结果 所有患者均顺利完成抽栓治疗,技术成功率100%。抽吸时间为30～161 s,平均（81.0±39.3） s;术中尿激酶用量（10～30）×104U,平均（15.8±6.7）×104U。8例肠系膜上动脉栓塞部位完全再通,4例行补充性球囊扩张和/或支架治疗后血管恢复通畅,其中2例单纯扩张、1例支架植入、1例球囊扩张结合支架植入。无动脉损伤和肾功能损害等并发症。临床有效11例,无效1例,死亡1例。术后第1、3、6个月门诊随访,患者无腹痛、黑便、腹泻等症状。11例患者CTA检查提示肠系膜上动脉管腔血流通畅,无狭窄/闭塞表现。结论 AngioJet机械性血栓清除装置治疗ASMAE方法安全可行,初步临床疗效满意。     

颅内静脉窦血栓形成的抗血栓治疗方案研究进展

颅内静脉窦血栓形成（CVST）是一种特殊类型的脑卒中,其危险因素及临床症状多样,易被漏诊或误诊。目前尚无关于CVST的治疗指南,其最佳治疗方法仍存在争议。抗凝治疗是该病的重要治疗手段,同时该病较高的致残率和致死率促进了血管内介入治疗的发展。本文就该病临床中抗血栓治疗的抗凝治疗方案、血管内介入治疗方案（溶栓治疗及机械取栓治疗）进展进行综述,以提高对治疗的认识,降低致死率、致残率。     

MDCT in the diagnostic algorithm in patients with symptomatic atrial fibrillation

Atrial fibrillation(AF) is the most common supraventricular arrhythmia and a major cause of morbidity.Arrhythmogenic foci originating within the pulmonary veins(PVs) are an important cause of both paroxysmal and persistent AF.A variety of endovascular and surgical techniques have been used to electrically isolate the PV from the left atrium.Pulmonary venography for localization of the PV ostium can be difficult to perform during the ablation procedure.While the anatomy of the PV is patientspecific,non-invasive imaging techniques may provide useful diagnostic information prior to the intended intervention.In this context,multidetector computed tomography(MDCT) visualization of the left atrial and PV anatomy prior to left atrial ablation and PV isolation is becoming increasingly important.MDCT imaging provides pre-procedural information on the left atrial anatomy,including atrial size and venous attachments,and it may identify potential post-procedural complications,such as pulmonary vein stenosis or cardiac perforations.Here,we review the relevant literature and present the current"state-of-the-art"of left atrial anatomy,PV ostia as well as the clinical aspects of refractory AF with MDCT imaging protocols and procedural aspects of PV ablation.     

螺旋CT肺动脉造影对于肺动脉栓塞的诊断价值(附8例报告)

目的评价螺旋CT肺动脉造影对于肺动脉栓塞的诊断及随访观察溶栓疗效的可靠性和准确性。方法经我院螺旋CT肺动脉造影诊断的8例肺动脉栓塞患者中有5例进行溶栓治疗。结果8例患者共有17处肺动脉及分支受累。动脉栓子呈偏于管腔一侧的突起状、不规则状和位于管腔中心的柱状及完全堵塞状态。5例溶栓治疗后有3例栓子完全消失，2例栓子明显缩小。结论螺旋CT肺动脉造影在诊断肺动脉栓塞和治疗随访观察疗效过程中都有着重要的价值，可望成为肺动脉栓塞诊断的首选方法。     

Percutaneous radiofrequency ablation of lung tumors with expandable needle electrodes: current status

Percutaneous radiofrequency thermal ablation (RFA) has been used to treat primary and secondary liver tumors under ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI) guidance for the past decade [Park et al., Radiol Clin North Am 38:545–561, 2000; Siperstein and Gotomirski, Cancer J 6:S293–S301, 2000; Kelekis et al., Eur Radiol 13:1100–1105, 2003]. RFA is a low-cost, minimally invasive treatment that has recently attracted attention for treating tumors in different solid organs with promising results [Dupuy and Goldberg, J Vasc Interv Radiol 12:1135–1148, 2001; Friedman et al., Cardiovasc Intervent Radiol 27:427–434, 2004]. It can be provided with minimal hospitalization, and experienced practitioners have reported low complication rates [Dupuy and Goldberg, J Vasc Interv Radiol 12:1135–1148, 2001; Livraghi et al., Radiology 226:441–451, 2003]. Patients with lung malignancies (primary lung cancer or pulmonary metastases), who cannot be operated, might be candidates for RFA treatment. It can also be used in association with other treatments (i.e., chemotherapy, radiotherapy) for better disease control. Combination of the above with RFA may help reduce morbidity and mortality. Many ways to apply energy to the tumor exist (monopolar and bipolar RFA, microwave, laser, brachytherapy). In this review we will focus on expandable monopolar systems, which despite their deficiencies are the most popular in the interventional radiology sector.     

经导管封堵治疗合并肺动脉高压的老年继发孔房间隔缺损

目的评估经导管封堵治疗合并肺动脉高压的老年继发孔房间隔缺损(房缺)的疗效和安全性。方法2002年1月-2006年12月于我院行房缺封堵术的34例患者入选本研究,其中15例老年合并肺动脉高压的继发孔房缺患者作为肺动脉高压组。全部患者均在术前、术后1d、1、3、6和12个月行经胸心动超声图和12导联心电图检查。在透视及经胸心动超声图引导下经导管植入Amplatzer封堵器闭合房缺。结果所有患者封堵器植入均获成功,术中和术后均无并发症发生。肺动脉高压组与非肺动脉高压组年龄分别为(67±5)岁和(24±9)岁,(P<0.01),心功能分级分别为2.8±0.7和1.7±0.7,(P<0.01),房缺直径分别为(30.5±3.2)mm和(14.2±4.0)mm(P<0.01),封堵器直径分别为(35.3±4.5)mm和(18.2±4.4)mm(P<0.01),肺动脉收缩压分别为(65.2±11.2)mmHg和(29.5±3.3)mmHg(P<0.01)肺动脉平均压分别为(31.0±4.4)mmHg和(17.9±1.1)mmHg(P<0.01),封堵后,肺动脉高压组患者的肺动脉收缩压为(36.6±11.4)mmHg,肺动脉平均压为(21.6±4.3)mmHg,均有明显下降,两者与术前比较P均<0.01,心功能有明显提高(从术前2.8±0.7增加到1.8±0.8,P<0.01)。结论经导管封堵治疗合并肺动脉高压的老年继发孔房缺安全、有效。     

机械性血栓清除术联合同期髂静脉支架植入治疗合并左髂静脉受压综合征的急性下肢深静脉血栓形成

目的：评价经皮机械性血栓清除术联合同期髂静脉支架植入治疗合并左髂静脉受压综合征的急性下肢深静脉血栓（DVT）形成的可行性、安全性及有效性。 方法：选取2015年4月-2017年6月收治左髂静脉受压综合征伴急性下肢DVT的患者33例,发病时间6 h-14 d,平均年龄（57.97±14.44）岁。所有患者均在滤器保护下进行治疗。AngioJet血栓清除术、球囊扩张和髂静脉支架植入均在同期完成,术后保留鞘管予以溶栓治疗,每天复查造影,若血栓完全溶解,取出下腔静脉滤器并结束溶栓。术后第1、3、6、12个月进行门诊随访,行彩色超声和（或）下肢静脉造影检查了解下肢深静脉及髂支架内血流通畅情况。 结果：33例患者均同期完成手术,技术成功率100%,AngioJet抽吸时间为（224.70±72.78）s,溶栓时间（34.00±15.37）h,尿激酶用量（112.58±49.92）万U。33例患者同期植入髂静脉支架33枚。血栓清除率Ⅲ级患者29例,血栓清除率Ⅱ级患者4例。无出血、症状性肺栓等严重并发症发生。术后随访1例患者术后两月血栓复发,32例患者术后随访超声和（或）下肢静脉造影检查提示下肢深静脉及髂静脉支架内血流通畅。 结论：机械性血栓清除术联合同期髂静脉支架植入治疗合并左髂静脉受压综合征的急性下肢深静脉血栓形成是一种安全有效的方法。     

Acute Upper Limb Ischemia due to Cardiac Origin Thromboembolism: the Usefulness of Percutaneous Aspiration Thromboembolectomy via a Transbrachial Approach

Objective

To evaluate the usefulness of percutaneous aspiration thromboembolectomy (PAT) via a transbrachial approach in patients with acute upper limb ischemia.

Materials and Methods

From July 2004 to March 2008, eleven patients with acute upper limb ischemia were enrolled in this study. They were initially treated with thrombolysis (n = 1), PAT (n = 6), or both (n = 4) via a femoral artery approach. However, all of the patients had residual thrombus in the brachial artery, which was subsequently managed by PAT via the transbrachial approach for removal of residual emboli.

Results

Successful re-canalization after PAT via a transbrachial approach was achieved in all patients. Two patients experienced early complications: one experienced a massive hematoma of the upper arm due to incomplete compression and was treated by stent deployment. The other patient experienced a re-occlusion of the brachial artery the day after the procedure due to excessive manual compression of the puncture site, but did not show recurrence of ischemic symptoms in the artery of the upper arm. Clinical success with complete resolution of ischemic symptoms was achieved in all patients.

Conclusion

PAT via a transbrachial approach is a safe and effective treatment for patients with acute upper limb ischemia.     

急性大面积肺动脉血栓栓塞症溶栓治疗的动态CT观察

目的探讨急性大面积肺动脉血栓栓塞症(pulmonarythromboembolism,PTE)溶栓治疗前后CT征象的动态变化,以指导临床治疗。方法回顾分析14例急性大面积PTE患者在溶栓治疗前后以及抗凝治疗随访中的CT表现,对比分析溶栓治疗后2周不同形态栓子的疗效。所有患者分别于溶栓后2周、1个月和3个月后行CT复查,其中8例患者还于治疗后24h行CT复查。结果14例PTE患者共观察到肺动脉血管294支,其中176支肺动脉受累(599%)。溶栓治疗后24h行CT血管造影(CTA)复查的8例患者中1例左肺动脉干栓塞加重,1例左下肺后基底段新出现栓塞;4例肺内片状模糊影和胸腔积液加重,1例新出现胸腔积液。2周后复查栓塞肺动脉中14支中心充盈缺损完全溶解,19支蜂窝状充盈缺损显效13支,32支内缘隆起部分充盈缺损显效20支;63支附壁充盈缺损显效22支,33支完全充盈缺损显效15支,中心充盈缺损、蜂窝状充盈缺损和内缘隆起部分充盈缺损的总体显效率高于附壁充盈缺损和完全充盈缺损的总体显效率(P<001);1个月后复查,171支受累肺动脉完全再通(972%);3个月后复查173支完全再通(983%)。结论CT对诊断PTE、估计栓子新鲜程度以指导治疗和制定复查期限等有重要价值,中心型充盈缺损、蜂窝状充盈缺损和内缘隆起部分充盈缺损是提示新鲜血栓的重要征象。     

Right atrial clot and pulmonary embolism in a patient with COVID-19: A case report

The infection caused by the novel coronavirus (COVID-19) immersed the globe into a widespread pandemic. The disease leads to acute respiratory disease syndrome , hypercoagulation, and cardio-vascular diseases. In this case report, we presented an 80-year-old man with right atrial clot and acute pulmonary embolism, who was diagnosed with COVID-19. The patient was isolated and transferred to the intensive care unit with a diagnosis of submissive pulmonary thromboembolism and right atrial clot following COVID-19 infection. Antibiotics and anticoagulants were administered, and the patient was referred for mechanical thrombectomy. He did not die and after recovery, was discharged with warfarin administration.Preventing thromboembolic events seems to be the first priority in the management of COVID-19 patients. It is necessary to look for strategies to manage and prevent the early occurrence of thromboembolic events in these patients.     

Total Percutaneous Aortic Repair: Midterm Outcomes

The purpose of this study was to examine the immediate and midterm outcomes of percutaneous endovascular repair of thoracic and abdominal aortic pathology. Between December 2003 and June 2005, 21 patients (mean age: 60.4 ± 17.1 years; 15 males, 6 females) underwent endovascular stent-graft insertion for thoracic (n = 13) or abdominal aortic (n = 8) pathology. Preprocedural computed tomographic angiography (CTA) was performed to assess the suitability of aorto-iliac and common femoral artery (CFA) anatomy, including the degree of CFA calcification, for total percutaneous aortic stent-graft repair. Percutaneous access was used for the introduction of 18- to 26-Fr delivery devices. A ‘preclose’ closure technique using two Perclose suture devices (Perclose A-T; Abbott Vascular) was used in all cases. Data were prospectively collected. Each CFA puncture site was assessed via clinical examination and CTA at 1, 6, and 12 months, followed by annual review thereafter. Minimum follow-up was 36 months. Outcome measures evaluated were rates of technical success, conversion to open surgical repair, complications, and late incidence of arterial stenosis at the site of Perclose suture deployment. A total of 58 Perclose devices were used to close 29 femoral arteriotomies. Outer diameters of stent-graft delivery devices used were 18 Fr (n = 5), 20 Fr (n = 3), 22 Fr (n = 4), 24 Fr (n = 15), and 26 Fr (n = 2). Percutaneous closure was successful in 96.6% (28/29) of arteriotomies. Conversion to surgical repair was required at one access site (3.4%). Mean follow-up was 50 ± 8 months. No late complications were observed. By CT criteria, no patient developed a >50% reduction in CFA caliber at the site of Perclose deployment during the study period. In conclusion, percutaneous aortic stent-graft insertion can be safely performed, with a low risk of both immediate and midterm access-related complications.