Clinical Observation on the Treatment of Atrial Fibrillation with Amiodarone Combined with Shenmai Injection (参麦注射液)

Objective: To observe the therapeutic efficacy and safety of amiodarone combined with Shenmai Injection (参麦注射液) on atrial fibrillation. Methods: A total of 351 patients with atrial fibrillation caused by cardiovascular diseases and idiopathic atrial fibrillation were assigned to amiodarone group (control group, 128 cases) and amiodarone combined with Shenmai Injection group (treatment group, 223 cases). The patients in the control group received intravenous injection of 150 mg amiodarone in 10 min, followed by intravenous drip infusion at 1 mg /min and 6 h later at 0.5 mg /min until 48 h or cardioversion. The patients in the treatment group received the same treatment of amiodarone, while in addition, they received an injection of Shenmai Injection of 100 mL simultaneously. Blood pressure, ventricular rate, and cardioversion were observed. Results: The total efficiency rate was 98% (control group) and 99% (treatment group) (P0.05). The mean ventricular rate decreased 23% and 31% in the control group and the treatment group, respectively (P0.05). The mean cardioversion time of the two groups was 570±211 min and 351±123 min, respectively (P0.05). Only mild side effects were observed in both groups. Conclusion: Compared with amiodarone, amiodarone combined with Shenmai Injection takes effect more quickly with low side effects on the treatment of atrial fibrillation.     

Clinical and Experimental Study of the Effect of Xilixin Granule Combined with Radiotherapy on Malignant Tumors

Ｃｌｉｎｉｃａｌ　ａｎｄ　Ｅｘｐｅｒｉｍｅｎｔａｌ　Ｓｔｕｄｙ　ｏｆ　ｔｈｅ　Ｅｆｆｅｃｔ　ｏｆ　Ｘｉｌｉｘｉｎ　Ｇｒａｎｕｌｅ　Ｃｏｍｂｉｎｅｄ　ｗｉｔｈ　Ｒａｄｉｏｔｈｅｒａｐｙ　ｏｎ　Ｍａｌｉｇｎａｎｔ　ＴｕｍｏｒｓＲＥＮＨｕａ－ｙｉ（Ｈｕｎａ...     

Experimental Study on Effect of Angiogenesis with Shenmai Injection

Objective:To study the effect of Shenmai in-jection(SMI)on angiogenesis.Methods:Effect ofSMI on proliferation of fetal bovine serum(FBS)induced bovine aortic endothelial cell(BAECs)and human hepatocarcinoma cell line SMMC-7721     

Comparative Study on the Effects of Small Dose of Aspirin Combined with Ginkgo-damole Injection(银杏达莫注射液) and the Effects of Conventional Dose of Aspirin in Treating Senile Unstable Angina Pectoris

Objective: To evaluate the therapeutic and adverse effect of small dose of aspirin (Asp) combined with Ginkgo-damole injection (GDI,银杏达莫注射液) in treating senile unstable angina pectoris (UA). Methods: One hundred and twenty old in-patients of coronary heart disease with UA were randomly divided into two groups. The 60 patients in the treated group were treated with oral administration of enteric soluble 50 mg Asp once a day and GDI 20 ml per day by intravenous dripping, with 14 days as one therapeutic course, while the other 60 in the control group were treated with enteric soluble Asp 100 mg alone once a day orally. Besides, isosorbide-5-mononitrate 20 mg twice a day was applied to both groups, and the β-ad-renoceptor blocker, blood lipids regulatory agents and nitroglycerin (10 mg by intravenous dripping) were given accordingly. The angina total improving rate, hemorrheologic indexes (whole blood viscosity, plasma viscosity, fibrinogen, platelet aggregation rate), comprehensive clinical terminal     

Clinical Study on Effect of Chinese Herbal Medicine Combined with Hemodialysis in Treating Uremia

Ｉｔｈａｓｂｅｅｎａｎｉｍｐｏｒｔａｎｔｐｒｏｊｅｃｔｆｏｒｒｅｎａｌｐｈｙｓｉｃｉａｎｓｔｈａｔｈｏｗｔｏｉｍｐｒｏｖｅｔｈｅｅｆｆｅｃｔｏｆｈｅｍｏｄｉａｌｙｓｉｓａｎｄｔｈｅｌｉｆｅｑｕａｌｉｔｙｏｆｈｅｍｏｄｉａｌｙｓｉｓｐａｔｉｅｎｔｓｓｉｎｃｅｔｈｅｃｌｉｎｉａｌａｐｐｌｉｃａｔｉｏｎｏｆｈｅｍｏｄｉａｌｙｓｉｓｉｎ 1 960ｓ．Ｉｎｗｅｓｔｅｒｎｍｅｄｉｃｉｎｅ，ｈｉｇｈｌｙｅｆｆｅｃｔｉｖｅｄｉａｌｙｚｅｒ，ｈｉｇｈｆｌｏｗｄｉａｌｙｚｅｒａｎｄｈｉｇｈｌｙｅｆｆｅｃｔｉｖｅｈｅｍｏ…     

Clinical Observation on Effect of Shenqi Fuzheng(参芪扶正)Injection Combined with Chemotherapy in Treating Post-operational Patients with Colorectal Carcinoma

Chemotherapy(CT)is the most impor-tant therapeutic means in treating post-oper-ational patients with colorectal carcinoma(CA),but its efficacy is often affected bythe toxic side-effects of CT agents.TCMcould reinforce body resistance and tonifythe qi,alleviate the toxic side-effects of CT,thus strengthening the efficacy of organismagainst tumor.Shenqi Fuzheng(参芪扶正,     

Clinical Study on Effect of Shenlong Oral Liquid (神龙口服液)Combined with Radiotherapy in Treating Nasopharyngeal Carcinoma

Ｒａｄｉｏｔｈｅｒａｐｙｉｓｔｈｅｆｉｒｓｔｃｈｏｉｃｅｏｆｔｒｅａｔ ｍｅｎｔｏｆｎａｓｏｐｈａｒｙｎｇｅａｌｃａｒｃｉｎｏｍａ （ＮＰＣ）,ｈｏｗｅｖｅｒ,ｎｏｓａｔｉｓｆａｃｔｏｒｙｔｈｅｒａｐｅｕｔｉｃｅｆｆｅｃｔｓｏｆｒａｄｉｏｔｈｅｒａｐｙｈａｖｅｂｅｅｎｇｏｔｔｅｎｔｉｌｌｎｏｗ．Ｆｕｒ ｔｈｅｒｍｏｒｅ,ｒａｄｉｏｔｈｅｒａｐｙｏｆｔｅｎｐｒｏｄｕｃｅｓａｌｏｔｏｆｓｉｄｅｅｆｆｅｃｔｓ,ａｎｄａｌｓｏｉｍｐａｉｒｓｔｈｅｉｍｍｕｎｅｆｕｎｃ ｔｉｏｎｏｆｈｕｍａｎｂｏｄｙ．Ｉｎｏｒ…     

Clinical Study on Effect of Shenmai Injection in Treating Congestive Heart Failure

Objective: To observe the therapeutic effect of Shenmai Injection (SI) in treating congestive heart failure (CHF). Methods: The changes in cAMP, cGMP, serum cardiac troponin T (cTnT, a specific marker reflecting myocardial injury), creatine kinase (CK) and creatine kinase isoenzyme (CK-     

Observation on the Effect of Aidi Injection (爱迪注射液) Combined with Intervention Chemotherapy in Treating Middle-Advanced Hepatocarcinoma

ＦｒｏｍＪｕｎｅ 1 995ｔｏＪａｎｕａｒｙ 2 0 0 0，60ｉｎ ｐａｔｉｅｎｔｓｏｆｍｉｄｄｌｅ ａｄｖａｎｃｅｄｈｅｐａｔｏｃａｒｃｉｎｏｍａｈａｄｂｅｅｎｔｒｅａｔｅｄｗｉｔｈｔｗｏｄｉｆｆｅｒｅｎｔｍｅｔｈｏｄｓａｎｄｃｏｍｐａｒａｔｉｖｅｓｔｕｄｙｗａｓｃｏｎｄｕｃｔｅｄｂｙｔｈｅａｕｔｈｏｒｓ．Ｒｅｓｕｌｔｓｓｈｏｗｅｄｔｈａｔｔｈｅｂｅｔｔｅｒｃｏｍ ｐｒｅｈｅｎｓｉｖｅｅｆｆｅｃｔｗａｓｓｈｏｗｎｂｙｔｈｅｔｒｅａｔｍｅｎｔｏｆＡｉｄｉｉｎｊｅｃｔｉｏｎ（ＡＤＩ）ｃｏｍｂｉｎｅｄｗｉｔｈｉ…     

Clinical Study on Effect of Garlicin in Stabilizing the Carotid Artery Atherosclerotic Plaque in Patients with Primary Hypertension and Coronary Artery Disease

Objective:To investigate the effect of garlicin in treating carotid artery atherosclerotic plaque (GAAP) in patients with primary hypertension and coronary heart disease (PHT-CHD).Methods:Seventynine patients with PHT-CHD were randomly divided into the treated group (39 patients) treated with garlicin and fosinopril and the control group (40 patients) treated with fosinopril alone. The change of CAAP was evaluated by high frequency ultrasonic examination every six months, and the changes of intercellular adhesion molecule-1 (ICAM-1) and high sensitive C-reactive protein (hs-CRP) were measured by ELISA, with the observation proceeding for 52 weeks totally. Results:By the end of the experiment, the number of complex plaques, Crouse integrals, intima-media thickness, serum ICAM-1 and hs-CRP were significantly lower in the treated group than those in the control group with significant difference (P<0.05). Conclusion:Garlicin could stabilize CMP to a certain extent and shows a definite vascular protective effect in patients with PHT-CHD.     

Clinical Study on Effect of Shenfu Injection(参附注射液)in Treating Senile Cerebral Infarction

Objective:To explore the clinical effectand mechanism of Shenfu Injection(SFI)intreating senile cerebral infarction.Methods:Eighty-two aged patients with cerebral in-farction were randomly divided into the trea-ted group treated with SFI and the controlgroup treated with Venoruton.The clinicaleffect was observed,the hemorrheologic and     

A Clinical Study on the Effect of Jinshisan(金石散）in Dissolving Gallstone

ＡＣｌｉｎｉｃａｌＳｔｏｄｙｏｎｔｒｅＥｆｆｅｃｔｏｔＪｉｎｓｎｉｓａｎ（金石散）ｉｎＤｉｓｓｏｌｖｉｎｇＧａｌｌｓｔｏｎｅＡＣｌｉｎｉｃａｌＳｔｏｄｙｏｎｔｒｅＥｆｆｅｃｔｏｔＪｉｎｓｎｉｓａｎ（金石散）ｉｎＤｉｓｓｏｌｖｉｎｇＧａｌｌｓｔｏｎｅＰ...     

Study on Clinical Therapeutic Effect of Composite Salvia Injection Matched with Western Medicine in Treating Diabetic Foot

Study on Clinical Therapeutic Effect of Composite Salvia Injection Matched with Western Medicine in Treating Diabetic Foot@吴汉妮$Union Hospital, Tongji Medical College of Huazhong University of Science and Technology! Wuhan (430022) @孙晖$Union Hospital, Tongji Medical College of Huazhong University of Science and Technology! Wuhan (430022)…     

Clinical Study on the Effect of Shengxueling (生血灵) on Idiopathic Thrombocytopenic Purpura

Idiopathic thrombocytopenic purpura (ITP) isa kind of hemorrhagic disease due to autoimmunedisorder. Adrenal cortical hormone has been thechoice drug for a long time, but its application hasbeen limited because of its adverse reaction and lowremission rate. According to the theory and clini cal experience of TCM, we treated 56 ITP patientswith Shengxueling (生血灵, SXL), gaining bettereffect than with prednisone. The result is reportedas follows.METHODSClinical Material　　E…     

Clinical Study on Protective Effect of Astragalus Injection Plus Ligustrazin in Patients with Myocardial Ischemia Reperfussion Injury

Objective: To investigate the mechanism of protective effect of Astragalus (As) plus ligustrazine (Lt) against myocardial ischemia reperfusion injury (MIRI) during open heart surgery of cardiopulmonary bypass, and the treating principle of MIRI in TCM.Methods: Twenty-four patients were randomly divided into three treated groups and treated with As injection, Lt injection and both (As + Lt) respectively, 6 in each group, and the remainder 6 were taken as control group. Blood samples of them were collected before anesthesia (T1), 10 minutes after occlusion of aorta (T2), 10 minutes(T3) and 30 minutes(T4) after the release, and end of operation (about 180 minutes after release, T5) respectively to test the levels of aspartate aminotransferase ( AST ), lactate dehydrogenase (LDH), creatine kinase (CK), MB isoenzyme of CK (CK-MB), malondialdehyde (MDA) and the activity of Superoxide dismutase ( SOD ), nitric oxide ( NO ), nitric oxide synthetase (NOS).Results: The levels of AST, LDH, CK were reduced in the treated groups, showing significant difference (P< 0.05 or P < 0. 01 ) as compared with those in the control groups. Among them the effect in the AS + Lt group was the best. And NO activity in As group at T5 and As + Lt group at T4, T5 was higher than that in the control group.Conclusion : The mechanism of MIRI is Qi deficiency and blood stasis in TCM, its treating principles should be promoting Qi and removing blood stasis. According to the authors’ study, combined As + Lt therapy is more effective in protecting against MIRI than that using the 2 medicines separately.     

A Study on the Effect of Sterilization of Barber''''s Tools with Ozone Box

ＡＳｔｕｄｙｏｎｔｈｅＥｆｆｅｃｔｏｆＳｔｅｒｉｌｉｚａｔｉｏｎｏｆＢａｒｂｅｒ＇ｓＴｏｏｌｓｗｉｔｈＯｚｏｎｅＢｏｘＷａｎｇＫｅｂｏ，ｅｔａｌ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ，１９９４，１４（１）：５６－５７Ａｂｓｔｒａ...     

Clinical Observation on Nasopharyngeal Carcinoma Treated with Combined Therapy of Radiotherapy and Ginseng Polysaccharide Injection

Ｇｉｎｓｅｎｇｐｏｌｙｓａｃｃｈａｒｉｄｅ（ＧＳＰ），ａｍａｃｒｏ ｍｏｌｅｃｕｌａｒｇｌｕｃｏｓｅｅｘｔｒａｃｔｅｄｆｒｏｍｇｉｎｓｅｎｇ，ｉｓａｎｅｗｔｙｐｅｏｆｉｍｍｕｎｏｒｅｇｕｌａｔｏｒｓｈｏｗｉｎｇｉｍｍｕｎｅｅｎｈａｎｃｉｎｇｅｆｆｅｃｔｉｎｃｌｉｎｉｃａｌｏｂｓｅｒｖａｔｉｏｎ（1）．ＴｈｅｔｈｅｒａｐｅｕｔｉｃｅｆｆｅｃｔｏｆｒａｄｉｏｔｈｅｒａｐｙｃｏｍｂｉｎｅｄｗｉｔｈＧＳＰｉｎｔｒｅａｔｉｎｇｎａｓｏｐｈａｒｙｎｇｅａｌｃａｒｃｉｎｏ ｍａ（ＮＰＣ）ａｎｄｉｔｓｉｎｆｌｕｅ…     

A Clinical Study on the Treatment of Urinary Infection with Zishen Tongli Jiaonang

Objective: To observe the therapeutic effects of Zishen Tongli Jiaonang (滋肾通利胶囊 capsules for nourishing the kidney and promoting urination) for treatment of urinary infection. Method: The treatment group with a control group were randomly set up. 120 patients in the control group were given antibiotics according to drug sensitive tests for orally taking or intravenous drip, while 136 patients in the treatment group were additionally given the capsules on the basis of the above-mentioned treatment. One course of treatment lasted 2 weeks. Statistical analysis on the therapeutic effects was conducted after a two-course treatment. The recurrence rates of the two groups were compared one year later. Results: The total remission rates were respectively 96.3% in the treatment group and 81.7% in the control group (P＜0.05).The recurrence rates one year later were respectively 4.4% in the treatment group and 30.0% in the control group (P＜0.01). Conclusion: The capsules show good effects for urinary infection, especially in the longterm effect.     

A Clinical Study on the Effects and Mechanism of Xuebijing Injection(血必净注射液)in Severe Pneumonia Patients

Objective: To observe the effects of Xuebijing Injection (血必净注射液) in patients with severe pneumonia, and to explore the mechanism. Methods: Eighty cases of severe pneumonia are randomly assigned to the Xuebijing treatment (forty cases) and the control group (forty cases), with the same routine therapy provided in both groups. Clinical effective rates, inflammatory factors and organ function were observed in both groups. Results: The effective rate was higher in Xuebijing group than that of the control group (80.0% vs. 67.5%, P<0.05). As compared with the control group, the LDH, α1-AG, α1-AT levels and the peak body temperature decreased markedly with the Xuebijing treatment going, and the secretion of TNF-α, IL-6, IL-8 was suppressed in Xuebijing group; but no significant difference was found in leptin level. Conclusion: Xuebijing Injection may show a protective effect in patients with severe pneumonia. The mechanism is possibly with the decreased secretion of TNF-α, IL-6, and IL-8.