Relationship between myocardial T2* values and cardiac volumetric and functional parameters in β-thalassemia patients evaluated by cardiac magnetic resonance in association with serum ferritin levels

Purpose

Myocardial T2* cardiovascular magnetic resonance provides a rapid and reproducible assessment of cardiac iron load in thalassemia patients. Although cardiac involvement is mainly characterized by left ventricular dysfunction caused by iron overload, little is known about right ventricular function. The aim of this study was to assess the relationship between T2* value in myocardium and left–right ventricular volumetric and functional parameters and to evaluate the existing associations between left–right ventricles volumetric and functional parameter, myocardial T2* values and blood ferritin levels.

Materials and methods

A retrospective analysis of 208 patients with β-thalassemia major and thalassemia intermedia was performed (109 males and 99 females; mean age 37.7 ± 13 years; 143 thalassemia major, 65 thalassemia intermedia). Myocardial iron load was assessed by T2* measurements, and volumetric functions were analyzed using the steady state free precession sequence.

Results

A significant correlation was observed between EFLV and T2* (p = 0.0001), EFRV and T2* (p = 0.0279). An inverse correlation was present between DVLV and T2* (p = 0.0468), SVLV and T2* (p = 0.0003), SVRV and T2* (p = 0.0001). There was no significant correlation between cardiac T2* and LV–RV mass indices. A significant correlation was observed between T2* and serum ferritin levels (p < 0.001) and between EFLV and serum ferritin (p < 0.05).

Conclusion

Myocardial iron load assessed by T2* cardiac magnetic resonance is associated with deterioration in left–right ventricular function; this is more evident when T2* values fall below 14 ms. CMR appears to be a promising approach for cardiac risk evaluation in TM patients.     

Pancreatic iron stores assessed by magnetic resonance imaging (MRI) in beta thalassemic patients

Purpose

To assess the correlation between MRI findings of the pancreas with those of the heart and liver in patients with beta thalassemia; to compare the pancreas T2* MRI results with glucose and ferritin levels and labile plasma iron (LPI).

Materials and methods

We retrospectively evaluated chronically transfused patients, testing glucose with enzymatic tests, serum ferritin with chemiluminescence, LPI with cellular fluorescence, and T2* MRI to assess iron content in the heart, liver, and pancreas. MRI results were compared with one another and with serum glucose, ferritin, and LPI. Liver iron concentration (LIC) was determined in 11 patients’ liver biopsies by atomic absorption spectrometry.

Results

289 MRI studies were available from 115 patients during the period studied. 9.4% of patients had overt diabetes and an additional 16% of patients had impaired fasting glucose. Both pancreatic and cardiac R2* had predictive power (p < 0.0001) for identifying diabetes. Cardiac and pancreatic R2* were modestly correlated with one another (r² = 0.20, p < 0.0001). Both were weakly correlated with LIC (r² = 0.09, p < 0.0001 for both) and serum ferritin (r² = 0.14, p < 0.0001 and r² = 0.03, p < 0.02, respectively). None of the three served as a screening tool for single observations. There is a strong log–log, or power-law, relationship between ratio of signal intensity (SIR) values and pancreas R2* with an r² of 0.91.

Conclusions

Pancreatic iron overload can be assessed by MRI, but siderosis in other organs did not correlate significantly with pancreatic hemosiderosis.     

Puissance critique de l’enfant prépubère et de l’adulte

Aim

The aim of the study was to compare aerobic and anerobic abilities of prepubertal children and adults with the critical power concept.

Methods

Sixteen children (10.3 ± 0.9 years) and 15 adults (23.5 ± 3.6 years) performed five tests: a maximal-graded test and four constant load exercises until exhaustion. Critical power (CP) and anaerobic-work capacity (CTA) were determined from the power-1/time (P-t) linear relationship.

Results

Determination coefficients for P-t were 0.94 ± 0.05 in children and 0.96 ± 0.04 in adults. PC values were significantly (p < 0.01) lower in children (2.7 ± 0.4 W/kg) than in adults (3.1 ± 0.3 W/kg). CTA values were significantly (p < 0.001) lower in children (136.4 ± 50.8 J/kg) than in adults (247.1 ± 45.7 J/kg).

Conclusion

Satisfying determination coefficients for CP and CTA were found in children and adults. Children have a lower CP and CTA than adults. This result is in accordance with literature.     

Effects of repetitive freeze–thawing cycles on T2 and T2* of the Achilles tendon

Introduction

In this study we sought to evaluate the effects of multiple freezing and thawing cycles on two MR parameters to study Achilles tendon, T2 and T2*.

Materials and methods

Four fresh Achilles tendons were imaged on a 3T clinical scanner and again after 1, 2, 4, and 5 freeze–thaw cycles with spin-echo (SE) and ultrashort echo time (UTE) sequences. Regions of interest were manually drawn over the entire Achilles tendon and mono-exponential curves were used to determine T2 and T2* relaxation times.

Results

There was no statistically significant difference in mean T2 or T2* values between the fresh specimens and after subsequent cycles of freeze–thaw treatment (p > 0.1). Linear regression between SE T2 values at baseline and after successive freeze–thaw cycles demonstrated moderate agreement (r = 0.60) whereas UTE T2* values at baseline and after successive-freeze thaw cycles demonstrated strong agreement (r = 0.92).

Conclusion

These findings suggest that changes between specimens seen in vitro are due to factors other than frozen storage. Furthermore, our results suggest that there is stronger agreement between baseline (fresh) and successive freeze–thaw T2* values of tendon obtained with the UTE technique in comparison to T2 values obtained with a conventional clinical CPMG technique.     

Effets d'une restriction hydrique et alimentaire prolongée (ramadan) sur la performance et les réponses cardiovasculaires au cours d'un exercice incrémental en milieu tropical chaud

Backgroung

Previous studies showed that maximal oxygen uptake and maximal heart rate were not different during prolonged fasting (ramadan) compared to normal feeding period. However, the effect of ramadan on the blood pressure response during incremental exercise has not been investigated.

Objective

This study aimed to evaluate the evolution of blood pressure during incremental trial in ramadan period.

Methods

Twelve young trained male aged 24 ± 4 yrs participated as voluntary subjects. Their anthropometric parameters, maximal aerobic power and maximal heart were measured in fasting and in normal feeding periods during incremental trial on cycle ergometer.

Results

No significant difference was observed in any anthropometric parameter. Maximal aerobic power of fasting period was significantly less (P < 0,05) compared to normal feeding. Heart rate at rest, at maximal exercise and during a 15 min period of recovery was not significantly affected. Systolic blood pressure of fasting period at maximal power was significantly lower than during the control period (P < 0,05).

Conclusion

Ramadan negatively influences the capacity of maximal power and cardiovascular response at maximal power.     

MRI assessment of changes in liver iron deposition post-venesection

Objective

The aim of this study was to determine if changes in hepatic iron content in patients with hemochromatosis pre- and post-venesection could be detected by changes in liver signal intensity with MRI.

Materials and methods

The study was performed with institutional ethics approval and with informed consent. Gradient echo images were performed on 20 patients with hemochromatosis pre- and post-venesection and 10 control subjects: gradient echo T1-weighted in- and out-phases (4.54 (in)/2.27 (out), 167 [TE/TR], Flip 70°) and gradient echo T2* (5/18 [TE/TR], Flip 10°). The liver to muscle signal ratio was compared pre- and post-venesection.

Results

All MRI sequences showed significant correlation between the liver to muscle signal intensity ratio and the serum ferritin pre-venesection [r = −0.70, −0.65, −0.74, −0.72, in/out/T2*r/T2*, respectively]. There was a significant increase on all sequences in the liver to muscle signal intensity ratio post-venesection (p < 0.001). The control group and patients post-venesection had almost identical liver to muscle signal intensity ratios.

Conclusion

The reduction in liver signal intensity caused by iron excess in hemochromatosis returns to normal post-venesection. Measurement of liver to muscle signal intensity ratios may be a useful tool in assessing treatment response in iron overload states.     

Hepatic steatosis assessment with H-spectroscopy and chemical shift imaging at 3.0 T before hepatic surgery: Reliable enough for making clinical decisions?

Purpose

To compare the accuracy of liver fat quantification using chemical shift imaging (CSI) and H1 MR-spectroscopy (MRS) at 3.0 T in patients undergoing liver resection.

Methods

Totally 35 patients were included in this prospective IRB approved study. The histopathologically assessed liver fat was compared to the hepatic fat fractions calculated with CSI (with and without spleen correction) and MRS. Spearman's rank correlation and Fisher z-test were used for correlation analysis. Sensitivity and specificity regarding the detection of marked steatosis were calculated for the different modalities and compared using the McNemar test.

Results

MRS (r = .85) and CSI with spleen correction (r = .85) showed a significantly better correlation (p = .03) with histology compared to CSI without spleen correction (r = .67). Sensitivity and specificity for the detection of marked steatosis was 100% (12/12) and 87% (20/23) for MRS and 92% (11/12) and 83% (19/23) for CSI with spleen correction (p > .12).

Conclusion

For the assessment of hepatic steatosis both CSI with spleen correction and MRS at 3.0 T, show a good correlation with histology. CSI without spleen correction should not be used. Sensitivity and specificity for the detection of marked steatosis are high with both modalities. However, results that are scattered around the cut-off values are not reliable enough for clinical decisions.     

Pulmonary MR imaging with ultra-short TEs: Utility for disease severity assessment of connective tissue disease patients

Purpose

To evaluate the utility of pulmonary magnetic resonance (MR) imaging with ultra-short echo times (UTEs) at a 3.0 T MR system for pulmonary functional loss and disease severity assessments of connective tissue disease (CTD) patients with interstitial lung disease (ILD).

Materials and methods

This prospective study was approved by the institutional review board, and written informed consent was obtained from 18 CTD patients (eight men and ten women) and eight normal subjects with suspected chest disease (three men and five women). All subjects underwent thin-section MDCT, pulmonary MR imaging with UTEs, pulmonary function test and serum KL-6. Regional T2* maps were generated from each MR data set, and mean T2* values were determined from ROI measurements. From each thin-section MDCT data set, CT-based disease severity was evaluated with a visual scoring system. Mean T2* values for normal and CTD subjects were statistically compared by using Student's t-test. To assess capability for pulmonary functional loss and disease severity assessments, mean T2* values were statistically correlated with pulmonary functional parameters, serum KL-6 and CT-based disease severity.

Results

Mean T2* values for normal and CTD subjects were significantly different (p = 0.0019) and showed significant correlations with %VC, %DL_CO, serum KL-6 and CT-based disease severity of CTD patients (p < 0.05).

Conclusion

Pulmonary MR imaging with UTEs is useful for pulmonary functional loss and disease severity assessments of CTD patients with ILD.     

Aspects biologiques des interactions de l’exercice et de la récupération

Subject

The use of Fourier transform infrared spectrometry technique (FT-IR) as a pitch technique of the biological control of short and intense exercises close to those of Rugby matches.

Material and method

In reference to 28 rugbymen of international level, the biological results of three short and intense exercises and two periods of recovery were analyzed by TF-IR. The exercises are: (1) sprints; (2) 12 × 20 m of swerve running; (3) 6 × 30 s of shuttle run.

Results

Lactate, glucose, urea, and to a lesser degree, triglycerides showed a significant evolution. If the evolution of the two first was in conformity with the literature, the increase of urea probably results from the activation of the purins–nucleotides cycle, whereas the evolution of triglycerides is explained by their probable muscular use during periods of active recovery. Among proteins related to the healthy sportsman, only haptoglobin presents a significant variation difficult to explain whereas CRP, orosomucoid and immunoglobulins A, G and M remain close to their rest values.

Conclusion

With the use of FT-IR technique, it is possible to intervene directly on the pitches of the sporting practice to control the biological incidences and to adjust the loads individually. It is also possible to detect inflammatory and immunological problems related to the biomechanical and physiological stresses.     

Hepatic hemangiomas: Factors associated with T2 shine-through effect on diffusion-weighted MR sequences

Purpose

To determine the frequency and factors associated with the presence of T2 shine-through effect in hepatic hemangiomas on diffusion-weighted (DW) magnetic resonance (MR) sequences.

Materials and methods

This retrospective study was approved by institutional review board with waiver of informed consent. One hundred forty-nine consecutive patients with 388 hepatic hemangiomas who underwent a liver MR between January 2010 and November 2011 were included. MR analysis evaluated the lesion characteristics (signal intensities and enhancement patterns (classical, rapidly filling, delayed filling)), the presence of T2 shine-through effect on DW sequences (b values of 0, 150, and 600 s/mm²), and apparent diffusion coefficient (ADC) values. Multivariate analysis was performed to study the factors associated with the T2 shine-through effect.

Results

T2 shine-through effect was observed in 204/388 (52.6%) of hepatic hemangiomas and in 100 (67.1%) patients. Mean ADC value of hemangiomas with T2 shine-through effect was significantly lower than hemangiomas without (2.0 ± 0.48 vs 2.38 ± 0.45, P < .0001). On multivariate analysis, high signal intensity on fat-suppressed T2-weighted fast spin-echo images, hemangiomas with classical or delayed enhancement, and the ADC of the liver were the only significant factors associated with T2 shine-through effect.

Conclusion

T2 shine-through effect is commonly observed in hepatic hemangiomas and is related to hemangiomas characteristics. Radiologists should be aware of this phenomenon which could lead to misdiagnosis. Its presence should not question the diagnosis of hemangiomas when typical MR findings are found.     

T1 mapping for detection of left ventricular myocardial fibrosis in hypertrophic cardiomyopathy: A preliminary study

Purpose

To investigate the diagnostic value of T1 mapping imaging of evaluating fibrosis in patients with hypertrophic cardiomyopathy (HCM).

Materials and methods

21 subjects with HCM and 18 healthy volunteers underwent conventional late gadolinium enhancement (LGE) imaging and T1 mapping imaging. The region of myocardium in HCM is divided into remote area of LGE, peri-LGE, LGE (halo-like LGE and typical patchy LGE). These regions combined with normal volunteers’ myocardium were calculated by the reduced percent of T1 value (RPTV).

Results

The RPTV in healthy volunteers was no significant comparing with that in the remote area of LGE in HCM subjects (3.98 ± 3.19 vs. 3.34 ± 2.75, P > 0.05). There were significant statistical differences in pairwise among the remote area of LGE, peri-LGE, halo-like LGE and typical patchy LGE in the RPTV (P < 0.0001). ROC curves indicated that the T1 mapping imaging has a greater area under the curve comparing with that of traditional LGE imaging (0.975 ± 0.07 vs. 0.753 ± 0.26, P < 0.0001).

Conclusions

HCM has a high prevalence of fibrosis and with varying severity. T1 mapping imaging can be a useful method to evaluate the severity of the fibrosis in HCM.     

Uchi-komi avec charge,une approche physiologique d'un nouveau test spécifique au judo

Objective

The aim of this study was to elaborate and validate a specific test to evaluate the physical condition of judo players.

Subjects and methods

Twenty-three volunteers, males, aged 22 ± 3.62 years old took part in our experiment. They did the progressive test of Leger et al. (1984), vertical Jump test (Sargent test), Australian shuttle run test and a specific judo test.

Results

The observed results showed significant correlations between muscular power and the number of Uchi-komi on the judo test reference scale (R = 0.52, P < 0.01). Furthermore, there were other correlations between the number of Uchi-komi at the two first sets of specific judo test and the anaerobic power represented by the distance covered in 30s at the Australian shuttle test (R = 0.86, P < 0.01), also between the anaerobic capacity represented by the whole distance covered and the total number of Uchi-komi achieved at the judo test (R = 0.88, P < 0.01).

Conclusion

The test reproduces the physiological characteristics of judo fight. It is a good indicator of the judoka's physical fitness and their cardiovascular adaptation in a physical effort.     

Diffusion weighted MRI in chronic viral hepatitis C: Correlation between apparent diffusion coefficient values and histopathological scores

Aim of the work

To assess the utility of hepatic ADC of diffusion weighted MRI in the diagnosis of liver fibrosis in chronic hepatitis C patients and to evaluate its relationship with both the stage of liver fibrosis and grade of necro-inflammation.

Subjects and methods

Forty patients with chronic viral hepatitis C and 30 healthy control group were examined by 1.5 T MRI scanner using DWI at b-values of 100, 400 and 800 s/mm². The mean ADC values of both patients and the control group were correlated to biopsy findings and graded according to METAVIR scoring system.

Results

The mean ADC values of the liver at all b-values were statistically significantly lower in the study group than those of the control group. A strong negative correlation was found between the mean ADC value and the stage of fibrosis. No significant correlation was found between the mean ADC value and the grade of necroinflammation.

Conclusion

The ADC value of diffusion weighted MRI can be used to distinguish between liver parenchyma of patients with chronic viral hepatitis C and healthy subjects and it is useful for estimation of the stage of liver fibrosis but not valuable in estimation of the grade of necro-inflammation.     

The role of MR diffusion in differentiation of malignant and benign hepatic focal lesions

Aim

To determine if focal liver masses could be differentiated as benign or malignant by DWI and ADC maps.

Methods and materials

Sixty focal liver lesions were scanned using 1.5 T MRI. DWI was performed with b 0, b 500 and b 1000 gradients with ADC measurements. Comparison of mean ADC values between each benign and malignant lesion was done. Reference standard of diagnosis was obtained by correlating DWI with histopathologic findings and imaging follow-up. The accuracies of DWI and ADC values were assessed with the Student’s t test, and cut-off values were determined with receiver operating characteristic curve analysis.

Results

When ADC value of 1.0 × 10⁻³ mm²/s was used as a threshold value for differentiation of malignant tumors from benign lesions, sensitivity was 90.3%, specificity 78.57% and accuracy 86.7%. The best result was obtained with the use of ADC cut off value (at b 500) of 1.5 × 10⁻³ mm²/s and ADC cut off value (at b 1000) of 1.0 × 10⁻³ mm²/s, with 90.3% sensitivity, 92.86% specificity, 91.1% accuracy, 96.6% positive predictive value and 81.3% negative predictive value.

Conclusion

DWI and ADC map is a useful tool in differential diagnosis of malignant from benign liver lesions.     

Effets d'une complémentation nutritionnelle en vitamines et minéraux sur la chute de force et les marqueurs biologiques consécutifs à un exercice excentrique chez des personnes âgées

Purpose

The effects of vitamins and minerals complex supplementation on maximal voluntary contraction decrease (FMV) and biological markers following an eccentric exercise at old people.

Method

Sixteen elderly subjects took either placebo (Pl group) or vitamins and minerals (Isoxan Senior, NHS, Rungis, France) (group S) for 21 d before an eccentric exercise and for 3 d after the exercise. The FMV and surface EMG activity (RMS) of the vastus lateralis (VL), vastus médialis (VM) and rectus fémoris (RF) were recorded before (Pre), immediately after (Post), 24 h (Post 24) and 48 h (Post 48) after the exercise. CCVThe creatine kinase (CK), lactate déshydrogénase, malondialdéhyde, and tumor necrosis Factor (TNFα) levels were analyzed.

Results

The reduced MVC (S: 11,2 ± 4,8%; Pl: 17,8 ± 10,4%, P < 0,01) after exercise was associated with a significant reduction in RMS VL, RMS VM and RMS RF values for both groups. A faster FMV recovery appeared at 48 h for the S group (P < 0.05). CK and TNFα values increased in post-exercise.

Conclusion

A dietary supplementation of a vitamin and mineral complex does not attenuate the loss of contractile function immediately after the running exercise, and it may accelerate the recovery of maximal force capacity after 48 h by limiting the post-exercise pro-inflammatory processes.     

Assesment of perfusion in glial tumors with arterial spin labeling; comparison with dynamic susceptibility contrast method

Purpose

Arterial spin labeling perfusion imaging (ASL-PI) is a non-invasive perfusion imaging method that can be used for evaluation and quantification of cerebral blood flow (CBF). Aim of our study was to evaluating the efficiency of ASL in histopathological grade estimation of glial tumors and comparing findings with dynamic susceptibility contrast perfusion imaging (DSC-PI) method.

Methods

This study involved 33 patients (20 high-grade and 13 low-grade gliomas). Multiphase multislice pulsed ASL MRI sequence and a first-passage gadopentetate dimeglumine T2*-weighted gradient-echo single-shot echo-planar sequence were acquired for all the patients. For each patient, perfusion relative signal intensity (rSI), CBF and relative CBF (rCBF) on ASL-PI and relative cerebral blood volume (rCBV) and relative cerebral blood flow (rCBF) values on DSC-PI were determined. The relative signal intensity of each tumor was determined as the maximal SI within the tumor divided by SI within symetric region in the contralateral hemisphere on ASL-PI. rCBV and rCBF were calculated by deconvolution of an arterial input function. Relative values of the lesions were obtained by dividing the values to the normal appearing symmetric region on the contralateral hemisphere. For statistical analysis, Mann–Whitney ranksum test was carried out. Receiver operating characteristic curve (ROC) analysis was performed to assess the relationship between the rCBF-ASL, rSI-ASL, rCBV and rCBF ratios and grade of gliomas. Their cut-off values permitting best discrimination was calculated. The correlation between rCBV, rCBF, rSI-ASL and rCBF-ASL and glioma grade was assessed using Spearman correlation analysis.

Results

There was a statistically significant difference between low and high-grade tumors for all parameters. Correlation analyses revealed significant positive correlations between rCBV and rCBF-ASL (r = 0.81, p < 0.001). However correlation between rCBF and rCBF-ASL was weaker (r = 0.64, p < 0.001).

Conclusion

Arterial spin labeling is an employable imaging technique for evaluating tumor perfusion non-invasively and may be useful in differentiating high and low grade gliomas.     

Effet d'un entraînement en endurance sur les concentrations de l'IGF-1 plasmatique chez le rat

Introduction

The aim of this study was to determine the effects of endurance training on IGF-1, corticosterone and insulin levels in male sedentary and trained rats.

Facts

IGF-1 concentrations decrease after training (p < 0.05), those of corticosterone increase (p < 0.01) whereas insulin levels remain stable.

Conclusion

A short period of endurance training leads to catabolic state with a decrease in IGF-1 concentrations and increase in corticosterone levels.     

Delayed-enhancement magnetic resonance imaging at 3.0 T using 0.15 mmol/kg of contrast agent for the assessment of chronic myocardial infarction

Objective

A recent international, multicenter, double-blinded, randomized trial shows delayed-enhanced magnetic resonance imaging (DE-MRI) using contrast doses of ≥0.2 mmol/kg is effective in the detection and assessment of myocardial infarction (MI), and 0.1 mmol/kg is not enough; intermediate doses between 0.1 and 0.2 mmol/kg have not been tested. The aim of this study was to prospectively test the performance of DE-MRI using 0.15 mmol/kg of contrast agent for the detection of MI.

Materials and methods

A total of 31 consecutive patients with chronic MI underwent DE-MRI at 3.0 T using both 0.15 mmol/kg and 0.2 mmol/kg of contrast agent in random order and on separate days. Infarction segment and infarction size were compared on DE-MRI images using a 17-segment model. Bland–Altman analysis was used to analyze correlation and agreement between global infarct sizes.

Results

DE-MRI showed enhanced myocardium in all the 31 patients with chronic MI. There was no significant difference between the 0.15 mmol/kg and 0.2 mmol/kg images in all 31 patients based on the infarction segment (7.87 ± 2.72 vs. 7.81 ± 2.64, respectively; p = 0.33). There was no significant difference between the infarction size obtained from 0.15 mmol/kg acquisition and that from 0.2 mmol/kg acquisition (16.3 ± 7.8% vs. 16.4 ± 7.9%, respectively; p = 0.87). A strong correlation between the infarction size obtained from 0.15 mmol/kg acquisition and that from 0.2 mmol/kg acquisition was indicated through Bland–Altman analysis.

Conclusion

DE-MRI at 3.0 T using 0.15 mmol/kg of contrast agent is effective for the assessment of MI.     

Energía dual y angioTC de carótidas: calidad,eliminación de hueso y dosis de radiación de 80/140 kV frente a 100/140 kV

Objective

To study the differences in vascular image quality, bone subtraction, and dose of radiation of dual energy CT angiography of the supraaortic trunks using different tube voltages.

Material and methods

We reviewed the CT angiograms of the supraaortic trunks in 46 patients acquired with a 128-slice dual source CT scanner using two voltage protocols (80/140 kV and 100/140 kV). The “head bone removal” tool was used for postprocessing. We divided the arteries into 15 segments. In each segment, we evaluated the image quality of the vessels and the effectiveness of bone removal in multiplanar reconstructions (MPR) and in maximum intensity projections (MIP) with each protocol, analyzing the trabecular and cortical bones separately. We also evaluated the dose of radiation received.

Results

Of the 46 patients, 13 were studied using 80/140 kV and 33 with 100/140 kV. There were no significant differences between the two groups in age or sex. Image quality in four segments was better in the group examined with 100/140 kV. Cortical bone removal in MPR and MIP and trabecular bone removal in MIP were also better in the group examined with 100/140 kV. The dose of radiation received was significantly higher in the group examined with 100/140 kV (1.16 mSv with 80/140 kV vs. 1.59 mSv with 100/140 kV).

Conclusion

Using 100/140 kV increases the dose of radiation but improves the quality of the study of arterial segments and bone subtraction.