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笔者于1994~2003年间.根据中医学理论.应用扶正固本法治疗肝炎后肝硬化腹水92例.取得满意疗效,现分析如下。 相似文献
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肝硬化腹水多为血吸虫病性肝硬化与乙型肝炎后肝硬化引起,为探讨不同病因肝硬化腹水的治疗效果,现将我院1996~1997年收治的89N肝硬化腹水息者的临床资料进行分析.1临床资料89例肝硬化腹水病人,男72例,女17例,年龄25~70岁,平均48岁,病程1个月至26年,占同期住院病例的6%。其中单纯血吸虫病性肝硬化腹水(下称血吸虫性肝硬化)8例(8.99%),血吸虫性肝硬化合并乙型肝炎后肝硬化腹水(下称混合性肝硬化)50例(56.18%),乙型肝炎后肝硬化腹水(下称乙肝后肝硬化)31例(34.83%);轻度腹水31例,中度36例,重度22例,合并… 相似文献
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张克强 《中华医院感染学杂志》2013,23(9)
目的 探讨重型肝炎与肝炎后肝硬化合并感染的临床危险因素,为临床防治感染提供依据.方法 回顾性分析312例重型肝炎和肝炎后肝硬化患者的临床资料,记录患者疾病类型、性别、年龄、住院时间、侵入性操作、血清蛋白水平、白细胞计数、合并其他并发症与感染的相关性.结果 312例患者中80例合并感染,感染率为25.6%,其中>40岁患者感染率为32.1%,明显高于≤40岁的19.0% (P<0.05);住院时间>20 d患者感染率为37.6%,明显高于≤20 d的17.6%(P<0.05);有侵入性操作患者感染率为28.9%,明显高于无侵入性操作的18.2% (P<0.05);血清白蛋白>28 g/L患者感染率为31.8%,明显高于≤28 g/L的21.1%(P<0.05);合并其他并发症患者感染率为30.5%,明显高于未合并其他并发症的20.0% (P<0.05);而感染率与疾病类型、性别以及白细胞计数比较差异无统计学意义.结论 重型肝炎、肝炎后肝硬化患者合并感染与患者的年龄、住院时间、侵人性操作、血清白蛋白水平及合并其他并发症因素密切相关,为临床防治工作提供了一定依据. 相似文献
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目的 观察腹水超滤浓缩回输腹腔技术治疗肝炎肝硬化顽固性腹水患者的临床疗效.方法 将76例肝炎肝硬化顽固性腹水患者随机分为研究组和对照组.研究组在常规治疗基础上,采用腹水超滤浓缩回输腹腔治疗;对照组在常规治疗基础上,采用治疗性腹腔穿刺放腹水治疗.结果 研究组治疗后腹围、体重、24 h尿量、肌酐、血清白蛋白改善情况明显好于对照组(P〈0.05),研究组临床疗效明显好于对照组(P〈0.01).结论 腹水超滤浓缩回输腹腔术是治疗肝硬化腹水的一种有效方法,作为顽固性肝硬化腹水的内科对症治疗措施是一种较好的选择. 相似文献
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目的 探讨乙肝后肝硬化顽固性腹水的治疗.方法 对2002年1月~2005年6月收治的30例乙肝后肝硬化顽固性腹水病例进行回顾性分析.结果 乙肝后肝硬化顽固性腹水治疗效果不佳,病情复杂.与其肝功能状态、门脉高压情况、伴随疾病等多种因素有关,其疾病本身与治疗措施均可引起严重并发症.结论 乙肝后肝硬化顽固性腹水单纯使用利尿剂已达不到有效治疗目的,应采取综合性治疗措施,并尽可能寻找影响腹水消退的原因. 相似文献
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陈士林 《保健医学研究与实践》2017,14(2):77-79
目的比较肝炎后肝硬化(VC)与酒精性肝硬化(AC)患者的临床特征。方法选取鞍山市某医院收治的100例肝硬化患者为研究对象,将50例VC患者作为VC组,将50例AC患者作为AC组,观察2组患者从入院起3个月内的主要临床表现及并发症发生情况。结果 AC组患者脾脏肿大及原发性肝癌发生率均低于VC组,而上消化道出血发生率高于VC组,差异均有统计学意义(P0.05)。结论 VC患者脾脏肿大及原发性肝癌发生率较高,而AC患者上消化道出血发生率较高。因此,在治疗肝硬化患者时,要重视患者疾病分型,以提高治疗效果。 相似文献
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目的 对肝硬化腹水在临床的诊断和治疗方法进行分析.方法 通过对70例肝硬化腹水患者临床资料的回顾性分析,探讨肝硬化腹水的合理有效的治疗方法.结果肝硬化腹水病情复杂且变化快,其中显效41例,有效24例,无效5例.结论 控制钠的摄入量,利尿剂,放腹水并补充蛋白促进血浆胶体渗透压的提高,腹水回输法,腹腔-颈静脉引流,经治疗后效果显著. 相似文献
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结肠癌组织游离氨基酸与肿瘤体积相关性研究 总被引:3,自引:0,他引:3
目的:探讨结肠癌生长对氨基酸代谢的影响以及对某些氨基酸的特殊需求。方法:采用反相高压液相色谱技术测定18例结肠癌病人肿瘤组织20种游离氨基酸含量,与肿瘤体积进行相关性和多元逐步回归分析。结果:结肠癌组织中谷氨酰胺、蛋氨酸、精氨酸、苏氨酸、缬氨酸、亮氨酸、苯丙氨酸、天冬酰胺、丝氨酸含量较正常结肠粘膜组织明显增加(P<0.05),而丙氨酸、色氨酸含量较正常结肠粘膜组织明显减少(P<0.05)。结肠癌组织游离谷氨酰胺、蛋氨酸、精氨酸、缬氨酸、亮氨酸、天冬酰胺、丝氨酸与肿瘤体积呈明显正相关。结论:随着结肠癌生长,肿瘤特别需求谷氨酰胺、蛋氨酸、精氨酸、缬氨酸、亮氨酸、天冬酰胺、丝氨酸,这为结肠癌病人氨酸酸营养液的组成提供了参考资料。 相似文献
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高翠红 《中华临床营养杂志》2014,22(5):293-296
目的 了解乳腺癌患者体内氨基酸代谢特点,以便更合理地给予营养支持.方法 采用日立L-8900型氨基酸自动分析仪,检测55例乳腺癌患者及50例正常人血浆、尿液中游离氨基酸的含量.结果 乳腺癌患者血浆中蛋氨酸含量(48.22±12.90)μmol/L较正常人升高(P=0.04);异亮氨酸(43.07±14.88) μmol/L、亮氨酸(93.22±18.29)μmol/L、缬氨酸(200.86±42.11) μmol/L、精氨酸(46.49±11.79)μmol/L、赖氨酸(107.37±32.61)μmol/L、酪氨酸(29.51 ±18.09) μmol/L、苯丙氨酸(57.39±17.03) μmol/L含量较正常人降低,支链氨基酸/芳香族氨基酸比值1.81±0.81较正常人下降(P=0.04,P=0.01,P=0.04,P=0.00,P=0.01,P=0.02,P=0.00,P=0.04);乳腺癌患者尿液中苯丙氨酸(22.01±4.37)μmol/L、酪氨酸(12.13±5.72) μmol/L、赖氨酸(107.37±32.61)μmol/L含量较正常人升高(P =0.01,P=0.02,P=0.00),亮氨酸(0.84±0.21)μmol/L、缬氨酸(0.50±1.10)μmol/L含量较正常人降低(P=0.04,P=0.01),支链氨基酸/芳香族氨基酸比值1.91±0.60较正常人下降(P=0.03).结论 乳腺癌患者体内存在氨基酸代谢紊乱,乳腺癌患者的“不平衡氨基酸疗法”在营养支持时以补充支链氨基酸和精氨酸为主. 相似文献
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Chika Okada Hiroyasu Iso Junko Ishihara Koutatsu Maruyama Norie Sawada Shoichiro Tsugane 《Journal of epidemiology / Japan Epidemiological Association》2017,27(5):242-247
Background
The Japanese database of food amino acid composition was revised in 2010 after a 24-year interval. To examine the impact of the 2010 revision compared with that of the 1986 revision, we evaluated the validity and reliability of amino acid intakes assessed using a food frequency questionnaire (FFQ).Methods
A FFQ including 138 food items was compared with 7-day dietary records, completed during each distinct season, to assess validity and administered twice at approximately a 1-year interval, to assess reliability. We calculated amino acid intakes using a database that compensated for missing food items via the substitution method. Subjects were a subsample of two cohorts of the Japan Public Health Center-based prospective study. A total of 102 men and 113 women in Cohort I and 174 men and 176 women in Cohort II provided complete dietary records and the FFQ, of whom 101 men and 108 women of Cohort I and 143 men and 146 women of Cohort II completed the FFQ twice.Results
In the comparison of the FFQ with dietary records, the medians (ranges) of energy-adjusted correlation coefficients for validity were 0.35 (0.25–0.43) among men and 0.29 (0.19–0.40) among women in Cohort I, and 0.37 (0.21–0.52) and 0.38 (0.24–0.59), respectively, in Cohort II. Values for reliability were 0.47 (0.42–0.52) among men and 0.43 (0.38–0.50) among women in Cohort I, and 0.59 (0.52–0.70) and 0.54 (0.45–0.61), respectively, in Cohort II.Conclusions
The FFQ used in our prospective cohort study is a suitable tool for estimating amino acid intakes. 相似文献16.
Rondanelli M Opizzi A Antoniello N Boschi F Iadarola P Pasini E Aquilani R Dioguardi FS 《Clinical nutrition (Edinburgh, Scotland)》2011,30(5):571-577
Background & aims
This study assessed the efficacy of supplemented essential amino acids on depressive symptoms, nutrition, muscle function, daily physical activity, and health-related quality of life (HRQoL) of institutionalized elderly patients.Methods
Forty-one patients (58.5% women; mean age 79.8 yrs) with sequelae of coronary artery disease (73%), femoral fracture (34%), were randomly assigned to receive oral essential amino acids 4 gr 2 times a day for 8 weeks or isocaloric placebo. Before randomization and 8 weeks after the protocol started, the following variables were measured: depressive symptoms (Geriatric Depression Scale, GDS), nutritional panel (Mini Nutritional Assessment, MNA; serum albumin and prealbumin levels), muscle strength (Hand Grip, HG), Activity Daily Life (ADL), Quality of Life (SF-36, HRQoL) and amino acid profile.Results
Compared with the placebo group, EAA patients improved nutrition (MNA score 22.6 ± 1.5 post vs 21.8 ± 1.6 pre; p < 0. 04, albumin g/dl 4.04 ± 0.35 post vs 3.88 ± 0.3 pre; p < 0.01), GDS(score 10.3 ± 1.75 post vs 13.85 ± 3.37 pre; p < 0.001), HG (Kg 19.75 ± 1.7 post vs 18.68 ± 1.36 pre; p = 0.001), ADL (p < 0.04) and both physical and mental components of SF-36 (p < 0.002).Conclusions
Oral supplementation with essential amino acids improved several determinants of quality of life in institutionalized elderly patients, including depressive symptoms, nutrition, muscle function and daily life activity. 相似文献17.
The amino acid content of foods commonly consumed by specific populations is rarely measured systematically, especially if we take into account the different ways that foods are usually processed or cooked. The objective of this study is to evaluate the amino acid profile of the representative foods on the Portuguese diet, with a particular focus on indispensable amino acids. We also aim to assess the amino acid intake of the population and the most common sources of amino acids within the Portuguese diet. To achieve these goals, the amino acid intake of Portuguese adults was assessed combining data of food consumption with the food analysis data from samples collected according to the Total Diet Study methodologies. Results of the amino acid profiles of food groups typically consumed in Portugal are reported in this paper. We found that red meat consumption is the most common source of amino acids of the Portuguese population, followed by white meat and fish. The main contribution of individual portions to the recommended intakes of essential amino acids were: cheese, 88%88 %; red meat, 83 %; fatty fish, 81 % and seitan with 74 %. This data could be used to show alternative amino acid sources within commonly consumed foods. 相似文献
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液相色谱-质谱/质谱联用技术分析18种游离氨基酸 总被引:15,自引:0,他引:15
目的:建立氨基酸的液相色谱-质谱检测方法。方法:无需衍生处理,直接用乙腈:水:甲酸(5:95:0.1.v/v/v)为流动相进行反相液相色谱分离,用电喷雾正离子源进行离子化,选择反应监测方式(SRM)对这18种氨基酸的母离子及子离子进行监测,三级四极质谱测定。结果:该方法抗干扰能力强,方法重现性好,RSD0.4%。3.7%,回收率95%~104%,相关系数0.9931-0.9999,检出限0.5~8mol/ml。结论:该方法简单、快速、准确、灵敏,适合测定各种样品中的游离氨基酸。 相似文献
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目的:了解永瓣藤氨基酸的含量,并对不同部位氨基酸的含量进行比较。方法:利用氨基酸分析仪对永瓣藤氨基酸含量进行测量。结果:永瓣藤含有16种氨基酸,包括7种必需氨基酸、4种半必需氨基酸、9种药效氨基酸;叶氨基酸含量高于茎,而嫩茎氨基酸含量一般高于老茎。结论:永瓣藤氨基酸种类齐全,含量较丰富,必需氨基酸与总氨基酸的比值合理,药效氨基酸占总氨基酸的比例高。因此,永瓣藤在医学和营养学上有很高的研究价值。 相似文献
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山东产酸枣仁中微量元素及氨基酸分析 总被引:7,自引:1,他引:7
对山东四个主产区的酸枣仁采用原子吸收分光光度法等进行了微量元素的测定;并用氨基酸自动分析仪对游离氨基酸进行了测定。结果表明,山东不同产地酸枣仁中均含有Fe、Mn、Zn、Se等7种人体必需的微量元素及酪氨酸、蛋氨酸、缬氨酸、苏氨酸等8种人体必需的氨基酸。 相似文献