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1.
The metabolism of sialoglycoproteins and ganglioside (free, oligo-, protein-, and lipid-bound sialic acids, and activity of
sialidase) is studied in plasma and gastric and duodenal mucosa of rats subjected to immobilization stress for 8 days. Sustained
alterations in these parameters are found in severely stressed animals.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N
o
9, pp. 268–269, September, 1994
Presented by S. S. Debov, Member of the Russian Academy of Medical Sciences. 相似文献
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N. S. Strelkov P. N. Sharaev N. G. Naumova P. N. Maksimov 《Bulletin of experimental biology and medicine》1999,127(6):631-632
Serum and local bone indexes of collagen catabolism were considerably increased in rabbit pups with acute stage of tibial
osteomyelitis. Chronic stage of osteomyelitis was characterized by an elevated content of hydroxyproline bound to low-molecular-weight
collagen fragments.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 6, pp. 691–692, June, 1999 相似文献
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L. P. Gorshunova T. M. Khizhnyakova A. V. Nabokova 《Bulletin of experimental biology and medicine》1976,81(3):344-345
A single oral administration of living poliomyelitis vaccine of immunologic type II (Sabin strain) to albino mice weighing 12–14 g is followed by an increase in the free sialic acid content from the 5th to the 20th days and in the bound sialic acid content from the 20th to the 45th day from the beginning of immunization in the small intestine of the vaccinated animals.Laboratory of Immunopathology, D. I. Ivanovskii Institute of Virology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR V. M. Zhdanov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 3, pp. 298–299, March, 1976. 相似文献
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S. M. Napalkova O. V. Artem'eva Ya. V. Kostin S. Ya. Skachilova N. N. Gireva 《Bulletin of experimental biology and medicine》1999,127(2):194-196
Acute toxicity of amino acid-containing antiarrhythmic agents is experimentally studied in mice. Introduction of amino acids
into the antiarrhythmic molecules always reduces their toxicity. However, the same amino acids unequally modulate toxicity
of different antiarrhythmic drugs.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 2, pp. 215–217, February, 1999 相似文献
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Lectin-like properties of the major enamel protein amelogenin suggest that it binds to glycoconjugates in dentinal tubules released at the dentin-enamel junction (DEJ) during enamel formation. Therefore, a detailed mapping of glycosylation in dentinal tubules during tooth formation was undertaken using histochemistry and lectin-binding assays. The tubular content exhibited sialidase-susceptible gamma-metachromasia with Toluidine Blue (pH 2.5) and staining with Alcian Blue (pH 1.0). The presence of sulfate groups was confirmed by benzidine reactions (Bracco-Curti's and tetrazonium assays). Alpha2,3-, alpha2,6- and alpha2,8-sialidases entirely abolished staining with the benzidine reactions. The presence of sialic acids in dentinal tubules was confirmed with the Bial's reaction and sialidase-susceptible binding of Limax flavus lectin suggesting that sialic acids are the major sulfated sugars in the glycoconjguates. Immunostaining with the monoclonal antibody 5-D-4 before and after treatment with chondroitin-4- and chondroitin-6-sulfatase confirmed the presence of keratan sulfate (KS), a sialylated proteoglycan, in dentinal tubules. We suggest that sulfated sialic acids are part of the KSs. The sulfated glycoconjugates are also found in dentin and the DEJ but not in predentin suggesting that amelogenin binds to the sialoconjugate during enamel formation. 相似文献
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The effect of ethimizole on the mobilization of fatty acids and the role of hormones of the pituitary-adrenal system in the lipolytic effect of ethimizole were studied in experiments on rats. The lipid-mobilizing action of ethimizole was well marked in intact, hypophysectomized, and adrenalectomized rats. The effect of the drug disappeared in animals after simultaneous extirpation of the pituitary and adrenals but was restored when these animals were given hydrocotisone. It is concluded that ethimizole has a direct action on the mobilization of fatty acids and that corticosteroids play a permissive role in the lipid-mobilizing effect of ethimizole.Department of Pharmacology, Institute of Experimental Medicine, Academy of Medical Sciences of the USSR, Leningrad. (Presented by Academician of the Academy of Medical Sciences of the USSR S. V. Anichkov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 9, pp. 321–323, September, 1977. 相似文献
10.
The effect of enteral oxygen therapy was studied in rats with acute degeneration of the liver caused by CCl4. Intragastric injection of oxygen foam reduced the severity of poisoning and led to more rapid and complete recovery of the intensity of bile secretion, synthesis of primary bile acids, and their conjugation with amino acids, and improved the stabilizing properties of the bile.Department of Pharmacology, Ternopol' Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR S. V. Anichkov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 10, pp. 419–421, October, 1977. 相似文献
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Nepomnyashchikh GI Levitskii VA Nepomnyashchikh LM Aidagulova SV Naumova LA Belov IY 《Bulletin of experimental biology and medicine》2000,129(4):396-399
Pathomorphological examination of large bronchi in patients with occupational diseases, lung cancer, and in subjects exposed
to radiation revealed structural and functional heterogeneity of the epithelium: the presence of focal atrophy, metaplasia,
hyper- and dysplasia in the same biopsy specimen. This phenomenon was termed as instability of the epithelium. Thickness of
the epithelium greatly varied, especially, in neoplastic processes. Atrophy and epithelial instability phenomenon are interpreted
as morphological markers of ecological and oncological risk.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 4, pp. 470–474, April, 2000 相似文献
13.
T. P. Kulagina I. K. Kolomiitseva V. I. Arkhipov 《Bulletin of experimental biology and medicine》2000,130(3):864-866
The content of lipids in rat cortical tissue homogenate and fraction of neuronal nuclei was determined under normal conditions
and after picrotoxin-induced seizures. Changes in lipid composition of homogenate and nuclear fraction differed considerably.
In homogenate, the content of sphingomyelin, lysophosphatidylcholine, and total phospholipids increased, while the content
of free fatty acid remained unchanged; in the nuclear fraction the total phospholipid content decreased, while the concentration
of free fatty acids increased.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 9, pp. 292–294, September 2000 相似文献
14.
G. I. Oskol'skii M. I. Radivoz A. Yu. Astakhova 《Bulletin of experimental biology and medicine》1997,124(4):1038-1041
Proliferative processes in the gingival mucosa are studied by autoradiography in 55 patients with chronic gingivitis. It is
found that the number of DNA-producing epithelial cells does not change. Increased label intensity in chronic catarrhal and
hypertrophic gingivitis in comparison with the control testifies to a sufficient compensatory reaction. Regenerative processes
are suppressed in chronic atrophic gingivitis. The number of pathological mitoses increases with the development of pathomorphological
changes in all studied types of gingivitis.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 10, pp. 473–476, October, 1997 相似文献
15.
Kulagina TP Kolomiitseva IK Arkhipov VI 《Bulletin of experimental biology and medicine》2000,130(9):864-866
The content of lipids in rat cortical tissue homogenate and fraction of neuronal nuclei was determined under normal conditions
and after picrotoxin-induced seizures. Changes in lipid composition of homogenate and nuclear fraction differed considerably.
In homogenate, the content of sphingomyelin, lysophosphatidylcholine, and total phospholipids increased, while the content
of free fatty acid remained unchanged; in the nuclear fraction the total phospholipid content decreased, while the concentration
of free fatty acids increased.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 9, pp. 292–294, September 2000 相似文献
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M. M. Minnebaev F. I. Mukhutdinova R. M. Minnebaev 《Bulletin of experimental biology and medicine》1994,117(6):584-586
It is shown that in rabbits with fever the lymphatic system is involved together with the circulatory system in the resorption
of metabolic products from intercellular spaces of organs and tissues and in the transport of these products to the general
circulation. In cases of a long-lasting febrile reaction, the toxicity of lymph greatly increases as a consequence of a rise
in its content of creatinine and urea.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N
o
6, pp. 584–586, June 1994
Presented by A. D. Ado, Member of the Russian Academy of Medical Sciences 相似文献
19.
V. V. Popuchiev L. Sh. Safinova N. K. Chumakova I. M. Kvetnoi A. O. Molotkov 《Bulletin of experimental biology and medicine》1998,126(6):1235-1237
The area of the metabolic component of the microcirculatory bed decreases in the adrenal cortex of albino rats intoxicated
with 2,4-dichlorophenoxyacetic acid (a herbicide), as revealed by quantitative histochemical analysis. This decrease is paralleled
by a decrease in the production of adrenal steroids.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 126, No. 12, pp. 666–668, December, 1998 相似文献
20.
T. G. Sazontova Xiang Qun Fu L. M. Belkina Yu. V. Arkhipenko F. Z. Meerson 《Bulletin of experimental biology and medicine》1993,116(4):1197-1200
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N
o
10, pp. 350–352, October, 1993 相似文献