Molecular Analysis of edicinally-Used Chinese and Japanese Curcuma Based on 18S rRNA Gene and trnK Gene Sequences

ＧｅｎｕｓＣｕｒｃｕｍａｏｆｔｈｅｆａｍｉｌｙＺｉｎｇｉｂｅｒａｃｅａｅｃｏｎｓｉｓｔｓｏｆａｂｏｕｔ 70ｓｐｅｃｉｅｓｉｎｔｈｅｗｏｒｌｄ ,ｏｆｗｈｉｃｈｍｏｒｅｔｈａｎｔｅｎａｒｅｄｉｓｔｒｉｂｕｔｅｄｏｒｃｕｌｔｉｖａｔｅｄｉｎＣｈｉｎａ[1] ａｎｄＪａｐａｎ[2 ] .ＳｅｖｅｒａｌｈｅｒｂａｌｄｒｕｇｓｕｓｅｄｆｒｅｑｕｅｎｔｌｙａｒｅｄｅｒｉｖｅｄｆｒｏｍｔｈｅＣｕｒｃｕｍａｓｐｅｃｉｅｓ.ＩｎＣｈｉｎａ ,“Ｊｉａｎｇｈｕａｎｇ”ｆｒｏｍｔｈｅｒｈｉ ｚｏｍｅｏｆＣｕｒｃｕｍａｌｏｎｇａ ,“Ｐｉａｎｊｉａｎｇｈｕａｎｇ”ｆｒｏｍｔｈｅｓｌｉｃｅｄｒｈｉｚｏｍｅｏｆＣ .ｗｅｎｙｕｊｉｎ ,“Ｅｚｈｕ”ｆｒｏｍｔｈｅｒｈｉｚｏｍｅｓｏｆＣ .ｐｈａｅｏｃａｕｌｉｓ,Ｃ .ｗｅｎｙｕｊｉｎｏｒＣ .ｋｗａｎｇｓｉｅｎｓｉｓ,ａｎｄ“Ｙｕｊｉｎ”ｆｒｏｍｔｈｅｔｕｂｅｒｓｏｆＣ .ｗｅｎｙｕｊｉｎ ,Ｃ .ｌｏｎｇａ ,Ｃ .ｋｗａｎｇｓｉｅｎｓｉｓｏｒＣ .ｐｈａｅｏｃａｕｌｉｓａｒｅｉｎｕｓｅ .[3] ＩｎＪａｐａｎ ,“Ｇａｊｕｔｓｕ”ｆｒｏｍｔｈｅｒｈｉｚｏｍｅｏｆＣ .ｚｅｄｏａｒ...     

In vitro and in vivo anticancer potential and molecular targets of the new colchicine analog ⅢM-067

Objective: The current study evaluated various new colchicine analogs for their anticancer activity and to study the primary mechanism of apoptosis and in vivo antitumor activity of the analogs with selective anticancer properties and minimal toxicity to normal cells.Methods: Sulforhodamine B(SRB) assay was used to screen various colchicine analogs for their in vitro cytotoxicity. The effect of N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(pyrrolidine-1-yl)5,6,7,9-tetrahydrobenzo[a] heptalene-7-yl] acetami...     

Supercritical fluid extraction of essential oil from the fruits of Bupleurum chinense DC. and their characterization by GC/MS

IntroductionChaihuhasbeenusedasoneofthecommontraditionalchinesemedicinesandisoftenemployedtotreatcoldswithfever,alternatingchillsandfever,feelingoffullnessandchestoppression,andhypochondriasis[1 ] .Itssaikopaponins ,essentialoilhavebeenwellinvestigated .10ursane typetriterpeneglyco sides,19oleanane typetriterpeneglycosidesfromthefruitsofBupleurumrotundifoliumhavebeenisolated ,inaddition ,ursane typetriterpeneglycosideswereshowedtopossessantiprolifera tiveactivity[2 ] .Toourknowledge ,thechemic…     

Medium- and long-term efficacy of ligustrazine plus conventional medication on ischemic stroke： a systematic review and meta-analy- sis

OBJECTIVE： To evaluate the medium- to long-term efficacy of ligustrazine plus conventional medicine treating ischemic stroke. METHODS： Randomized controlled trials （RCTs） testing ligustrazine in the treatment of acute isch- emic stroke were retrieved from Cochrane Library, PubMed, Excerpta Medica Database, Chinese Medi- cal Journal Database, Chinese Biomedical Data- base, China National Knowledge Infrastructure Da- tabase, and Chinese Clinical Trial Register, and then identified by the inclusive and exclusive criteria. The quality of trials was assessed with the Co- chrane Handbook 5.1, a risk of bias assessment toot. RevMan 5.1 was used for meta-analysis.RESULTS： Three RCTs involving 643 patients were included. Compared to conventional medicine treatment alone, ligustrazine plus conventional medicine treatment showed significant difference in reduction of stroke recurrence either at the end of 1-year follow-up [RR=0.42, 95% CI （0.18, 0.94）, P〈 0.05] or 3-years observation [RR=0.48, 95% C/（0.27, 0.83）, P〈0.05]. The ligustrazine group also showed higher survival rate [RR=1.67, 95% CI （1.02, 0.2.71）, P〈0.05] and significantly better effective rate [RR= 1.28, 95% CI（1.10, 1.50）, P〈0.05] than that of the control group at the end of 1 year visit. Only one tri- al conducted safety assessment and no adverse events were reported. The methodological quality of all the trials included was generally poor. CONCLUSION： The findings provided evidence that the combination of ligustrazine and conven- tional medication was medium- and long-term ben- eficial to the patients suffering ischemic stroke. But more RCTs of high quality are needed to further prove the efficacy and safety of using ligustrazine for ischemic stroke.     

LECTURES ON ACUPUNCTURE──Part Ⅰ Fundamentals of Acupuncture and Moxibustion Lecture Seven The Three Yin Meridians of the Foot

TheSpleenMeridianofFoot-Taiyin1.TheMeridian[Course]Themeridianstartsfromthemedialtipofthebigtoe.Alongthemedialaspectofthefoot,goingthroughtheregioninfrontofthemedialmalleolus,itascendstothemedialaspectoftheleg.Followingtheposteriorborderofthetibia,itcrossestothefrontoftheLiverMeridi-anofFoot-Jueyinatapoint8cunabovetheme-dialmalleollis.Passingthroughthemedialante-rioraspectofthethigh,themeridianenterstheabdomen,thenthespleen,whichitisdependenton,andconnectswiththestomach.Goingupa-longthesi…     

EFFICACY OF ACUPUNCTURE THERAPY ON A, B AND O BLOOD GROUPS ──Relationship between A, B, O blood groups and the acupuncture therapy

Acupuncturehasbeenusedforover2000years forawidevarietyofcomplaintswithminimalsideef fects.Clinicallyithasbeenobservedthatpatients havingsimilarailmentsrespondtoacupuncturethera pyinvaryingdegrees.Tofindoutthebasisofsuch variationofefficacyofacupuncturetherapy,surveyof patientswithABObloodgroupswastakenup.Inhu manbeingthechromosome9isaverypopulargene(ABOgene)thatdeterminesourbloodgroups.Link ofbloodgroupswithsomediseasesisknown,e.g.carcinomaofstomachismostfrequentlyseeninpeo plewithgroupA[1]…     

WFAS Signing Cooperation Agreement with the Republic of Belarus and Belarusian Medical Academy of Post-Graduate Education

Prof. Deng Liangyue, the President of WFAS held a meeting with Prof. Alexander P. Sivakou, the Head Specialist on Acupuncture and Non-Traditional Methods of Diagnosis and Treatment, Ministry of Health of Republic of Belarus and President of Belarus Association of Acupuncture and Traditional Medicine and Halynnikau Vjacheslav V. working in Belarusian Medical Academy of Post-Graduate Education on April 6^th.[第一段]     

《后汉书·华佗传》释译

[原文] 華佗,字元化,沛國譙人也[1] ,一名旉[2] .[15] 疾秽:病毒.遊學徐土[3] ,兼通數經[4] .曉養性之術[5] ,年且百歲,而[16] 傅:附着,涂上.神膏:有神效的膏药.猶有壯容,時人以為仙.沛相陳珪舉孝廉[6] ,太尉黃琬[17] 创:伤口.辟[7] ,皆不就.     

The metabolism of constituents of Huangqin- Tang decoction,a traditional Chinese medicinal preparation,in conventional, germ-free and gnotobiote mice

ＩｎｔｒｏｄｕｃｔｉｏｎＩｎｔｅｓｔｉｎａｌｂａｃｔｅｒｉａｐｌａｙａｎｅｓｓｅｎｔｉａｌｒｏｌｅｉｎｔｈｅｍｅｔａｂｏｌｉｓｍｏｆｍａｎｙｇｌｙｃｏｓｉｄｅｓｉｎｖａｒｉｏｕｓｍｅｄｉｃｉｎａｌｈｅｒｂｓｔｏｔｈｅｉｒａｇｌｙｃｏｎｅｓ[1] .Ｓｏｍｅｇｌｙｃｏｓｉｄｅｓｏｆｈｅｒｂｓａｒｅｃｏｎｓｉｄｅｒｅｄｔｏｂｅｍａｉｎｃｏｍｐｏ ｎｅｎｔｓｉｎｍａｎｉｆｅｓｔａｔｉｏｎｏｆｔｈｅｉｒｍｅｄｉｃｉｎｅｅｆｆｅｃｔｓ[2 ] .Ｉｎｐｒｅｖｉｏｕｓｐａｐｅｒ ,ｕｓｉｎｇａｎＨＰＬＣｍｅｔｈｏｄｅｓ ｔａｂｌｉｓｈｅｄｉｎｏｕｒｌａｂｏｒａｔｏｒｙ ,1 5ｃｈｅｍｉｃａｌｃｏｍｐｏｎｅｎｔｓｉｎｃｌｕｄｉｎｇｔｈｅｏｒｉｇｉｎａｌｃｏｍｐｏｕｎｄｓｉｎｔｈｅｔｒａ ｄｉｔｉｏｎａｌＣｈｉｎｅｓｅｍｅｄｉｃｉｎａｌｐｒｅｐａｒａｔｉｏｎＨｕａｎｇｑｉｎ ＴａｎｇａｎｄｔｈｅｉｒｍｅｔａｂｏｌｉｔｅｓｂｙＨＩＢｗｅｒｅｓｉ ｍｕｌｔａｎｅｏｕｓｌｙｉｄｅｎｔｉｆｉｅｄａｎｄｄｅｔｅｒｍｉｎｅｄ .ＴｈｅｒｅｓｕｌｔｓｓｈｏｗｅｄｔｈａｔｔｈｅｇｌｙｃｏｓｉｄｅｓｏｆＨｕａｎｇｑｉｎ ＴａｎｇＢＧ ,ＷＧ...     

Noninvasive identificational diagnosis of diabetic nephropathy and non-diabetic renal disease based on clinical characteristics of Traditional Chinese Medicine symptom pattern and conventional medicine

OBJECTIVE: To study the clinical characteristics relating to differential diagnosis of diabetic nephropathy(DN) and non-diabetic renal disease(NDRD). METHODS: The subjects were patients with type 2 diabetes mellitus(T2DM) complicated with chronic kidney disease(CKD). Western medical history data and Traditional Chinese Medicine(TCM) symptom pattern were collected, and logistic regression was used to analyze. RESULTS: Blood deficiency pattern [odds ratio(OR) = 2.269, P = 0.017] and Qi stagnation ...     

EFFECTS OF ACUMOXI ON IL2-IFN-NKC IMMUNOREGULATORY NETWORK AND ITS RELATED MACROPHAGE-IL1-Th NETWORK AND ON TUMOR——Observation on the Effect of Acumoxi on the Macrophage-IL1-Th Network and on the Metastasis of Hepatoma

Resultsofstudiesinrecentyearsdemon stratethatinthetreatmentoftumor,acupunc tureandmoxibustioncannotonlyrelievepainsandreducesidereactionsofradiotherapyandchemotherapybutalsoenhancetheimmunologicfunctionofcancer patientstoinhibittumorgrowth[1 ,2 ] .However,studiesonIL2 IFN NKCimmunologicnetworkhaverarelyorneverbeenreporteduptonow .Followingareourlat estresearchresultsinthisfield .1　MATERIALSANDMETHODS1 .1　Materials1 .1 .1TumorstrainsMicebearingascitictypehepatoma (H2 2 )areprovid…     

Electrochemical Behaviors of Quercetin and Kaempferol in Neutral Buffer Solution

Ｑｕｅｒｃｅｔｉｎａｎｄｋａｅｍｐｆｅｒｏｌ,ｆｌａｖｏｎｏｌｓ,ａｒｅｐｒｅｄｏｍｉｎａｎｔｉｎｖｅｇｅｔａｂｌｅｓａｎｄｆｒｕｉｔｓ ,ａｎｄａｒｅｃｏｍ ｐｏｎｅｎｔｓｉｎｔｈｅｈｕｍａｎｄｉｅｔ .[1] Ｔｈｅｙａｒｅｒｅｐｏｒｔｅｄｔｏｂｅｐｏｔｅｎｔａ     

和厚朴酚注射剂制备工艺和含量测定的研究

和厚朴酚(honokiol)是我国传统中药厚朴(Magnolia officinalis Rehd.et Wils.)与凹叶厚朴(M.officinalis Rehd.et Wils var.biloba Rehd.et Wils.)中提取分离得到的木脂素类化合物,具有肌肉松弛[1]、抗焦虑[2]、中枢抑制[3]、抗氧化[4,5,6,7]、抗心律失常[8,9]、抗肿瘤[10,11]等多种药理活性.     

LECTURES ON ACUPUNCTURE Part Ⅰ Fundamentals of Acupuncture and Moxibustion Lecture Four The Three Yang Meridians of the Foot (Part One)

ⅠThe Stomach Meridianof Foot-Yangming1. The Meridian[Course] Starting from the side of thenose, the meridian then descends from the in-fraorbital region to enter the upper gum. It thencomes out and goes around the lips to reach theangle of the mandible and the forehead. The de-scending portion of the meridian starts from themandible, goes along the throat, enters thesupraclavicular fossa. It then further passesthrouth the diaphragm, and finally connectswith its pertaining organ, the stomach and itsinteriorly-exteriorly related organ, the spleen.     

墨西哥民族药(续一)

101.Bromelia karatas L.野凤梨,凤梨科。野生草本。叶或根:浸剂口服用于胃病和胆病。[4]237102.Brugmansia candida Pers.白曼陀罗木,茄科。叶:用于止泻,治疗胃肠疾病。[15]68103.Bryophyllum pinnatum(Lam.)Kurtz落地生根,景天科。叶:外敷用于新生儿炎症、丘疹、创伤。[4]237104.Buddleja americana L.美洲醉鱼草,马钱科。野生灌木。叶:外洗用于肌炎、皮炎、子宫炎等。[1]82,[4]237,[7]72105.Buddleja sessiliflora H.B.K.无柄花醉鱼草,马钱科。嫩叶:煎剂口服用于小儿慢性腹泻。[9]112106.Bunchosia biocellata Schlecht.二眼邦乔木…     

Lectures on Acupuncture Part Ⅰ Fundamentals of Acupuncture and Moxibustion Lecture Two The Three Yin Meridians of the Hand

The Lung Meridian of Hand─Taiyin 1.The Meridian [Course] Starting from the stomach（themiddle portion of the body）,going downward toconnect with the large intestine,then turninghack to the lung,its pertaining organ;risingfrom there along the,trachea to the laterosuperi-or part of the the anterior wall of the chest; thenpassing along the radial side of the palmar aspectof the arm to the tip of the thumb.     

北京高峰论坛现场救护第一目击者行动

正主题:救在身边Part.1[现场救护第一目击者行动主题论坛]Part.2[首届亲子急救夏令营(北京站)]Part.3[养老机构护理员(社区服务中心)急救培训活动]Part.4[老年急救大学堂]Part.5["健康中国"杯第一目击者现场急救技能比武]Part.6["救"在身边rap赛]Superviser指导单位国家卫健委疾控局北京市疾控中心     

约旦、墨西哥和多米尼加等国的民族药(续一)

151.Laurus nobilis L.月桂,樟科。叶和果实:约旦用于降血糖和治疗关节炎。叶:多米尼加用于治疗肿瘤:[1]139;[2]292152.Lavandula officinalis Chaix et Kitt.药用薰衣草,唇形科。油:约旦用于治疗偏瘫。叶和花:约旦用于通经。[1]139;[2]292153.Lawsonia inermis L.散沫花,千屈菜科。叶:约旦用于治疗创伤、出血、真菌病。[1]139154.Lepidium sativum L.家独行菜,十字花科。种子:约旦用于催欲、护发,治疗胃痛。[1]139155.Lepidium virginicum L.北美独行菜,十字花科。种子:多米尼加用于治疗子宫肿瘤。[2]291     

巴西、圭亚那、拉丁美洲部分国家及西班牙民族药使用概况(续二)

239.Matayba oppositifolia(A. Rich.)Britton对叶马泰木(拟),无患子科,皮煎洗治毒虫蜇咬。[5]335240.Matricaria chamonilla L. 母菊,菊科,全株煎服治疼痛和胃溃疡。[3]97241.Melicoccus bijugatus Jacq. 两对蜜果,无患子科,叶或种子煎服收敛止泻。[3]104242.Melochia villosa(Mill.)Fawc. d Rendle柔毛马松子,梧桐科,叶煎服治感冒和胃溃疡。[3]105243.Mentha citrata Erhr. 柠檬留兰香,唇形科,叶煎服治胃痛。[5]333244.Miconia albicans(Sw.)Triana白米孔丹(拟),野牡丹科,叶水煎洗局部治皮肤病。[3]102     

202 乌干达、澳大利亚和阿根廷等国的民族药(续一)

171.Euphorbia drummondii Boiss.烧大戟,大戟科。全草:治疗发热、痢疾、慢性腹泻、风湿病、生殖器溃疡、皮肤溃疡、疣。[3]27、[4]152172.Euphorbia hirta L.飞扬草,大戟科。全草:浸剂口服治疗胃痛、腹泻、细菌性和阿米巴痢疾。[2]288、294173.Euphorbia systiloides合柱大戟,大戟科。叶:煎剂饭前口服治疗蛔虫病。[1]63174.Euphorbia tirucalli L.绿玉树,大戟科。全草:榨汁外洗治疗疣、皮疹、溃疡疼痛。[2]288175.Exocarpos aphyllus R.Br.无叶外果檀,檀香科。茎:治疗感冒、痨病、溃疡疼痛。[4]153176.Fagara rhoifolia(Lam.)Engl.漆…